Understanding why in-utero exposure to inhaled oxidants predispose people to develop asthma and COPD

Project Member(s): Oliver, B., Chen, H., Faiz, A.

Funding or Partner Organisation: National Health & Medical Research Council (National Health Medical Research Council)
National Health & Medical Research Council (National Health Medical Research Council)

Start year: 2019

Publications:

Feng, M, Padula, MP, Asaad, SA, Bai, X, Cranfield, C, Town, SEL, Saad, S, Oliver, BG, George, J & Chen, H 2025, 'Prolonged exposure to low-dose traffic-derived PM2.5 causes fatty liver disorder in mice', Journal of Environmental Sciences.
View/Download from: Publisher's site

Oliver, BG, Huang, X, Yarak, R, Bai, X, Wang, Q, Zakarya, R, Reddy, KD, Donovan, C, Kim, RY, Morkaya, J, Wang, B, Lung Chan, Y, Saad, S, Faiz, A, Reyk, DV, Verkhratsky, A, Yi, C & Chen, H 2024, 'Chronic maternal exposure to low-dose PM2.5 impacts cognitive outcomes in a sex-dependent manner', Environment International, vol. 191, pp. 108971-108971.
View/Download from: Publisher's site

Chaaya, R, Steele, JR, Oliver, BG, Chen, H & Machaalani, R 2023, 'Effects of e-vapour and high-fat diet on the immunohistochemical staining of nicotinic acetylcholine receptors, apoptosis, microglia and astrocytes in the adult male mouse hippocampus', Journal of Chemical Neuroanatomy, vol. 132, pp. 102303-102303.
View/Download from: Publisher's site

Bai, X, Chen, H & Oliver, BG 2022, 'The health effects of traffic-related air pollution: A review focused the health effects of going green', Chemosphere, vol. 289, pp. 133082-133082.
View/Download from: Publisher's site

Chen, H, Oliver, BG, Pant, A, Olivera, A, Poronnik, P, Pollock, CA & Saad, S 2022, 'Effects of air pollution on human health – Mechanistic evidence suggested by in vitro and in vivo modelling', Environmental Research, vol. 212, pp. 113378-113378.
View/Download from: Publisher's site

Chen, H, Van Reyk, D, Oliveira, A, Chan, YL, Town, SEL, Rayner, B, Pollock, CA, Saad, S, George, J, Padula, MP & Oliver, BG 2022, 'Sex-Dependent Responses to Maternal Exposure to PM2.5 in the Offspring', Antioxidants, vol. 11, no. 11, pp. 2255-2255.
View/Download from: Publisher's site

Thomson, S, Chan, YL, Yi, C, Wang, B, Machaalani, R, Oliver, BG, Gorrie, CA & Chen, H 2022, 'Impact of High Fat Consumption on Neurological Functions after Traumatic Brain Injury in Rats', Journal of Neurotrauma, vol. 39, no. 21-22, pp. 1547-1560.
View/Download from: Publisher's site

Chen, H, Wang, B, Li, G, Steele, JR, Stayte, S, Vissel, B, Chan, YL, Yi, C, Saad, S, Machaalani, R & Oliver, BG 2021, 'Brain health is independently impaired by E-vaping and high-fat diet', Brain, Behavior, and Immunity, vol. 92, pp. 57-66.
View/Download from: Publisher's site

Wang, B, Chan, Y-L, Li, G, Ho, KF, Anwer, AG, Smith, BJ, Guo, H, Jalaludin, B, Herbert, C, Thomas, PS, Liao, J, Chapman, DG, Foster, PS, Saad, S, Chen, H & Oliver, BG 2021, 'Maternal Particulate Matter Exposure Impairs Lung Health and Is Associated with Mitochondrial Damage', Antioxidants, vol. 10, no. 7, pp. 1029-1029.
View/Download from: Publisher's site

Wang, B, Chen, H, Xenaki, D, Liao, J, Cowie, C & Oliver, BG 2021, 'Differential inflammatory and toxic effects in-vitro of wood smoke and traffic-related particulate matter from Sydney, Australia', Chemosphere, vol. 272, pp. 129616-129616.
View/Download from: Publisher's site

Zakarya, R, Chan, YL, Rutting, S, Reddy, K, Bozier, J, Woldhuis, RR, Xenaki, D, Van Ly, D, Chen, H, Brandsma, C-A, Adcock, IM & Oliver, BG 2021, 'BET proteins are associated with the induction of small airway fibrosis in COPD', Thorax, vol. 76, no. 7, pp. 647-655.
View/Download from: Publisher's site

Li, G, Chan, YL, Wang, B, Saad, S, George, J, Oliver, BG & Chen, H 2020, 'E‐cigarettes damage the liver and alter nutrient metabolism in pregnant mice and their offspring', Annals of the New York Academy of Sciences, vol. 1475, no. 1, pp. 64-77.
View/Download from: Publisher's site

Wang, B, Chan, YL, Zhou, S, Saad, S, Chen, H & Oliver, BG 2020, 'Offspring sex affects the susceptibility to maternal smoking-induced lung inflammation and the effect of maternal antioxidant supplementation in mice', Journal of Inflammation, vol. 17.
View/Download from: Publisher's site

Wang, B, Chen, H, Chan, YL & Oliver, BG 2020, 'Is there an association between the level of ambient air pollution and COVID-19?', American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 319, no. 3, pp. L416-L421.
View/Download from: Publisher's site

Wang, B, Chen, H, Chan, YL, Wang, G & Oliver, BG 2020, 'Why Do Intrauterine Exposure to Air Pollution and Cigarette Smoke Increase the Risk of Asthma?', Frontiers in Cell and Developmental Biology, vol. 8.
View/Download from: Publisher's site

Zakarya, R, Sapkota, A, Chan, YL, Shah, J, Saad, S, Bottle, SE, Oliver, BG, Gorrie, CA & Chen, H 2020, 'Nitroxides affect neurological deficits and lesion size induced by a rat model of traumatic brain injury', Nitric Oxide, vol. 97, pp. 57-65.
View/Download from: Publisher's site

Zakarya, R, Chan, YL, Chen, H, Brandsma, C-AA, Adcock, IM & Oliver, BGG 2020, 'BET Protein Propagated Histone Acetylation Mediates ECM Changes in COPD Airways', American Thoracic Society, pp. A6431-A6431.
View/Download from: Publisher's site

Chen, H, Chan, YL, Oliver, BG, Pollock, CA & Saad, S 2019, 'Maternal Smoking and Fetal Brain Outcome: Mechanisms and Possible Solutions' in Preedy, V (ed), Neuroscience of Nicotine, Elsevier, New York, pp. 9-16.
View/Download from: Publisher's site

Bozier, J, Rutting, S, Xenaki, D, Peters, M, Adcock, I & Oliver, BG 2019, 'Heightened response to e-cigarettes in COPD', ERJ Open Research, vol. 5, no. 1, pp. 00192-2018.
View/Download from: Publisher's site

Chan, YL, Wang, B, Chen, H, Ho, KF, Cao, J, Hai, G, Jalaludin, B, Herbert, C, Thomas, PS, Saad, S & Oliver, BGG 2019, 'Pulmonary inflammation induced by low-dose particulate matter exposure in mice', American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 317, no. 3, pp. L424-L430.
View/Download from: Publisher's site

Chen, H, Burke, C, Donovan, C, Faiz, A, Saad, S & Oliver, BG, 'E-Cigarette Vapour Alters High-Fat Diet-Induced Systemic Inflammatory Responses but Has No Effect on High-Fat Diet-Induced Changes in Gut Microbiota', Nutrients, vol. 15, no. 7, pp. 1783-1783.
View/Download from: Publisher's site

Chen, H, Chan, YL, Thorpe, AE, Pollock, CA, Saad, S & Oliver, BG, 'Inhaled or Ingested, Which Is Worse, E-Vaping or High-Fat Diet?', Frontiers in Immunology, vol. 13.
View/Download from: Publisher's site

Chen, H, Li, G, Chan, YL, Zhang, HE, Gorrell, MD, Pollock, CA, Saad, S & Oliver, BG, 'Differential Effects of ‘Vaping’ on Lipid and Glucose Profiles and Liver Metabolic Markers in Obese Versus Non-obese Mice', Frontiers in Physiology, vol. 12.
View/Download from: Publisher's site

Chen, H, Nguyen, LT, Feng, M, Wang, B, Xu, B, Yarak, RA, Chan, YL, Viswanathan, S, Komala, MG, Pollock, CA, Oliver, BG & Saad, S, 'Cross-Generational Impact of Maternal Exposure to Low Level of PM_2.5 on Kidney Health', American Journal of Nephrology, pp. 1-14.
View/Download from: Publisher's site

Chen, H, Oliver, BG, Pant, A, Olivera, A, Poronnik, P, Pollock, CA & Saad, S, 'Particulate Matter, an Intrauterine Toxin Affecting Foetal Development and Beyond', Antioxidants, vol. 10, no. 5, pp. 732-732.
View/Download from: Publisher's site

Donovan, C, Bai, X, Chan, YL, Feng, M, Ho, K-F, Guo, H, Chen, H & Oliver, BG, 'Tenascin C in Lung Diseases', Biology, vol. 12, no. 2, pp. 199-199.
View/Download from: Publisher's site

Feng, M, Bai, X, Thorpe, AE, Nguyen, LT, Wang, M, Oliver, BG, Chou, ASY, Pollock, CA, Saad, S & Chen, H, 'Effect of E-Vaping on Kidney Health in Mice Consuming a High-Fat Diet', Nutrients, vol. 15, no. 14, pp. 3140-3140.
View/Download from: Publisher's site

FOR Codes: Cell Development, Proliferation and Death, Respiratory System and Diseases (incl. Asthma), Cell development, proliferation and death, Clinical health