Publications

Beck, DA, Brady, BHG & Grant, DR 1997, 'Induced stress and microseismicity in the 3000 Orebody, Mount Isa', Geotechnical and Geological Engineering, vol. 15, no. 3, pp. 221-233.
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The 3000 Orebody is one of two orebodies in the Deep Copper Mine at Mount Isa, Australia. Owing to concerns about potential shaft pillar instabilities, an integrated seismic system was introduced to monitor seismic activity associated with pillar and country rock deformation. Coupled with numerical modelling of the stress regime, the system may assist in the characterization of rock mass damage resulting from mining, and perhaps the identification of near- and far-field geological structures that affect slope performance. A study was undertaken to quantify the seismicity and to determine potential applications of the seismic technology. The relation between geological structure and seismicity is strong, suggesting good prospects for the use of the system in the ground-control activities noted above. The induction of seismicity, which involves small magnitude events, is associated with reduction of normal stress on planes of weakness, suggesting that stress path may be an important factor in the level of seismicity observed in hard rock mines.

Howard, GM, Nguyen, TV, Pocock, NA, Kelly, PJ & Eisman, JA 1997, 'Influence of handedness on calcaneal ultrasound: Implications for assessment of osteoporosis and study design', OSTEOPOROSIS INTERNATIONAL, vol. 7, no. 3, pp. 190-194.
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Hutvagner, GJ, Barta, E & Banfalvi, Z 1997, 'Isolation and sequence analysis of a cDNA and a related gene for cytochrome P450 proteins from Solanum chacoense', Gene, vol. 188, no. 2, pp. 247-252.
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Inosine-containing degenerate PCR primers corresponding to the heme-binding domain of cytochrome P450 proteins have been synthesized and used for cloning cDNAs by the RT-PCR technique from Solanum chacoense. One clone in which the primer was immediately

Jahanfar, S, Eden, JA, Nguyen, T, Wang, XL & Wilcken, DEL 1997, 'A twin study of polycystic ovary syndrome and lipids', GYNECOLOGICAL ENDOCRINOLOGY, vol. 11, no. 2, pp. 111-117.
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Jung, BP, Nguyen, T, Kolakowski, LF, Lynch, KR, Heng, HHQ, George, SR & O'Dowd, BF 1997, 'Discovery of a novel human G protein-coupled receptor gene (GPR25) located on chromosome 1', Biochemical and Biophysical Research Communications, vol. 230, no. 1, pp. 69-72.
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We amplified human genomic DNA by the polymerase chain reaction (PCR) using oligonucleotides based on the primary sequence of the genes encoding the somatostatin receptors (SSTR) and the somatostatin-like receptor gene SLC-1. One resultant DNA fragment was used to screen a genomic DNA library resulting in the isolation of a gene, GPR25, encoding an additional member of the G protein-coupled receptor family (GPCR). GPR25 is intronless throughout its open reading frame (ORF) and encodes a protein of 360 amino acids. The receptor encoded by GPR25 shares highest identity to the receptor encoded by GPR15, angiotensin II type 1A receptor, and somatostatin receptor 5. Northern analysis found no transcripts expressed in liver or any of the 12 brain regions analyzed. Fluorescence in situ hybridization analysis localized GPR25 to chromosome lq32.1.

Kelly, PJ, Sambrook, PN, Morrison, NA, Nguyen, T & Eisman, JA 1997, 'Genetics of osteoporosis.', World review of nutrition and dietetics, vol. 80, pp. 126-144.

Kolakqwsk, LF, Casares, J, Marchese, A, Johnson, MP, Nguyen, T, Lynch, KR, George, SR & O'Dowd, B 1997, 'Discovery, cloning, and characterization of a novel human G protein-coupled receptor genes', FASEB Journal, vol. 11, no. 9.
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Utilizing degenerate PC'R and KST derived probes we have cloned and characterized four novel G-proteiri-coupled receptor genes termed GPR2G, GPR27, GPR28 and GPR29. Three of these new receptor °;<'nes are expressed predominantly in brain tissues. The fourth (GPR2K) is very abundantly expressed in all tissues examined. The gene for GPR26 is interrupted by one intron and both human partial cDNA and fuli length rat cDNAs have been cloned. In situ hybridization patterns show abundant expression of GPR26 in the brain with the highest levels observed in cortex and hippocampus. Both GPR26 and GPR27 show significant similarity to dopamme receptors, but are not subtypes of known catecholarnine receptor.-". GPR2S and GPR29 are more similar to chemoattractant receptors. The determination of the sequences, expression patterns and chromosome localization in both mouse and hitman may provide information needed for the identification of novel endogenous ligands for these receptors.

Lapsys, NM, Furler, SM, Moore, KR, Nguyen, TV, Herzog, H, Howard, G, Samaras, K, Carey, DG, Morrison, NA, Eisman, JA & Chisholm, DJ 1997, 'Relationship of a novel polymorphic marker near the human obese (OB) gene to fat mass in healthy women', OBESITY RESEARCH, vol. 5, no. 5, pp. 430-433.

Morrison, NA, Qi, JC, Tokita, A, Kelly, PJ, Crofts, L, Nguyen, TV, Sambrook, PN & Eisman, JA 1997, 'Correction: Prediction of bone density from vitamin D raceptor alleles', Nature, vol. 387, no. 6628, pp. 106-106.
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Morrison, NA, Qi, JC, Tokita, A, Kelly, PJ, Crofts, L, Nguyen, TV, Sambrook, PN & Elsman, JA 1997, 'Erratum: Prediction of bone density from vitamin D receptor alleles (Nature (1994) 367 (284-287))', Nature, vol. 387, no. 6628, p. 106.
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Nguyen, TV, Sambrook, PN & Eisman, JA 1997, 'Sources of variability in bone mineral density measurements: Implications for study design and analysis of bone loss', JOURNAL OF BONE AND MINERAL RESEARCH, vol. 12, no. 1, pp. 124-135.
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O'Dowd, BF, Nguyen, T, Jung, BP, Marchese, A, Cheng, R, Heng, HHQ, Kolakowski, LF, Lynch, KR & George, SR 1997, 'Cloning and chromosomal mapping of four putative novel human G-protein-coupled receptor genes', Gene, vol. 187, no. 1, pp. 75-81.
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We report the discovery of four novel human putative G-protein-coupled receptor (GPCR) genes. Gene GPR20 was isolated by amplifying genomic DNA with oligos based on the opioid and somatostatin related receptor genes and subsequent screening of a genomic library. Also, using our customized search procedure of a database of expressed sequence tags (dbEST), cDNA sequences that partially encoded novel GPCRs were identified. These cDNA fragments were obtained and used to screen a genomic library to isolate the full-length coding region of the genes. This resulted in the isolation of genes GPR21, GPR22 and GPR23. The four encoded receptors share significant identity to each other and to other members of the receptor family. Northern blot analysis revealed expression of GPR20 and GPR22 in several human brain regions while GPR20 expression was detected also in liver. Fluorescence in situ hybridization (FISH) was used to map GPR20 to chromosome 8q, region 24.3-24.2, GPR21 to chromosome 9, region q33, GPR22 to chromosome 7, region q22-q31.1, and GPR23 to chromosome X, region q13-q21.1.

Samaras, K, Spector, TD, Nguyen, TV, Baan, K, Campbell, LV & Kelly, PJ 1997, 'Independent genetic factors determine the amount and distribution of fat in women after the menopause', JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, vol. 82, no. 3, pp. 781-785.
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Sawzdargo, M, George, SR, Nguyen, T, Xu, S, Kolakowski, LF & O'dowd, BF 1997, 'A cluster of four novel human G protein-coupled receptor genes occurring in close proximity to CD22 gene on chromosome 19q13.1', Biochemical and Biophysical Research Communications, vol. 239, no. 2, pp. 543-547.
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In our search for novel human galanin receptor (GALR) subtypes, human genomic DNA was PCR amplified using sets of degenerate primers based on conserved sequences in human and rat GALR. The sequence of one of the subcloned PCR products revealed homology to a sequence in the 3' region of the human CD22 gene following a BLAST search of GenBank's database. A search for open reading frames (ORF) in the non-coding CD22 sequence resulted in identification of two novel putative intronless genes, GPR40 and GPR41. The recent submission of sequence overlapping the downstream CD22 sequence revealed a possible polymorphic insert containing a third intronless gene, GPR42, sharing 98% amino acid identity with GPR41, followed by a fourth intronless gene, GPR43. Thus, the GPR40, GPR41, GPR42, and GPR43 genes, respectively, occur downstream from CD22, a gene previously localized on chromosome 19q13.1. The four putative novel human genes encode new members of the GPCR family and share little homology with GALR.

Suzuki, H & Sanagavarapu, AM 1997, 'Ray Tube Tracing Method For Predicting Indoor Channel Characteristics Map', Electronics Letters, vol. 33, no. 17, pp. 1495-1496.
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A novel adaptive ray tube tracing algorithm optimised for creating indoor radio channel characteristic maps is presented. The algorithm, based on the shooting-and-bouncing-ray with image method and an adaptive resolution control technique, shows a large

AlJumaily, AAS, Amin, SHM & Khalil, M 1997, 'A fuzzy multi-behaviour reactive obstacle avoidance navigation for a climbing mobile robot', INES'97 : 1997 IEEE INTERNATIONAL CONFERENCE ON INTELLIGENT ENGINEERING SYSTEMS, PROCEEDINGS, 1997 IEEE International Conference on Intelligent Engineering Systems (INES 97), I E E E, BUDAPEST, HUNGARY, pp. 147-152.

Center, JR, Nguyen, TV, White, CP & Eisman, JA 1997, 'Male osteoporosis predictors: Sex hormones and calcitropic hormones.', JOURNAL OF BONE AND MINERAL RESEARCH, BLACKWELL SCIENCE INC, pp. F569-F569.

Conn, C, Gneub, D, Booth, N, Mohan, AS & Unsworth, J 1997, 'Microwave properties of polyaniline-PVC composites', SMART MATERIALS, STRUCTURES, AND INTEGRATED SYSTEMS, Conference on Smart Materials, Structures, and Integrated Systems, SPIE-INT SOC OPTICAL ENGINEERING, ADELAIDE, AUSTRALIA, pp. 156-167.
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Ensrud, K, Seeley, D, Nguyen, T, White, C, Lipschutz, R, Zmuda, J, Cauley, J, Eisman, J & Cummings, S 1997, 'Vitamin D receptor (VDR) genotype and fracture risk in older women: The study of osteoporotic fractures (SOF).', JOURNAL OF BONE AND MINERAL RESEARCH, BLACKWELL SCIENCE INC, pp. 98-98.

Howard, GM, Nguyen, TV & Eisman, JA 1997, 'Association between bone mass and body composition: Same genes or same environments?', JOURNAL OF BONE AND MINERAL RESEARCH, BLACKWELL SCIENCE INC, pp. S561-S561.

Nguyen, TV, Sambrook, PN & Eisman, JA 1997, 'Prediction of fractures by bone loss and bone mineral density: Roles of physical activity and weight loss.', JOURNAL OF BONE AND MINERAL RESEARCH, BLACKWELL SCIENCE INC, pp. 146-146.

Samaras, K, Nguyen, TV, Jenkins, AB, Kelly, PJ & Campbell, LV 1997, 'Do genes or environment explain the relationships between central fat, insulin and glucose?', DIABETOLOGIA, SPRINGER VERLAG, pp. 1018-1018.

Wang, JG & Mohan, AS 1997, 'An adaptive antenna array with parallel beamformers for indoor radio channel enhancement', 1997 IEEE 47TH VEHICULAR TECHNOLOGY CONFERENCE PROCEEDINGS, VOLS 1-3, IEEE 47th Vehicular Technology Conference - Technology in Motion (VTC 97), I E E E, PHOENIX, AZ, pp. 188-192.

Wang, JG & Mohan, AS 1997, 'Modified Weiner beamforming for indoor multipath channels', 1997 IEEE 6TH INTERNATIONAL CONFERENCE ON UNIVERSAL PERSONAL COMMUNICATIONS RECORD, CONFERENCE RECORD, VOLS 1 AND 2, 1997 IEEE 6th International Conference on Universal Personal Communications Record (ICUPC 97), I E E E, SAN DIEGO, CA, pp. 823-827.

Wang, JG & Mohan, AS 1997, 'Recombination of multipath propagation via adaptive antenna array with beamformer-RAKE structure', PROCEEDINGS OF THE FOURTH INTERNATIONAL SYMPOSIUM ON ANTENNAS AND EM THEORY (ISAE'97), 4th International Symposium on Antennas and EM Theory (ISAE 97), INT ACADEMIC PUBL, XIAN, PEOPLES R CHINA, pp. 223-224.

Weily, AR & Mohan, AS 1997, 'Mixed combline and HE11 mode dielectric resonator filter with improved spurious performance', 1997 ASIA-PACIFIC MICROWAVE CONFERENCE PROCEEDINGS, VOLS I-III, 1997 Asia Pacific Microwave Conference - Wireless Communications in the Era of Information (APMC 97), CITY UNIVERSITY HONG KONG, CITY UNIV HONG KONG, HONG KONG, PEOPLES R CHINA, pp. 805-808.