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Chip Liquid Chromatography, Inductively Coupled Plasma, Mass Spectrometry: A new a micro fluidic chip-based technology for trace element speciation

Project Member(s): Doble, P.

Funding or Partner Organisation: Agility Management Pty Ltd (Agilent Technologies Australia)

Start year: 2010

Summary: This proposal will develop a new micro fluidic chip-based technology for the speciation of trace elements for environmental risk control, biochemistry, clinical chemistry, medicine, and food industry applications. An interface between a chip based liquid chromatograph and an inductively coupled plasma mass spectrometer will be developed. This new technology will have superior resolution, sensitivity and robustness than existing technologies by eliminating capillary flow connections and fittings. The chip format will provide a convenient modular platform for multidimensional separations. Analysis time can be massively reduced by multiplexing, i.e. by employing multiple separation columns on chip for multiple discrete speciation experiments.

FOR Codes: Analytical Biochemistry, Neurosciences not elsewhere classified, Biochemistry and Cell Biology, Expanding Knowledge in the Physical Sciences, Nervous System and Disorders, Occupational Health