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Effect of TBK1 and STING inhibitors on COVID-19 infection

Project Member(s): Hansbro, P.

Funding or Partner Organisation: Noxopharm Limited
Noxopharm Limited

Start year: 2022

Summary: This project is to investigate the anti-inflammatory potential of TBK1 and STING inhibitors in Prof. Hansbro’s mouse model of SARS-CoV-2 induced hyperinflammation, and confirm the protective activity of these inhibitors against COVID-19. The aim is to provide direct evidence with appropriate control cohorts of the anti-inflammatory effect of inhibitors in the context of SARS-CoV-2 infection, to support further clinical trials in the USA and Europe.

FOR Codes: Treatment of human diseases and conditions, Respiratory diseases