Mechanisms of impaired bronchodilator response associated with fatty acid intake in obese asthma

Project Member(s): Oliver, B.

Funding or Partner Organisation: National Health & Medical Research Council (NHMRC Project Grants)

Start year: 2015

Summary: The effects of dietary fatty acids on bronchodilator responsiveness in asthma will be examined.

Publications:

Rutting, S, Xenaki, D, Malouf, M, Horvat, JC, Wood, LG, Hansbro, PM & Oliver, BG 2019, 'Short-chain fatty acids increase TNFα-induced inflammation in primary human lung mesenchymal cells through the activation of p38 MAPK', American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 316, no. 1, pp. L157-L174.
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Rutting, S, Zakarya, R, Bozier, J, Xenaki, D, Horvat, JC, Wood, LG, Hansbro, PM & Oliver, BG 2019, 'Dietary Fatty Acids Amplify Inflammatory Responses to Infection through p38 MAPK Signaling', American Journal of Respiratory Cell and Molecular Biology, vol. 60, no. 5, pp. 554-568.
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Rutting, S, Xenaki, D, Lau, E, Horvat, J, Wood, LG, Hansbro, PM & Oliver, BG 2018, 'Dietary omega-6, but not omega-3, polyunsaturated or saturated fatty acids increase inflammation in primary lung mesenchymal cells', American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 314, no. 6, pp. L922-L935.
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Rutting, S, Horvat, J, Wood, L, Hansbro, P & Oliver, B 1970, 'The effect of dietary fatty acids on inflammation in primary lung mesenchymal cells', Airway Cell Biology and Immunopathology, ERS International Congress 2018 abstracts, European Respiratory Society, Paris, France.
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Rutting, S, Horvat, J, Wood, L, Hansbro, P & Oliver, B 1970, 'The effect of dietary fatty acids on respiratory infection in human lung cells', Airway Cell Biology and Immunopathology, ERS International Congress 2018 abstracts, European Respiratory Society, Paris, FRANCE.
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Rutting, S, Xenaki, D, Ge, Q, Wood, L, Hansbro, P & Oliver, B 1970, 'DIETARY OMEGA‐6, BUT NOT OMEGA‐3 POLYUNSATURATED OR SATURATED FATTY ACIDS INCREASE INFLAMMATION IN HUMAN PULMONARY FIBROBLASTS', Respirology, Wiley, pp. 17-17.
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Arora, S, Haghi, M, Young, PM, Kappl, M, Traini, D & Jain, S 2016, 'Highly respirable dry powder inhalable formulation of voriconazole with enhanced pulmonary bioavailability', Expert Opinion on Drug Delivery, vol. 13, no. 2, pp. 183-193.
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Tang, FSM, Foxley, GJ, Gibson, PG, Burgess, JK, Baines, KJ & Oliver, BG 2015, 'Altered Innate Immune Responses in Neutrophils from Patients with Well- and Suboptimally Controlled Asthma', Mediators of Inflammation, vol. 2015, pp. 1-11.
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Keywords: asthma

FOR Codes: Biochemistry and Cell Biology, Preventive Medicine, Preventive medicine

Acknowledgement of Country

UTS acknowledges the Gadigal people of the Eora Nation, the Boorooberongal people of the Dharug Nation, the Bidiagal people and the Gamaygal people, upon whose ancestral lands our university stands. We would also like to pay respect to the Elders both past and present, acknowledging them as the traditional custodians of knowledge for these lands.