Glycine Transport Inhibitors for the Treatment of Pain
Project Member(s): Rawling, T.
Funding or Partner Organisation: National Health & Medical Research Council (NHMRC Project Grants)
National Health & Medical Research Council (NHMRC Project Grants)
Start year: 2018
Publications:
Wilson, BS, Peiser-Oliver, J, Gillis, A, Evans, S, Alamein, C, Mostyn, SN, Shimmon, S, Rawling, T, Christie, MJ, Vandenberg, RJ & Mohammadi, SA 2022, 'Peripheral Administration of Selective Glycine Transporter-2 Inhibitor, Oleoyl-D-Lysine, Reverses Chronic Neuropathic Pain but Not Acute or Inflammatory Pain in Male Mice', Journal of Pharmacology and Experimental Therapeutics, vol. 382, no. 3, pp. 246-255.
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Wilson, KA, Mostyn, SN, Frangos, ZJ, Shimmon, S, Rawling, T, Vandenberg, RJ & O’Mara, ML 2021, 'The allosteric inhibition of glycine transporter 2 by bioactive lipid analgesics is controlled by penetration into a deep lipid cavity', Journal of Biological Chemistry, vol. 296, pp. 100282-100282.
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Gallagher, CI, Sheipouri, D, Shimmon, S, Rawling, T & Vandenberg, RJ 2020, 'Identification of N-acyl amino acids that are positive allosteric modulators of glycine receptors', Biochemical Pharmacology, vol. 180, pp. 114117-114117.
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FOR Codes: Medicinal and Biomolecular Chemistry, Human Pharmaceutical Products