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Understanding why in-utero exposure to inhaled oxidants predispose people to develop asthma and COPD

Project Member(s): Oliver, B., Chen, H., Faiz, A.

Funding or Partner Organisation: National Health & Medical Research Council (National Health Medical Research Council)
National Health & Medical Research Council (National Health Medical Research Council)

Start year: 2019

Publications:

Bai, X, Chen, H & Oliver, BG 2022, 'The health effects of traffic-related air pollution: A review focused the health effects of going green', Chemosphere, vol. 289, pp. 133082-133082.
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Chen, H, Oliver, BG, Pant, A, Olivera, A, Poronnik, P, Pollock, CA & Saad, S 2022, 'Effects of air pollution on human health – Mechanistic evidence suggested by in vitro and in vivo modelling', Environmental Research, vol. 212, pp. 113378-113378.
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Chen, H, Wang, B, Li, G, Steele, JR, Stayte, S, Vissel, B, Chan, YL, Yi, C, Saad, S, Machaalani, R & Oliver, BG 2021, 'Brain health is independently impaired by E-vaping and high-fat diet', Brain, Behavior, and Immunity, vol. 92, pp. 57-66.
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Wang, B, Chan, Y-L, Li, G, Ho, KF, Anwer, AG, Smith, BJ, Guo, H, Jalaludin, B, Herbert, C, Thomas, PS, Liao, J, Chapman, DG, Foster, PS, Saad, S, Chen, H & Oliver, BG 2021, 'Maternal Particulate Matter Exposure Impairs Lung Health and Is Associated with Mitochondrial Damage', Antioxidants, vol. 10, no. 7, pp. 1029-1029.
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Wang, B, Chen, H, Xenaki, D, Liao, J, Cowie, C & Oliver, BG 2021, 'Differential inflammatory and toxic effects in-vitro of wood smoke and traffic-related particulate matter from Sydney, Australia', Chemosphere, vol. 272, pp. 129616-129616.
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Zakarya, R, Chan, YL, Rutting, S, Reddy, K, Bozier, J, Woldhuis, RR, Xenaki, D, Van Ly, D, Chen, H, Brandsma, C-A, Adcock, IM & Oliver, BG 2021, 'BET proteins are associated with the induction of small airway fibrosis in COPD', Thorax, vol. 76, no. 7, pp. 647-655.
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Li, G, Chan, YL, Wang, B, Saad, S, George, J, Oliver, BG & Chen, H 2020, 'E‐cigarettes damage the liver and alter nutrient metabolism in pregnant mice and their offspring', Annals of the New York Academy of Sciences, vol. 1475, no. 1, pp. 64-77.
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Wang, B, Chan, YL, Zhou, S, Saad, S, Chen, H & Oliver, BG 2020, 'Offspring sex affects the susceptibility to maternal smoking-induced lung inflammation and the effect of maternal antioxidant supplementation in mice', Journal of Inflammation, vol. 17, no. 1.
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Wang, B, Chan, YL, Zhou, S, Saad, S, Chen, H & Oliver, BG 2020, 'Offspring sex affects the susceptibility to maternal smoking-induced lung inflammation and the effect of maternal antioxidant supplementation in mice', Journal of Inflammation, vol. 17.
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Wang, B, Chen, H, Chan, YL & Oliver, BG 2020, 'Is there an association between the level of ambient air pollution and COVID-19?', American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 319, no. 3, pp. L416-L421.
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Wang, B, Chen, H, Chan, YL, Wang, G & Oliver, BG 2020, 'Why Do Intrauterine Exposure to Air Pollution and Cigarette Smoke Increase the Risk of Asthma?', Frontiers in Cell and Developmental Biology, vol. 8.
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Zakarya, R, Sapkota, A, Chan, YL, Shah, J, Saad, S, Bottle, SE, Oliver, BG, Gorrie, CA & Chen, H 2020, 'Nitroxides affect neurological deficits and lesion size induced by a rat model of traumatic brain injury', Nitric Oxide, vol. 97, pp. 57-65.
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Zakarya, R, Chan, YL, Chen, H, Brandsma, C-AA, Adcock, IM & Oliver, BGG 1970, 'BET Protein Propagated Histone Acetylation Mediates ECM Changes in COPD Airways', D28. COPD: FROM PATHOGENESIS TO PROGNOSIS, American Thoracic Society 2020 International Conference, May 15-20, 2020 - Philadelphia, PA, American Thoracic Society.
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Bozier, J, Rutting, S, Xenaki, D, Peters, M, Adcock, I & Oliver, BG 2019, 'Heightened response to e-cigarettes in COPD', ERJ Open Research, vol. 5, no. 1, pp. 00192-2018.
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Chan, YL, Wang, B, Chen, H, Ho, KF, Cao, J, Hai, G, Jalaludin, B, Herbert, C, Thomas, PS, Saad, S & Oliver, BGG 2019, 'Pulmonary inflammation induced by low-dose particulate matter exposure in mice', American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 317, no. 3, pp. L424-L430.
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Chen, H, Chan, YL, Thorpe, AE, Pollock, CA, Saad, S & Oliver, BG, 'Inhaled or Ingested, Which Is Worse, E-Vaping or High-Fat Diet?', Frontiers in Immunology, vol. 13.
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Chen, H, Li, G, Chan, YL, Zhang, HE, Gorrell, MD, Pollock, CA, Saad, S & Oliver, BG, 'Differential Effects of ‘Vaping’ on Lipid and Glucose Profiles and Liver Metabolic Markers in Obese Versus Non-obese Mice', Frontiers in Physiology, vol. 12.
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Chen, H, Oliver, BG, Pant, A, Olivera, A, Poronnik, P, Pollock, CA & Saad, S, 'Particulate Matter, an Intrauterine Toxin Affecting Foetal Development and Beyond', Antioxidants, vol. 10, no. 5, pp. 732-732.
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Thomson, S, Chan, YL, Yi, C, Wang, B, Machaalani, R, Oliver, BG, Gorrie, CA & Chen, H, 'Impact of High Fat Consumption on Neurological Functions after Traumatic Brain Injury in Rats', Journal of Neurotrauma.
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FOR Codes: Cell Development, Proliferation and Death, Respiratory System and Diseases (incl. Asthma), Cell development, proliferation and death, Clinical health