Bailey, PE & Henry, JD 2007, 'Alexithymia, somatization and negative affect in a community sample', Psychiatry Research, vol. 150, no. 1, pp. 13-20.
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Bakker, EWP, Verhagen, AP, Lucas, C, Koning, HJCMF & Koes, BW 2007, 'Spinal mechanical load: a predictor of persistent low back pain? A prospective cohort study', European Spine Journal, vol. 16, no. 7, pp. 933-941.
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Bakker, EWP, Verhagen, AP, Lucas, C, Koning, HJCMF, de Haan, RJ & Koes, BW 2007, 'Daily spinal mechanical loading as a risk factor for acute non-specific low back pain: a case–control study using the 24-Hour Schedule', European Spine Journal, vol. 16, no. 1, pp. 107-113.
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Balandin, S, Hemsley, B, Sigafoos, J & Green, V 2007, 'Communicating with nurses: The experiences of 10 adults with cerebral palsy and complex communication needs', Applied Nursing Research, vol. 20, no. 2, pp. 56-62.
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Berle, D 2007, 'Graded Exposure Therapy for Long-Standing Disgust-Related Cockroach Avoidance in an Older Male', Clinical Case Studies, vol. 6, no. 4, pp. 339-347.
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This case study outlines the use of graded in-vivo exposure to reduce an aversion to cockroaches in an older male. Following assessment, seven therapy sessions of in-vivo exposure were conducted where the client was progressively brought into closer and closer contact with cockroaches. A decrease in the client's aversion to cockroaches was apparent at posttreatment and persisted to 5-month follow-up, as evidenced by client reports and decreased behavioral avoidance. The client maintained that his avoidance had been driven by disgust, rather than fear, and the reduction of his avoidance of and aversion to cockroaches indicates that approaches developed for fearful clients may also be effective for clients who do not report fear responses to their avoided stimuli.
Berle, D & Starcevic, V 2007, 'Inconsistencies between reported test statistics and p‐values in two psychiatry journals', International Journal of Methods in Psychiatric Research, vol. 16, no. 4, pp. 202-207.
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AbstractA recent survey of the British Medical Journal (BMJ) and Nature revealed that inconsistencies in reported statistics were common. We sought to replicate that survey in the psychiatry literature. We checked the consistency of reported t‐test, F‐test and χ2‐test values with their corresponding p‐values in the 2005 issues of the Australian and New Zealand Journal of Psychiatry (ANZJP) and compared this with the issues of the ANZJP from 2000, and with a similar journal, Acta Psychiatrica Scandinavica (APS). A reported p‐value was ‘inconsistent’ if it differed (at its reported number of decimal places) from our calculated p‐values (using three different software packages), which we based on the reported test statistic and degrees of freedom. Of the 546 results that we checked, 78 (14.3%) of the p‐values were inconsistent with the corresponding degrees of freedom and test statistic. Similar rates of inconsistency were found in APS and ANZJP, and when comparing the ANZJP between 2000 and 2005. The percentages of articles with at least one inconsistency were 8.5% for ANZJP 2005, 9.9% for ANZJP 2000 and 12.1% for APS. We conclude that inconsistencies in p‐values are common and may reflect errors of analysis and rounding, typographic errors or typesetting errors. Suggestions for reducing the occurrence of such inconsistencies are provided. Copyright © 2008 John Wiley & Sons, Ltd.
Brouwer, RW, van Raaij, TM, Bierma-Zeinstra, SMA, Verhagen, AP, Jakma, TTSC & Verhaar, JAN 2007, 'Osteotomy for treating knee osteoarthritis', COCHRANE DATABASE OF SYSTEMATIC REVIEWS, no. 3.
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Chauhan, A, Siddall, V, Wilcock, A, Mallawathantri, S, Baldwin, DR & Johnston, ID 2007, 'NICE guidance for screening for malnutrition: implications for lung cancer services', Thorax, vol. 62, no. 9, pp. 835-835.
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Chauhan, A, Siddall, V, Wilcock, A, Mallawathantri, S, Baldwin, DR & Johnston, ID 2007, 'NICE guidance for screening for malnutrition: implications for lung cancer services.', Thorax, vol. 62, no. 9, p. 835.
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Cooke, GM & Beheregaray, LB 2007, 'Extremely high variability in the S72 intron of the Amazonian cardinal tetra (Paracheirodon axelrodi)', Journal of Fish Biology, vol. 71, no. sa, pp. 132-140.
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Here, a combination of a DNA screening technique, direct sequencing and cloning was used to carry out a large‐scale assessment of intron variability in cardinal tetras – the first to be conducted for an Amazonian forest fish. To the best of the authors’ knowledge, the levels of DNA variability reported in this study are the highest ever documented for an intron marker.
Feleus, A, Bierma-Zeinstra, SMA, Miedema, HS, Verhagen, AP, Nauta, AP, Burdorf, A, Verhaar, JAN & Koes, BW 2007, 'Prognostic indicators for non-recovery of non-traumatic complaints at arm, neck and shoulder in general practice—6 months follow-up', Rheumatology, vol. 46, no. 1, pp. 169-176.
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Gerdemann, A, Griese, N & Schulz, M 2007, 'Pharmacy interns on the ward—a pilot study', Pharmacy World & Science, vol. 29, no. 1, pp. 34-38.
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Hammerlein, A, Griese, N & Schulz, M 2007, 'Survey of Drug-Related Problems Identified by Community Pharmacies', Annals of Pharmacotherapy, vol. 41, no. 11, pp. 1825-1832.
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Hemsley, B, Balandin, S & Togher, L 2007, 'Older Unpaid Carers’ Experiences Supporting Adults with Cerebral Palsy and Complex Communication Needs in Hospital', Journal of Developmental and Physical Disabilities, vol. 19, no. 2, pp. 115-124.
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Huisstede, BMA, Miedema, HS, Verhagen, AP, Koes, BW & Verhaar, JAN 2007, 'Multidisciplinary consensus on the terminology and classification of complaints of the arm, neck and/or shoulder', Occupational and Environmental Medicine, vol. 64, no. 5, pp. 313-319.
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Jacobs, C, Rawson, R, Campion, C, Caulfield, C, Heath, J, Burton, C & Kavalier, F 2007, 'Providing a community-based cancer risk assessment service for a socially and ethnically diverse population', Familial Cancer, vol. 6, no. 2, pp. 189-195.
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Karels, CH, Bierma-Zeinstra, SMA, Burdorf, A, Verhagen, AP, Nauta, AP & Koes, BW 2007, 'Social and psychological factors influenced the course of arm, neck and shoulder complaints', Journal of Clinical Epidemiology, vol. 60, no. 8, pp. 839-848.
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Krochmalik, A, Jones, MK & Menzies, RG 2007, 'The Acquisition of Washing Behaviours in Obsessive–Compulsive Disorder (OCD)', Behaviour Change, vol. 24, no. 4, pp. 219-230.
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AbstractPrior to CBT treatment, nineteen obsessive–compulsive washers were administered Jones and Menzies's (1998a) obsessive–compulsive disorder (OCD) Origins Questionnaire (OOQ) in an attempt to examine the relevance of associative learning pathways in the aetiology of the disorder. The open-ended nature of the questions allows for the distinction between classical conditioning events and traumatic events in which no identifiable unconditioned stimulus can be found. On the basis of subjects' responses on the OOQ, associative learning was shown to account for only five cases of OC washing. Of note, depression was shown to facilitate the onset of OCD in these individuals. Every subject who experienced a relevant indirect learning event and went on to develop OCD, revealed they were experiencing depression at the time. No relationship was found between the mode of OCD acquisition and subsequent response to treatment. Finally, the data revealed that subjects who identified washing/cleaning concerns at the onset of their disorder, as distinct from subjects who identified other OC concerns (e.g. checking, hoarding) at the onset of their disorder, scored similarly on current level of severity and degree of intractability.
Luijsterburg, PAJ, Lamers, LM, Verhagen, AP, Ostelo, RWJG, van den Hoogen, HJMM, Peul, WC, Avezaat, CJJ & Koes, BW 2007, 'Cost-Effectiveness of Physical Therapy and General Practitioner Care for Sciatica', Spine, vol. 32, no. 18, pp. 1942-1948.
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Luijsterburg, PAJ, Verhagen, AP, Ostelo, RWJG, van Os, TAG, Peul, WC & Koes, BW 2007, 'Effectiveness of conservative treatments for the lumbosacral radicular syndrome: a systematic review', European Spine Journal, vol. 16, no. 7, pp. 881-899.
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Negrini, S & Romano, M 2007, 'On “Effect of Bracing…” Lenssinck et al. Phys Ther. 2005;85:1329–1339', Physical Therapy, vol. 87, no. 1, pp. 112-112.
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Onslow, M & Yaruss, JS 2007, 'Differing Perspectives on What to Do With a Stuttering Preschooler and Why', American Journal of Speech-Language Pathology, vol. 16, no. 1, pp. 65-68.
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Purpose In order to produce a compact and readable review of clinical issues for clinicians, the authors developed a “1,000-bites” format in which they discuss a topic initiated by one of the authors. Method The format is designed to give the reader the feeling of contemporaneous observation of a conversation between 2 authors. To that end, the format guidelines are as follows: (a) alternating responses from the authors with no response greater than 100 words; (b) a maximum of 1,000 words per author; (c) when one author has used 1,000 words, the other can complete 1,000 words in a final response or opt to not issue a final response; (d) debate may be controversial and vigorous but must be collegial; and (e) a noncontemporaneous edit by an author to a response requires the agreement of the other author. Conclusions The “1,000-bites” format achieved a collegial exchange between 2 discussants with differing opinions by creating a single work of shared authorship by them. Arguably, this format is more informative to clinicians than independent essays and rebuttals in a sequence of letters to the editor. One of its advantages is that it provides insights into the issue at stake by means of short and contemporaneous segments of spontaneous interaction.
Onslow, M, Packman, A & Gordon, PA 2007, 'Clinical identification of early stuttering: Methods, issues, and future directions', Specialusis Ugdymas/Special Education: Baltic Journal of Special Education, vol. 2, no. 17, pp. 92-106.
Onslow, M, Packman, A & Payne, PA 2007, 'Clinical Identification of Early Stuttering: Methods, Issues, and Future Directions', Asia Pacific Journal of Speech, Language and Hearing, vol. 10, no. 1, pp. 15-31.
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Packman, A, Code, C & Onslow, M 2007, 'On the cause of stuttering: Integrating theory with brain and behavioral research', Journal of Neurolinguistics, vol. 20, no. 5, pp. 353-362.
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Stuttering is present in all cultures with a prevalence of around 1%. While there has been extensive brain and behavioral research into stuttering over the last 50 years, its cause remains unknown. Brain imaging research has shown anomalous activations during stuttered speech and, more recently, has identified structural anomalies in the speech language areas of the brain. A recent meta-analysis concluded that these aberrant neural activations are a consequence of stuttering rather than a cause, and that stuttering is a disorder of the initiation of speech motor plans. Expanding on this hypothesis we propose that this disorder comprises the initiation of syllables. We provide evidence that this is underpinned by a disturbance of neural function in SMA. Our syllable initiation (SI) theory has evolved from our working model, the variability or Vmodel. SI theory draws not only on brain research in stuttering but also on research into speech production deficits after brain damage. SI theory locates stuttering at the interface of speech and language and we suggest that it provides a plausible and parsimonious explanation of the cause and critical phenomena of stuttering. © 2006 Elsevier Ltd. All rights reserved.
Packman, A, Onslow, M, O'Brian, S & Hewat, S 2007, 'Down memory lane with James and time-out', Disability and Rehabilitation, vol. 29, no. 13, pp. 1061-1065.
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Palmer, S & Kneebone, I 2007, 'An investigation of day hospital outcome measures', International Journal of Therapy and Rehabilitation, vol. 14, no. 8, pp. 372-377.
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It is important to evaluate services in order to establish best practice, allocate limited resources, and strive towards clinical excellence. This study explored outcome measures for medical rehabilitation day hospitals for older people, where a broad range of needs are addressed. The aim was to identify alternatives to the current measure in use across four day hospitals, as it was considered by staff that this measure was not consistently reflecting observed and clinically significant changes. Consultation with day hospital staff clarified the outcomes they hoped to capture in a measure, nd their concerns about current measures. Literature review identified potential alternatives, one of which was piloted; the CANE-S (Camberwell Assessment of Need-Short Form). The CANE-S was selected for pilot owing to it being specifically designed for use within services for older people, with established reliability and validity. Pilot results indicated that the CANE-S was not a suitable measure for all of the four day hospitals because it did not offer the brevity and distinctiveness required by all. Recommendations for further evaluation are discussed.
Rogers, KD, Thompson, MB & Seebacher, F 2007, 'Beneficial acclimation: sex specific thermal acclimation of metabolic capacity in the striped marsh frog (Limnodynastes peronii)', Journal of Experimental Biology, vol. 210, no. 16, pp. 2932-2938.
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SUMMARYReproductive success in thermally varying environments will depend on maintaining metabolic capacity of tissues that are important in mating behaviours. Here we test the hypothesis that cold acclimation will occur in those tissues that are important for reproduction, and that acclimation will be sex specific, reflecting behavioural differences between the sexes. We used the frog Limnodynastes peronii as a model because anurans engage in energetically demanding reproductive behaviour, and many species, including L. peronii, are reproductively active across seasons. Additionally,reproductive behaviours such as calling and amplexus are sex specific. We acclimated animals to naturally occurring autumn (15°C, N=10) and summer (25°C, N=10) temperatures. Whole-animal resting oxygen consumption decreased with lowered temperature, but there was no difference in oxygen consumption between acclimation treatments or sexes. However, the respiratory control ratio (RCR) of mitochondria from the liver and external oblique calling muscle increased with cold acclimation. The increase in RCR with thermal acclimation was due to upregulation of state 3 respiration, and not to a decrease in state 4 respiration. Males had higher activity of citrate synthase, β-hydroxyacyl CoA dehydrogenase and cytochrome coxidase than females in the calling (external oblique) muscle, and males also showed thermal acclimation of these enzymes while females did not. Additionally, males had greater activity of metabolic enzymes in the principal muscle (extensor carpi radialis) used during amplexus. However, there were no differences in metabolic capacity between sexes in the gastrocnemius muscle and in liver, and both sexes showed significant acclimation of lactate dehydrogenase and cytochrome c oxidase in the former and latter,respectively. In L. peronii, thermal acclimation of metabolic capacities is linked to reproductive success, and reversible phenoty...
Rousseau, I, Packman, A, Onslow, M, Harrison, E & Jones, M 2007, 'An investigation of language and phonological development and the responsiveness of preschool age children to the Lidcombe Program', Journal of Communication Disorders, vol. 40, no. 5, pp. 382-397.
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Knowledge of variables that predict treatment time is of benefit in deciding when to start treatment for early stuttering. To date, the only variable clearly related to treatment time with the Lidcombe Program is pre-treatment stuttering frequency. Previous studies have shown that children whose stuttering is more severe take longer to complete Stage 1 of the program. However, studies to date have not investigated phonology and language as predictors of treatment time. In the context of a Phase II clinical trial, the present prospective study showed that phonological development does not predict treatment time but that, together, stuttering severity, MLU and CELF Receptive Score predict 35-45% of the variance for time taken to complete Stage 1. Learning outcomes: The reader should be able to (1) understand guidelines developed for the timing of intervention with the Lidcombe Program based on previous retrospective studies, (2) determine whether pre-treatment language and phonological development play a role in treatment-led recovery with the Lidcombe Program and (3) understand recent empirical evidence on time taken by preschool children to complete Stage 1 of the Lidcombe Program. © 2006 Elsevier Inc. All rights reserved.
Schellingerhout, JM, Thomas, S & Verhagen, AP 2007, '[Aspecific shoulder complaints: literature review to assess the efficacy of current interventions].', Ned Tijdschr Geneeskd, vol. 151, no. 52, pp. 2892-2897.
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OBJECTIVE: To assess the efficacy of current interventions for shoulder complaints in adults. DESIGN: Systematic literature review. METHOD: Medline and the Cochrane Library were searched for systematic reviews and randomised studies on the efficacy of interventions for shoulder complaints in adults. Studies of patients with an identifiable cause of shoulder symptoms or an underlying disease were excluded. Studies evaluating pain, function and duration of symptoms were included. RESULTS: Of the III randomised clinical trials found, only a few (19) focused on aspecific shoulder complaints; the remainder involved poorly defined subgroups. II useful studies were identified. There was little or no evidence to support or refute the efficacy of NSAIDs, exercise therapy, manipulative therapy, corticosteroid injection and acupuncture in comparison to placebo for the treatment of shoulder complaints. Moderate evidence was found to support the efficacy of NSAIDs, exercise therapy, manipulative therapy, corticosteroid injection and acupuncture in head-to-head comparisons with one another. These effects were not clinically relevant. The effect of adjuvant ultrasound therapy was comparable to that of placebo. CONCLUSION: The available evidence indicates that the efficacy of interventions commonly used in The Netherlands for shoulder complaints is low, and the positive evidence available suggests a clinically irrelevant effect.
Sercombe, JK, Liu-Brennan, D, Causer, SM & Tovey, ER 2007, 'The vertical distribution of house dust mite allergen in carpet and the effect of dry vacuum cleaning', International Journal of Hygiene and Environmental Health, vol. 210, no. 1, pp. 43-50.
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Sollom, AC & Kneebone, II 2007, 'Treatment of depression in people who have multiple sclerosis', Multiple Sclerosis Journal, vol. 13, no. 5, pp. 632-635.
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Depression is common among people with multiple sclerosis (MS). Research suggests that treatments for depression are effective in this population, though few patients appear to access these treatments. Our objectives were to consider whether persons with MS and significant depressive symptoms, prompted to seek treatment by letter, did so, what professionals they consulted, and the benefits of any treatment obtained. A total of 495 individuals with MS (401 female; 94 male), aged 22-65 years (mean: 45.8 years), were surveyed in three phases at yearly intervals. Significant depressive symptoms were found over the three phases (50-60.2%). Despite a high prevalence of depressive symptoms, few participants sought treatment, even though prompted to do so. Where treatment was sought, general practitioners remained the principal group consulted. Contrary to previous reports of the efficacy of treatment in clinical trials, no strong support for this was found. Future research needs to consider why the majority of people with MS do not seek treatment for depression, and why interventions, which are not clinical trials, seem to lack effectiveness. Multiple Sclerosis 2007; 13: 632-635. http://msj.sagepub.com
Starcevic, V, Berle, D, Milicevic, D, Hannan, A, Lamplugh, C & Eslick, GD 2007, 'Pathological worry, anxiety disorders and the impact of co-occurrence with depressive and other anxiety disorders', Journal of Anxiety Disorders, vol. 21, no. 8, pp. 1016-1027.
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Starcevic, V, Latas, M, Kolar, D & Berle, D 2007, 'Are there gender differences in catastrophic appraisals in panic disorder with agoraphobia?', Depression and Anxiety, vol. 24, no. 8, pp. 545-552.
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Taş, Ü, Verhagen, AP, Bierma-Zeinstra, SMA, Hofman, A, Odding, E, Pols, HAP & Koes, BW 2007, 'Incidence and risk factors of disability in the elderly: The Rotterdam Study', Preventive Medicine, vol. 44, no. 3, pp. 272-278.
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Tas, U, Verhagen, AP, Bierma-Zeinstra, SMA, Odding, E & Koes, BW 2007, 'Prognostic factors of disability in older people: a systematic review.', Br J Gen Pract, vol. 57, no. 537, pp. 319-323.
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AIM: To systematically review the evidence on the influence of sociodemographic, lifestyle, and (bio)medical variables on the course of prevalent disability and transition rates to different outcome categories in community-dwelling older people. METHOD: Articles were identified through searches of PubMed, EMBASE, and PsycINFO databases and reference lists of relevant articles. Prospective population studies that assessed disability at baseline and reported on associations between potential prognostic variables and disability were included. Methodological quality of studies was assessed by standardised criteria, after which relevant data were extracted. A synthesis of the available evidence was carried out. RESULTS: Nine cohort studies reported transition rates and eight cohort studies presented multivariate analyses on prognostic factors. There was some heterogeneity among studies in definition and assessment of disability. There is moderate to strong evidence that higher age, cognitive impairment, vision impairment, and poor self-rated health are prognostic factors of disability. CONCLUSION: Prognostic factors, partly modifiable, are identified that should be taken into account in targeting treatment and care for older people with disabilities. Further conceptual and methodological standardisation is required in order to enable a meta-analysis and obtain higher levels of evidence.
Van Der Wouden, H, Blankenstein, N, Huibers, M, Van Der Windt, D, Stalman, W & Verhagen, A 2007, 'The Lasagna's law: Difficulties in recruiting patients for clinical trials in general practice', Huisarts en Wetenschap, vol. 50, no. 13, pp. 650-655.
van der Wouden, JC & Verhagen, AP 2007, 'Breathing techniques in the management of asthma', THORAX, vol. 62, no. 9, pp. 835-835.
van der Wouden, JC, Blankenstein, AH, Huibers, MJH, van der Windt, DAWM, Stalman, WAB & Verhagen, AP 2007, 'Survey among 78 studies showed that Lasagna's law holds in Dutch primary care research', Journal of Clinical Epidemiology, vol. 60, no. 8, pp. 819-824.
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Veale, EL, Buswell, R, Clarke, CE & Mathie, A 2007, 'Identification of a region in the TASK3 two pore domain potassium channel that is critical for its blockade by methanandamide', British Journal of Pharmacology, vol. 152, no. 5, pp. 778-786.
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Background and purpose:The TASK subfamily of two pore domain potassium channels (K2P) encodes for leak K currents, contributing to the resting membrane potential of many neurons and regulating their excitability. TASK1 and TASK3 channels are regulated by a number of pharmacological and physiological mediators including cannabinoids such as methanandamide. In this study, we investigate how methanandamide blocks these channels.Experimental approach:Currents through wild type and mutated TASK1 and TASK3 channels expressed in modified HEK‐293 cells were measured using whole‐cell electrophysiological recordings in the presence and absence of methanandamide.Key results:Methanandamide (3 μM) produced substantial block of hTASK1, hTASK3 and mTASK3 channels but was most potent at blocking hTASK3 channels. Block of these channels was irreversible unless cells were washed with buffer containing bovine serum albumin. Mutation of the distal six amino acids of TASK1 did not alter methanandamide inhibition, whilst C terminal truncation of TASK3 channels caused a small but significant reduction of inhibition. However, deletion of six amino acids (VLRFLT) at the interface between the final transmembrane domain and cytoplasmic C terminus of TASK3 channels gave functional currents that were no longer inhibited by methanandamide or by activation of GPCRs.Conclusions and implications:Methanandamide potently blocked TASK3 and TASK1 channels and both methanandamide and G protein‐mediated inhibition converged on the same intracellular gating pathway. Physiologically, methanandamide block of TASK1 and TASK3 channels may underpin a number of CNS effects of cannabinoids that are not mediated through activation of CB1
Verhagen, AP, Bierma-Zeinstra, SMA, Boers, M, Cardoso, JR, Lambeck, J, de Bie, R & de Vet, HCW 2007, 'Balneotherapy for osteoarthritis', Cochrane Database of Systematic Reviews, no. 4.
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Verhagen, AP, Karels, C, Bierma-Zeinstra, SMA, Feleus, A, Dahaghin, S, Burdorf, A & Koes, BW 2007, 'Exercise proves effective in a systematic review of work-related complaints of the arm, neck, or shoulder', Journal of Clinical Epidemiology, vol. 60, no. 2, pp. 110.e1-110.e14.
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Verhagen, AP, Karels, C, Bierma-Zeinstra, SMA, Feleus, A, Dahaghin, S, Burdorf, A, De Vet, HCW & Koes, BW 2007, 'Ergonomic and physiotherapeutic interventions for treating work-related complaints of the arm, neck or shoulder in adults. A Cochrane systematic review.', Eura Medicophys, vol. 43, no. 3, pp. 391-405.
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BACKGROUND: Conservative interventions such as physiotherapy and ergonomic adjustments (such as keyboard adjustments or ergonomic advice) play a major role in the treatment of most work-related complaints of the arm, neck or shoulder (CANS). Objectives. This systematic review aims to determine whether conservative interventions have a significant impact on outcomes for work-related CANS in adults. Search strategy. We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (March 2005) and Cochrane Rehabilitation and Related Therapies Field Specialised Register (March 2005), the Cochrane Controlled Trials Register (The Cochrane Library, Issue 1, 2005), PubMed, EMBASE, CINAHL, AMED and reference lists of articles. The date of the last search was March 2005. No language restrictions were applied. Selection criteria. We included randomised controlled trials and concurrent controlled trials studying conservative interventions (e.g. exercises, relaxation, physical applications, biofeedback, myofeedback and work-place adjustments) for adults suffering CANS. Data collection and analysis. Two authors independently selected trials from the search yield, assessed the methodological quality using the Delphi list, and extracted relevant data. We pooled data or, in the event of clinical heterogeneity or lack of data, we used a rating system to assess levels of evidence. MAIN RESULTS: For this update we included six additional studies; twenty-one trials in total. Seventeen trials included people with chronic nonspecific neck or shoulder complaints, or nonspecific upper extremity disorders. Over twenty-five interventions were evaluated; six main subgroups of interventions could be determined: exercises, manual therapy, massage, ergonomics, energised splint and individual treatment versus group therapy. Overall, the quality of the studies was poor. In 14 studies a form of exercise was evaluated, and contrary to the previous review we now found lim...
Verhagen, AP, Scholten-Peeters, GGGM, van Wijngaarden, S, de Bie, R & Bierma-Zeinstra, SMA 2007, 'Conservative treatments for whiplash', Cochrane Database of Systematic Reviews, vol. 2011, no. 2.
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Verhagen, AP, Scholten-Peeters, GGM, de Bie, RA & Bierma-Zeinstra, SMA 2007, 'Conservative treatments for whiplash', Cochrane database of systematic reviews (Online), no. 2.
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BACKGROUND: Many treatments are available for whiplash patients but there is little scientific evidence for their accepted use. Patients with whiplash-associated disorders (WAD) can be classified by the severity of signs and symptoms from Grade 0 (no complaints or physical signs) to Grade 4 (fracture or dislocation). OBJECTIVES: To assess the effectiveness of conservative treatment for patients with whiplash injuries rated as Grades 1 or 2 (neck and musculoskeletal complaints). SEARCH STRATEGY: We searched the Cochrane Central Register of Controlled Trials (The Cochrane Library, 2006, Issue 3), MEDLINE, CINAHL, PsycINFO, and PEDro to November 2006 and screened references of identified randomised trials and relevant systematic reviews. SELECTION CRITERIA: We selected randomised controlled trials published in English, French, German or Dutch, that included patients with a whiplash-injury, conservative interventions, outcomes of pain, global perceived effect or participation in daily activities. DATA COLLECTION AND ANALYSIS: Two authors independently assessed the methodological quality using the Delphi criteria and extracted the data onto standardised data-extraction forms. We did not pool the results because of the heterogeneity of the population, intervention and outcomes and lack of data. A pre-planned stratified analysis was performed for three different comparisons. MAIN RESULTS: Twenty-three studies (2344 participants) were included in this update, including nine new studies. A broad variety of conservative interventions were evaluated. Two studies included patients with chronic symptoms (longer than three months), two included subacute (four to six weeks) symptoms, two had undefined duration of symptoms, and 17 studied patients with acute (less than three weeks) symptoms. Only eight studies (33.3%) satisfied one of our criteria of high quality, indicating overall, a poor methodological quality. Interventions were divided into passive (such as rest, immobilisa...
Vidal, RL, Ramírez, OA, Sandoval, L, Koenig-Robert, R, Härtel, S & Couve, A 2007, 'Marlin-1 and conventional kinesin link GABAB receptors to the cytoskeleton and regulate receptor transport', Molecular and Cellular Neuroscience, vol. 35, no. 3, pp. 501-512.
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Vos, C, Verhagen, A, Passchier, J & Koes, B 2007, 'Management of acute neck pain in general practice: a prospective study.', Br J Gen Pract, vol. 57, no. 534, pp. 23-28.
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BACKGROUND: Research on neck pain in primary care is sparse. The role of GPs in taking care of patients with neck pain has not been described so far. This study focused on interested in the interaction between patients and GPs in their first contact on a new episode of neck pain. AIM: To describe GPs' management of acute neck pain in patients and to detail the diagnostic and therapeutic procedures undertaken by GPs and self-care by patients. DESIGN OF STUDY: A prospective cohort study with 1-year follow up. SETTING: General practice in The Netherlands. METHOD: Patients consulting their GP for non-specific acute neck pain lasting no longer than 6 weeks were invited to participate. Questionnaires were collected from patients at baseline and after 6, 12, 26, and 52 weeks. Patients rated their recovery on a 7-point ordinal scale. RESULTS: In total 187 patients were included. At baseline GPs prescribed medication for 42% of patients, mostly non-steroidal anti-inflammatory drugs (56%) or muscle relaxation medication (20%); 51% were referred to a physiotherapist. Seventy-four per cent of referred patients reported recovery at the end of the follow-up year, whereas 79% of non-referred patients reported recovery. Frequently-given advice by the GP was to 'wait and see' (23%), 'improve posture' and 'stay active' (22%) or to 'take a rest' (18%). Self-care by patients included different sources of heat application (79%) and exercises (57%). Complementary medicine was used in 12% of cases and 39% of patients visited their GP again during follow up. Consultation of a medical specialist and ordering of X-rays rarely occurred. CONCLUSION: Management by GPs included a strategy to 'wait and see' for an expected favourable natural course supported by medication, or referral to a physiotherapist.
Willemse-van Son, AHP, Ribbers, GM, Verhagen, AP & Stam, HJ 2007, 'Prognostic factors of long-term functioning and productivity after traumatic brain injury: a systematic review of prospective cohort studies', Clinical Rehabilitation, vol. 21, no. 11, pp. 1024-1037.
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Objective: To systematically review prospective cohort studies that investigated prognostic factors associated with long-term activity limitations or participation restrictions and productivity after a traumatic brain injury. Data sources: PubMed and Psychinfo were searched from 1995 to April 2005, and references were checked. Review methods: Publications were selected if the study assessed prognostic factors for activity limitations or participation restrictions at least one year post injury; outcome was measured with another or additional measure besides the Glasgow Outcome Scale; the design was a prospective cohort study of adult traumatic brain injury patients; the article was a full-text article written in English, French, German or Dutch. Two reviewers independently assessed methodological quality. A study was considered as `high quality' if it satisfied at least half of the maximum available quality score. Results: Thirty-five articles reporting on 14 cohorts were included. Due to heterogeneity in prognostic factors and outcome measures, a best-evidence synthesis was performed. All cohorts were of high quality. Strong evidence for predicting disability was found for older age, pre-injury unemployment, pre-injury substance abuse, and more disability at rehabilitation discharge. Strong prognostic factors for being non-productive were pre-injury unemployment, longer post-traumatic amnesia, more disability at rehabilitation admission, and pre-injury substance abuse. Conclusion: Older age, pre-injury unemployment, pre-injury substance abuse and more disability at rehabilitation discharge are important predictors of long-term disability. Pre-injury unemployment, longer post-traumatic amnesia, more disability at rehabilitation admission and pre-injury substance abuse are important predictors of being non-productive.
