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Bacterial Proteomics: From Cell Division to Novel Antibiotic Targets

Funding: 2005: $200,000
2006: $100,000

Project Member(s): Harry, E.

Funding or Partner Organisation: Australian Research Council (ARC Linkage Projects)
Proteome Systems Ltd (Proteome Systems Partner Funds)

Start year: 2005

Summary: When a cell divides it is essential that each newborn cell gets a complete copy of the DNA. To ensure that this happens, cell division must be tightly controlled. It is not known how this occurs in bacteria. However, if we knew what molecules were involved in this control, we could target them to kill harmful bacteria. This project aims to identify such regulatory molecules as candidate targets for antimicrobial agents, with a view to developing powerful, novel antibiotics to protect us from the imminent threat of bioterrorism and antibiotic-resistant bacteria.

FOR Codes: Microbiology