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Mechanisms of impaired bronchodilator response associated with fatty acid intake in obese asthma

Project Member(s): Oliver, B.

Funding or Partner Organisation: National Health & Medical Research Council (NHMRC Project Grants)

Start year: 2015

Summary: The effects of dietary fatty acids on bronchodilator responsiveness in asthma will be examined.

Publications:

Rutting, S, Xenaki, D, Malouf, M, Horvat, JC, Wood, LG, Hansbro, PM & Oliver, BG 2019, 'Short-chain fatty acids increase TNF╬▒-induced inflammation in primary human lung mesenchymal cells through the activation of p38 MAPK.', American journal of physiology. Lung cellular and molecular physiology, vol. 316, no. 1, pp. L157-L174.
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Rutting, S, Zakarya, R, Bozier, J, Xenaki, D, Horvat, JC, Wood, LG, Hansbro, PM & Oliver, BG 2019, 'Dietary Fatty Acids Amplify Inflammatory Responses to Infection through p38 MAPK Signaling', AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY, vol. 60, no. 5, pp. 554-568.
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Rutting, S, Xenaki, D, Lau, E, Horvat, J, Wood, LG, Hansbro, PM & Oliver, BG 2018, 'Dietary omega-6, but not omega-3, polyunsaturated or saturated fatty acids increase inflammation in primary lung mesenchymal cells', AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, vol. 314, no. 6, pp. L922-L935.
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Rutting, S, Horvat, J, Wood, L, Hansbro, P & Oliver, B 2018, 'The effect of dietary fatty acids on inflammation in primary lung mesenchymal cells', EUROPEAN RESPIRATORY JOURNAL, International Congress of the European-Respiratory-Society, EUROPEAN RESPIRATORY SOC JOURNALS LTD, Paris, France.
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Rutting, S, Horvat, J, Wood, L, Hansbro, P & Oliver, B 2018, 'The effect of dietary fatty acids on respiratory infection in human lung cells', EUROPEAN RESPIRATORY JOURNAL, International Congress of the European-Respiratory-Society, EUROPEAN RESPIRATORY SOC JOURNALS LTD, Paris, France.
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Rutting, S, Xenaki, D, Ge, Q, Wood, L, Hansbro, P & Oliver, B 2017, 'DIETARY OMEGA-6, BUT NOT OMEGA-3 POLYUNSATURATED OR SATURATED FATTY ACIDS INCREASE INFLAMMATION IN HUMAN PULMONARY FIBROBLASTS', RESPIROLOGY, WILEY, pp. 17-17.

Arora, S, Haghi, M, Young, PM, Kappl, M, Traini, D & Jain, S 2016, 'Highly respirable dry powder inhalable formulation of voriconazole with enhanced pulmonary bioavailability', EXPERT OPINION ON DRUG DELIVERY, vol. 13, no. 2, pp. 183-193.
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Tang, FSM, Foxley, GJ, Gibson, PG, Burgess, JK, Baines, KJ & Oliver, BG 2015, 'Altered Innate Immune Responses in Neutrophils from Patients with Well- and Suboptimally Controlled Asthma', MEDIATORS OF INFLAMMATION.
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Keywords: asthma

FOR Codes: Biochemistry and Cell Biology, Preventive Medicine