Interactions between aberrant transcriptional programs and methylation in primary myelodysplasia and leukaemia

Project Member(s): Beck, D.

Funding or Partner Organisation: National Health & Medical Research Council (NHMRC Early Career Fellowships)

Start year: 2015

Summary: Interactions between aberrant transcriptional programs and methylation in primary myelodysplasia and leukaemia

Publications:

Chiu, SK, Orive, SL, Moon, MJ, Saw, J, Ellis, S, Kile, BT, Huang, Y, Chacon, D, Pimanda, JE, Beck, D, Hamilton, JR, Tremblay, CS & Curtis, DJ 2019, 'Shared roles for Scl and Lyl1 in murine platelet production and function', Blood, vol. 134, no. 10, pp. 826-835.
View/Download from: Publisher's site

Kumar, P, Beck, D, Galeev, R, Thoms, JAI, Talkhoncheh, MS, de Jong, I, Unnikrishnan, A, Baudet, A, Subramaniam, A, Pimanda, JE & Larsson, J 2019, 'HMGA2 promotes long-term engraftment and myeloerythroid differentiation of human hematopoietic stem and progenitor cells', Blood Advances, vol. 3, no. 4, pp. 681-691.
View/Download from: Publisher's site

Thoms, JAI, Beck, D & Pimanda, JE 2019, 'Transcriptional networks in acute myeloid leukemia', Genes, Chromosomes and Cancer, vol. 58, no. 12, pp. 859-874.
View/Download from: Publisher's site

Beck, D, Thoms, JAI, Palu, C, Herold, T, Shah, A, Olivier, J, Boelen, L, Huang, Y, Chacon, D, Brown, A, Babic, M, Hahn, C, Perugini, M, Zhou, X, Huntly, BJ, Schwarzer, A, Klusmann, J-H, Berdel, WE, Wörmann, B, Büchner, T, Hiddemann, W, Bohlander, SK, To, LB, Scott, HS, Lewis, ID, D'Andrea, RJ, Wong, JWH & Pimanda, JE 2018, 'A four-gene LincRNA expression signature predicts risk in multiple cohorts of acute myeloid leukemia patients', Leukemia, vol. 32, no. 2, pp. 263-272.
View/Download from: Publisher's site

Chiu, SK, Saw, J, Huang, Y, Sonderegger, SE, Wong, NC, Powell, DR, Beck, D, Pimanda, JE, Tremblay, CS & Curtis, DJ 2018, 'A novel role for Lyl1 in primitive erythropoiesis', Development, vol. 145, no. 19.
View/Download from: Publisher's site

Jing, D, Huang, Y, Liu, X, Sia, KCS, Zhang, JC, Tai, X, Wang, M, Toscan, CE, McCalmont, H, Evans, K, Mayoh, C, Poulos, RC, Span, M, Mi, J, Zhang, C, Wong, JWH, Beck, D, Pimanda, JE & Lock, RB 2018, 'Lymphocyte-Specific Chromatin Accessibility Pre-determines Glucocorticoid Resistance in Acute Lymphoblastic Leukemia', Cancer Cell, vol. 34, no. 6, pp. 906-921.e8.
View/Download from: Publisher's site

Liu, Q, Thoms, JAI, Nunez, AC, Huang, Y, Knezevic, K, Packham, D, Poulos, RC, Williams, R, Beck, D, Hawkins, NJ, Ward, RL, Wong, JWH, Hesson, LB, Sloane, MA & Pimanda, JE 2018, 'Disruption of a −35 kb Enhancer Impairs CTCF Binding and MLH1 Expression in Colorectal Cells', Clinical Cancer Research, vol. 24, no. 18, pp. 4602-4611.
View/Download from: Publisher's site

Liu, K, Beck, D, Thoms, JAI, Liu, L, Zhao, W, Pimanda, JE & Zhou, X 2017, 'Annotating function to differentially expressed LincRNAs in myelodysplastic syndrome using a network-based method', Bioinformatics, vol. 33, no. 17, pp. 2622-2630.
View/Download from: Publisher's site

Schwarzer, A, Emmrich, S, Schmidt, F, Beck, D, Ng, M, Reimer, C, Adams, FF, Grasedieck, S, Witte, D, Käbler, S, Wong, JWH, Shah, A, Huang, Y, Jammal, R, Maroz, A, Jongen-Lavrencic, M, Schambach, A, Kuchenbauer, F, Pimanda, JE, Reinhardt, D, Heckl, D & Klusmann, J-H 2017, 'The non-coding RNA landscape of human hematopoiesis and leukemia', Nature Communications, vol. 8, no. 1, pp. 1-17.
View/Download from: Publisher's site

Beck, D, Thoms, J, Palu, C, Herold, T, Shah, A, Olivier, J, Boelen, L, Huang, Y, Chacon, D, Brown, A, Babic, M, Hahn, C, Perugini, M, Zhou, X, Huntly, B, Berdel, W, Woermann, B, Buechner, T, Hiddemann, W, Bohlander, S, Scott, H, Lewis, I, D'Andrea, R, Wong, J & Pimanda, J 1970, 'INTEGRATIVE ANALYSIS OF LINCRNA EXPRESSION IN 922 ACUTE MYELOID LEUKEMIA PATIENTS REVEALS MULTIPLE PROGNOSTIC GENE SIGNATURES', HAEMATOLOGICA, pp. 208-209.

FOR Codes: Bioinformatics, Blood Disorders, Cancer and Related Disorders, Bioinformatics and computational biology, Clinical health