Publications

Su, SW, Anderson, B & brinsmead, TS 2001, 'Constant disturbance rejection and zero steady state tracking error for nonlinear systems design' in Biswa Datta (ed), Applied and Computational Control, Signals, and Circuits - Recent Developments, Kluwer Academic Publishers, Boston, pp. 1-30.
View description>>

S. W. Su, B. D. O. Anderson, and T. S. Brinsmead. Constant disturbance rejection and zero steady state tracking error for nonlinear systems design, In Biswa Datta, editor, Applied computational control, signals, and circuits 2001, Pages 1-30, KLUWER, BOSTON.

Bell, NH, Morrison, NA, Nguyen, TV, Eisman, J & Hollis, BW 2001, 'ApaI polymorphisms of the vitamin D receptor predict bone density of the lumbar spine and not racial difference in bone density in young men', JOURNAL OF LABORATORY AND CLINICAL MEDICINE, vol. 137, no. 2, pp. 133-140.
View/Download from: Publisher's site

Endo, MM, Barbour, PSM, Barton, DC, Fisher, J, Tipper, JL, Ingham, E & Stone, MH 2001, 'Comparative wear and wear debris under three different counterface conditions of crosslinked and non-crosslinked ultra high molecular weight polyethylene', BIO-MEDICAL MATERIALS AND ENGINEERING, vol. 11, no. 1, pp. 23-35.

Firkins, PJ, Tipper, JL, Ingham, E, Stone, MH, Farrar, R & Fisher, J 2001, 'A novel low wearing differential hardness, ceramic-on-metal hip joint prosthesis', JOURNAL OF BIOMECHANICS, vol. 34, no. 10, pp. 1291-1298.
View/Download from: Publisher's site

Firkins, PJ, Tipper, JL, Ingham, E, Stone, MH, Farrar, R & Fisher, J 2001, 'Influence of simulator kinematics on the wear of metal-on-metal hip prostheses', PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, vol. 215, no. H1, pp. 119-121.
View/Download from: Publisher's site

Firkins, PJ, Tipper, JL, Saadatzadeh, MR, Ingham, E, Stone, MH, Farrar, R & Fisher, J 2001, 'Quantitative analysis of wear and wear debris from metal-on-metal hip prostheses tested In a physiological hip joint simulator', BIO-MEDICAL MATERIALS AND ENGINEERING, vol. 11, no. 2, pp. 143-157.

Harris, M, Hauser, S, Nguyen, TV, Kelly, PJ, Rodda, C, Morton, J, Freezer, N, Strauss, BJG, Eisman, JA & Walker, JL 2001, 'Bone mineral density in prepubertal asthmatics receiving corticosteroid treatment', JOURNAL OF PAEDIATRICS AND CHILD HEALTH, vol. 37, no. 1, pp. 67-71.
View/Download from: Publisher's site

Hillman, KM, Buist, MD, Nguyen, TV, Chakraverty, S, Wright, J, Plowman, R, Roberts, JA, Graves, N, Griffin, MAS, Cookson, B, Taylor, L, Collopy, BT, Mcdonald, IG, Griffith, D, Diggory, P, Mehta, A, Vincent, C, Neale, G, Woloshynowych, M, Ferner, RE, Aronson, JK & Bezruchka, S 2001, 'Adverse events in British hospitals', BMJ, vol. 322, no. 7299, p. 1425.
View/Download from: Publisher's site

Howling, GI, Barnett, PI, Tipper, JL, Stone, MH, Fisher, J & Ingham, E 2001, 'Quantitative characterization of polyethylene debris isolated from periprosthetic tissue in early failure knee implants and early and late failure Charnley hip implants', JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, vol. 58, no. 4, pp. 415-420.
View/Download from: Publisher's site

Hutvagner, GJ, Banfalvi, Z, Milankovics, I, Silhavy, D, Polgar, Z, Horvath, S, Wolters, P & Nap, J 2001, 'Molecular markers associated with leptinine production are located on chromosome 1 in Solanum chacoense', Theoretical And Applied Genetics, vol. 102, no. 6-7, pp. 1065-1071.
View/Download from: Publisher's site
View description>>

Leptines of Solanum chacoense are effective natural deterrents against the Colorado potato beetle. Leptines are the acetylated forms of the glycoalkaloids solanine and chaconine and are supposed to be synthesised via hydroxylated derivatives, called lept

Hutvagner, GJ, Mclachlan, J, Pasquinelli, A, Balint, E, Tuschl, T & Zamore, P 2001, 'A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA', Science, vol. 293, no. 5531, pp. 834-838.
View/Download from: Publisher's site
View description>>

The 21-nucleotide small temporal RNA (stRNA) let-7 regulates developmental timing in Caenorhabditis elegans and probably in other bilateral animals. We present in vivo and in vitro evidence that in Drosophila melanogaster a developmentally regulated prec

Im, DS, Heise, CE, Nguyen, T, O'Dowd, BF & Lynch, KR 2001, 'Identification of a molecular target of psychosine and its role in globoid cell formation', Journal of Cell Biology, vol. 153, no. 2, pp. 429-434.
View/Download from: Publisher's site
View description>>

Globoid cell leukodystrophy (GLD) is characterized histopathologically by apoptosis of oligodendrocytes, progressive demyelination, and the existence of large, multinuclear (globoid) cells derived from perivascular microglia. The glycosphingolipid, psychosine (D-galactosyl-β-1,1′ sphingosine), accumulates to micromolar levels in GLD patients who lack the degradative enzyme galactosyl ceramidase. Here we document that an orphan G protein-coupled receptor, T cell death-associated gene 8, is a specific psychosine receptor. Treatment of cultured cells expressing this receptor with psychosine or structurally related glycosphingolipids results in the formation of globoid, multinuclear cells. Our discovery of a molecular target for psychosine suggests a mechanism for the globoid cell histology characteristic of GLD, provides a tool with which to explore the disjunction of mitosis and cytokinesis in cell cultures, and provides a platform for developing a medicinal chemistry for psychosine.

Johnson, AG, Nguyen, TV & Davis, D 2001, 'Blood pressure is linked to salt intake and modulated by the angiotensinogen gene in normotensive and hypertensive elderly subjects', JOURNAL OF HYPERTENSION, vol. 19, no. 6, pp. 1053-1060.
View/Download from: Publisher's site

Lee, DK, George, SR, Cheng, R, Nguyen, T, Liu, Y, Brown, M, Lynch, KR & O'Dowd, BF 2001, 'Identification of four novel human G protein-coupled receptors expressed in the brain', Molecular Brain Research, vol. 86, no. 1-2, pp. 13-22.
View/Download from: Publisher's site
View description>>

We report the discovery and tissue distributions of four novel human genes, GPR61, GPR62, GPR63 and GPR77, all of which encode G protein-coupled receptors (GPCRs). GPR61 was discovered in a search of the patent literature which retrieved a rabbit DNA sequence partially encoding a novel GPCR. This sequence was used to obtain a full-length human cDNA encoding GPR61, a receptor of 417 amino acid length. A search of the GenBank genomic sequence databases revealed three previously unrecognized intronless genes encoding the orphan GPCrs (oGPCRs) GPR62, GPR63 and GPR77, with respective amino acid lengths of 368, 419 and 337. Sequence analysis revealed that GPR61 and GPR62, and a published orphan receptor p47MNR, shared the highest level of identities to each other, ranging from 36 to 45% in the transmembrane (TM) domains. Together, these three oGPCRs appear to comprise a novel subfamily of GPCRs, most closely related to the serotonin 5-HT6 receptor. Sequence analysis of GPR63 and GPR77 revealed highest sequence identities in the TM regions with the oGPCR PSP24 (58%) and the anaphylatoxin C5a receptor (49%) respectively. Tissue distribution analyses detected the expression of all four novel genes in the human brain. GPR61 mRNA expression was detected in the caudate, putamen and thalamus of human brain, with a more widespread expression pattern in rat brain, with mRNA signals in areas of the cortex, hippocampus, thalamus, hypothalamus and midbrain. GPR62 mRNA expression was detected in the basal forebrain, frontal cortex, caudate, putamen, thalamus and hippocampus. GPR63 mRNA expression was detected in the frontal cortex, with lower levels in the thalamus, caudate, hypothalamus and midbrain. Analysis of GPR77 mRNA expression revealed signals in the frontal cortex, hippocampus and hypothalamus with high transcript levels in the liver. © 2001 Elsevier Science B.V.

Lee, DK, Nguyen, T, Lynch, KR, Cheng, R, Vanti, WB, Arkhitko, O, Lewis, T, Evans, JF, George, SR & O'Dowd, BF 2001, 'Discovery and mapping of ten novel G protein-coupled receptor genes', Gene, vol. 275, no. 1, pp. 83-91.
View/Download from: Publisher's site
View description>>

We report the identification, cloning and tissue distributions of ten novel human genes encoding G protein-coupled receptors (GPCRs) GPR78, GPR80, GPR81, GPR82, GPR93, GPR94, GPR95, GPR101, GPR102, GPR103 and a pseudogene, ψGPR79. Each novel orphan GPCR (oGPCR) gene was discovered using customized searches of the GenBank high-throughput genomic sequences database with previously known GPCR-encoding sequences. The expressed genes can now be used in assays to determine endogenous and pharmacological ligands. GPR78 shared highest identity with the oGPCR gene GPR26 (56% identity in the transmembrane (TM) regions). ψGPR79 shared highest sequence identity with the P2Y2 gene and contained a frame-shift truncating the encoded receptor in TM5, demonstrating a pseudogene. GPR80 shared highest identity with the P2Y1 gene (45% in the TM regions), while GPR81, GPR82 and GPR93 shared TM identities with the oGPCR genes HM74 (70%), GPR17 (30%) and P2Y5 (40%), respectively. Two other novel GPCR genes, GPR94 and GPR95, encoded a subfamily with the genes encoding the UDP-glucose and P2Y12 receptors (sharing >50% identities in the TM regions). GPR101 demonstrated only distant identities with other GPCR genes and GPR102 shared identities with GPR57, GPR58 and PNR (35-42% in the TM regions). GPR103 shared identities with the neuropeptide FF 2, neuropeptide Y2 and galanin GalR1 receptors (34-38% in the TM regions). Northern analyses revealed GPR78 mRNA expression in the pituitary and placenta and GPR81 expression in the pituitary. A search of the GenBank databases with the GPR82 sequence retrieved an identical sequence in an expressed sequence tag (EST) partially encoding GPR82 from human colonic tissue. The GPR93 sequence retrieved an identical, human EST sequence from human primary tonsil B-cells and an EST partially encoding mouse GPR93 from small intestinal tissue. GPR94 was expressed in the frontal cortex, caudate putamen and thalamus of brain while GPR95 was expressed in the huma...

Nguyen, T, Shapiro, DA, George, SR, Setola, V, Lee, DK, Cheng, R, Rauser, L, Lee, SP, Lynch, KR, Roth, BL & O'Dowd, BF 2001, 'Discovery of a novel member of the histamine receptor family', Molecular Pharmacology, vol. 59, no. 3, pp. 427-433.
View/Download from: Publisher's site
View description>>

We report the discovery, tissue distribution and pharmacological characterization of a novel receptor, which we have named H4. Like the three histamine receptors reported previously (H1, H2, and H3), the H4 receptor is a G protein-coupled receptor and is most closely related to the H3 receptor, sharing 58% identity in the transmembrane regions. The gene encoding the H4 receptor was discovered initially in a search of the GenBank databases as sequence fragments retrieved in a partially sequenced human genomic contig mapped to chromosome 18. These sequences were used to retrieve a partial cDNA clone and, in combination with genomic fragments, were used to determine the full-length open reading frame of 390 amino acids. Northern analysis revealed a 3.0-kb transcript in rat testis and intestine. Radioligand binding studies indicated that the H4 receptor has a unique pharmacology and binds [3H]histamine (Kd = 44 nM) and [3H]pyrilamine(Kd = 32 nM) and several psychoactive compounds (amitriptyline, chlorpromazine, cyproheptadine, mianserin) with moderate affinity (Ki range of 33-750 nM). Additionally, histamine induced a rapid internalization of HA-tagged H4 receptors in transfected human embryonic kidney 293 cells.

Nguyen, TT, Taylor, PWJ, Brouwer, JB, Pang, ECK & Ford, R 2001, 'A novel source of resistance in lentil (Lens culinaris ssp culinaris) to ascochyta blight caused by Ascochyta lentis', AUSTRALASIAN PLANT PATHOLOGY, vol. 30, no. 3, pp. 211-215.
View/Download from: Publisher's site

Nguyen, TV & Hillman, KM 2001, 'On the analysis and interpretation of spontaneous variability of cardiac output', CRITICAL CARE MEDICINE, vol. 29, no. 1, pp. 220-221.
View/Download from: Publisher's site

Nguyen, TV & Sambrook, PN 2001, 'Clinical role of quantitative ultrasound in the assessment of osteoporosis in individual patients', MEDICAL JOURNAL OF AUSTRALIA, vol. 174, no. 6, pp. 310-311.
View/Download from: Publisher's site

Nguyen, TV & Wong, FW 2001, 'The effects of Chinese medicinal herbs on postmenopausal vasomotor symptoms of Australian women', MEDICAL JOURNAL OF AUSTRALIA, vol. 175, no. 4, pp. 230-230.
View/Download from: Publisher's site

Nguyen, TV, Center, JR, Sambrook, PN & Eisman, JA 2001, 'Risk factors for proximal humerus, forearm, and wrist fractures in elderly men and women - The Dubbo osteoporosis epidemiology study', AMERICAN JOURNAL OF EPIDEMIOLOGY, vol. 153, no. 6, pp. 587-595.
View/Download from: Publisher's site

Nguyen, TV, Hillman, KM & Buist, MD 2001, 'Adverse events in British hospitals - Preventive strategies, not epidemiological studies, are needed', BRITISH MEDICAL JOURNAL, vol. 322, no. 7299, pp. 1425-1425.
View/Download from: Publisher's site

Nguyen, TV, Hillman, KM, Buist, MD, Chakraverty, S, Wright, J, Plowman, R, Roberts, JA, Graves, N, Griffin, MAS, Cookson, B, Taylor, L, Collopy, BT, McDonald, IG, Griffith, D, Diggory, P, Mehta, A, Vincent, C, Neale, G, Woloshynowych, M, Ferner, RE, Aronson, JK & Bezruchka, S 2001, 'Adverse events in British hospitals [2] (multiple letters)', British Medical Journal, vol. 322, no. 7299, pp. 1425-1427.

Nguyen, TV, Maynard, LM, Towne, B, Roche, AF, Wisemandle, W, Li, JR, Guo, SMS, Chumlea, WC & Siervogel, RM 2001, 'Sex differences in bone mass acquisition during growth', JOURNAL OF CLINICAL DENSITOMETRY, vol. 4, no. 2, pp. 147-157.
View/Download from: Publisher's site

Tipper, JL, Firkins, PJ, Besong, AA, Barbour, PSM, Nevelos, J, Stone, MH, Ingham, E & Fisher, J 2001, 'Characterisation of wear debris from UHMWPE on zirconia ceramic, metal-on-metal and alumina ceramic-on-ceramic hip prostheses generated in a physiological anatomical hip joint simulator', WEAR, vol. 250, pp. 120-128.
View/Download from: Publisher's site

Torjek, O, Kiss, E, Mazik-tokei, K, Hutvagner, GJ, Silhavy, D, Banfalvi, Z, Kertesz, Z, Pauk, J & Heszky, L 2001, 'Comparative molecular analysis of winter wheat cultivars and their doubled haploid derivatives', Cereal Research Communications, vol. 29, no. 1-2, pp. 41-48.
View description>>

Genetic stability of doubled haploid (DH) lines of androgenetic origin is the prerequisite of their breeding value. In our investigations GK Gobe: a traditional cultivar, GK Delibab: a cultivar of doubled haploid origin, various DH lines of GK Gobe (firs

Weily, AR & Sanagavarapu, AM 2001, 'Microwave Filters', Microwave and Optical Technology Letters, vol. 29, no. 1, pp. 6-11.
View/Download from: Publisher's site

Weily, AR & Sanagavarapu, AM 2001, 'Microwave Filters With Improved Spurious Performance Based on Sandwiched Conductor Dielectric Resonators', IEEE Transactions on Microwave Theory and Techniques, vol. 49, no. 8, pp. 1501-1507.
View/Download from: Publisher's site
View description>>

Microwave filters based on a novel resonator comprised of a sandwiched conductor dielectric resonator (SCDR) loaded in a cylindrical cavity are analyzed in this paper. The SCDR is a compact resonator that exhibits good spurious performance. Resonant frequencies of the lower order modes are analyzed, and mode charts, unloaded , slot coupling, and screw coupling graphs are presented. -parameters are computed using the finite- difference time-domain (FDTD) method for one- and four-pole SCDR filters and compared with measured results. The measured spurious performance for the four-pole elliptic function filter shows a large improvement over conventional dielectric-resonator filters. The measured results agree closely with predicted values obtained using the FDTD method

Zhang, Y, Hu, Y & Su, S 2001, 'A robust guidance algorithm design using variable structure control', Xi Tong Gong Cheng Yu Dian Zi Ji Shu/Systems Engineering and Electronics, vol. 23, no. 4, pp. 61-63.
View description>>

For the case of planar interception, the so called relative heading error angle between the relative velocity vector and the LoS (Line of Sight) is chosen as the output to be controlled to zero. The terms related to the acceleration and velocity heading angle of target are regarded as disturbances, a robust guidance algorithm design is given by using the theory of variable structure control. The proposed guidance algorithm needs no accurate information on the acceleration and velocity heading angle of the target, and hence is more convenient for practical implementation. The simulation results show that the algorithm has strong robustness to the maneuvering of the target.

Zozulya, S, Echeverri, F & Nguyen, T 2001, 'The human olfactory receptor repertoire.', Genome biology, vol. 2, no. 6.
View description>>

BACKGROUND: The mammalian olfactory apparatus is able to recognize and distinguish thousands of structurally diverse volatile chemicals. This chemosensory function is mediated by a very large family of seven-transmembrane olfactory (odorant) receptors encoded by approximately 1,000 genes, the majority of which are believed to be pseudogenes in humans. RESULTS: The strategy of our sequence database mining for full-length, functional candidate odorant receptor genes was based on the high overall sequence similarity and presence of a number of conserved sequence motifs in all known mammalian odorant receptors as well as the absence of introns in their coding sequences. We report here the identification and physical cloning of 347 putative human full-length odorant receptor genes. Comparative sequence analysis of the predicted gene products allowed us to identify and define a number of consensus sequence motifs and structural features of this vast family of receptors. A new nomenclature for human odorant receptors based on their chromosomal localization and phylogenetic analysis is proposed. We believe that these sequences represent the essentially complete repertoire of functional human odorant receptors. CONCLUSIONS: The identification and cloning of all functional human odorant receptor genes is an important initial step in understanding receptor-ligand specificity and combinatorial encoding of odorant stimuli in human olfaction.

Bell, J, Tipper, JL, Ingham, E, Stone, MH & Fisher, J 2001, 'The influence of phospholipid concentration in protein-containing lubricants on the wear of ultra-high molecular weight polyethylene in artificial hip joints', PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, SAGE PUBLICATIONS LTD, pp. 259-263.
View/Download from: Publisher's site

Buist, M, Moore, G, Bernard, S, Waxman, B, Anderson, J & Nguyen, T 2001, 'The effect of the medical emergency team in the reduction of the incidence and mortality from unexpected in hospital cardiac arrest', CRITICAL CARE MEDICINE, LIPPINCOTT WILLIAMS & WILKINS, pp. A174-A174.

Center, JR, Nguyen, TV, Henderson, NK, Pocock, NA & Eisman, JA 2001, 'Volumetric bone density and fracture risk in men and women in the Dubbo Osteoporosis Epidemiology Study (DOES).', JOURNAL OF BONE AND MINERAL RESEARCH, AMER SOC BONE & MINERAL RES, pp. S390-S390.

Chung, KL & Mohan, AS 2001, 'Novel singly-fed rectangular microstrip patch elements for circular polarisation', APMC 2001: ASIA-PACIFIC MICROWAVE CONFERENCE, VOLS 1-3, PROCEEDINGS, Asia/Pacific Microwave Conference, IEEE, TAIPEI, TAIWAN, pp. 1334-1337.

Eisman, JA, Taneri, B, Nguyen, TV & Ott, J 2001, 'Linkage in extended pedigree studies of bone phenotypes.', JOURNAL OF BONE AND MINERAL RESEARCH, AMER SOC BONE & MINERAL RES, pp. S351-S351.

Fisher, J, Bell, J, Barbour, PSM, Tipper, JL, Matthews, JB, Besong, AA, Stone, MH & Ingham, E 2001, 'A novel method for the prediction of functional biological activity of polyethylene wear debris', PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, SAGE PUBLICATIONS LTD, pp. 127-132.
View/Download from: Publisher's site

Lam, HK, Ling, SH, Leung, FHF & Tam, PKS 2001, 'Optimal and stable fuzzy controllers for nonlinear systems subject to parameter uncertainties using genetic algorithm', 10TH IEEE INTERNATIONAL CONFERENCE ON FUZZY SYSTEMS, VOLS 1-3, 10th IEEE International Conference on Fuzzy Systems, IEEE, UNIV MELBOURNE, MELBOURNE, AUSTRALIA, pp. 908-911.

Lam, HK, Ling, SH, Leung, FHF & Tam, PKS 2001, 'Tuning of the structure and parameters of neural network using an improved genetic algorithm', IECON'01: 27TH ANNUAL CONFERENCE OF THE IEEE INDUSTRIAL ELECTRONICS SOCIETY, VOLS 1-3, 27th Annual Conference of the IEEE Industrial-Electronics-Society, IEEE, DENVER, CO, pp. 25-30.

Lam, HK, Ling, SH, Leung, KF & Leung, FHF 2001, 'On interpretation of graffiti commands for eBooks using a neural network and an improved genetic algorithm', 10TH IEEE INTERNATIONAL CONFERENCE ON FUZZY SYSTEMS, VOLS 1-3, 10th IEEE International Conference on Fuzzy Systems, IEEE, UNIV MELBOURNE, MELBOURNE, AUSTRALIA, pp. 1464-1467.

Ling, SH, Lam, HK, Leung, FHF & Tam, PKS 2001, 'A neural fuzzy network with optimal number of rules for short-term load forecasting in an intelligent home', 10TH IEEE INTERNATIONAL CONFERENCE ON FUZZY SYSTEMS, VOLS 1-3, 10th IEEE International Conference on Fuzzy Systems, IEEE, UNIV MELBOURNE, MELBOURNE, AUSTRALIA, pp. 1456-1459.

Ling, SH, Leung, FHF & Tam, PKS 2001, 'Daily load forecasting with a fuzzy-input-neural network in an intelligent home', 10TH IEEE INTERNATIONAL CONFERENCE ON FUZZY SYSTEMS, VOLS 1-3, 10th IEEE International Conference on Fuzzy Systems, IEEE, UNIV MELBOURNE, MELBOURNE, AUSTRALIA, pp. 449-452.

Sanagavarapu, AM, Guy, DJ, Thomas, SP & Ross, D 2000, 'Miniaturised Antennas for Microwave Ablation for the cure of Cardiac Arrhythmias', Proceedings of 2000 Asia Pacific Microwave Conference (APMC), Asia-Pacific Microwave Conference, IEEE Press, Sydney, Australia, pp. 50-53.

Stewart, T, Tipper, J, Streicher, R, Ingham, E & Fisher, J 2001, 'Long-term wear of HIPed alumina on alumina bearings for THR under microseparation conditions', JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 16th Conference of the European-Society-for-Biomaterials, SPRINGER, LONDON, ENGLAND, pp. 1053-1056.
View/Download from: Publisher's site

Su, SW 2001, 'Robust disturbance rejection for landing an autonomous vehicle', Australian East Coast Conference on Signals, Networks and Systems, ANU, Canberra, Australia.

Su, SW, Anderson, B & brinsmead, TS 2001, 'Constant disturbance suppression for nonlinear systems design using singular perturbation theory', the 40th IEEE Conference on Decision and Control, IEEE, Orlando, USA, pp. 3272-3277.