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Superresolution light microscope for deep view functional analyses of cancer cells and their microenvironment: a springboard for high resolution correlative microscopy studies in cancer research.

Project Member(s): Valenzuela, S.

Funding or Partner Organisation: Cancer Institute NSW (Cancer Institute NSW - Research Equipment Grant)

Start year: 2016

Summary: Seeing is believing: Microscopic analysis is a cornerstone of distinguishing diseased tissue from healthy tissue. Technological advances in microscopes now enable us to probe ever deeply into individual cells, to identify and analyse biological factors that regulate disease processes such as cancer. Cutting-edge confocal super-resolution light microscopy will produce highly detailed, 3-dimensional images of cells and their internal compartments, and will allow us to analyse proteins and nucleic acids of importance to cancer initiation and progression. We anticipate that these studies will lead to new discoveries about how cancer cells behave and how they respond or resist cancer treatment.

FOR Codes: Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified, Biochemistry and Cell Biology