The detection of human papillomavirus 16 (HPV16) in the saliva of Head and Neck cancer patients.

Start year: 2024

Summary: This project focuses on developing a non-invasive diagnostic method for detecting human papillomavirus 16 (HPV16), a key cause of head and neck squamous cell carcinomas (HNSCC). HPV16 accounts for up to 50% of these cancers, with oral squamous cell carcinoma being one of the most common. Current detection methods, like biopsies, are invasive and challenging for early diagnosis. Our lab is creating a saliva-based multiplex quantitative PCR assay to detect viral RNA, offering a simple, cost-effective, and patient-friendly alternative. This project aims to improve early detection, guide treatment decisions, and enhance outcomes for HPV16-positive HNSCC patients.

Acknowledgement of Country

UTS acknowledges the Gadigal people of the Eora Nation, the Boorooberongal people of the Dharug Nation, the Bidiagal people and the Gamaygal people, upon whose ancestral lands our university stands. We would also like to pay respect to the Elders both past and present, acknowledging them as the traditional custodians of knowledge for these lands.