Microparticles and Selective Trait Dominance in Multidrug Resistant Cancers - APP1007613 - GNT1007613
Funding or Partner Organisation: National Health & Medical Research Council (NHMRC Project Grants)
Start year: 2011
Publications:
Lu, JF, Pokharel, D & Bebawy, M 2017, 'A novel mechanism governing the transcriptional regulation of ABC transporters in MDR cancer cells', Drug Delivery and Translational Research, vol. 7, no. 2, pp. 276-285.
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Roseblade, A, Ung, A & Bebawy, M 2017, 'Synthesis and in vitro biological evaluation of thiosulfinate derivatives for the treatment of human multidrug-resistant breast cancer', Acta Pharmacologica Sinica, vol. 38, no. 10, pp. 1353-1368.
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Lu, JF, Pokharel, D, Padula, MP & Bebawy, M 2016, 'A novel method to detect translation of membrane proteins following microvesicle intercellular transfer of nucleic acids', Journal of Biochemistry, vol. 160, no. 5, pp. 281-289.
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Pokharel, D, Padula, M, Lu, J, Jaiswal, R, Djordjevic, S & Bebawy, M 2016, 'The Role of CD44 and ERM Proteins in Expression and Functionality of P-glycoprotein in Breast Cancer Cells', Molecules, vol. 21, no. 3, pp. 290-290.
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Gong, J, Jaiswal, R, Dalla, P, Luk, F & Bebawy, M 2015, 'Microparticles in cancer: A review of recent developments and the potential for clinical application', SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, vol. 40, pp. 35-40.
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Lu, JF, Pokharel, D & Bebawy, M 2015, 'MRP1 and its role in anticancer drug resistance', DRUG METABOLISM REVIEWS, vol. 47, no. 4, pp. 406-419.
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Lu, JF, Pokharel, D, Luk, F & Bebawy, M 1970, 'Functional translation of total RNA packaged in microparticles shed from multidrug resistant cancer cells', CLINICAL CANCER RESEARCH, AACR Precision Medicine Series: Drug Sensitivity and Resistance: Improving Cancer Therapy; June 18-21, 2014; Orlando, FL, AMER ASSOC CANCER RESEARCH, Orlando, FL.
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Jaiswal, R, Grau, GER & Bebawy, M 2014, 'Cellular communication via microparticles: role in transfer of multidrug resistance in cancer', FUTURE ONCOLOGY, vol. 10, no. 4, pp. 655-669.
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Gong, J, Luk, F, Jaiswal, R, George, AM, Grau, GER & Bebawy, M 2013, 'Microparticle drug sequestration provides a parallel pathway in the acquisition of cancer drug resistance', EUROPEAN JOURNAL OF PHARMACOLOGY, vol. 721, no. 1-3, pp. 116-125.
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Jaiswal, R, Luk, F, Dalla, PV, Grau, GER & Bebawy, M 2013, 'Breast Cancer-Derived Microparticles Display Tissue Selectivity in the Transfer of Resistance Proteins to Cells', PLOS ONE, vol. 8, no. 4, pp. 1-10.
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Li, CCY, Eaton, SA, Young, PE, Lee, M, Shuttleworth, R, Humphreys, DT, Grau, GE, Combes, V, Bebawy, M, Gong, J, Brammah, S, Buckland, ME & Suter, CM 2013, 'Glioma microvesicles carry selectively packaged coding and non-coding RNAs which alter gene expression in recipient cells', RNA BIOLOGY, vol. 10, no. 8, pp. 1333-1344.
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Lu, JF, Luk, F, Gong, J, Jaiswal, R, Grau, GER & Bebawy, M 2013, 'Microparticles mediate MRP1 intercellular transfer and the re-templating of intrinsic resistance pathways', PHARMACOLOGICAL RESEARCH, vol. 76, pp. 77-83.
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Gong, J, Jaiswal, R, Mathys, J-M, Combes, V, Grau, GER & Bebawy, M 2012, 'Microparticles and their emerging role in cancer multidrug resistance', CANCER TREATMENT REVIEWS, vol. 38, no. 3, pp. 226-234.
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Jaiswal, R, Gong, J, Sambasivam, S, Combes, V, Mathys, J-M, Davey, R, Grau, GER & Bebawy, M 2012, 'Microparticle-associated nucleic acids mediate trait dominance in cancer', FASEB JOURNAL, vol. 26, no. 1, pp. 420-429.
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Jaiswal, R, Luk, F, Gong, J, Mathys, J-M, Grau, GER & Bebawy, M 2012, 'Microparticle conferred microRNA profiles - implications in the transfer and dominance of cancer traits', MOLECULAR CANCER, vol. 11, pp. 1-13.
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FOR Codes: Pharmaceutical Sciences, Cancer and Related Disorders, Clinical health