Unravelling the behavioural and brain mechanisms of compulsive disorders, and new ways to treat them

Project Member(s): Bradfield, L.

Funding or Partner Organisation: National Health & Medical Research Council (NHMRC - Ideas Grants)
National Health & Medical Research Council (NHMRC - Ideas Grants)

Start year: 2022

Summary: Disorders of compulsion, such as obsessive-compulsive disorder and substance use disorder, are chronic, debilitating, and present a significant cost to the individual and to society. Together, these disorders affect more than 10% of the population. Moreover, 40-60% of these individuals are resistant to current treatment. The current project is aimed at improving the preclinical research underlying our understanding the behavioural and brain mechanisms of such disorders and how to treat them.

Publications:

Gladding, JM, Bradfield, LA & Kendig, MD 2023, 'Diet and obesity effects on cue-driven food-seeking: insights from studies of Pavlovian-instrumental transfer in rodents and humans', Frontiers in Behavioral Neuroscience, vol. 17, p. 1199887.
View/Download from: Publisher's site

FOR Codes: Central Nervous System, Expanding Knowledge in the Biological Sciences, Central nervous system , Cognitive neuroscience

Acknowledgement of Country

UTS acknowledges the Gadigal people of the Eora Nation, the Boorooberongal people of the Dharug Nation, the Bidiagal people and the Gamaygal people, upon whose ancestral lands our university stands. We would also like to pay respect to the Elders both past and present, acknowledging them as the traditional custodians of knowledge for these lands.