Publications

Dive, L 2023, 'Autonomy and Responsibility' in Di Nucci, E, Lee, J-Y & Wagner, IA (eds), The Rowman and Littlefield Handbook of Bioethics, Rowman & Littlefield Handbook Series, UK, pp. 62-73.
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The Rowman & Littlefield Handbook of Bioethics offers concise, up-to-date, and easy-to-read chapters on a broad range of bioethical topics in the following categories: foundational concepts, theory and method, healthcare ethics, research ...

Dutta, M, Murray, LL, Stark, BC & Bryant, L 2023, 'FOQUSAphasia: An Initiative to Facilitate Research of Spoken Discourse in Aphasia and Its Translation into Improved Evidence-based Practice for Discourse Treatment' in Spoken Discourse Impairments in the Neurogenic Populations, Springer International Publishing, pp. 305-316.
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Liu-Brennan, D 2023, 'Hanabi' in Introducing Japanese Popular Culture, Routledge, pp. 337-346.
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Loomes, MW & Rosenbaum, S 2023, 'Exercise and Psychotherapy in the Treatment of Anxiety Disorders' in Combining Exercise and Psychotherapy to Treat Mental Health, IGI Global, pp. 1-21.
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Anxiety is one of the most common mental health conditions experienced worldwide. As such, there is significant investment into the treatment of this disorder and to alleviate the effects it has on the individual. While various interventions exist, such as pharmacotherapy, psychotherapy, and lifestyle interventions, more is needed to combat the growing scope of anxiety. This chapter presents empirical evidence for combining two effective treatments: psychotherapy and physical exercise. It also suggests some practical ways in which this can be integrated in healthcare systems. Additional recommendations are provided to facilitate this integration of this combined treatment for both consumers and healthcare professionals.

Ridley, EJ, Chapple, LS, Burrell, A, Fetterplace, K, Freeman‐Sanderson, A, Marshall, AP & Neto, AS 2023, 'COVID‐19: Nutrition Perspectives' in Coronavirus Disease 2019 (COVID‐19): A Clinical Guide, Wiley, USA, pp. 428-453.
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This chapter provides a comprehensive look at the unique aspects of providing nutrition therapy for hospitalized patients with COVID‐19, including those who are critically ill, from admission to recovery, covering nutrition‐impacting symptoms, medical management, nutrition screening and assessment, and nutrition practices of delivery and monitoring of nutrition support. It also provides perspective on the implications of a worldwide pandemic on caseload, resourcing, stock shortages, and the logistics of managing the nutrition care of highly infectious patients.

Van Eerdenbrugh, S & O'Brian, S 2023, 'The Camperdown Program' in Sønsterud, H & Węsierska, K (eds), Dialogue without barriers: A comprehensive approach to dealing with stuttering, Agere Aude Foundation for Knowledge and Social Dialogue., Chorzów, Poland, pp. 163-194.

Allen, CG, Olstad, DL, Kahkoska, AR, Guan, Y, Ramos, PS, Steinberg, J, Staras, SAS, Lumpkins, CY, Milko, LV, Turbitt, E, Rahm, AK, Saylor, KW, Best, S, Hatch, A, Santangelo, I & Roberts, MC 2023, 'Extending an Antiracism Lens to the Implementation of Precision Public Health Interventions', American Journal of Public Health, vol. 113, no. 11, pp. 1210-1218.
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Precision public health holds promise to improve disease prevention and health promotion strategies, allowing the right intervention to be delivered to the right population at the right time. Growing concerns underscore the potential for precision-based approaches to exacerbate health disparities by relying on biased data inputs and recapitulating existing access inequities. To achieve its full potential, precision public health must focus on addressing social and structural drivers of health and prominently incorporate equity-related concerns, particularly with respect to race and ethnicity. In this article, we discuss how an antiracism lens could be applied to reduce health disparities and health inequities through equity-informed research, implementation, and evaluation of precision public health interventions. (Am J Public Health. 2023;113(11):1210–1218. https://doi.org/10.2105/AJPH.2023.307386 )

Allinson, CH & Berle, D 2023, 'Association between unmet post-arrival expectations and psychological symptoms in recently arrived refugees', Transcultural Psychiatry, vol. 60, no. 1, pp. 39-51.
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Thwarted expectations regarding one's post-settlement life may challenge the mental health of refugees. The present study aimed to investigate the relationship between pre-arrival expectations and the course of psychological symptoms across time. A secondary analysis of 1,496 principal visa applicants across five waves of the Building a New Life in Australia (BNLA) study was conducted. The cross-sectional associations between expectations on the one hand, and post-traumatic stress (PTSD-8) symptoms and psychological distress (Kessler-6; K6) on the other, were assessed using multiple regression. Latent class growth analysis (LCGA) was used to identify discrete symptom trajectories of psychological symptoms across five years following settlement, and multinomial regressions were used to determine if violated expectations predicted membership of identified PTSD-8 and K6 class trajectories. LCGA supported a four-class solution for the PTSD-8 “Resilient Post Traumatic Stress (PTS)” (54.1%), “Improving PTS” (15.0%), “Deteriorating PTS” (17.3%), and “Persistently High PTS” (13.6%). For the K6, three classes were identified: “Persistently Mild K6” (60.4%), “Resilient K6” (9.4%), and “Persistently High K6” (30.2%). Thwarted expectations were found to significantly predict membership of less favourable symptom trajectories classes in the context of other established predictors. Post-settlement expectations may thus have weak but unique predictive value for the course of psychological symptoms alongside other factors such as older age and financial stress. Implications of these findings for service provision and policy are discussed.

Amador-Fernández, N, Gastelurrutia, MÁ & García-Cárdenas, V 2023, 'Development of self-care in Spanish community pharmacies', Exploratory Research in Clinical and Social Pharmacy, vol. 12, pp. 100337-100337.
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Spain is a European country with over 47.5 million inhabitants and a public National Health System model (i.e., SNS or “Sistema Nacional de Salud”) that provides universal coverage to residents and non-residents. The system is funded primarily by general taxes, and it is managed by the 17 regions that have responsibility for the provision and management of healthcare services in their respective territories. The health system recognizes self-care as an important element where individuals have an important role to play in maintaining their own health and preventing illness. In addition, there are non-governmental organizations that promote self-care and provide resources and support to individuals and health professionals. Over 55 thousand pharmacists work in 22,198 community pharmacies distributed throughout the Spanish territory. Pharmacies are the only setting that provide non-prescription medications, which is one of the most used tools for self-care. In addition, they provide a range of Primary Care services to improve patient outcomes and the efficiency of the SNS. This paper includes a description and a classification of the community pharmacy services following the seven pillars of self-care established by the International Self-Care Foundation: - Related to pillars 1 to 4 and 6, Spanish community pharmacists provide health promotion, health education, health information and nutritional assessment. - In relation to pillar 5, the services offered are HIV and syphilis screening, colorectal and cervix cancer screening, SARS-CoV-2 screening test and communication, diabetes, high blood pressure and hypercholesterolemia screening. Regarding the programs for avoiding/stopping drug use: methadone supply, syringe exchange and smoking cessation. Another important service is immunization. Spanish community pharmacists are not legally allowed to vaccinate; however, they contribute through education, or vaccines supply, among others. - For the pillar 7, commu...

Amador-Fernández, N, Jenkinson, SP & Berger, J 2023, 'Vision and practice of self-care for community pharmacy in Switzerland', Exploratory Research in Clinical and Social Pharmacy, vol. 9, pp. 100253-100253.
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Switzerland is a federal country with a liberal health system built on private mandatory health insurance where the government has three different roles (health protector, guarantor of the offered care and regulator). Health is mostly considered as a responsibility that lies with the individual person. Swiss health policies do not include the term 'self-care', although, the federal policy strategy established for this decade (Health2030) includes objectives and lines of action, some of which could be classified as self-care. Swiss policies do not specify the role of health professionals; therefore, it is up to each canton (the terminology used to describe a state of the Swiss Confederation), organization or enterprise to stipulate it. Regarding pharmacists, 1844 community pharmacies (CPs) take care of nearly 260,000 patients each day. The CPs play an important role in self-care that includes activities such as improving patients' health literacy, screening for different health problems, self-medication education or recommendation related to non-prescription medication. The government understands and emphasizes the importance of CPs' role in primary health care to overcome some of the health care system challenges, part of these actions related to self-care. However, there is scope for expansion regarding the role of the CPs in self-care. Nowadays the services and activities related are driven by health authorities (i.e., pharmacists' autonomous prescribing, vaccination, strategy for the prevention of non-communicable diseases or digitization of electronic patients' record), professional pharmacy associations (i.e., netCare® or screening tests), health foundations (i.e., prevention of addiction) and/or private stakeholders such as chain pharmacies (i.e., screening tests). The possibility of including some of these services related to self-care (even when no medication is supplied) as covered services for the mandatory health insurance is currently politi...

Amato Maguire, M, Onslow, M, Lowe, R, O’Brian, S & Menzies, R 2023, 'Searching for Lidcombe Program mechanisms of action: Inter-turn speaker latency', Clinical Linguistics & Phonetics, vol. 37, no. 12, pp. 1091-1103.
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The Lidcombe Program is a well-established and efficacious treatment for early stuttering, but little is currently known about its mechanisms of action. The present report explores the possibility that inter-turn speaker latency might be associated with such mechanisms of action. Inter-turn speaker latency was measured in audio recordings of children, parents, and clinicians conversing, taken during Lidcombe Program treatment consultations. Five clinicians reduced their inter-turn speaker latencies during clinical consultations when they were speaking to children, in comparison with when they were speaking to parents. It is possible that inter-turn speaker latency is associated with the Lidcombe Program treatment process vicariously, and this possibility requires further research.

Amberg, A, Crispin, M, Koeppenkastrop, L, Munday, I & McCambridge, AB 2023, 'Unravelling dystonic pain; a mixed methods survey to explore the language of dystonic pain and impact on life', Disability and Rehabilitation, vol. 45, no. 12, pp. 1975-1983.
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PURPOSE: Dystonia is a neurological disorder characterised by involuntary muscle contractions. Pain is the primary non-motor symptom, and limited studies have investigated how dystonic pain is experienced. This study aimed to investigate how people with isolated dystonia describe their pain and compare across subgroups of dystonia. METHODS: Anonymous online survey via social media asking participants to describe their pain in their own words, complete the McGill Pain Questionnaire (MPQ), and answer demographic questions. Thematic analysis identified common themes and frequencies were calculated for demographic and MPQ data. RESULTS: One-hundred and sixty-five respondents were included (mean age 51 years, 85% female). Thematic analysis identified four major themes 'Physical sensations', 'Temporal features', 'Destruction', 'Impact on life' with several sub-themes. The most chosen MPQ descriptor was 'exhausting' followed by 'tight,' 'sharp,' 'pulling,' and 'aching'. The most common descriptors showed similar prevalence across subgroups of dystonia. CONCLUSION: As no objective tests for pain exist, pain sufferers must use language to describe their pain experience. People with isolated dystonia used sensory words combined with metaphorical language to detail temporal features of pain, as well as destructive internal battles or feelings of external forces acting upon them, and the significant toll pain has on everyday life. Implications for rehabilitationPain is a common and debilitating non-motor symptom for people living with dystonia and should be discussed in a persons treatment plan.Pain sufferers use language to discuss their pain experience with others and report they don't feel well understood by others including health professionals.People with dystonic pain commonly described physical sensations, temporal features, destructive forces, and the impact on life caused by their pain.Findings suggest the experience of pain with dystonia is varied and better pain m...

Arnáez, S, García-Soriano, G, Castro, J, Berle, D & Starcevic, V 2023, 'The Spanish version of the short form of the Cyberchondria Severity Scale (CSS-12): Testing the factor structure and measurement invariance across genders', Current Psychology, vol. 42, no. 24, pp. 20686-20695.
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AbstractCyberchondria refers to excessive and repeated online health-related searching, which is associated with increased distress and anxiety. The Cyberchondria Severity Scale (CSS) is the most widely used measure for assessment of cyberchondria, and its shortened version (CSS-12) has recently been developed. The aim of the present study was to develop the Spanish version of the CSS-12 and test its psychometric properties. A community sample of 432 Spanish-speaking adults (67.6% women; mean age = 36.00 ± 15.22 years) completed the Spanish translation of CSS-12 along with measures of health anxiety, obsessive-compulsive, anxiety and depressive symptoms. The Spanish version of the CSS-12 comprises a general cyberchondria factor and four specific factors (‘excessiveness’, ‘compulsion’, ‘distress’, and ‘reassurance’). Multi-group confirmatory factor analysis indicated measurement invariance across gender groups. Internal consistency values for the total score and subscales were good to excellent. The CSS-12 showed strong correlations with health anxiety, and moderate to low correlations with anxiety, obsessive-compulsive and depressive symptoms, supporting the convergent and divergent validity of the CSS-12, respectively. In conclusion, these results show that the CSS-12 is a valid and reliable tool for measuring cyberchondria in both genders in the general Spanish population.

Avramovic, P, Rietdijk, R, Attard, M, Kenny, B, Power, E & Togher, L 2023, 'Cognitive and Behavioral Digital Health Interventions for People with Traumatic Brain Injury and Their Caregivers: A Systematic Review', Journal of Neurotrauma, vol. 40, no. 3-4, pp. 159-194.
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Traumatic brain injury (TBI) leads to cognitive linguistic deficits that significantly impact on quality of life and well-being. Digital health offers timely access to specialized services; however, there are few synthesized reviews in this field. This review evaluates and synthesizes reports of digital health interventions in TBI rehabilitation and caregiver education. Systematic searches of nine databases (PsycINFO, MEDLINE, CINAHL, Embase, Cochrane Library, Scopus, Web of Science Core Collection, speechBITE, and PsycBITE) were conducted from database inception to February 2022. Studies were included of interventions where the primary treatment focus (> 50%) was on improving communication, social, psychological or cognitive skills of people with TBI and/or communication partners. Data on participants, characteristics of the interventions, outcome measures and findings were collected. Risk of bias was accounted for through methodological quality assessments (PEDro-P and PEDro+, Risk of Bias in N-of-1 Trials) and intervention description. Qualitative data was analyzed using thematic synthesis. Forty-four articles met eligibility criteria: 20 randomized controlled trials, three single-case experimental designs, six non-randomized controlled trials, nine case series studies, and two case studies. Studies comprised 3666 people with TBI and 213 carers. Methodological quality was varied and intervention description was poor. Most interventions were delivered via a single digital modality (e.g., telephone), with few using a combination of modalities. Five interventions used co-design with key stakeholders. Digital health interventions for people with TBI and their caregivers are feasible and all studies reported positive outcomes; however, few included blind assessors. Improved methodological rigor, clearly described intervention characteristics and consistent outcome measurement is recommended. Further research is needed regarding multi-modal digital health ...

Bailey, PE, Leon, T, Ebner, NC, Moustafa, AA & Weidemann, G 2023, 'A meta-analysis of the weight of advice in decision-making', Current Psychology, vol. 42, no. 28, pp. 24516-24541.
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AbstractThe degree to which people take advice, and the factors that influence advice-taking, are of broad interest to laypersons, professionals, and policy-makers. This meta-analysis on 346 effect sizes from 129 independent datasets (N = 17, 296) assessed the weight of advice in the judge-advisor system paradigm, as well as the influence of sample and task characteristics. Information about the advisor(s) that is suggestive of advice quality was the only unique predictor of the overall pooled weight of advice. Individuals adjusted estimates by 32%, 37%, and 48% in response to advisors described in ways that suggest low, neutral, or high quality advice, respectively. This indicates that the benefits of compromise and averaging may be lost if accurate advice is perceived to be low quality, or too much weight is given to inaccurate advice that is perceived to be high quality. When examining the three levels of perceived quality separately, advice-taking was greater for subjective and uncertain estimates, relative to objective estimates, when information about the advisor was neutral in terms of advice quality. Sample characteristics had no effect on advice-taking, thus providing no evidence that age, gender, or individualism influence the weight of advice. The findings contribute to current theoretical debates and provide direction for future research.

Baker, C, Bryant, L & Power, E 2023, 'The effects of virtual reality immersion on the content and structure of the narrative discourse of healthy adults', International Journal of Language & Communication Disorders, vol. 58, no. 6, pp. 2049-2061.
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AbstractBackgroundNarrative discourse is central to effective participation in conversations. When discourse is assessed in people with communication disability, structured tasks (e.g., picture descriptions) provide experimental control, while unstructured tasks (e.g., personal narratives) represent more natural communication. Immersive virtual reality (VR) technology may provide a solution by creating standardized experiences for narrative retell, therefore balancing ecological validity and experimental control in discourse assessment. Research is needed to understand how VR immersion affects narrative retell, first for adults with no communication disability, before application with adults with aphasia or related communication disability.AimsTo assess (1) the effects of VR immersion on the linguistic content and structure of narrative retells in a healthy adult population; and (2) whether VR immersion can influence the way a narrative is retold so that the speaker conveys their own experience, rather than the experience of the characters they are watching.Methods & ProceduresIn this pilot cohort study, 13 healthy adult participants with no reported communication disability watched an animated short film and a comparable immersive VR short film in a randomized order. Participants were asked to retell the events of the story after each condition in as much detail as possible.Outcomes & ResultsMean length of utterance (in morphemes) was significantly higher in the video condition compared with the VR condition. Significantly more first‐person pronouns were used in the VR condition compared with the video condition. No other measures of linguistic content or structure were significantly differen...

Bani Saeid, A, Patel, VK, Mehndiratta, S, Rajput, R, Kundu, RK, Singh, SK, Chellappan, DK, Kokkinis, S, De Rubis, G, Collet, T, Paudel, KR, Hansbro, PM & Dua, K 2023, 'Dissecting the in vitro fate of plant-derived bioactive encapsulated nanoparticles in lung diseases', Food Bioscience, vol. 56, pp. 103205-103205.
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Barakat, S, Burton, AL, Cunich, M, Hay, P, Hazelton, JL, Kim, M, Lymer, S, Madden, S, Maloney, D, Miskovic-Wheatley, J, Rogers, D, Russell, J, Sidari, M, Touyz, S & Maguire, S 2023, 'A randomised controlled trial of clinician supported vs self-help delivery of online cognitive behaviour therapy for Bulimia Nervosa', Psychiatry Research, vol. 329, pp. 115534-115534.
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High dropout rates and poor adherence associated with digital interventions have prompted research into modifications of these treatments to improve engagement and completion rates. This trial aimed to investigate the added benefit of clinician support when paired alongside a ten-session, online cognitive behaviour therapy (CBT) self-help intervention for bulimia nervosa (BN). As part of a three-arm, phase II randomised controlled trial, 114 participants (16 years or over) with full or subthreshold BN were randomly assigned to complete the intervention in a self-help mode (with administrative researcher contact; n = 38), with adjunct clinician support (weekly 30-minute videoconferencing sessions; n = 37), or a no-treatment waitlist control (WLC; n = 39). Baseline to post-treatment (12-weeks) decreases in objective binge episode frequency were significantly greater for clinician-supported participants as compared to WLC, but not for self-help when compared to WLC. However, due to continued improvements for self-help across follow-up (24-weeks), both arms outperformed WLC when analysed as an overall rate of change across three timepoints. Clinician-supported participants outperformed self-help in regards to laxative use and dietary restraint. Our results demonstrate that good clinical outcomes can be achieved with a relatively brief online CBT-based program even in the absence of structured clinical support, indicating a possible overreliance upon clinician support as a primary adherence-facilitating mechanism.

Barbosa, JC, Comachio, J, Marques, AP, Saragiotto, BT & Magalhaes, MO 2023, 'Effect of a telerehabilitation exercise program versus a digital booklet with self-care for patients with chronic non-specific neck pain: a protocol of a randomized controlled trial assessor-blinded, 3 months follow-up', Trials, vol. 24, no. 1, p. 616.
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Abstract Background Neck pain is the fourth worldwide leading cause of disability and represents 22% of musculoskeletal disorders. Conservative intervention has been strongly recommended to treat chronic neck pain and Telerehabilitation is the alternative for the treatment of musculoskeletal conditions. There is a lack of high-quality research on the effects of telerehabilitation in patients with neck pain and functional disability. Therefore, this study aims to evaluate the effect of a telerehabilitation exercise program versus a digital booklet only with self-care information in individuals with non-specific chronic neck pain. Methods This is a prospectively registered, assessor-blinded, two-arm randomized controlled trial comparing a telerehabilitation exercise program versus a digital booklet with self-care information. Seventy patients will be recruited with non-specific chronic neck pain. Follow-ups will be conducted post-treatment, 6 weeks, and 3 months after randomization. The primary outcome will be disability at post-treatment (6 weeks) measured using neck pain disability. Secondary outcomes will be pain intensity levels, global perceived effect, self-efficacy, quality of life, kinesiophobia, and adherence to treatment. In our hypothesis, patients allocated to the intervention group experience outcomes that are similar to those of those assigned to the self-care digital booklet. Our hypothesis can then be approved or disapproved based on the results of the study. Discussion This randomized clinical trial will provide reliable information on the use of telerehabilitation to treat patients with chronic non-specific neck pain.

Baroni, MP, Hespanhol, L, Miyamoto, GC, Daniel, CR, Fernandes, LG, dos Reis, FJJ, Pate, JW & Saragiotto, BT 2023, 'Implementation of an online pain science education for chronic musculoskeletal pain in Brazilian public health system: protocol for a hybrid type III randomised controlled trial with economic evaluation', BMC Musculoskeletal Disorders, vol. 24, no. 1, p. 277.
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Abstract Background Although clinical practice guidelines recommend pain education as the first-line option for the management of chronic musculoskeletal pain, there is a lack of pain education programmes in healthcare. Thus, digital health programmes can be an effective tool for implementing pain education strategies for public health. This trial will aim to analyse the implementation and effectiveness outcomes of three online pain science education strategies in the Brazilian public health system (SUS) for individuals with chronic musculoskeletal pain. Methods We will conduct a hybrid type III effectiveness-implementation randomised controlled trial with economic evaluation. We will include adult individuals with chronic musculoskeletal pain, recruited from primary healthcare in the city of Guarapuava, Brazil. Individuals will be randomised to three implementation groups receiving a pain science education intervention (EducaDor) but delivered in different modalities: group 1) synchronous online; group 2) asynchronous videos; and group 3) interactive e-book only. Implementation outcomes will include acceptability, appropriateness, feasibility, adoption, fidelity, penetration, sustainability, and costs. We will also assess effectiveness outcomes, such as pain, function, quality of life, sleep, self-efficacy, and adverse effects. Cost-effectiveness and cost-utility analyses will be conducted from the SUS and societal perspectives. The evaluations will be done at baseline, post-intervention (10 weeks), and 6 months. Discussion This study will develop and implement a collaborative intervention model involving primar...

Baroni, MP, Jacob, MFA, Rios, WR, Fandim, JV, Fernandes, LG, Chaves, PI, Fioratti, I & Saragiotto, BT 2023, 'The state of the art in telerehabilitation for musculoskeletal conditions', Archives of Physiotherapy, vol. 13, no. 1, p. 1.
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Abstract Background Given the rapid advances in communication technology and the need that emerged from the COVID-19 pandemic, telehealth initiatives have been widely used worldwide. This masterclass aims to provide an overview of telerehabilitation for musculoskeletal conditions, synthesizing the different terminologies used to describe telehealth and telerehabilitation, its effectiveness and how to use it in clinical practice, barriers and facilitators for the implementation in health services, and discuss the need of a curriculum education for the near future. Main body Telerehabilitation refers to the use of information and communication technologies provided by any healthcare professionals for rehabilitation services. Telerehabilitation is a safe and effective option in the management of musculoskeletal conditions in different models of delivery. There are many technologies, with different costs and benefits, synchronous and asynchronous, that can be used for telerehabilitation: telephone, email, mobile health, messaging, web-based systems and videoconferences applications. To ensure a better practice of telerehabilitation, the clinician should certify safety and access, and appropriateness of environment, communication, technology, assessment, and therapeutic prescription. Despite the positive effect of telerehabilitation in musculoskeletal disorders, a suboptimal telerehabilitation implementation may have happened due to the COVID-19 pandemic, especially in countries where telehealth was not a reality, and clinicians lacked training and guidance. This emphasizes the need to identify the necessary curriculum content to guide future clinicians in their skills and knowledge for telerehabilitation. There are some challenges and barriers that mu...

Barrett, JA, Calvert, FL, Gonsalvez, CJ & Shires, AG 2023, 'A qualitative investigation into perceptions of scientist-practitioner competence within supervision during psychology training programmes', Australian Psychologist, vol. 58, no. 2, pp. 80-93.
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Objective: Clinical supervision plays an important role in competency development during psychology practitioner training. How the scientist-practitioner competency is operationalised, disseminated, and evaluated in supervision is unclear. This study aimed to explore supervisor and trainee attitudes, opinions, and perceptions of scientist-practitioner competence. It also sought to understand what supervisors are doing in supervision to develop and assess the scientist-practitioner competency, as well as how trainees demonstrate the competency in supervision. Method: Three focus groups comprised 12 trainees and a total of 12 supervisor individual telephone interviews were conducted, where participants reflected on their supervision experiences, responding to questions about the scientist-practitioner competency. Results: A thematic analysis resulted in the identification of core themes and subthemes. Core themes identified were 1) Scientist-Practitioner Model as a Foundation to Professional and Ethical Practice; 2) The Translation of Science into Real-World Practice; 3) Flexibility to Learn/Change within the Scientist-Practitioner Model; 4) Supervision as the Route to Developing Scientist Practitioner Skills and Knowledge; and 5) Barriers and Challenges to Bridging Science and Practice. Conclusions: Findings reveal specific ways supervisors and trainees can acquire and demonstrate scientist-practitioner competence in supervision during professional training. This may assist with self- and other evaluation of scientist-practitioner competence in supervision. Implications for training, education, and supervision are discussed.

Berle, D, Starcevic, V, Wootton, B, Arnáez, S & Baggio, S 2023, 'A network approach to understanding obsessions and compulsions', Journal of Obsessive-Compulsive and Related Disorders, vol. 36, pp. 100786-100786.
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Berlowitz, DJ, Mathers, S, Hutchinson, K, Hogden, A, Carey, KA, Graco, M, Whelan, B-M, Charania, S, Steyn, F, Allcroft, P, Crook, A & Sheers, NL 2023, 'The complexity of multidisciplinary respiratory care in amyotrophic lateral sclerosis', Breathe, vol. 19, no. 3, pp. 220269-220269.
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Motor neurone disease/amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder with no known cure, where death is usually secondary to progressive respiratory failure. Assisting people with ALS through their disease journey is complex and supported by clinics that provide comprehensive multidisciplinary care (MDC).This review aims to apply both a respiratory and a complexity lens to the key roles and areas of practice within the MDC model in ALS. Models of noninvasive ventilation care, and considerations in the provision of palliative therapy, respiratory support, and speech and language therapy are discussed. The impact on people living with ALS of both inequitable funding models and the complexity of clinical care decisions are illustrated using case vignettes. Considerations of the impact of emerging antisense and gene modifying therapies on MDC challenges are also highlighted.The review seeks to illustrate how MDC members contribute to collective decision-making in ALS, how the sum of the parts is greater than any individual care component or health professional, and that the MDCper seadds value to the person living with ALS. Through this approach we hope to support clinicians to navigate the space between what are minimum, guideline-driven, standards of care and what excellent, person-centred ALS care that fully embraces complexity could be.Educational aimsTo highlight the complexities surrounding respiratory care in ALS.To alert clinicians to the risk that complexity of ALS care may modify the effectiveness of any specific, evidence-based therapy for ALS.To describe the importance of person-centred care and shared decision-making in optimising care in ALS.

Bier, J, Verhagen, A, Ostelo, R, Chiarotto, A & Koes, B 2023, 'The Effect of a New Payment System on Physiotherapeutic Management of Patients With Low Back Pain in Primary Care', Archives of Physical Medicine and Rehabilitation, vol. 104, no. 5, pp. 738-744.
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Black, JA, Paparo, J & Wootton, BM 2023, 'A Preliminary Examination of Treatment Barriers, Preferences, and Histories of Women with Symptoms of Social Anxiety Disorder', Behaviour Change, vol. 40, no. 4, pp. 267-277.
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AbstractSocial anxiety disorder (SAD) is a common mental health condition that is characterised by a persistent fear of social or performance situations. Despite effective treatments being available, many individuals with SAD do not seek treatment or delay treatment seeking for many years. The aim of the present study was to examine treatment barriers, treatment histories, and cognitive behavioural therapy (CBT) delivery preferences in a sample of women with clinically relevant SAD symptoms. Ninety-nine women (Mage = 34.90, SD = 11.28) completed the online questionnaires and were included in the study. Participants were recruited from advertisements on community noticeboards and posts on social media. The results demonstrated that less than 5% of those who received psychological treatment in the past were likely to have received best-practice CBT. The most commonly cited barriers to accessing treatment for women with SAD related to direct costs (63%) and indirect costs (e.g., transport/childcare) (28%). The most preferred treatment delivery method overall was individual face-to-face treatment (70%). The study demonstrates a need to provide a variety of treatment options in order to enhance access to empirically supported treatment for women with SAD.

Boufous, S, Möller, H, Patton, G, Woodward, M, Stevenson, MR, Senserrick, T, Mclean, R, Cullen, P, Wang, A, Rogers, K, Chen, H-Y & Ivers, RQ 2023, 'Acculturation and risk of traffic crashes in young Asian-born Australian drivers', Injury Prevention, vol. 29, no. 1, pp. 74-78.
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The study examines changes over time in crash risk differences between young Australian drivers born in Asia and those born in Australia.Data from the 2003 baseline survey of the DRIVE cohort of 20 806 young drivers aged 17–24 years were linked to police, hospital and death data up until 2016. The association between country of birth and crash was investigated using flexible parametric survival models adjusted for confounders.Six months after baseline, the crash risk in Asian-born drivers was less than half that of their Australian-born counterparts (mean HR, MHR 0.41; 95% CI 0.29 to 0.57), only to increase steadily over time to resemble that of Australian-born drivers 13 years later (MHR 0.94; 95% CI 0.66 to 1.36).This is likely to be associated with acculturation and the adoption by young Asian-born Australian drivers of driving behaviour patterns akin to those born locally. This needs to be considered in future road safety campaigns.

Brassel, S, Brunner, M, Power, E, Campbell, A & Togher, L 2023, 'Speech-Language Pathologists' Views of Using Virtual Reality for Managing Cognitive-Communication Disorders Following Traumatic Brain Injury', American Journal of Speech-Language Pathology, vol. 32, no. 2S, pp. 907-923.
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Purpose: Using virtual reality (VR) to support rehabilitation is an emerging area of research that may offer people with communication disorders a stable and safe communication environment to practice their communication skills. There are currently no VR applications that have been designed to assess or treat cognitive-communication disorders (CCDs) following traumatic brain injury (TBI). Therefore, this study aimed to explore the views of speech-language pathologists (SLPs) who work with people who have a TBI to generate ideas and considerations for using VR in rehabilitation for CCDs. VR researchers were included to provide expert advice about VR technology. Method: A total of 14 SLPs and three VR specialists participated in an online interview or focus group. Semistructured discussions explored participants' perspectives related to potential ideas for VR use and any perceived barriers and facilitators to VR implementation for managing CCDs following TBI. Data were video- and audio-recorded, transcribed, and analyzed qualitatively using thematic analysis. Results: Three main themes were generated from thematic analysis: VR is a tool that could enhance clinical practice, the need to consider and navigate potential red flags, and solutions to pave the way forward. Suggestions to overcome perceived barriers to VR use were also provided. Discussion: Participants expressed interest in using VR for rehabilitation of CCDs following TBI. However, potential barriers and risks to use should be considered prior to implementation. The findings offer guidance to support future...

Brown, O & Newton-John, TRO 2023, 'The influence of the significant other on treatment adherence in chronic pain management: a qualitative analysis', Psychology & Health, vol. 38, no. 11, pp. 1572-1586.
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Brunner, M, Rietdijk, R, Avramovic, P, Power, E, Miao, M, Rushworth, N, MacLean, L, Brookes, A-M & Togher, L 2023, 'Developing Social-ABI-lity: An Online Course to Support Safe Use of Social Media for Connection After Acquired Brain Injury', American Journal of Speech-Language Pathology, vol. 32, no. 2S, pp. 924-940.
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Purpose: People who have an acquired brain injury (ABI) experience challenges using social media. Inversely, rehabilitation clinicians report feeling inadequately prepared to support them in its use. We aimed to develop a collaboratively designed, evidence-based online training resource to support people with an ABI to learn about using social media. Key recommendations for course design have previously been identified through a mixed methods approach, including (a) qualitative exploration of the experiences of people who use social media after ABI, (b) a scoping review to identify key features and effective teaching approaches from existing social media skills training programs. Method: Further design recommendations were obtained in this mixed methods study through (c) collaborative design of course content and features with 23 people, including people with living experience of ABI and other key stakeholders, and (d) a pilot trial of the course prototype with four participants who had an ABI (two men, two women; aged 28–69 years). Results: Training needs to be interactive, including practical components addressing online safety and wellbeing, and to explain how to use social media platforms to connect with others. The first social-ABI-lity prototype incorporated these findings. Pilot data indicated that the prototype was beneficial, with participants demonstrating small increases in social media confidence and knowledge. Areas for further refinement were also identified. Conclusion: The social-ABI-lity self-directed online course is the first of its kind to suppor...

Burton, B, Isaacs, M, Brogan, E, Shrubsole, K, Kilkenny, MF, Power, E, Godecke, E, Cadilhac, DA, Copland, D & Wallace, SJ 2023, 'An updated systematic review of stroke clinical practice guidelines to inform aphasia management', International Journal of Stroke, vol. 18, no. 9, pp. 1029-1039.
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Background: Aphasia is a common consequence of stroke, and people who live with this condition experience poor outcomes. Adherence to clinical practice guidelines can promote high-quality service delivery and optimize patient outcomes. However, there are currently no high-quality guidelines specific to post-stroke aphasia management. Aims: To identify and evaluate recommendations from high-quality stroke guidelines that can inform aphasia management. Summary of review: We conducted an updated systematic review in accordance with PRISMA guidelines to identify high-quality clinical guidelines published between January 2015 and October 2022. Primary searches were performed using electronic databases: PubMed, EMBASE, CINAHL, and Web of Science. Gray literature searches were conducted using Google Scholar, guideline databases, and stroke websites. Clinical practice guidelines were evaluated using the Appraisal of Guidelines and Research and Evaluation (AGREE II) tool. Recommendations were extracted from high-quality guidelines (scored > 66.7% on Domain 3: “Rigor of Development”), classified as aphasia-specific or aphasia-related, and categorized into clinical practice areas. Evidence ratings and source citations were assessed, and similar recommendations were grouped. Twenty-three stroke clinical practice guidelines were identified and 9 (39%) met our criteria for rigor of development. From these guidelines, 82 recommendations for aphasia management were extracted: 31 were aphasia-specific, 51 aphasia-related, 67 evidence-based, and 15 consensus-based. Conclusion: More than half of stroke clinical practice guidelines identified did not meet our criteria for rigorous development. We identified 9 high-quality guidelines and 82 re...

Casey, LJ, Bowman, SJ, Power, E, McAloon, J & Wootton, BM 2023, 'Coping with the Australian marriage law postal survey and its legacy: “I create meaning and joy and connection and community”', Journal of Gay & Lesbian Social Services, vol. 35, no. 4, pp. 456-487.
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Casey, LJ, Bowman, SJ, Power, E, McAloon, J & Wootton, BM 2023, 'The Cognitive-Behavioral Impact of the Australian Marriage Law Postal Survey: A Reflexive Thematic Analysis.', Psychology of Sexual Orientation and Gender Diversity, vol. 10, no. 1, pp. 91-102.
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Marriage equality legislation was introduced in Australia in 2017 following a national survey of enrolled voters conducted via the postal system (“the postal survey”). Consistent with other major anti-LGBTQ rights campaigns, research has demonstrated that this event posed a unique source of social stress for LGBTQ people. This study seeks to expand the clinical utility of previous research by employing a cognitive-behavioral lens to explore the life stressors reported by LGBTQ Australians during the postal survey. During the postal survey period, a sample of 2,200 LGBTQ Australians answered the open-ended question, “Do you think the public discussion about marriage equality and the marriage equality postal survey has affected you and/or your family? If so, how?” Seven hundred of these responses were randomly selected and analyzed using reflexive thematic analysis. Cognitive themes were hyperawareness of stigma, social and political exclusion, changes in self-perception, and fear of harm. Affective themes were anger, anxiety, and sadness. Behavioral themes were avoidance, changing social relationships, hiding identity, and preoccupation. The physiological theme was exhaustion. The results have implications for the assessment and treatment of LGBTQ people experiencing distress in the face of future anti-LGBTQ rights campaigns.

Casey, LJ, Bowman, SJ, Wootton, BM, McAloon, J & Power, E 2023, '“A Tremendous Outpouring of Love and Affection”: A Template Analysis of Positive Experiences During a Major LGBTQ Rights Campaign', Journal of Homosexuality, vol. 70, no. 9, pp. 1936-1958.
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Human rights for lesbian, gay, bisexual, transgender, and queer or questioning (LGBTQ) people have frequently been decided via popular vote. Australia conducted one such vote on the topic of marriage equality in 2017. Research has tended to focus on the negative experiences reported by LGBTQ people during such votes, with little attention paid to any positive experiences identified. This paper seeks to redress that imbalance, reporting the findings of two qualitative studies asking LGBTQ Australians about positive experiences during the marriage equality vote. The first study analyzed 673 typed responses collected during the two-month voting period, while the second analyzed interview data from 19 LGBTQ Australians collected two-and-a-half years after the vote. Both were analyzed using template analysis. Results identified sources of support, types of support, empowerment through activism, changes in general and LGBTQ communities, and positive personal changes. As public votes continue to be used to determine LGBTQ human rights, the findings may guide interventions to help LGBTQ people and their allies cope with such campaigns.

Chakraborty, A, Paudel, KR, Wang, C, De Rubis, G, Chellappan, DK, Hansbro, PM, Samuel, CS & Dua, K 2023, 'Anti-inflammatory and anti-fibrotic effects of berberine-loaded liquid crystalline nanoparticles.', EXCLI J, vol. 22, pp. 1104-1108.
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Chambers, C, Lichten, L, Crook, A, Uhlmann, WR & Dratch, L 2023, 'Incorporating Genetic Testing Into the Care of Patients With Amyotrophic Lateral Sclerosis/Frontotemporal Degeneration Spectrum Disorders', Neurology Clinical Practice, vol. 13, no. 5, pp. e200201-e200201.
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Purpose of ReviewAmyotrophic lateral sclerosis (ALS) and frontotemporal degeneration (FTD) spectrum disorders have a strong genetic component. Genetic counselors are a limited resource, and therefore, other providers must be prepared to integrate genetic testing into their practice.Recent FindingsRecent ALS/FTD studies have demonstrated that lack of family history does not preclude a genetic etiology. The benefits of a genetic diagnosis have expanded to include the potential to treat; thus, genetic testing is increasingly recommended to be offered to all persons with ALS/FTD.SummaryOffering genetic testing to persons with ALS/FTD spectrum disorders should be part of routine clinical neurologic care. All genetic testing should include discussion about the medical and psychosocial implications of testing for the patient and family members. Neurologists should be prepared to facilitate this process and recognize when referral to a genetic counselor is indicated.

Chang, K-YJ, Angell, B, Rogers, K, Jan, S & Keay, L 2023, 'Cost–benefit analysis of orientation and mobility programs for adults with vision disability: a contingent valuation study', Disability and Rehabilitation, vol. 45, no. 5, pp. 857-865.
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Chang, W, Jenkins, LC, Humburg, P & Schabrun, SM 2023, 'Human assumed central sensitization in people with acute non‐specific low back pain: A cross‐sectional study of the association with brain‐derived neurotrophic factor, clinical, psychological and demographic factors', European Journal of Pain, vol. 27, no. 4, pp. 530-545.
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AbstractBackgroundEarly evidence suggests human assumed central sensitization (HACS) is present in some people with acute low back pain (LBP). Factors influencing individual variation in HACS during acute LBP have not been fully explored. We aimed to examine the evidence for HACS in acute LBP and the contribution of brain‐derived neurotrophic factor (BDNF), clinical, psychological and demographic factors to HACS.MethodsParticipants with acute LBP (<6 weeks after pain onset, N = 118) and pain‐free controls (N = 57) from a longitudinal trial were included. Quantitative sensory testing including pressure and heat pain thresholds and conditioned pain modulation, BDNF serum concentration and genotype and questionnaires were assessed.ResultsThere were no signs of HACS during acute LBP at group level when compared with controls. Sensory measures did not differ when compared between controls and LBP participants with different BDNF genotypes. Two LBP subgroups with distinct sensory profiles were identified. Although one subgroup (N = 60) demonstrated features of HACS including pressure/heat pain hypersensitivity at a remote site and deficient conditioned pain modulation, pain severity and disability did not differ between the two subgroups. Variation in sensory measures (~33%) was partially explained by BDNF genotype, sex, age and psychological factors.ConclusionsThis study confirms that HACS is present in some people with acute LBP, but this was not associated with pain or disability. Further, no relationship was observed between BDNF and HACS in acute LBP. More research is needed to understand factors contributing to individ...

Chang, W-J, Buscemi, V, Liston, M, Nicholas, M, Graven-Nielsen, T, Hodges, P, Wasinger, V, Stone, L, Dorsey, S, McAuley, J, Schabrun, S & Jenkins, L 2023, 'The Understanding persistent Pain Where it ResiDes study of low back pain cohort profile.', New Zealand Journal of Physiotherapy, vol. 51, no. 3, pp. 199-216.
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Despite chronic low back pain (LBP) being considered a biopsychosocial condition for diagnosis and management, few studies haveinvestigated neurobiological risk factors thought to underpin the transition from acute to chronic LBP. The aim of this research is todescribe the methodology, compare baseline characteristics between acute LBP participants and pain-free controls, and compareLBP participants with or without completed follow-up. One hundred and twenty individuals experiencing acute LBP and 57 painfree controls were recruited to participate in the Understanding persistent Pain Where it ResiDes (UPWaRD) study. Neurobiological,psychological, and sociodemographic data were collected at baseline, and at 3 and 6 months. Ninety-five participants (79%)provided outcome data at 3-month follow-up and 96 participants (80%) at 6 months. Compared to controls, LBP participants inthe UPWaRD cohort were older, had a higher BMI, a higher prevalence of comorbidities, and higher medication usage. Higherdepression, anxiety and stress, lower pain self-efficacy, and higher pain catastrophising during acute LBP were correlated with higher6-month pain and disability. This cohort provides novel and significant opportunities to increase understanding of neurobiological riskfactors of LBP. Future findings endeavour to provide new targets for treatment and prevention of chronic LBP. Additional prioritiesinclude exploring epigenetic and proteomic biomarkers of poor LBP outcome

Charytan, DM, Mahaffey, KW, Jardine, MJ, Cannon, CP, Neal, B, Lambers Heerspink, HJ, Agarwal, R, Bakris, GL, de Zeeuw, D, Levin, A, Pollock, C, Zhang, H, Zinman, B, Rosenthal, N, Perkovic, V, Di Tanna, GL, Yu, J, Rogers, K, Arnott, C & Wheeler, DC 2023, 'Cardiorenal protective effects of canagliflozin in CREDENCE according to glucose lowering', BMJ Open Diabetes Research & Care, vol. 11, no. 3, pp. e003270-e003270.
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IntroductionRelationships between glycemic-lowering effects of sodium glucose co-transporter 2 inhibitors and impact on kidney and cardiovascular outcomes are uncertain.Research design and methodsWe analyzed 4395 individuals with prebaseline and postbaseline hemoglobin A1c (HbA1c) randomized to canagliflozin (n=2193) or placebo (n=2202) in The Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation trial. Effects on HbA1c were assessed using mixed models. Mediation of treatment effects by achieved glycemic control was analyzed using proportional hazards regression with and without adjustment for achieved HbA1c. End points included combined kidney or cardiovascular death, end-stage kidney disease or doubling of serum creatinine (primary trial outcome), and individual end point components.ResultsHbA1c lowering was modified by baseline estimated glomerular filtration rate (eGFR). For baseline eGFR 60–90, 45–59, and 30–44 mL/min/1.73 m2, overall HbA1c (canagliflozin vs placebo) decreased by −0.24%, −0.14%, and −0.08% respectively and likelihood of >0.5% decrease in HbA1c decreased with ORs of 1.47 (95% CI 1.27 to 1.67), 1.12 (0.94 to 1.33) and 0.99 (0.83 to 1.18), respectively. Adjustment for postbaseline HbA1c marginally attenuated canagliflozin effects on primary and kidney composite outcomes: unadjusted HR 0.67 (95% CI 0.57 to 0.80) and 0.66 (95% CI 0.53 to 0.81); adjusted for week 13 HbA1c, HR 0.71 (95% CI 0.060 to 0.84) and 0.68 (95% CI 0.55 to 0.83). Results adjusted for time-varying HbA1c or HbA1c as a cubic spline were similar and consistent with preserved clinical benefits across a range of excellent and poor glycemic control.ConclusionsThe glycemic effects of c...

Chaudhry, MT, McCambridge, AB, Russell, S, Yong, K, Inglis, SC, Verhagen, A & Ferguson, C 2023, 'User profile of people contacting a stroke helpline (StrokeLine) in Australia: a retrospective cohort study', Contemporary Nurse, vol. 59, no. 6, pp. 434-442.
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Cheever, J, Cayoun, BA, Elphinstone, B & Shires, AG 2023, 'Confirmation and Validation of the Equanimity Scale-16 (ES-16)', Mindfulness, vol. 14, no. 1, pp. 148-158.
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Objectives: Equanimity is an accepting and non-reactive mental state that has gained increased recognition as a key mechanism of mindfulness-based interventions (MBIs). The recently developed Equanimity Scale-16 (ES-16) provides a measure of equanimity that can be used to assess such interventions; however, to date, evidence of its factor structure and temporal stability is lacking. The present study aimed to provide the first confirmatory factor analysis of the ES-16, and to further examine the validity and test-retest reliability of the measure. Method: The Qualtrics online platform was used to administer the ES-16 and other questionnaires in order to assess validity and collected demographic information in 395 adults from the general community (76.2% females and 23.8% males). Questionnaires were then re-administered four weeks later to assess test-retest reliability. Results: Confirmatory factor analysis indicated that one- or two-factor (i.e., Experiential Acceptance, Non-reactivity) models provided adequate model fit with the addition of covariances between semantically similar items. However, adequate model fit was also obtained with a bi-factor model, suggesting that there is an underlying unidimensionality as all items tap into the latent equanimity construct. The ES-16 showed good internal consistency (ω = 0.90); test-retest reliability (n = 161; r = 0.81, p < 0.001) over four weeks; and convergent validity, illustrated by significant correlations in the expected directions with the Two-Factor Equanimity Scale, Depression Anxiety Stress Scales, and Difficulties in Emotion Regulation Scale-Short Form. Conclusions: The present results support previous research showing that the ES-16 is a valid and reliable self-report measure to assess overall trait equanimity. Given the central role of equanimity in MBIs, the ES-16 may also assist in further understanding mechanisms of change in MBIs.

Chen, L, Debono, D & Hemsley, B 2023, 'A bite closer: Using 3D food printing to achieve Sustainable Development Goals 2, 3, 9 and 17', International Journal of Speech-Language Pathology, vol. 25, no. 1, pp. 58-61.
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Purpose: This commentary paper focuses on four Sustainable Development Goals (SDGs): zero hunger (SDG 2), good health and well-being (SDG 3), industry, innovation and infrastructure (SDG 9), and partnerships for the goals (SDG 17). Each bite of food has the potential to impact on nutrition and well-being, particularly for the older adult aged over 65 years with swallowing disability. Better attention to the shape of the foods presented for consumption may help improve access to food and nutrition through food shaping methods such as 3D food printing. Target objectives across these four SDGs should help to improve the physical and emotional health of older people with swallowing disability who need texture-modified foods.Result: We discuss the potential for methods to improve food shaping and influence better health outcomes for older people, particularly those with swallowing disability. Texture-modified food should be both nourishing and enjoyable while being safe to swallow without coughing or choking; to improve nutrition, health, and quality of life.Conclusion: Along with temperature and taste, the shape of texture-modified foods influences the appeal of the food as important elements of food design. The link between the enjoyment of food and nutrition sets the foundation for a good quality of life for older people. 3D food printing, among other food shaping methods, helps establish this link through the creation of nutritious and appealing foods. Applying the targets for SDGs relating to food shaping techniques will involve innovation and collaboration with older people and multiple disciplines.

Chen, L, Hemsley, B & Debono, D 2023, 'The Impact of Food-Shaping Techniques on Nutrition, Mealtime Experiences, and Quality of Life for Older Adults in Aged Care Settings: A Systematic Review', CURRENT NUTRITION REPORTS, vol. 12, no. 4, pp. 744-766.
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Chen, L, Hemsley, B & Debono, D 2023, 'The Impact of Food-Shaping Techniques on Nutrition, Mealtime Experiences, and Quality of Life for Older Adults in Aged Care Settings: A Systematic Review', Current Nutrition Reports, vol. 12, no. 4, pp. 744-766.
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Abstract Objective Food-shaping methods, particularly for texture-modified foods, present numerous opportunities to improve the visual appeal of food and potentially the nutrition of older people with dysphagia (swallowing difficulty). This review appraises and synthesizes the evidence on the use of food-shaping methods to enhance nutrition in older adults with swallowing difficulties. Methods In August 2022, five electronic databases (PubMed, CINAHL, Scopus, Cochrane Library, and Web of Science) were searched for original research related to the intersection of nutrition, food shaping, and older adults with swallowing difficulties. Characteristics of included studies were described and data from results and findings extracted for analysis across studies. Results Eighteen studies met the inclusion criteria and encompassed a variety of settings, including aged care settings (n = 15) and food science laboratories (n = 3). Qualitative and quantitative findings demonstrated a variety of impacts of food shaping for the older adult with swallowing difficulty, including enhanced nutrition and wellbeing. The content themes identified across studies were: links between food shaping and nutrition, shaping food for individual choice, food shaping for enjoyment, a combination of supporting factors, collaborative inter-disciplinary teams and roles, and implementation aligns with local contexts. Conclusion With recent growth in research on food shaping, the body of studies reviewed identified...

Cheng, BBY, Ryan, BJ, Copland, DA & Wallace, SJ 2023, 'Prognostication in post-stroke aphasia: Perspectives of people with aphasia on receiving information about recovery', Neuropsychological Rehabilitation, vol. 33, no. 5, pp. 871-902.
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Chisholm, AK, Lami, F, Haebich, KM, Ure, A, Brignell, A, Maloof, T, Pride, NA, Walsh, KS, Maier, A, Rouel, M, Granader, Y, Barton, B, Darke, H, Fuelscher, I, Dabscheck, G, Anderson, VA, Williams, K, North, KN & Payne, JM 2023, 'Sex- and age-related differences in autistic behaviours in children with neurofibromatosis type 1', Journal of Autism and Developmental Disorders, vol. 53, no. 7, pp. 2835-2850.
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Christensen, I, Power, E, Togher, L & Norup, A 2023, '“Communication Is Not Exactly My Field, but It Is Still My Area of Work”: Staff and Managers' Experiences of Communication With People With Traumatic Brain Injury', American Journal of Speech-Language Pathology, vol. 32, no. 2S, pp. 827-847.
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Purpose:Communication between people with traumatic brain injury (TBI) and rehabilitation staff can be impacted by cognitive-communication disorders. Communication partner training (CPT) programs hold potential to improve communication between people with TBI and their communication partners. To tailor CPT programs to the rehabilitation environment, it is critical to understand the nature of communicative interactions for staff members. This study explores staff and managers' experiences of communication with people with TBI in the rehabilitation setting.Method:Individual semistructured videoconference interviews were carried out with staff members (n= 22) and managers (n= 4) varying in terms of professions and length of work experience. Interviews were guided by a phenomenological approach to gain comprehensive knowledge of staff and managers' lived experiences of communication with people with TBI.Results:Four themes with nine subthemes were generated: (a) cognitive-communication disorders challenge interaction (communication is socially inappropriate, the diversity of presenting symptoms associated with TBI is demanding), (b) staff struggle in communication (there is a breakdown of communicative collaboration, communication increases staff's workload, emotional well-being of staff is at risk), (c) communication context is crucial (tasks affect communication, extending the professional roles), and (d) staff want communication knowledge and skills (needs vary according to work experience, access to tailored strategies, and feedback).Conclusions:Staff and managers experienced communication with people with TBI as highly demanding. The socially inappropriate communication i...

Clague, CA, Prnjak, K & Mitchison, D 2023, '“I don't want them to judge me”: Separating out the role of fear of negative evaluation, neuroticism, and low self-esteem in eating disorders', Eating Behaviors, vol. 49, pp. 101708-101708.
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Clarke, A, Rose, TA & Meredith, PJ 2023, 'Language skills and interpersonal trust in adolescents with and without mental illness', International Journal of Speech-Language Pathology, vol. 25, no. 4, pp. 589-607.
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Clayton, NA, Walker, E & Freeman–Sanderson, A 2023, 'Clinical profile and recovery pattern of dysphagia in the COVID-19 patient: A prospective observational cohort within NSW', Australian Critical Care, vol. 36, no. 2, pp. 262-268.
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Cullen, P, Mőller, H, Baffsky, R, Martiniuk, A, Senserrick, T, Rogers, K, Woodward, M, Stevenson, MR, McLean, R, Sawyer, S, Patton, G & Ivers, RQ 2023, 'Self-harm in adolescence and risk of crash: a 13-year cohort study of novice drivers in New South Wales, Australia', Injury Prevention, vol. 29, no. 4, pp. 302-308.
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IntroductionSelf-harm and suicide are leading causes of morbidity and death for young people, worldwide. Previous research has identified self-harm is a risk factor for vehicle crashes, however, there is a lack of long-term crash data post licensing that investigates this relationship. We aimed to determine whether adolescent self-harm persists as crash risk factor in adulthood.MethodsWe followed 20 806 newly licensed adolescent and young adult drivers in the DRIVE prospective cohort for 13 years to examine whether self-harm was a risk factor for vehicle crashes. The association between self-harm and crash was analysed using cumulative incidence curves investigating time to first crash and quantified using negative binominal regression models adjusted for driver demographics and conventional crash risk factors.ResultsAdolescents who reported self-harm at baseline were at increased risk of crashes 13 years later than those reporting no self-harm (relative risk (RR) 1.29: 95% CI 1.14 to 1.47). This risk remained after controlling for driver experience, demographic characteristics and known risk factors for crashes, including alcohol use and risk taking behaviour (RR 1.23: 95% CI 1.08 to 1.39). Sensation seeking had an additive effect on the association between self-harm and single-vehicle crashes (relative excess risk due to interaction 0.87: 95% CI 0.07 to 1.67), but not for other types of crashes.DiscussionOur findings add to the growing body of evidence that self-harm during adolescence predicts a range of poorer health outcomes, including motor vehicle crash risks that warrant further investigation and consideration in road safety interventions. Complex interventions addressing self-harm in adolescence, as well as road safe...

Cunningham, CN, Jenkins, LC, Chang, W-J, McAuley, JH & Schabrun, SM 2023, 'Relative and absolute reliability of somatosensory evoked potentials in response to non-noxious electrical stimulation of the paraspinal muscles in healthy participants at an interval of 3-months', International Journal of Neuroscience, vol. 133, no. 1, pp. 103-109.
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Daly, R, Hetherington, K, Hazell, E, Wadling, BR, Tyrrell, V, Tucker, KM, Marshall, GM, Ziegler, DS, Lau, LMS, Trahair, TN, O’Brien, TA, Collins, K, Gifford, AJ, Haber, M, Pinese, M, Malkin, D, Cowley, MJ, Karpelowsky, J, Drew, D, Jacobs, C & Wakefield, CE 2023, 'Precision Medicine Is Changing the Roles of Healthcare Professionals, Scientists, and Research Staff: Learnings from a Childhood Cancer Precision Medicine Trial', Journal of Personalized Medicine, vol. 13, no. 7, pp. 1033-1033.
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Precision medicine programs aim to utilize novel technologies to identify personalized treatments for children with cancer. Delivering these programs requires interdisciplinary efforts, yet the many groups involved are understudied. This study explored the experiences of a broad range of professionals delivering Australia’s first precision medicine trial for children with poor-prognosis cancer: the PRecISion Medicine for Children with Cancer (PRISM) national clinical trial of the Zero Childhood Cancer Program. We conducted semi-structured interviews with 85 PRISM professionals from eight professional groups, including oncologists, surgeons, clinical research associates, scientists, genetic professionals, pathologists, animal care technicians, and nurses. We analyzed interviews thematically. Professionals shared that precision medicine can add complexity to their role and result in less certain outcomes for families. Although many participants described experiencing a greater emotional impact from their work, most expressed very positive views about the impact of precision medicine on their profession and its future potential. Most reported navigating precision medicine without formal training. Each group described unique challenges involved in adapting to precision medicine in their profession. Addressing training gaps and meeting the specific needs of many professional groups involved in precision medicine will be essential to ensure the successful implementation of standard care.

Dann, KM, Veldre, A, Miles, S, Sumner, P, Hay, P & Touyz, S 2023, 'Measuring cognitive flexibility in anorexia nervosa: Wisconsin Card Sorting Test versus cued task-switching', Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity, vol. 28, no. 1, p. 60.
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Abstract Purpose The Wisconsin Card Sorting Test (WCST) is the most common measure of cognitive flexibility in anorexia nervosa (AN), but task-switching paradigms are beginning to be utilized. The current study directly compared performance on a cued task-switching measure and the WCST to evaluate their association in participants with a lifetime diagnosis of AN, and to assess which measure is more strongly associated with clinical symptoms. Methods Forty-five women with a lifetime diagnosis of AN completed the WCST, cued color-shape task-switching paradigm, Anti-saccade Keyboard Task, Running Memory Span, Eating Disorder Examination Questionnaire, Depression Anxiety Stress Scales short form and Eating Disorder Flexibility Index. Results There was no evidence of a significant association between WCST perseverative errors and cued task-switching switch costs. Results suggest lower working memory capacity is a determinant of higher perseverative error rate. When controlling for mood variables, neither cognitive flexibility measure was a significant independent predictor of symptom severity. Conclusions Results provide support for previous suggestions that WCST perseverative errors could occur due to difficulties with working memory, sensitivity to feedback, and issues with concept formation. Cued task-switching paradigms may provide a useful measure of cognitive flexibility for future eating disorders research by reducing task-specific confounds. Level of eviden...

Datsyuk, JK, Paudel, KR, Rajput, R, Kokkinis, S, El Sherkawi, T, Singh, SK, Gupta, G, Chellappan, DK, Yeung, S, Hansbro, PM, Oliver, BGG, Santos, HA, Dua, K & De Rubis, G 2023, 'Emerging applications and prospects of NFκB decoy oligodeoxynucleotides in managing respiratory diseases', Chemico-Biological Interactions, vol. 385, pp. 110737-110737.
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De Rubis, G, Paudel, KR, Corrie, L, Mehndiratta, S, Patel, VK, Kumbhar, PS, Manjappa, AS, Disouza, J, Patravale, V, Gupta, G, Manandhar, B, Rajput, R, Robinson, AK, Reyes, R-J, Chakraborty, A, Chellappan, DK, Singh, SK, Oliver, BGG, Hansbro, PM & Dua, K 2023, 'Applications and advancements of nanoparticle-based drug delivery in alleviating lung cancer and chronic obstructive pulmonary disease', Naunyn-Schmiedeberg's Archives of Pharmacology.
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Lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are among the leading causes of mortality worldwide. Cigarette smoking is among the main aetiologic factors for both ailments. These diseases share common pathogenetic mechanisms including inflammation, oxidative stress, and tissue remodelling. Current therapeutic approaches are limited by low efficacy and adverse effects. Consequentially, LC has a 5-year survival of < 20%, while COPD is incurable, underlining the necessity for innovative treatment strategies. Two promising emerging classes of therapy against these diseases include plant-derived molecules (phytoceuticals) and nucleic acid-based therapies. The clinical application of both is limited by issues including poor solubility, poor permeability, and, in the case of nucleic acids, susceptibility to enzymatic degradation, large size, and electrostatic charge density. Nanoparticle-based advanced drug delivery systems are currently being explored as flexible systems allowing to overcome these limitations. In this review, an updated summary of the most recent studies using nanoparticle-based advanced drug delivery systems to improve the delivery of nucleic acids and phytoceuticals for the treatment of LC and COPD is provided. This review highlights the enormous relevance of these delivery systems as tools that are set to facilitate the clinical application of novel categories of therapeutics with poor pharmacokinetic properties. This picture was generated with BioRender.

De Rubis, G, Paudel, KR, Liu, G, Agarwal, V, MacLoughlin, R, de Jesus Andreoli Pinto, T, Singh, SK, Adams, J, Nammi, S, Chellappan, DK, Oliver, BGG, Hansbro, PM & Dua, K 2023, 'Berberine-loaded engineered nanoparticles attenuate TGF-β-induced remodelling in human bronchial epithelial cells', Toxicology in Vitro, vol. 92, pp. 105660-105660.
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Dell’Aquila, A & Berle, D 2023, 'Predictors of alcohol and substance use among people with post-traumatic stress disorder (PTSD): findings from the NESARC-III study', Social Psychiatry and Psychiatric Epidemiology, vol. 58, no. 10, pp. 1509-1522.
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Abstract Purpose The self-medication hypothesis suggests people may develop Alcohol Use Disorder (AUD) or Non-Alcohol Substance Use Disorder (NA-SUD) following PTSD as a maladaptive way of coping with PTSD symptoms. Given that an accumulation of trauma experiences and interpersonal trauma increase the likelihood and severity of PTSD, we sought to determine whether the number and type of traumas additionally predict AUD and NA-SUD following PTSD. Methods We analysed data from 36,309 adult participants in the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) study (M = 45.63 years, SD = 17.53, 56.3% female) who were administered semi-structured diagnostic interviews of trauma exposure and PTSD, AUD and NA-SUD symptoms. Results Individuals with PTSD were more likely to have an AUD or NA-SUD than those without PTSD. Endorsement of a greater number of traumas was associated with greater odds of having PTSD, AUD, or NA-SUD. Experience of interpersonal trauma was related to greater odds of having PTSD and subsequent AUD or NA-SUD than not experiencing interpersonal trauma. Multiple experiences of interpersonal trauma compared to one interpersonal trauma exposure also increased the odds of having PTSD followed by AUD or NA-SUD. Conclusions Interpersonal trauma and multiple experiences of interpersonal trauma may result in individuals turning to alcohol and substances as a way to alleviate intolerable PTSD symptomology, aligning with the self-medication hypothesis. Our findings highl...

Dive, L, Archibald, AD, Freeman, L & Newson, AJ 2023, 'How should severity be understood in the context of reproductive genetic carrier screening?', Bioethics, vol. 37, no. 4, pp. 359-366.
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AbstractReproductive genetic carrier screening provides information about people's chance of having children with certain genetic conditions. Severity of genetic conditions is an important criterion for their inclusion in carrier screening programmes. However, the concept of severity is conceptually complex and underspecified. We analyse why severity is an important concept in carrier screening and for reproductive decision‐making and show that assessments of severity can also have normative societal implications. While some genetic conditions are unambiguously associated with a high degree of suffering, there are many factors that contribute to how severe a condition is perceived to be, and perspectives will vary. Attempts to classify genetic conditions according to their severity tend to prioritise biomedical information at the expense of incorporating qualitative aspects of the impact of genetic conditions on people's lives. Further complexity arises because some genotypes can present with variable phenotypes and because some conditions are not always experienced in the same way by all people who have them. To acknowledge this complexity, we argue that an understanding of severity needs to distinguish between the severity of a genetic condition—requiring a generalised approach for purposes of policy development and programme design—and the severity of an instance of a genetic condition in a particular person. Families making reproductive decisions also require access to diverse experiences of the qualitative aspects of living with genetic conditions. As a result, reproductive carrier screening programmes must recognise and respond to the complexity inherent in determining the severity of genetic conditions.

Dive, L, Freeman, L & McEwen, A 2023, 'Genetic Counsellors play a key role in supporting ethically responsible expanded universal carrier screening', European Journal of Human Genetics, vol. 31, no. 1, pp. 5-6.
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Dive, L, Holmes, I & Newson, AJ 2023, 'Is It Just for a Screening Program to Give People All the Information They Want?', The American Journal of Bioethics, vol. 23, no. 7, pp. 34-42.
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Dorstyn, DS, Chur-Hansen, A, Mansell, E, Murphy, G, Roberts, RM, Stewart, P, Potter, E, Kneebone, I & Craig, A 2023, 'Facilitators and barriers to employment for persons with chronic spinal cord injury or disorder: A qualitative study framed by the person-environment-occupation model', The Journal of Spinal Cord Medicine, vol. 46, no. 2, pp. 246-255.
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CONTEXT/OBJECTIVE: Prolonged unemployment is common for people living with a spinal cord injury or disorder (SCI/D) and can impact negatively on quality of life. The present study examines stakeholder perspectives and experiences with the job search process in order to identify service gaps and return-to-work solutions. DESIGN: In-depth semi-structured interviews were thematically analysed, with questions focused on factors that can help or hinder efforts to gain employment. Generated themes were then applied to the Person-Environment-Occupation (PEO) systems model of participation. SETTING: Community-based disability service provider in South Australia. PARTICIPANTS: Purposive sample of persons with SCI/D (n = 8) and rehabilitation professionals (n = 4). RESULTS: Person-centred themes were strongly endorsed by both groups and focused on incentives of, and motivation for, employment. Equally important to the job search process were individual expectations and attitudes, particularly job readiness. Environmental facilitators included employers' positive attitude, although workplace discrimination remained a concern. Occupation-based barriers, rather than opportunities, were identified - namely, difficulties in SCI/D self-management, the need for timely functional assessments, and more opportunities for education, upskilling and retraining. CONCLUSIONS: The PEO model provides a broad framework to better understand the complex return-to-work process for people with a SCI/D and, potentially, uncover tangible solutions. The suggestion is that vocational rehabilitation should go beyond skills training and include motivational support to enhance job readiness. This must be done on a case-by-case basis. There is also a need for active and covert discrimination to be addressed through employment policies. The findings will be used to develop intervention targets for a newly established vocational rehabilitation service.

Elbourn, E, MacWhinney, B, Fromm, D, Power, E, Steel, J & Togher, L 2023, 'TBIBank: An International Shared Database to Enhance Research, Teaching and Automated Language Analysis for Traumatic Brain Injury Populations', Archives of Physical Medicine and Rehabilitation, vol. 104, no. 5, pp. 824-829.
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Traumatic brain injury (TBI) has been established as a priority research area for public health, affecting an estimated 69 million individuals worldwide each year. Large-scale collaborative datasets may help to better understand this heterogenous and chronic health condition. In this paper, we present TBIBank; an innovative digital health resource that aims to establish a shared database for the study of communication disorders after TBI. We provide an overview of the current database, the standard discourse protocol used for the main TBIBank corpus, and the automated language analyses that can enable diagnostic profiling, comparative evaluation of treatment effects and profiling of recovery patterns. We also highlight the e-learning component of the digital health resource as a research translation tool. We conclude with a discussion of the potential research, clinical, and educational applications of TBIBank and future directions for expanding this digital resource.

Elgort, I & Veldre, A 2023, 'Word processing before explicit attention: Using the gaze-contingent boundary paradigm in L2 reading research', Research Methods in Applied Linguistics, vol. 2, no. 3, pp. 100074-100074.
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Eye-movement studies investigating second language (L2) word processing during reading are growing exponentially. However, what information L2 readers are able to process parafoveally is a less researched topic. The gaze-contingent boundary paradigm (Rayner, 1975) allows researchers to manipulate visual information in an upcoming word during reading, tapping into real-time word processing without awareness. This article provides an overview of experimental studies of parafoveal word processing in reading, followed by a methodological review of the use of the boundary paradigm in L2 and bilingual research. We synthesize key methodological details (including preview type, eye-movement measures) and findings of 15 experiments that met our search criteria, concluding that the parafoveal preview effect observed when reading in the first language is also present in L2 reading. We propose how the gaze-contingent boundary paradigm can be used to study L2 lexical knowledge and factors that affect its development. Finally, we provide advice and instructions for designing and conducting boundary paradigm experiments.

El-Helou, R, Ryan, B & Kneebone, I 2023, 'Development of the “Kalmer” relaxation intervention: co-design with stroke survivors with aphasia', Disability and Rehabilitation, vol. 45, no. 9, pp. 1517-1529.
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PURPOSE: Anxiety is common after stroke and more prevalent in survivors with aphasia. Relaxation is an effective first-line therapy. The current study aimed to obtain the perspectives of stroke survivors with aphasia to inform the development of an accessible, technology-based, relaxation intervention. MATERIALS AND METHODS: Qualitative co-design methods were used with twelve people with aphasia after stroke. The 'Kalmer' Relaxation treatment package materials were iteratively based on participants' experiences and preferences; barriers and facilitators to treatment compliance were explored. Participants were also asked to consider how the intervention might be evaluated in a research trial. RESULTS: A thematic analysis highlighted the importance and need for the development of an appropriate and inclusive relaxation product, to be implemented by health professionals early post-stroke. Several behavioural strategies to improve treatment adherence were recommended. Participants had varying perspectives on clinically meaningful treatment outcomes. CONCLUSIONS: Overall, a co-designed accessible relaxation product was viewed as a necessary component of usual stroke care. Acceptability and feasibility and preliminary efficacy of the 'Kalmer' intervention should be trialled in future studies. IMPLICATIONS FOR REHABILITATIONCo-designing psychological interventions for people with aphasia after stroke is needed to meet the needs of this at-risk population.Technology-based relaxation interventions to manage anxiety after stroke are viewed positively by people with aphasia and deemed acceptable and feasible.Clinical trials of these co-designed relaxation interventions are required before recommending integration into routine practice.

Fandim, JV, Hinman, RS, Øverås, CK, Sharma, S, Belton, J, Oliveira, VC, Dear, BF, Parker, R, Ghai, B, Bennell, KL, Ferreira, P, Hartvigsen, J & Saragiotto, BT 2023, 'One step at a time. Shaping consensus on research priorities and terminology in telehealth in musculoskeletal pain: an international modified e-Delphi study', BMC Musculoskeletal Disorders, vol. 24, no. 1, p. 783.
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Abstract Background Telehealth has emerged as an alternative model for treatment delivery and has become an important component of health service delivery. However, there is inconsistency in the use of terminologies and a lack of research priorities in telehealth in musculoskeletal pain. The purpose of this international, multidisciplinary expert panel assembled in a modified three-round e-Delphi survey is to achieve a consensus on research priorities and for the standard terminology for musculoskeletal pain telehealth practice. Methods In this international modified e-Delphi survey, we invited an expert panel consisting of researchers, clinicians, consumer representatives, industry partners, healthcare managers, and policymakers to participate in a three-round e-Delphi. Expert panels were identified through the Expertscape website, PubMed database, social media, and a snowball approach. In Round 1, potential research priorities and terminologies were presented to panel members. Panel members rated the agreement of each research priority on a 5-point Likert scale and an 11-point numerical scale, and each terminology on a 5-point Likert scale for the 'telehealth in musculoskeletal pain ' field over rounds. At least 80% of the panel members were required to agree to be deemed a consensus. We analyzed the data descriptively and assessed the stability of the results using the Wilcoxon matched-pairs signed rank test. Results We performed an international e-Delphi survey from February to August 2022. Of 694 invited people, 160 panel members participated in the first round, 133 in the second round (83% retention), and 134 in the third round (84% ...

Fatima, R, Prasher, P, Sharma, M, Chellappan, DK, Gupta, G, Singh, SK, Patravale, VB & Dua, K 2023, 'Aminated Polysaccharides: Unveiling a new frontier for enhanced therapeutic efficacy', Journal of Drug Delivery Science and Technology, vol. 89, pp. 105090-105090.
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Fernandes, LG, Mescouto, KA, Costa, LOP & Saragiotto, BT 2023, 'Ways public health users interact with online health information: a qualitative study', HEALTH AND TECHNOLOGY, vol. 13, no. 6, pp. 905-913.
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Fernandes, LG, Mescouto, KA, Costa, LOP & Saragiotto, BT 2023, 'Ways public health users interact with online health information: a qualitative study', Health and Technology, vol. 13, no. 6, pp. 905-913.
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Abstract Purpose The use of internet for health-related purposes has increased in the past years; however, the overabundance of information led the world to a health “infodemic”. Little is known about the ways public health users seek health information online and how it influences the relationship between patients and healthcare practitioners. We aimed to investigate how public health users seek health information online and how this practice affects health encounters. Methods We conducted a qualitative study in a public secondary level healthcare facility. Thirty participants were interviewed using a semi-structured grid designed upon the definition of digital health literacy. Participants were mostly women with an average age of 50 years old and educational level equal to or lower than high school degree. Traditionally and digitally illiterate participants participated in the study. Data analysis was performed using a reflexive thematic analysis underpinned by critical theory. Results We identified three interrelated themes: (1) failing to be a digitally engaged patient, (2) health information on the internet resonates better with individuals’ literacy, and (3) vulnerability is welcomed on the internet. Themes explored power dynamics that appeared to be mediated by formal knowledge, sociocultural contexts, use of technical language, and the presence of emotional and affective domains. Conclusion Our findings suggest that health information online might facilitate the understanding of technical terms and fill an emotional gap oft...

Fernandez-Llimos F, F 2023, 'Mejorando la calidad de las publicaciones y avanzando en todos los paradigmas de la investigación de la farmacia asistencial, clínica y social: las declaraciones de Granada', Farmacéuticos Comunitarios, vol. 15, no. 4, pp. 31-38.
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Fernandez-Llimos, F & Garcia-Cardenas, V 2023, 'The importance of using standardized terminology in titles and abstracts of pharmacy practice articles', Research in Social and Administrative Pharmacy, vol. 19, no. 2, pp. 190-191.
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Fernandez-Llimos, F, Desselle, S, Stewart, D, Garcia-Cardenas, V, Babar, Z-U-D, Bond, C, Dago, A, Jacobsen, R, Nørgaard, LS, Polidori, C, Sanchez-Polo, M, Santos-Ramos, B, Shcherbakova, N & Tonin, F 2023, 'Improving the quality of publications in and advancing the paradigms of clinical and social pharmacy practice research: The Granada statements', Research in Social and Administrative Pharmacy, vol. 19, no. 5, pp. 830-835.
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Fernandez-Llimos, F, Desselle, S, Stewart, D, Garcia-Cardenas, V, Babar, Z-U-D, Bond, C, Dago, A, Jacobsen, R, Nørgaard, LS, Polidori, C, Sanchez-Polo, M, Santos-Ramos, B, Shcherbakova, N & Tonin, F 2023, 'Improving the quality of publications in and advancing the paradigms of clinical and social pharmacy practice research: The Granada statements', Journal of Pharmaceutical Policy and Practice, vol. 16, no. 1.
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AbstractPharmacy and pharmaceutical sciences embrace a series of different disciplines. Pharmacy practice has been defined as “the scientific discipline that studies the different aspects of the practice of pharmacy and its impact on health care systems, medicine use, and patient care”. Thus, pharmacy practice studies embrace both clinical pharmacy and social pharmacy elements. Like any other scientific discipline, clinical and social pharmacy practice disseminates research findings using scientific journals. Clinical pharmacy and social pharmacy journal editors have a role in promoting the discipline by enhancing the quality of the articles published. As has occurred in other health care areas (i.e., medicine and nursing), a group of clinical and social pharmacy practice journal editors gathered in Granada, Spain to discuss how journals could contribute to strengthening pharmacy practice as a discipline. The result of that meeting was compiled in these Granada Statements, which comprise 18 recommendations gathered into six topics: the appropriate use of terminology, impactful abstracts, the required peer reviews, journal scattering, more effective and wiser use of journal and article performance metrics, and authors’ selection of the most appropriate pharmacy practice journal to submit their work.

Fernandez-Llimos, F, Desselle, S, Stewart, D, Garcia-Cardenas, V, Babar, Z-U-D, Bond, C, Dago, A, Jacobsen, R, Norgaard, LS, Polidori, C, Sanchez-Polo, M, Santos-Ramos, B, Shcherbakova, N & Tonin, FS 2023, 'Improving the Quality of Publications in and Advancing the Paradigms of Clinical and Social Pharmacy Practice Research: The Granada Statements', PHARMACEUTICAL CARE ESPANA, vol. 25, no. 2, pp. 65-82.

Fernandez-Llimos, F, Desselle, S, Stewart, D, Garcia-Cardenas, V, Babar, Z-U-D, Bond, C, Dago, A, Jacobsen, R, Nørgaard, LS, Polidori, C, Sanchez-Polo, M, Santos-Ramos, B, Shcherbakova, N & Tonin, FS 2023, 'Improving the quality of publications in and advancing the entire paradigms of clinical and social pharmacy practice research: the Granada statements', Journal de Pharmacie Clinique, vol. 42, no. 2, pp. 53-60.
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Fernandez-Llimos, F, Desselle, S, Stewart, D, Garcia-Cardenas, V, Babar, Z-U-D, Bond, C, Dago, A, Jacobsen, R, Nørgaard, LS, Polidori, C, Sanchez-Polo, M, Santos-Ramos, B, Shcherbakova, N & Tonin, FS 2023, 'Improving the quality of publications in and advancing the paradigms of clinical and social pharmacy practice research: the Granada statements', International Journal of Pharmacy Practice.
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Pharmacy and pharmaceutical sciences embrace a series of different disciplines. Pharmacy practice has been defined as 'the scientific discipline that studies the different aspects of the practice of pharmacy and its impact on health care systems, medicine use, and patient care'. Thus, pharmacy practice studies embrace both clinical pharmacy and social pharmacy elements. Like any other scientific discipline, clinical and social pharmacy practice disseminates research findings using scientific journals. Clinical pharmacy and social pharmacy journal editors have a role in promoting the discipline by enhancing the quality of the articles published. As has occurred in other healthcare areas (i.e. medicine and nursing), a group of clinical and social pharmacy practice journal editors gathered in Granada, Spain to discuss how journals could contribute to strengthening pharmacy practice as a discipline. The result of that meeting was compiled in these Granada Statements, which comprise 18 recommendations gathered into 6 topics, namely the appropriate use of terminology, impactful abstracts, the required peer reviews, journal scattering, more effective and wiser use of journal and article performance metrics and authors' selection of the most appropriate pharmacy practice journal to submit their work.

Fernandez-Llimos, F, Desselle, S, Stewart, D, Garcia-Cardenas, V, Babar, Z-U-D, Bond, C, Dago, A, Jacobsen, R, Nørgaard, LS, Polidori, C, Sanchez-Polo, M, Santos-Ramos, B, Shcherbakova, N & Tonin, FS 2023, 'Improving the quality of publications in and advancing the paradigms of clinical and social pharmacy practice research: the Granada Statements', International Journal of Clinical Pharmacy, vol. 45, no. 2, pp. 285-292.
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AbstractPharmacy and pharmaceutical sciences embrace a series of different disciplines. Pharmacy practice has been defined as “the scientific discipline that studies the different aspects of the practice of pharmacy and its impact on health care systems, medicine use, and patient care”. Thus, pharmacy practice studies embrace both clinical pharmacy and social pharmacy elements. Like any other scientific discipline, clinical and social pharmacy practice disseminates research findings using scientific journals. Clinical pharmacy and social pharmacy journal editors have a role in promoting the discipline by enhancing the quality of the articles published. As has occurred in other health care areas (i.e., medicine and nursing), a group of clinical and social pharmacy practice journal editors gathered in Granada, Spain to discuss how journals could contribute to strengthening pharmacy practice as a discipline. The result of that meeting was compiled in these Granada Statements, which comprise 18 recommendations gathered into six topics: the appropriate use of terminology, impactful abstracts, the required peer reviews, journal scattering, more effective and wiser use of journal and article performance metrics, and authors’ selection of the most appropriate pharmacy practice journal to submit their work.

Fernandez-Llimos, F, Desselle, S, Stewart, D, Garcia-Cardenas, V, Babar, Z-U-D, Bond, C, Dago, A, Jacobsen, R, Nørgaard, LS, Polidori, C, Sanchez-Polo, M, Santos-Ramos, B, Shcherbakova, N & Tonin, FS 2023, 'Improving the quality of publications in and advancing the paradigms of clinical and social pharmacy practice research: The Granada Statements', Exploratory Research in Clinical and Social Pharmacy, vol. 9, pp. 100229-100229.
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Fernandez-Llimos, F, Desselle, S, Stewart, D, Garcia-Cardenas, V, Babar, Z-U-D, Bond, C, Dago, A, Jacobsen, R, Nørgaard, LS, Polidori, C, Sanchez-Polo, M, Santos-Ramos, B, Shcherbakova, N & Tonin, FS 2023, 'Improving the quality of publications in and advancing the paradigms of clinical and social pharmacy practice research: The Granada Statements', Farmacia Hospitalaria, vol. 47, no. 3, pp. 133-138.
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Pharmacy and pharmaceutical sciences embrace a series of different disciplines. Pharmacy practice has been defined as 'the scientific discipline that studies the different aspects of the practice of pharmacy and its impact on health care systems, medicine use, and patient care'. Thus, pharmacy practice studies embrace both clinical pharmacy and social pharmacy elements. Like any other scientific discipline, clinical and social pharmacy practice disseminates research findings using scientific journals. Clinical pharmacy and social pharmacy journal editors have a role in promoting the discipline by enhancing the quality of the articles published. As has occurred in other health care areas (i.e., medicine and nursing), a group of clinical and social pharmacy practice journal editors gathered in Granada, Spain to discuss how journals could contribute to strengthening pharmacy practice as a discipline. The result of that meeting was compiled in these Granada Statements, which comprise 18 recommendations gathered into six topics: the appropriate use of terminology, impactful abstracts, the required peer reviews, journal scattering, more effective and wiser use of journal and article performance metrics, and authors' selection of the most appropriate pharmacy practice journal to submit their work.

Fernandez-Llimos, F, Desselle, S, Stewart, D, Garcia-Cardenas, V, Babar, ZUD, Bond, C, Dago, A, Jacobsen, R, Nørgaard, LS, Polidori, C, Sanchez-Polo, M, Santos-Ramos, B, Shcherbakova, N & Tonin, FS 2023, 'Improving the quality of publications in and advancing the paradigms of clinical and social pharmacy practice research: the Granada statements', Journal of Pharmaceutical Health Services Research, vol. 14, no. 3, pp. 237-243.
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Pharmacy and pharmaceutical sciences embrace a series of different disciplines. Pharmacy practice has been defined as 'the scientific discipline that studies the different aspects of the practice of pharmacy and its impact on health care systems, medicine use, and patient care'. Thus, pharmacy practice studies embrace both clinical pharmacy and social pharmacy elements. Like any other scientific discipline, clinical and social pharmacy practice disseminates research findings using scientific journals. Clinical pharmacy and social pharmacy journal editors have a role in promoting the discipline by enhancing the quality of the articles published. As has occurred in other healthcare areas (i.e. medicine and nursing), a group of clinical and social pharmacy practice journal editors gathered in Granada, Spain to discuss how journals could contribute to strengthening pharmacy practice as a discipline. The result of that meeting was compiled in these Granada Statements, which comprise 18 recommendations gathered into 6 topics, namely the appropriate use of terminology, impactful abstracts, the required peer reviews, journal scattering, more effective and wiser use of journal and article performance metrics and authors' selection of the most appropriate pharmacy practice journal to submit their work.

Ferreira, LS, Silva, MPME, Saragiotto, BT & Magalhães, MO 2023, 'Attitudes and beliefs of Brazilian physical therapists about chronic nonspecific low back pain and its impact on clinical decision-making: An Online Survey Study', Musculoskeletal Science and Practice, vol. 67, pp. 102832-102832.
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Fleming, CL, Golzan, M, Gunawan, C & McGrath, KC 2023, 'Systematic and Bibliometric Analysis of Magnetite Nanoparticles and Their Applications in (Biomedical) Research', Global Challenges, vol. 7, no. 1, pp. 2200009-2200009.
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AbstractRecent reports show air pollutant magnetite nanoparticles (MNPs) in the brains of people with Alzheimer's disease (AD). Considering various field applications of MNPs because of developments in nanotechnology, the aim of this study is to identify major trends and data gaps in research on magnetite to allow for relevant environmental and health risk assessment. Herein, a bibliometric and systematic analysis of the published magnetite literature (n = 31 567) between 1990 to 2020 is completed. Following appraisal, publications (n = 244) are grouped into four time periods with the main research theme identified for each as 1990–1997 “oxides,” 1998–2005 “ferric oxide,” 2006–2013 “pathology,” and 2014–2020 “animal model.” Magnetite formation and catalytic activity dominate the first two time periods, with the last two focusing on the exploitation of nanoparticle engineering. Japan and China have the highest number of citations for articles published. Longitudinal analysis indicates that magnetite research for the past 30 years shifted from environmental and industrial applications, to biomedical and its potential toxic effects. Therefore, whilst this study presents the research profile of different countries, the development in research on MNPs, it also reveals that further studies on the effects of MNPs on human health is much needed.

Freeman Sanderson, A 2023, 'Corrigendum to “Understanding the continuum of care in critical care: Not ABC but EBCD” [Australian Critical Care, 36 (2) 167–168]', Australian Critical Care, vol. 36, no. 3, pp. 438-438.
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Freeman-Sanderson, A 2023, 'Understanding the continuum of care in critical care: Not ABC but EBCD', Australian Critical Care, vol. 36, no. 2, pp. 167-168.
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Freeman-Sanderson, A, Crisp, J, Hodgson, CL, Holland, AE, Harrold, M, Chan, T & Tipping, CJ 2023, 'Prevalence, recovery, and factors associated with dysphagia in an older critically ill trauma cohort: A cross-sectional study', Australian Critical Care.
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Freeman-Sanderson, A, Hammond, NE, Brodsky, MB, Thompson, K & Hemsley, B 2023, 'Sepsis, critical illness, communication, swallowing and Sustainable Development Goals 3, 4, 10', International Journal of Speech-Language Pathology, vol. 25, no. 1, pp. 68-71.
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PURPOSE: Sepsis is a major global health problem with an estimated 49 million cases globally each year causing as many as 11 million deaths. The primary objective of this commentary is to describe the impacts of sepsis and critical illness on communication and swallowing function, and to discuss management strategies considering the Sustainable Development Goals (SDGs). RESULT: Communication and swallowing disabilities can occur with sepsis and critical illness. A holistic framework to optimise function, recovery, and future research priorities across the lifespan can be developed through the SDGs. CONCLUSION: Communication and swallowing disabilities following critical illness associated with sepsis have global impacts. Early multidisciplinary engagement is key to optimising individuals' function. Collaborative research, education, and public awareness is urgently needed to increase equity in health outcomes across populations. This commentary paper supports progress towards good health and well-being (SDG 3), quality education (SDG 4) and reduced inequalities (SDG 10).

Freeman-Sanderson, A, Hemsley, B, Thompson, K, Rogers, KD, Knowles, S & Hammond, NE 2023, 'Communication functions of adult patients admitted to intensive care: A multicentre, binational point prevalence study', Australian Critical Care, vol. 36, no. 6, pp. 1084-1089.
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BACKGROUND: Patient communication is profoundly impacted during the intensive care unit (ICU) stay. While the impacts of altered communication are recognised, there is a paucity of data on the prevalence of communication attempts as well as modes utilised by patients and unit practices to manage communication function. OBJECTIVE: The objectives of this study were to describe the prevalence and characteristics of observed communication attempts (nonverbal, verbal, and use of the staff call bell) in adult ICU patients and report on unit-level practices on communication management. METHODS: A prospective, binational, cross-sectional point-prevalence study was conducted across 44 Australia and New Zealand adult ICUs. Data on communication attempts, modes, ICU-level guidelines, training, and resources were collected in June 2019. RESULTS: Across 44 ICUs, 470 of 623 (75%) participants, including ventilated and nonventilated patients, were attempting to communicate on the study day. Of those invasively ventilated via an endotracheal tube for the entire study day, 42 of 172 (24%) were attempting to communicate and 39 of 45 (87%) patients with a tracheostomy were attempting to communicate. Across the cohort, the primary mode of communication was verbal communication, with 395 of 470 (84%) patients using speech; of those 371 of 395 (94%) spoke English and 24 of 395 (6%) spoke a language other than English. Participants attempting to communicate on the study day had a shorter length of stay (LOS), a mean difference of 3.8 days (95% confidence interval: 0.2; 5.1) shorter LOS in the ICU than those not attempting to communicate, and a mean difference 7.9 days (95% confidence interval: 3.1; 12.6) shorter LOS in hospital overall. Unit-level practices and supports were collected. Six of 44 (14%) ICUs had a protocol for communication management, training was available in 11 of 44 (25%) ICUs, and communication resources were available in 37 of 44 (84%) ICUs. CONCLUSION: T...

Freeman-Sanderson, A, Hemsley, B, Thompson, K, Rogers, KD, Knowles, S & Hammond, NE 2023, 'Dysphagia in adult intensive care patients: Results of a prospective, multicentre binational point prevalence study', Australian Critical Care, vol. 36, no. 6, pp. 961-966.
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Garcia-Cardenas, V, Hughes, D, Aguilar-Palacio, I, Benrimoj, SI, Rabanaque, MJ, Martinez-Martinez, F & Malo, S 2023, 'Spanish translation of the ABC taxonomy for medication adherence', Research in Social and Administrative Pharmacy, vol. 19, no. 9, pp. 1292-1297.
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Given, F, Allan, M, McCarthy, S & Hemsley, B 2023, 'Digital health autonomy for people with communication or swallowing disability and the Sustainable Development Goal 10 of reducing inequalities and Goal 3 of good health and well-being', International Journal of Speech-Language Pathology, vol. 25, no. 1, pp. 72-76.
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Purpose: The purpose of this article is to explore the Sustainable Development Goal of reduced inequalities (SDG 10) in relation to the experiences of people with communication disability with lived experiences and their access to self-determined healthcare. As such, the article also informs the goal of good health and well-being (SDG 3).Method: In preparing this article the authors reviewed recent literature on digital health records and digital autonomy as a means to improving equity of access and explored the experiences of two of the authors as people with severe communication disability who use a wide range of digital health technologies in pursuing safe and quality health care. The literature and their experiences highlight a need for improved co-design and usage across disability and health service systems management if e-health records are to be used to reduce inequalities in accessing healthcare.Result: Recent research and the lived experiences of the first two authors reflect that e-health information systems, designed to improve the consumer's ability to access and share their own health information, are not used to full advantage in disability and healthcare environments.Conclusion: Increased access to multimodal communication strategies and communication technologies, along with user-centred co-design that enables digital health autonomy will further progress towards reduced inequalities (SDG 10) and good health and well-being (SDG 3) and for people with communication or swallowing disability.

Guthrie, S, Baker, J, Cahill, J & Hemsley, B 2023, 'Mealtime difficulties in adults with mental health conditions: an integrative review', Journal of Mental Health, vol. 32, no. 2, pp. 504-516.
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BACKGROUND: Dysphagia and choking are highly prevalent in adults with mental health conditions. However, there is scant research considering the personal experience of dysphagia for this population. AIMS: To understand the evidence-base for strategies to involve the patient in recognition, assessment and treatment of mealtime difficulties. METHODS: This integrative review synthesised the literature on the experience of dysphagia in patients with mental health conditions. Patient consultation led to co-designed search terms and eligibility criteria for a systematic search of five scientific databases following Prisma guidance. Quality assessment of the eligible studies and reflexive thematic analysis were completed. RESULTS: 31 studies were included for review. These included case reports, literature reviews and cross-sectional studies. Quality of evidence was weak and no intervention studies were identified. There was scant detail regarding the personal experience of dysphagia or choking. Themes identified related to biomedical perspectives, influencing factors presented without context, and decision-making led by clinicians. CONCLUSIONS: Guidance on mental healthcare calls attention to under-diagnosis of physical co-morbidities and advocates patient inclusion. However, the patient voice in this population is rarely described regarding dysphagia. Further inclusive research is indicated to explore the impact of dysphagia and choking, and implications for interventions and outcome measures.

Harish, V, Mohd, S, Tewari, D, Pandey, NK, Vishwas, S, Babu, MR, Salkini, MA, Rehman, ZU, Alotaibi, JT, Alotaibi, RF, Alrashed, FA, Prasher, P, Sharma, N, Gupta, G, Jakhmola, V, Singh, Y, Pinto, TDJA, Paudel, KR, Mittal, N, Singh, TG, Arora, P, Dua, K & Singh, SK 2023, 'Unravelling the role of solid lipid nanoparticles in drug delivery: Journey from laboratory to clinical trial', Journal of Drug Delivery Science and Technology, vol. 85, pp. 104616-104616.
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Harrison, C, Bartley, N, Jacobs, C, Best, M, Vatter, S, Meiser, B, Ballinger, ML, Thomas, DM & Butow, P 2023, 'Family communication and results disclosure after germline sequencing: A mixed methods study', Patient Education and Counseling, vol. 114, pp. 107800-107800.
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OBJECTIVE: Research on family communication of germline genome sequencing (GS) results (versus of genetic results after targeted genetic testing) is still emerging, yet potentially complex results increase the importance of communicating risk to relatives. Promoting equity by ensuring patients have sufficient health literacy to interpret results is important in this context. This study aimed to identify cancer patients' perceived importance of result disclosure, predictors of perceptions, and perspectives on family communication. METHODS: This explanatory-sequential, cross-sectional mixed-methods study involved participants (n = 246) completing a questionnaire and (n = 20) a semi-structured interview. Ordinal logistic regressions determined associations between potential predictors and perceived importance of result disclosure. Interview transcripts were analysed thematically using a constant-comparative approach. RESULTS: More participants intended disclosing to nuclear (77.4%) than to extended family (42.7%). More than half (59.3%) felt results were family information; 62.7% believed it was important to disclose results to family members. Nuclear and extended family communication scores and education level were significantly positively associated with perceived importance of disclosure (p < 0.05). Six qualitative themes were identified: i) Responsibility to inform, ii) Choice, iii) Autonomy, iv) Family Communication, v) Significance of results, and vi) Health professional role. CONCLUSION: Low health literacy and family conflict can complicate communication of GS results. Patients seek clear, interpretable information in a format they can easily communicate. PRACTICE IMPLICATIONS: Healthcare professionals can facilitate discussion of GS results by offering written information, encouraging disclosure, exploring existing family dynamics and communication patterns, and offering strategies to improve family communication. Centralised genetic communication...

Hatoum, AH, Burton, AL & Abbott, MJ 2023, 'Validation of the revised eating disorder core beliefs questionnaire (ED-CBQ-R) in an Australian sample', Clinical Psychologist, vol. 27, no. 2, pp. 133-141.
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Hayden, JA, Ogilvie, R, Kashif, S, Singh, S, Boulos, L, Stewart, SA, Wieland, LS, Jesus-Moraleida, FR, Saragiotto, BT, Yamato, TP, de Zoete, A, Bülow, K, Almeida de Oliveira, L, Bejarano, G & Cancelliere, C 2023, 'Exercise treatments for chronic low back pain: a network meta-analysis', Cochrane Database of Systematic Reviews, vol. 2023, no. 6.
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Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. The objectives of this systematic review, conducted using a collaborative review model, are to:. Assess the effectiveness of exercise treatment (overall) in adults with chronic non-specific low back pain on important individual health outcomes: pain, functional limitations, health-related quality of life, depression, and adverse effects versus comparison treatments: (a) placebo, sham, or attention control, (b) no trial treatment (including waiting lists, control groups described as having no treatment provided, usual/normal care not controlled by the trial available to all treatment groups, or when the exercise and comparison groups receive the same co-interventions, allowing the effect of exercise treatment to be isolated), and (c) other conservative treatments (eight categories). Estimate the treatment effects and associated uncertainty for comparisons of different specific types of exercise treatment in adults with chronic non-specific low back pain to each other, and to each comparison treatment, using direct and indirect evidence with network meta-analysis. Estimate the treatment effects and associated uncertainty for comparisons of treatments composed of different exercise type categories, design, delivery, dose, and additional treatment components, and their combinations, using direct and indirect evidence with component network meta-analysis.

Hemsley, B, Darcy, S, Given, F, Murray, BR & Balandin, S 2023, 'Going thirsty for the turtles: Plastic straw bans, people with swallowing disability, and Sustainable Development Goal 14, Life Below Water', International Journal of Speech-Language Pathology, vol. 25, no. 1, pp. 15-19.
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Hussain, MS, Gupta, G, Afzal, M, Alqahtani, SM, Samuel, VP, Hassan almalki, W, Kazmi, I, Alzarea, SI, Saleem, S, Dureja, H, Singh, SK, Dua, K & Thangavelu, L 2023, 'Exploring the role of lncrna neat1 knockdown in regulating apoptosis across multiple cancer types: A review', Pathology - Research and Practice, vol. 252, pp. 154908-154908.
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Innocenti, T, Ostelo, R, Verhagen, A, Pinto, RZ, Salvioli, S, Giagio, S & Chiarotto, A 2023, 'Rehabilitation journal editors recognize the need for interventions targeted to improve the completeness of reporting, but there is heterogeneity in terms of strategies actually adopted: A cross‐sectional web‐based survey', Journal of Evidence-Based Medicine, vol. 16, no. 2, pp. 111-115.
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Iranpour, C, Wells, R, Berle, D, Saniee, A, Rostami, R, Iranpour, N & Steel, Z 2023, 'Effect of traumatic experiences and future threats on executive functioning and verbal fluency amongst Farsi-Dari speaking immigrants, refugees, and asylum seekers', Psychiatry Research Communications, vol. 3, no. 4, pp. 100146-100146.
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Ishaq, I, Mehta, P, Skinner, IW, Bagg, MK, Bier, J & Verhagen, AP 2023, 'Treatment classifications and interventions for neck pain: a scoping review', Journal of Clinical Epidemiology, vol. 159, pp. 1-9.
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OBJECTIVES: Our aim is to provide an overview of how neck pain is classified in the literature, define and group conservative interventions into 'nodes', and develop draft networks of interventions in preparation for a network meta-analysis (NMA). STUDY DESIGN AND SETTINGS: We performed a scoping review. For feasibility reasons, we searched for randomized clinical trials (RCTs) via neck pain clinical practice guidelines (CPGs) published from 2014. We used standardized data extraction forms to extract data about classification of neck pain and interventions evaluated in the included RCTs. We calculated frequencies of neck pain classifications and grouped interventions into nodes based on the definitions used in Cochrane reviews. Draft network graphs comparing interventions were constructed using the online Shiny R application CINEMA. RESULTS: We included 242 RCTs from seven CPGs, evaluating 28,581 patients. We found three different classification systems of which The Neck Pain Task Force classification was used most often. We defined and grouped all interventions into 19 discrete potential nodes. CONCLUSION: We found a wide variation in neck pain classifications and conservative interventions. Grouping the interventions was challenging and needs further evaluation before conducting a final NMA.

Iwasaki, N, Ryan, B, Worrall, L, Rose, M & Baker, C 2023, 'Experiences of mood changes and preferences for management within stepped psychological care from the perspective of spouses of people with aphasia', Aphasiology, vol. 37, no. 2, pp. 330-361.
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Jacobs, C, Turbitt, E, McEwen, A & Atkins, L 2023, 'Australasian Genetic Counselors’ Perceptions of Their Role in Supporting Clients’ Behavior Change', Journal of Personalized Medicine, vol. 13, no. 1, pp. 30-30.
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Genetic testing does not always change health behavior. Effective behavior change requires a theory-driven coordinated set of activities (behavior change techniques). Genetic counselors are ideally positioned to facilitate behavior change. We aimed to explore genetic counselors’ perceptions of their role in supporting clients’ behavior change to inform the design of an intervention. Recruitment was via a professional organization and genetics services. Data were collected from 26 genetic counselors via qualitative focus groups/interview. Transcripts were analyzed using thematic analysis and mapped to the COM-B model. We identified three behaviors genetic counselors wanted clients to change: attend appointments, access information, and share information with family members. Strategies for changing clients’ behavior included: assessing needs and capabilities, providing information and support, enabling and monitoring behavior change. Barriers included lack of behavior change skills and knowledge, lack of time, and beliefs about ownership of healthcare, directiveness of behavior change, and scope of practice. Equipping genetic counselors to deliver behavior change requires (i) education in behavior change theory and behavior change techniques, (ii) integration of capability, opportunity and motivation assessment into existing practice, and (iii) development of evidence-based strategies using behavior change tools to focus discussions and promote clients’ agency to change their behavior.

Jenkins, LC, Chang, W-J, Buscemi, V, Liston, M, Humburg, P, Nicholas, M, Graven-Nielsen, T, Hodges, PW, McAuley, JH & Schabrun, SM 2023, 'Cortical function and sensorimotor plasticity are prognostic factors associated with future low back pain after an acute episode: the Understanding persistent Pain Where it ResiDes prospective cohort study', Pain, vol. 164, no. 1, pp. 14-26.
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Abstract Predicting the development of chronic low back pain (LBP) at the time of an acute episode remains challenging. The Understanding persistent Pain Where it ResiDes study aimed to identify neurobiological and psychological risk factors for chronic LBP. Individuals with acute LBP (N = 120) participated in a prospective cohort study with 6-month follow-up. Candidate predictors were selected from the neurobiological (eg, sensorimotor cortical excitability assessed by sensory and motor-evoked potentials and brain-derived neurotrophic factor genotype), psychological (eg, depression and anxiety), symptom-related (eg, LBP history), and demographic domains. Analyses involved multivariable linear regression models with pain intensity or disability degree as continuous variables. Secondary analyses involved a multivariable logistic model with the presence of LBP at 6 months (thresholding pain intensity and disability degree) as a dichotomous variable. Lower sensory cortex and corticomotor excitability, higher baseline pain intensity, higher depression, stress, and pain catastrophizing were the strongest predictors (R 2 = 0.47) of pain intensity at 6 months. Older age and higher pain catastrophizing were the strongest predictors (R 2 = 0.30) of disability at 6 months. When the LBP outcome was dichotomised, sensory cortex and corticomotor excitability, brain-derived neurotrophic factor genotype, depression and anxiety, LBP history and baseline pain intensity, discriminated between those who did and did not report LBP at 6 months (C-statistic 0.91). This study identifies novel risk factors for the development of future LBP. Neurobiological risk factors, when added to a multivariable linear regression model, explained a further 15% of the varianc...

Johnson, C, Thout, SR, Nidhuram, S, Hart, A, Hoek, AC, Rogers, K, Shivashankar, R, Ide, N, Chatterjee, S, Webster, J & Praveen, D 2023, 'Protocol for the implementation and evaluation of a community‐based behavior change intervention to reduce dietary salt intake in India', The Journal of Clinical Hypertension, vol. 25, no. 2, pp. 175-182.
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AbstractExcess dietary salt intake is well established as a leading cause of high blood pressure and associated cardiovascular disease, yet current salt intake in India is nearly 11 g per day, more than twice World Health Organization maximum recommended intake of 5 g per day. Although dietary survey data from India indicate that the main sources of dietary salt are salt added during cooking at home, and few salt reduction efforts have focused on interventions at the household level. As a result, there is little evidence of the effectiveness of behavior change programs to reduce salt intake at the household level. The study aims to develop and implement a community based behavioral change intervention to reduce salt intake delivered by front line community‐based health volunteers; and evaluate the preliminary effectiveness, acceptability, and feasibility of delivering a salt reduction behavior change program and potential to support future scale‐up. The study is a pre‐post intervention design, and outcomes will be evaluated from a random sample of 1500 participants from 28 villages in two primary health centers in Siddipet, Telangana. Primary outcome is change in salt‐related KAB (knowledge, attitude, and behavior) score, and secondary outcomes will be changes in salt intake measured by 24 h urinary sodium excretion and change in scores using the subscales of the COM‐B (“capability”, “opportunity”, “motivation” and “behavior”) tool. Findings will be used to inform future public health policies to support implementation of scalable community‐based interventions to reduce salt intake and control hypertension, the leading‐cause of death in India.

Johnson, G, Onslow, M, Horton, S & Kefalianos, E 2023, 'Psychosocial features of stuttering for school‐age children: A systematic review', International Journal of Language & Communication Disorders, vol. 58, no. 5, pp. 1829-1845.
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AbstractBackgroundContemporary clinical and empirical perspectives indicate that management of the psychosocial features of stuttering is fundamental for effective treatment. Interventions that improve psychosocial outcomes for school‐age children who stutter are, therefore, needed.AimsThis systematic review identifies what psychosocial outcomes have been explored in existing school‐age clinical research, the measures used and the potential treatment effects. This will provide guidance for developing interventions that reflect contemporary perspectives of stuttering management.Methods & ProceduresA total of 14 databases and three conference proceedings were searched for clinical reports of psychosocial outcomes of children aged 6–12 years. The review did not include pharmacological interventions. Psychosocial measures and outcomes were analysed in each study based on data recorded pre‐treatment, immediately post‐treatment and for any follow‐up assessments.Main ContributionsOf the 4051 studies identified from the databases, a total of 22 studies met criteria for inclusion in the review. From these 22 studies, the review identified four prominent psychosocial domains that have been explored in school‐age clinical research to date: Impact of stuttering, communication attitude, anxiety and speech satisfaction. These domains vary in measurement and effect sizes. Two behavioural treatments were associated with anxiety reduction, even though they did not contain anxiolytic procedures. No evidence of potential treatment effects emerged for communication attitudes. Quality of life—an important psychosocial domain pertinent to health economics—did not feature in school‐age clinical reports.

Jukic, I, Prnjak, K, King, A, McGuigan, MR & Helms, ER 2023, 'Velocity loss is a flawed method for monitoring and prescribing resistance training volume with a free-weight back squat exercise', European Journal of Applied Physiology, vol. 123, no. 6, pp. 1343-1357.
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Abstract Purpose The aim of this study was to examine the goodness of fit, prediction accuracy, and stability of general and individual relationships between velocity loss and the percentage of completed repetitions out of maximum possible (VL-%repetitions) in the free-weight back squat exercise. The effects of sex, training status and history, as well as personality traits, on the goodness of fit and the accuracy of these relationships were also investigated. Methods Forty-six resistance-trained people (15 females and 31 males) performed a one-repetition maximum (1RM) test, and two repetitions to failure (RTF) tests, 72 h apart. RTF tests were performed with 70, 80, and 90% of 1RM with 10 min inter-set rest. Results The findings question the utility of using general and individual VL-%repetitions relationships to prescribe training volume with free-weight back squats as (1) the agreement in the %repetitions completed until reaching a given velocity loss threshold across two consecutive testing sessions was unacceptable, regardless of the load used; and (2) the ability of general and individual VL-%repetitions relationships to predict %repetitions in a subsequent testing session were poor (absolute errors > 10%). Sex, training status and history, and personality traits did not affect the goodness of fit of general and individual VL-%repetitions relationships or their prediction accuracy, suggesting potential generalisability of those findings among resistance-trained populations.

Kannaujiya, VK, De Rubis, G, Paudel, KR, Manandhar, B, Chellappan, DK, Singh, SK, MacLoughlin, R, Gupta, G, Xenaki, D, Kumar, P, Hansbro, PM, Oliver, BGG, Wich, PR & Dua, K 2023, 'Anticancer activity of NFκB decoy oligonucleotide-loaded nanoparticles against human lung cancer', Journal of Drug Delivery Science and Technology, vol. 82, pp. 104328-104328.
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Kenny, NC, Starcevic, V & Berle, D 2023, 'Associations Between Fear of Guilt and Obsessive–Compulsive Symptoms', Behaviour Change, vol. 40, no. 3, pp. 169-181.
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AbstractHalf of the people who seek treatment for Obsessive–Compulsive Disorder (OCD) do not benefit from first-line interventions. A better understanding of the factors associated with obsessions and compulsions may inform the development of more effective treatments. This study aimed to examine whether a fear of guilt is associated with obsessive–compulsive symptoms. Fear of guilt incorporates two domains: punishment (the tendency to believe that guilt means one is bad and to punish oneself for feelings of guilt) and harm prevention (the tendency to believe that guilt implies failure to be one's ideal self and the drive to prevent feelings of guilt). Online questionnaires assessing OCD symptoms, fear of guilt, and other related factors were administered to 192 adults. In contrast to previous studies, key conceptually relevant constructs, such as shame, anxiety, and depression symptoms, were also assessed. The punishment dimension of fear of guilt subscale was positively associated with OCD symptoms controlling for age, sex, guilt, shame, responsibility for harm, generalised anxiety, and depression. The punishment domain of fear of guilt may therefore be an important factor to consider and potentially target in treatments for OCD. Future investigations with clinical populations may clarify the importance of fear of guilt in OCD.

Kerwagen, F, Riemer, U, Wachter, R, von Haehling, S, Abdin, A, Böhm, M, Schulz, M & Störk, S 2023, 'Impact of the COVID-19 pandemic on implementation of novel guideline-directed medical therapies for heart failure in Germany: a nationwide retrospective analysis', The Lancet Regional Health - Europe, vol. 35, pp. 100778-100778.
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BACKGROUND: Guideline-directed medical therapy (GDMT) is the cornerstone in the treatment of patients with heart failure and reduced ejection fraction (HFrEF) and novel substances such as sacubitril/valsartan (S/V) and sodium-glucose co-transporter-2 inhibitors (SGLT2i) have demonstrated marked clinical benefits. We investigated their implementation into real-world HF care in Germany before, during, and after the COVID-19 pandemic period. METHODS: The IQVIA LRx data set is based on ∼80% of 73 million people covered by the German statutory health insurance. Prescriptions of S/V were used as a proxy for HFrEF. Time trends were analysed between Q1/2016 and Q2/2023 for prescriptions for S/V alone and in combination therapy with SGLT2i. FINDINGS: The number of patients treated with S/V increased from 5260 in Q1/2016 to 351,262 in Q2/2023. The share of patients with combination therapy grew from 0.6% (29 of 5260) to 14.2% (31,128 of 219,762) in Q2/2021, and then showed a steep surge up to 54.8% (192,429 of 351,262) in Q2/2023, coinciding with the release of the European Society of Cardiology (ESC) guidelines for HF in Q3/2021. Women and patients aged >80 years were treated less often with combined therapy than men and younger patients. With the start of the COVID-19 pandemic, the number of patients with new S/V prescriptions dropped by 17.5% within one quarter, i.e., from 26,855 in Q1/2020 to 22,145 in Q2/2020, and returned to pre-pandemic levels only in Q1/2021. INTERPRETATION: The COVID-19 pandemic was associated with a 12-month deceleration of S/V uptake in Germany. Following the release of the ESC HF guidelines, the combined prescription of S/V and SGLT2i was readily adopted. Further efforts are needed to fully implement GDMT and strengthen the resilience of healthcare systems during public health crises. FUNDING: Supported by Novartis Pharma GmbH, Nuremberg, Germany.

Kinsella, R, Nasser, A, Menz, HB, Pizzari, T, Collins, NJ & Semciw, AI 2023, 'Effects of foot orthoses and footwear interventions on impairments and quality of life in people with hip pain: A systematic review', Musculoskeletal Care, vol. 21, no. 4, pp. 1529-1550.
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AbstractBackgroundFoot orthoses and footwear interventions are advocated for the management of lower limb musculoskeletal conditions including the hip, but much of the research is focused on knee disorders. The aim of this systematic review was to synthesise the literature that investigates the use of foot orthoses or footwear in people with hip‐related pain.MethodsMEDLINE, EMBASE, CINAHL, AMED and SPORTDiscus were searched from inception to March 2023. Randomised controlled trials (RCT), cohort and pre‐post studies reporting on footwear and foot orthoses interventions, in participants with hip‐related pain, were eligible for inclusion. Outcomes included pain, physical function, and quality of life (QoL). Effect sizes were calculated where sufficient data were available. Reporting quality was assessed using the Cochrane Risk of Bias Tool (Rob‐2) and the Joanna Briggs Institute Checklist. The overall quality of evidence was rated according to the Grading of Recommendations, Assessment, Development, and Evaluations framework.ResultsOf the seven included studies (n = 266 participants), there was one RCT, one cohort and five single‐group pre‐post designs. Interventions included customised and non‐customised arch supports, heel lifts, and footwear modifications, used in the following hip conditions: trochanteric pain, non‐specific hip pain, hip osteoarthritis, and leg length dysfunction following total hip arthroplasty. Meta‐analysis was possible for outcomes in two studies, demonstrating moderate improvement in pain following foot orthoses use. Overall certainty of evidence ranged from very low to low.ConclusionSingle‐group pre‐post study designs describe positive relationships ...

Kneebone, II, Munday, I, Van Zanden, BE, Thomas, S & Newton-John, T 2023, 'Psychological interventions for post stroke pain: A systematic review', Neuropsychological Rehabilitation, vol. 33, no. 7, pp. 1304-1324.
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Chronic pain is prevalent after stroke and has a significant impact on quality of life. Research demonstrates the efficacy of psychological interventions for mixed chronic pain conditions. This review aimed to assess evidence on the effectiveness of psychological interventions for chronic pain in people with stroke. PubMed, PsychINFO, Embase, and CINAHL were searched from inception to 31 January 2021 at all levels of evidence. Psychological interventions assessing chronic pain in adults following stroke as a primary outcome were included. All outcomes related to pain quality were included (e.g., intensity, frequency, duration). Study quality was assessed using the Joanna Briggs Institute (JBI) Critical Appraisal Checklist for Case Reports and Risk of Bias in N-of-1 Trials (RoBiNT) Scale. Three single n case reports were included. A narrative synthesis was performed, indicating that psychological interventions may reduce chronic post-stroke pain; however, overall quality appraisal of the included studies was poor, owing to the low internal validity found in the single-n case report designs. The limited evidence suggests that psychological interventions may have clinical utility in reducing chronic post-stroke pain. However, owing to the paucity and quality of studies found, the results must be treated with caution. More rigorous research is needed.

Kobayashi, H & Berle, D 2023, 'The Association Between Perceived Relationship Quality and Psychological Symptoms in Refugees', Journal of Social and Clinical Psychology, vol. 42, no. 2, pp. 103-124.
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Introduction: Relationship quality plays an important role in mental health, but little is known about its importance among resettled refugees. We investigated the association between perceived relationship quality and psychological symptoms among refugees resettled in Australia. Methods: Participants were 738 adult refugees (principal applicants, 83.5% male, M = 43.2 years, SD = 12.3) and their partners who participated in the Building a New Life in Australia (BNLA) study across 5 years from 2013 to 2017. Participants were assessed for psychological distress, posttraumatic stress symptoms (PTSS), and perceived relationship quality, using the Kessler scale (K6), the Posttraumatic Stress Disorder-8 (PTSD-8), and the Dyadic Adjustment Scale-4 (DAS-4), respectively. Results: Multiple regression analyses found that, among principal applicants, perceived relationship quality predicted psychological distress (p = .0006) at post-arrival, and changes in perceived relationship quality predicted changes in PTSS (p = .0003) across a one-year interval. When partners were analyzed, results were broadly consistent with those of the principal applicants, except that changes in relationship quality did predict changes in psychological distress, but not changes in PTSS. Discussion: Relationship quality appeared to be associated with psychological distress, but improvements in relationship quality may have particular utility for reductions in posttraumatic stress disorder (PTSD) symptoms. These results highlight the importance of relationship quality as a key correlate of refugee mental health.

Kumari, V, Vishwas, S, Kumar, R, Kakoty, V, Khursheed, R, Babu, MR, Harish, V, Mittal, N, Singh, PK, Alharthi, NS, Hakami, MA, Aba Alkhayl, FF, Gupta, G, Rubis, GD, Paudel, KR, Singh, M, Zandi, M, Oliver, BG, Dua, K & Singh, SK 2023, 'An overview of biomedical applications for gold nanoparticles against lung cancer', Journal of Drug Delivery Science and Technology, vol. 86, pp. 104729-104729.
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Kumbhar, P, Kaur, J, De Rubis, G, Paudel, KR, Prasher, P, Patel, VK, Corrie, L, Chellappan, DK, Gupta, G, Singh, SK, Patravale, V, Disouza, J & Dua, K 2023, 'Inhalation drug delivery in combating pulmonary infections: Advances and challenges', Journal of Drug Delivery Science and Technology, vol. 89, pp. 105022-105022.
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Kunz, M, Götzinger, F, Jacobs, CM, Lauder, L, Ukena, C, Meyer, MR, Laufs, U, Schulz, M, Böhm, M & Mahfoud, F 2023, 'Hidden sodium in effervescent-tablet dietary supplements and over-the-counter drugs: a comparative cross-sectional study', BMJ Open, vol. 13, no. 11, pp. e076302-e076302.
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ObjectiveDietary sodium intake represents a risk factor for cardiovascular disease and mortality. The study sought to analyse the sodium content of effervescent dietary supplements and drugs in Germany and the USA.DesignComparative cross-sectional study.Setting and methodsThe sodium content of 39 dietary supplement effervescent tablets available in Germany was measured in May and June 2022 using optical emission spectrometry with inductively coupled argon plasma. The sodium content of 33 common pharmacy-only effervescent tablets (over-the-counter (OTC) drugs) in Germany was obtained from the summary of product characteristics. We compared the sodium content of the measured German dietary supplement effervescent tablets to that of 51 dietary supplement effervescent tablets available in the USA (data: National Institutes of Health’s Dietary Supplement Label Database).ResultsThe measured sodium content in the German dietary supplements was 283.9±122.6 mg sodium/tablet, equivalent to 14±6% of the maximum recommended daily sodium intake (MRDSI). Vitamin products had the highest (378.3±112.8 mg, 19±6% of MRDSI), and calcium products had the lowest mean sodium content (170.4±113.2 mg, 9±6% of MRDSI). Vitamin products contained significantly more sodium than magnesium (378.3 mg vs 232.7 mg; p=0.004), calcium (378.3 mg vs 170.4 mg; p=0.006) and mineral products (378.3 mg vs 191.6 mg; p=0.048). The sodium content measured in products available in Germany was higher when compared with the declared sodium content on the label of the products sold in the USA (283.9 mg vs 190.0 mg; p<0.001). The median summary of product characteristics-declared sodium content of a single dose of the German OTC drugs was 157.0 mg (IQR: 98.9–417.3 mg); p...

Laird, C, Benson, H & Williams, KA 2023, 'Pharmacist interventions in osteoporosis management: a systematic review', Osteoporosis International, vol. 34, no. 2, pp. 239-254.
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Laird, C, Williams, KA & Benson, H 2023, 'Perceptions and practices of aged care pharmacists regarding osteoporosis management: a qualitative study', International Journal of Clinical Pharmacy, vol. 45, no. 4, pp. 913-921.
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Abstract Background Osteoporosis is a common but sub-optimally managed disease among aged care residents. Although pharmacists are one of the key healthcare providers responsible for osteoporosis medication management there is limited research on their involvement. Aim This study explored the perceptions and practices of Australian pharmacists regarding osteoporosis management for aged care residents. Method Semi-structured interviews were conducted with aged care pharmacists. Interviews were recorded, transcribed, and analysed using a constructivist grounded theory approach. Results Twenty-one aged care pharmacists were interviewed. Three main themes were identified: osteoporosis is highly prevalent but given low priority, factors affecting pharmacists’ management of osteoporosis, and optimism for the future role of pharmacists in osteoporosis management. The complexity of aged care residents’ healthcare needs and the silent, insidious nature of osteoporosis contribute to the low priority it is afforded. Barriers identified by pharmacists included their current practice model, limited access to residents’ medical histories and difficulties accessing bone mineral density (BMD) testing. Interdisciplinary collaboration and education regarding osteoporosis management were seen as facilitators. Pharmacists were optimistic that an embedded practice model would improve their capacity to influence osteoporosis management. Conclusion

Lazarus, B, Kotwal, S, Gallagher, M, Gray, NA, Coggan, S, Rogers, K, Talaulikar, G & Polkinghorne, KR 2023, 'Effect of a Multifaceted Intervention on the Incidence of Hemodialysis Catheter Dysfunction in a National Stepped-Wedge Cluster Randomized Trial', Kidney International Reports, vol. 8, no. 10, pp. 1941-1950.
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Introduction: Effective strategies to prevent hemodialysis (HD) catheter dysfunction are lacking and there is wide variation in practice. Methods: In this post hoc analysis of the REDUcing the burden of dialysis Catheter ComplicaTIOns: a national (REDUCCTION) stepped-wedge cluster randomized trial, encompassing 37 Australian nephrology services, 6361 participants, and 9872 catheters, we investigated whether the trial intervention, which promoted a suite of evidence-based practices for HD catheter insertion and management, reduced the incidence of catheter dysfunction, which is defined by catheter removal due to inadequate dialysis blood flow. We also analyzed outcomes among tunneled cuffed catheters and sources of event variability. Results: A total of 873 HD catheters were removed because of dysfunction over 1.12 million catheter days. The raw incidence was 0.91 events per 1000 catheter days during the baseline phase and 0.68 events per 1000 catheter days during the intervention phase. The service-wide incidence of catheter dysfunction was 33% lower during the intervention after adjustment for calendar time (incidence rate ratio = 0.67; 95% confidence interval [CI], 0.50–0.89; P = 0.006). Results were consistent among tunneled cuffed catheters (adjusted incidence rate ratio = 0.68; 95% CI, 0.49–0.94), which accounted for 75% of catheters (n = 7403), 97.4% of catheter exposure time and 88.2% of events (n = 770). Among tunneled catheters that survived for 6 months (21.5% of tunneled catheters), between 2% and 5% of the unexplained variation in the number of catheter dysfunction events was attributable to service-level differences, and 18% to 36% was attributable to patient-level differences. Conclusion: Multifaceted interventions that promote evidence-based catheter care may prevent dysfunction, and patient factors are an important source of variation in events.

Liu, CTX, Menzies, RE & Menzies, RG 2023, 'A Systematic Review of Existential Concerns in Borderline Personality Disorder', Journal of Humanistic Psychology, pp. 002216782311657-002216782311657.
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Background: Existential philosophy and psychotherapy focuses on the “givens” of human experience, including feelings of meaninglessness, isolation, death anxiety, and concerns surrounding identity and freedom. Although borderline personality disorder (BPD) is arguably characterized by issues in a number of these domains, it has not been systematically examined through the lens of existential therapy. Method: The current systematic review included 37 articles which examined existential concerns in relation to BPD. Results: These articles highlighted the predominance of chronic identity and isolation-related concerns in BPD, as well as the potential role of meaning in buffering against the distress of BPD, such as suicidality and comorbid depressive features. Implications: The implications of existential phenomenological findings in the conceptualization of BPD, treatment and future existential research are discussed.

Lo, D, Waite, M & Rose, TA 2023, 'Experiences of childhood stroke and aphasia during adolescence: An analysis of YouTube videos', International Journal of Speech-Language Pathology, vol. 25, no. 3, pp. 403-412.
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Loomes, M, Tran, DMD, Chowdhury, NS, Birney, DP, Harris, JA & Livesey, EJ 2023, 'Is cortical inhibition in primary motor cortex related to executive control?', Cortex, vol. 160, pp. 100-114.
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Lowe, R, Menzies, R, O'Brian, S, Onslow, M & Packman, A 2023, 'Supporting a student who stutters: What schools can do', Scan, vol. 42, no. 1, pp. 53-56.

Ludlow, K, Russell, JK, Ryan, B, Brown, RL, Joynt, T, Uhlmann, LR, Smith, GE, Donovan, C, Hides, L, Spence, SH, March, S & Cobham, VE 2023, 'Co-designing a digital mental health platform, “Momentum”, with young people aged 7–17: A qualitative study', DIGITAL HEALTH, vol. 9.
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Introduction Digital mental health interventions (DMHIs) offer a promising alternative or adjunct treatment method to face-to-face treatment, overcoming barriers associated with stigma, access, and cost. This project is embedded in user experience and co-design to enhance the potential acceptability, usability and integration of digital platforms into youth mental health services. Objective To co-design a digital mental health platform that provides self-directed, tailored, and modularised treatment for young people aged 7–17 years experiencing anxiety, depression and other related problems. Methods Sixty-eight participants, aged 7–17 years, engaged in one of 20 co-design workshops. Eight workshops involved children (n  =  26, m  =  9.42 years, sd  =  1.27) and 12 involved adolescents (n  =  42, m  =  14.57 years, sd  =  1.89). Participants engaged in a variety of co-design activities (e.g., designing a website home page and rating self-report assessment features). Workshop transcripts and artefacts (e.g., participants’ drawings) were thematically analysed using Gale et al.'s Framework Method in NVivo. Results Six themes were identified: Interactive; Relatable; Customisable; Intuitive; Inclusive; and Personalised, transparent and trustworthy content. The analysis revealed differences between children's and adolescents’ designs and ideas, supporting the need for two different versions of the platform, with age-appropriate activities, features, terminology, and content. Conclusions This research showcased co-design as a powerful tool to facilitate collaboration with young people in designing DMHIs. Two sets of recommendations were produced: 1) recommendations for th...

Machado, FLDS, Cañás, M, Doubova, SV, Urtasun, MA, Marín, GH, Osorio-de-Castro, CGS, Albuquerque, FC, Ribeiro, TB, Pont, L, Crisóstomo Landeros, J, Roldán Saelzer, J, Sepúlveda Viveros, D, Acosta, A, Machado Beltrán, MA, Gordillo Alas, LI, Orellana Tablas, LA, Benko, R, Convertino, I, Bonaso, M, Tuccori, M, Kirchmayer, U, Contreras Sánchez, SE, Rodríguez-Tanta, LY, Gutierrez Aures, Y, Lin, B, Alipour-Haris, G, Eworuke, E & Lopes, LC 2023, 'Biosimilars approvals by thirteen regulatory authorities: A cross-national comparison', Regulatory Toxicology and Pharmacology, vol. 144, pp. 105485-105485.
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Maguire, PN, Bhullar, N, Cosh, SM & Wootton, BM 2023, 'Feasibility and acceptability of a remotely delivered transdiagnostic CBT treatment for postnatal anxiety and related disorders: A pilot case series', Women's Health, vol. 19, pp. 174550572311758-174550572311758.
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Women in the postnatal period are at a high risk of developing clinically significant symptoms of anxiety. Cognitive behavioural therapy is effective in the treatment of postnatal anxiety; however, there are many barriers to accessing this treatment. This study examined the feasibility and acceptability of transdiagnostic cognitive behavioural therapy delivered remotely via Internet videoconferencing. Three women ( Mage = 28.33 years; SD = 4.04) with a postnatal anxiety-related disorder were treated using the videoconference-delivered cognitive behavioural therapy. The treatment was delivered once per week over a 5-week period. All participants met criteria for clinically significant change in anxiety symptoms at post-treatment, and one participant met criteria for clinically significant change in depressive symptoms, which was maintained at 3-month follow-up. The intervention was also found to be acceptable by participants. The results provide preliminary feasibility evidence of the clinical utility and acceptability of remotely delivered transdiagnostic cognitive behavioural therapy as an intervention for postnatal anxiety disorders.

Maguire, PN, Bhullar, N, Cosh, SM & Wootton, BM 2023, 'Help-seeking and treatment delivery preferences for women experiencing perinatal anxiety symptoms', Behavioural and Cognitive Psychotherapy, vol. 51, no. 4, pp. 271-285.
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AbstractBackground:Anxiety is common during the perinatal period and despite effective treatments being available, many women with perinatal anxiety disorders experience barriers when accessing treatment.Aims:The aims of the current study were to explore women’s perceived barriers to treatment uptake; cognitive behavioural therapy (CBT) treatment delivery preferences; and the utility of the Health Belief Model (HBM) in predicting intention to seek psychological help for women with perinatal anxiety symptoms.Method:This study employed a cross-sectional design consisting of women with self-reported anxiety in the perinatal period. A total of 216 women (Mage=28.53 years;SD=4.97) participated in the study by completing a battery of online self-report measures.Results:The results indicated that the most salient barriers to accessing care were: (1) the cost of treatment, (2) wanting to solve the problem on their own, and (3) thinking the problem would go away without treatment. Group-delivered CBT was the least acceptable treatment method, while face-to-face individual CBT was the most acceptable treatment method. The HBM variables predicted approximately 35% of the variance in help-seeking intention.Discussion:This study has important implications for the delivery of psychological care in the perinatal period and may be used to improve treatment uptake.

Mahfoud, F, Kieble, M, Enners, S, Kintscher, U, Laufs, U, Böhm, M & Schulz, M 2023, 'Use of fixed-dose combination antihypertensives in Germany between 2016 and 2020: an example of guideline inertia', Clinical Research in Cardiology, vol. 112, no. 2, pp. 197-202.
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Abstract Background The 2018 European Society of Cardiology (ESC)/European Society of Hypertension (ESH) guidelines for the management of hypertension highlight the importance of fixed-dose combinations (FDC) for the treatment of hypertension and recommend initial single-pill combination therapy in almost all patients. However, data on the implementation of these recommendations in clinical practice are scarce. Methods Data from the German Institute for Drug Use Evaluation (DAPI) were analyzed and extrapolated accounting for approximately 88% of Germany’s population (approximately 73.3 million subjects). All antihypertensive (AHT) FDC products available on the German market were included in the analyses. We examined the time course of dispensed packages between January 2016 and December 2020. Results FDCs accounted for 15.4% of all AHT in 2016 and for 10.9% in 2020. While dispensing of all AHT increased slightly from year to year (2016: 143.8 million, 2020: 153.2 million packs), dispensing of FDCs decreased from 22.2 million (2016) to 16.6 million (2020) packs. Dispensing of FDCs containing hydrochlorothiazide (HCT) declined considerably from 2016 to 2020 (Q1 2016: 4.65 million, Q4 2020: 3.13 million packs). Accordingly, the proportion of HCT-containing combinations in all FDCs decreased from 85.3 to 74.2% from Q1 2016 to Q4 2020. Patients younger than 80 years were prescribed FDCs more frequently (14.6% of all AHT, based on the entire evaluation period) than patients 80 years and older (10.0%). In both age groups, this proportion decreased continuously over time. ...

Malik, R, Paudel, KR, Manandhar, B, De Rubis, G, Shen, J, Mujwar, S, Singh, TG, Singh, SK, Gupta, G, Adams, J, MacLoughlin, R, Oliver, BGG, Hansbro, PM, Chellappan, DK & Dua, K 2023, 'Agarwood oil nanoemulsion counteracts LPS-induced inflammation and oxidative stress in RAW264.7 mouse macrophages', Pathology - Research and Practice, vol. 251, pp. 154895-154895.
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Malyla, V, De Rubis, G, Paudel, KR, Chellappan, DK, Hansbro, NG, Hansbro, PM & Dua, K 2023, 'Berberine nanostructures attenuate ß-catenin, a key component of epithelial mesenchymal transition in lung adenocarcinoma', Naunyn-Schmiedeberg's Archives of Pharmacology, vol. 396, no. 12, pp. 3595-3603.
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AbstractLung cancer (LC) is the leading cause of cancer-related deaths globally. It accounts for more than 1.9 million cases each year due to its complex and poorly understood molecular mechanisms that result in unregulated cell proliferation and metastasis. β-Catenin is a developmentally active protein that controls cell proliferation, metastasis, polarity and cell fate during homeostasis and aids in cancer progression via epithelial–mesenchymal transition. Therefore, inhibition of the β-catenin pathway could attenuate the progression of LC. Berberine, an isoquinoline alkaloid which is known for its anti-cancer and anti-inflammatory properties, demonstrates poor solubility and bioavailability. In our study, we have encapsulated berberine into liquid crystalline nanoparticles to improve its physiochemical functions and studied if these nanoparticles target the β-catenin pathway to inhibit the human lung adenocarcinoma cell line (A549) at both gene and protein levels. We observed for the first time that berberine liquid crystalline nanoparticles at 5 µM significantly attenuate the expression of the β-catenin gene and protein. The interaction between berberine and β-catenin was further validated by molecular simulation studies. Targeting β-catenin with berberine nanoparticles represents a promising strategy for the management of lung cancer progression.

Malyla, V, Paudel, KR, De Rubis, G, Hansbro, NG, Hansbro, PM & Dua, K 2023, 'Cigarette smoking induces lung cancer tumorigenesis via upregulation of the WNT/β-catenin signaling pathway', Life Sciences, vol. 326, pp. 121787-121787.
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Mankelow, J, Ravindran, D, Graham, A, Suri, S, Pate, JW, Ryan, CG & Martin, D 2023, 'An evaluation of a one-day pain science education event in a high school setting targeting pain related beliefs, knowledge, and behavioural intentions', Musculoskeletal Science and Practice, vol. 66, pp. 102818-102818.
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BACKGROUND: Persistent pain is a common condition affecting one in four UK adults. Public understanding of pain is limited. Delivering pain education within schools may improve public understanding in the longer term. OBJECTIVE: To evaluate the impact of a one-day Pain Science Education (PSE) event on sixth form/high school students' pain beliefs, knowledge and behavioural intention. METHODS: Exploratory, single-site, mixed-methods, single-arm study involving secondary school students ≥16 years old attending a one-day PSE event. Outcome measures included the Pain Beliefs Questionnaire (PBQ), Concepts of Pain Inventory (COPI-ADULT), a vignette to assess pain behaviours; and thematic analysis of semi-structured interviews. RESULTS: Ninety (mean age 16.5 years, 74% female) of the 114 attendees, agreed to participate in the evaluation. PBQ scores improved on the Organic beliefs subscale [mean difference -5.9 (95% CI -6.8, -5.0), P < 0.01] and Psychosocial Beliefs subscale [1.6 (1.0, 2.2) P < 0.01]. The COPI-Adult revealed an improvement [7.1 (6.0-8.1) points, P < 0.01] between baseline and post intervention. Pain behavioural intentions improved post education for work, exercise, and bed rest related activities (p < 0.05). Thematic analysis of interviews (n = 3) identified increased awareness of chronic pain and its underpinning biology, beliefs that pain education should be widely available, and that pain management should be holistic. CONCLUSIONS: A one-day PSE public health event can improve pain beliefs, knowledge and behavioural intentions in high school students and increase openness to holistic management. Future controlled studies are needed to confirm these results and investigate potential long-term impacts.

Martínez‐Mardones, F, Benrimoj, SI, Ahumada‐Canale, A, Plaza‐Plaza, JC & Garcia‐Cardenas, V 2023, 'BC Clinical impact of medication reviews with follow‐up in cardiovascular older patients in primary care: A cluster‐randomized controlled trial', British Journal of Clinical Pharmacology, vol. 89, no. 7, pp. 2131-2143.
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AimsCardiovascular diseases (CVD) are the primary cause of death in Chile. Pharmacist‐led medication review with follow‐up (MRF) has improved CVD risk factors control in Europe and North America. However, their healthcare systems differ from Chile's, precluding generalizability. This trial aimed to determine the effect of MRF on CVD risk factor control among older patients with polypharmacy attending public primary care centres in Chile.MethodsA cluster‐randomized controlled trial was conducted in 24 centres. Patients older than 65 years with moderate‐to‐high CVD risk, five or more medications, hypertension, type 2 diabetes or dyslipidaemia, received MRF in addition to usual care or usual care alone for 12 months. Primary outcome measures were clinical goal achievement for hypertension, type 2 diabetes and dyslipidaemia, as well as medication adherence, medication number and CVD risk score. Adjusted generalized estimating equations were used, with odds ratios (ORs) for binary measures and mean differences for continuous measures.ResultsIn total, 324 patients from 12 centres (174 MRF group, 150 usual care group, six centres each) received four pharmacist visits. Significant improvements were found for goal achievement in hypertension (OR 4.37, 95% confidence interval [CI] 2.54 to 7.51, P = .001), LDL cholesterol (OR 3.67, 95% CI 2.13 to 6.33, P = .001), type 2 diabetes (OR 6.97, 95% CI 3.69 to 13.2, P = .001), medication adherence (OR 6.60, 95% CI 1.36 to 31.9, P = .022), medications number (−0.86, 95% CI −1.14 to −0.58, P < .001) and CVD risk score (−2.27, 95% CI −2.84 to −1.69, P < .001).

McAloon, J & de la Poer Beresford, K 2023, 'Online Behavioral Parenting Interventions for Disruptive Behavioral Disorders: A PRISMA Based Systematic Review of Clinical Trials', Child Psychiatry & Human Development, vol. 54, no. 2, pp. 379-396.
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Behavioral Parenting Interventions (BPIs) are efficacious, evidence-based interventions for Disruptive Behavioral Disorders in children. Technological advances have seen online adaptations of BPIs further increase efficacy and expand program reach. This systematic review examined the treatment outcomes of online BPIs. Our secondary aim was to examine which components of online BPIs are associated with beneficial child outcomes. Electronic databases were searched to identify randomized controlled trials of online BPIs for children with disruptive behavioral difficulties published between 2000 and 2020. 10 studies, reporting on 9 different interventions, met inclusion criteria. The review indicated online BPIs are a viable treatment for Disruptive Behavioral Disorders with 9 of 10 reporting significant improvements post-treatment. Effective interventions had clearly defined program structure and included content based on operant learning principles. Future research would benefit from greater detail when reporting intervention content, and regular assessment of progress through treatment against the delivery of specific program components.

McDonald, S, Melkonian, M, Karin, E, Dear, BF, Titov, N & Wootton, BM 2023, 'Predictors of response to cognitive behavioural therapy (CBT) for individuals with obsessive-compulsive disorder (OCD): a systematic review', Behavioural and Cognitive Psychotherapy, vol. 51, no. 4, pp. 302-319.
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AbstractBackground:Cognitive behavioural therapy (CBT) is considered the first-line treatment for obsessive-compulsive disorder (OCD). However, some individuals with OCD remain symptomatic following CBT, and therefore understanding predictors of outcome is important for informing treatment recommendations.Aims:The current study aimed to provide the first synthesis of predictors of outcome following CBT for OCD in adults with a primary diagnosis of OCD, as classified by DSM-5.Method:Eight studies (n=359; mean age range=29.2–37.7 years; 55.4% female) were included in the systematic review.Results:Congruent with past reviews, there was great heterogeneity of predictors measured across the included studies. Therefore, a narrative synthesis of findings was conducted. Findings from this systematic review indicated that some OCD-related pre-treatment variables (i.e. pre-treatment severity, past CBT treatment, and levels of avoidance) and during treatment variables (i.e. poor working alliance and low treatment adherence) may be important to consider when making treatment recommendations. However, the results also indicate that demographic variables and psychological co-morbidities may not be specific predictors of treatment response.Conclusions:These findings add to the growing body of literature on predictors of CBT treatment outcomes for individuals with OCD.

McGrath, LR, Oey, L, McDonald, S, Berle, D & Wootton, BM 2023, 'Prevalence of body dysmorphic disorder: A systematic review and meta-analysis', Body Image, vol. 46, pp. 202-211.
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Body dysmorphic disorder (BDD) is characterised by a preoccupation with a perceived defect in appearance. This preoccupation results in the completion of repetitive/time consuming behaviours to reduce distress. While the disorder results in considerable distress and impairment, the prevalence of the disorder is largely unknown, as BDD has not been examined in large epidemiological studies. The aim of the current study was to provide an estimate of BDD prevalence in a variety of settings using a meta-analytic approach using only studies that have made a diagnosis using a structured diagnostic interview. Twenty-two studies met criteria (n = 7159) and the pooled point-prevalence estimate for BDD was 11.3% across all studies with high levels of heterogeneity (I2 = 95.81). The pooled point-prevalence estimate was 20.0% in cosmetic/dermatology settings, 7.4% in mental health settings, and 6.7% in 'other' settings (including students and professional ballet dancers). The risk of bias assessment indicated questionable methodological quality in some of the included studies. While this study provides an important improvement on the existing literature there is a need to include BDD in epidemiological studies in order to have a more accurate understanding of the prevalence rate of this mental health condition in the community.

McInerney-Leo, AM, Ayres, S, Boyle, J, Jacobs, C & Newson, AJ 2023, 'Human Genetics Society of Australasia Position Statement: Genetic Testing and Personal Insurance Products in Australia', Twin Research and Human Genetics, vol. 26, no. 2, pp. 184-187.
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AbstractThe expansion of genetic and genomic testing in clinical practice and research, and the growing market for direct-to-consumer genomic testing has led to increased awareness about the impact of this form of testing on insurance. Genetic or genomic information can be requested by providers of mutually rated insurance products, who may then use it when setting premiums or determining eligibility for cover under a particular product. Australian insurers are subject to relevant legislation and an industry led standard that was updated in 2019 to introduce a moratorium on the use of genetic test results in life insurance underwriting for policies <AU$500K. The Human Genetics Society of Australasia has updated its position statement on genetic testing and life insurance to account for these changes and to increase the scope of the statement to include a wider range of personally-rated insurance products, such as life, critical care, and income protection products. Recommendations include that: providers of professional education involving genetics should include ethical, legal, and social aspects of insurance discrimination in their curricula; the Australian Government take a more active role in regulating use of genetic information in personal insurance; that information obtained in the course of a research project be excluded; insurers seek expert advice when making underwriting decisions regarding genetic testing; and engagement between the insurance industry, regulators, and the genetics profession be improved.

McInerney-Leo, AM, Ayres, S, Boyle, J, Jacobs, C & Newson, AJ 2023, 'Human Genetics Society of Australasia Position Statement: Genetic Testing and Personal Insurance Products in Australia – CORRIGENDUM', Twin Research and Human Genetics, pp. 1-1.
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Mendonca, CJ, Newton-John, TRO, Alperstein, DM, Begley, K, Hennessy, RM & Bulsara, SM 2023, 'Quality of Life of People Living with HIV in Australia: The Role of Stigma, Social Disconnection and Mental Health', AIDS and Behavior, vol. 27, no. 2, pp. 545-557.
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AbstractHIV is a manageable chronic illness, due to advances in biomedical management. However, many people living with HIV (PLHIV) continue to experience psychosocial challenges, which have been associated with poorer quality of life (QoL). This study aimed to explore how psychosocial factors contributed to the QoL of PLHIV in Australia; specifically, the relationship between HIV-related stigma, social connectedness, mental health, and QoL. Participants were 122 PLHIV attending The Albion Centre (a tertiary HIV clinic in Sydney, Australia), who completed questionnaires which measured HIV-related stigma, social support, mental health symptomology and QoL. Results indicated that HIV-related stigma predicted poorer QoL, as did mental health symptomology. Conversely, social connectedness improved QoL. Additionally, social connectedness was found to mediate the relationship between HIV-related stigma and QoL, whereas the hypothesized moderating role of mental health symptomology on this model was not significant. These findings provide insight into the impact of psychosocial factors on QoL, offering practitioners various points of clinical intervention.

Menzies, RE & Menzies, RG 2023, 'Death anxiety and mental health: Requiem for a dreamer', Journal of Behavior Therapy and Experimental Psychiatry, vol. 78, pp. 101807-101807.
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Recently, there has been an increased interest in the role of death anxiety in a broad range of mental health disorders. It has been argued that the fear of death may be a transdiagnostic variable contributing to the development and maintenance of many chronic mental health problems. Further, it has been suggested that death anxiety may be responsible for relapse and the emergence of new disorders in patients that have received successful treatment for earlier conditions in their lives. Given this, the purpose of the present selective review is to: (1) explore contemporary theoretical accounts of the role of death anxiety in a broad range of human behaviours; (2) examine evidence for death anxiety as a key variable in mental health disorders; (3) examine evidence on the treatment of death anxiety in both non-clinical and clinical populations; (4) describe the limitations of the current literature, and; (5) provide a detailed description of the critical future directions for this field.

Menzies, RE, Julien, A, Sharpe, L, Menzies, RG, Helgadóttir, FD & Dar-Nimrod, I 2023, 'Overcoming death anxiety: a phase I trial of an online CBT program in a clinical sample', Behavioural and Cognitive Psychotherapy, vol. 51, no. 4, pp. 374-379.
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AbstractBackground:Growing research indicates that death anxiety is implicated in many mental health conditions. This increasing evidence highlights a need for scalable, accessible and cost-effective psychological interventions to reduce death anxiety.Aims:The present study outlines the results of a phase I trial for one such treatment: Overcome Death Anxiety (ODA). ODA is the first CBT-based online intervention for fears of death, and is an individualised program requiring no therapist guidance.Method:A sample of 20 individuals with various mental health diagnoses commenced the ODA program. Death anxiety was assessed at baseline and at post-intervention. Depression, anxiety and stress were also measured.Results:In total, 50% (10/20) reached the end of the program and completed post-treatment questionnaires. Of these, 60% (6/10) showed a clinically reliable reduction in their overall death anxiety, and 90% (9/10) showed a reduction on at least one facet of death anxiety. There were no adverse events noted.Conclusions:ODA appears to be a safe and potentially effective treatment for death anxiety. The findings have provided initial evidence to support a randomised controlled trial using a larger sample, to further examine the efficacy of ODA.

Miao, M, Debono, D, Power, E, Rietdijk, R, Brunner, M & Togher, L 2023, 'Digital Health Interventions for Adults with Acquired Brain Injury and Their Close Others: Implementation, Scalability, and Sustainability in the COVID-19 Context', Stud Health Technol Inform, vol. 304, pp. 96-100.
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The Social Brain Toolkit is a novel suite of web-based interventions to support people with acquired brain injury and their close others with communication difficulties post-injury. The aim of this study was to investigate potential impacts of the Toolkit’s wider political, economic, regulatory, professional, and sociocultural context on its implementation, scalability, and sustainability. Nine people with academic, healthcare or industry experience implementing digital health interventions prior to and during COVID-19 were individually interviewed. Data were deductively analysed according to the Non-adoption, Abandonment, Scaleup, Spread and Sustainability framework, with a focus on the domain of the ‘Wider system’. Results indicated that COVID-19 facilitated a pivot to virtual care models which was timely for the implementation of the Social Brain Toolkit; political and economic changes were entwined; and risk management, data compliance and governance were key considerations for healthcare professionals and organisations.

Miao, M, Morrow, R, Salomon, A, Mcculloch, B, Evain, J-C, Wright, MR, Murphy, MT, Welsh, M, Williams, L, Power, E, Rietdijk, R, Debono, D, Brunner, M & Togher, L 2023, 'Digital Health Implementation Strategies Coproduced With Adults With Acquired Brain Injury, Their Close Others, and Clinicians: Mixed Methods Study With Collaborative Autoethnography and Network Analysis', Journal of Medical Internet Research, vol. 25, pp. e46396-e46396.
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Background Acquired brain injuries (ABIs), such as stroke and traumatic brain injury, commonly cause cognitive-communication disorders, in which underlying cognitive difficulties also impair communication. As communication is an exchange with others, close others such as family and friends also experience the impact of cognitive-communication impairment. It is therefore an internationally recommended best practice for speech-language pathologists to provide communication support to both people with ABI and the people who communicate with them. Current research also identifies a need for neurorehabilitation professionals to support digital communication, such as social media use, after ABI. However, with >135 million people worldwide affected by ABI, alternate and supplementary service delivery models are needed to meet these communication needs. The “Social Brain Toolkit” is a novel suite of 3 interventions to deliver communication rehabilitation via the internet. However, digital health implementation is complex, and minimal guidance exists for ABI. Objective This study aimed to support the implementation of the Social Brain Toolkit by coproducing implementation knowledge with people with ABI, people who communicate with people with ABI, clinicians, and leaders in digital health implementation. Methods A maximum variation sample (N=35) of individuals with living experience of ABI, close others, clinicians, and digital health implementation leaders participated in an explanatory sequential mixed methods design. Stakeholders quantitatively prioritized 4 of the 7 theoretical domains of the Nonadoption, Abandonment, Scale-up, Spread, and Sustainability (NASSS) framework as...

Mitchell, LA, Jacobs, C & McEwen, A 2023, '(In)visibility of LGBTQIA+ people and relationships in healthcare: A scoping review', Patient Education and Counseling, vol. 114, pp. 107828-107828.
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OBJECTIVE: To identify and map research into the visibility of LGBTQIA+ people and their relationships in healthcare, with the view to inform future research and practice. METHOD: Five databases were systematically searched for published and grey literature. Primary research reporting on visibility of LGBTQIA+ people in healthcare was included. Two reviewers independently screened the studies until an acceptable level of agreement was reached. A narrative synthesis was conducted and findings mapped to a taxonomy of microaggressions involving three sub-categories: microinsults, microassaults and microinvalidations. RESULTS: The microaggressions identified included Microinsults: 'Perception of health professionals' knowledge and comfort' and 'Disclosure'; Microassaults: 'Discrimination and stigma'; Microvalidations: 'Accessing and navigating through services', 'Encounters of assumptions and stereotypes', 'Validating identities and including relationships', and 'Reading the environment'. CONCLUSION: Despite growing societal acceptance, microaggressions still exist within healthcare. Groups within LGBTQIA+ communities have varying levels of visibility in research and healthcare based on the studies included. PRACTICE IMPLICATIONS: The limited visibility of LGBT and lack of visibility of QIA+ people and their relationships in healthcare highlight the need to include the views of all LGBTQIA+ communities in research, and to ensure health professionals and clinical services are equipped to address this (in)visibility gap.

Morriss, M & Berle, D 2023, 'Measuring Moral Injury: Further Validation of the MIES-C and EMIS-C in a Civilian Population', Journal of Psychopathology and Behavioral Assessment, vol. 45, no. 4, pp. 1046-1058.
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AbstractMoral injury among civilians has garnered increased recognition in recent years. However, most moral injury measures have focused on military experiences, with language being military specific. This study aimed to further validate two self-report measures of civilian moral injury, the Moral Injury Events Scale - Civilian (MIES-C) and Expressions of Moral Injury Scale - Civilian (EMIS-C). Participants were 312 adults (99 males, 212 females, Mage = 37.24) who completed the MIES-C, EMIS-C, and a battery of associated measures on two occasions. For the MIES-C, four Confirmatory Factor Analysis (CFA) models were examined. A three-factor model, with covaried items, provided the best fit to the data. For the EMIS-C, three CFAs were examined. A two-factor model, with covaried items, and the bi-factor model provided the best fit to the data, with the two-factor model being preferred for reasons of parsimony and its absence of weak and negative item loadings. Both measures demonstrated acceptable test-retest reliability and convergent validity with associated measures of psychological distress. This study provides psychometrically sound tools for clinicians and researchers of civilian moral injury.

Mortlock, R, Smith, V, Nesci, I, Bertoldi, A, Ho, A, El Mekkawi, Z, Kakuzada, L, Williams, K, Pont, L, De Rubis, G & Dua, K 2023, 'A comparative evaluation of propranolol pharmacokinetics in obese versus ideal weight individuals: A blueprint towards a personalised medicine', Chemico-Biological Interactions, vol. 371, pp. 110351-110351.
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Munday, I, Newton-John, T & Kneebone, I 2023, 'Clinician experience of metaphor in chronic pain communication', Scandinavian Journal of Pain, vol. 23, no. 1, pp. 88-96.
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Abstract Objectives This study investigated clinician experience of patient use of metaphors in chronic pain communication. Methods Interviews were conducted with eighteen Australian clinicians working with chronic pain patients, age range 26–64 years (M=46.6), 50% female, experience working in chronic pain ranging from 2 to 27 years (M=11.16). Results Thematic Analysis yielded four key themes: Metaphor as communicative tool, Metaphor as clue, Metaphor as obstacle, and Metaphor use in treatment. Clinicians identified metaphor as an important tool for patients to communicate their pain experience, whilst acknowledging that it could at times be unhelpful to patients. Metaphor was seen to contain useful information for clinicians and possess utility in assessment and treatment. Conclusions Metaphors play a significant role in chronic pain consultations, enabling clinician insight into pain type, psychopathology, and patient pain understanding. Metaphor in treatment phases may be underutilised. Clinicians should encourage patient metaphor use in chronic pain communication.

Murrihy, RC, Drysdale, SAO, Dedousis-Wallace, A, Rémond, L, McAloon, J, Ellis, DM, Halldorsdottir, T, Greene, RW & Ollendick, TH 2023, 'Community-Delivered Collaborative and Proactive Solutions and Parent Management Training for Oppositional Youth: A Randomized Trial', Behavior Therapy, vol. 54, no. 2, pp. 400-417.
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Nasser, A, Grimaldi, A, Vicenzino, B, Rio, E, Rich, A, Pizzari, T & Semciw, A 2023, 'Towards development of a core outcome set in proximal hamstring tendinopathy - A systematic review of measurement instruments and their clinimetric properties', Musculoskeletal Science and Practice, vol. 66, pp. 102774-102774.
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OBJECTIVE: To find measurement instruments for proximal hamstring tendinopathy, map them to outcome domains, and evaluate their measurement properties. METHODS: There were three phases. Phase one involved a search of MEDLINE, CINAHL, EMBASE, SPORTSDISCUS and PUBMED (February 2022) to identify measurement instruments used in proximal hamstring tendinopathy research. In phase two we mapped these measurement instruments to the International Tendinopathy Scientific Consensus (ICON) core outcome domains. The third phase involved conducting a second search (same databases/census date) to identify studies that evaluated measurement properties of measurement instruments in participants with proximal hamstring tendinopathy. Measurement properties were then evaluated following the Consensus-based-Standards for the Selection of Health Instruments methodology -including risk of bias assessment and synthesis of findings. RESULTS: Twenty-eight different measurement instruments were identified in phase one. These were mapped to six of nine ICON domains in phase two. In phase three, there was only one instrument that had been evaluated for its measurement properties (4 studies, n = 302) - the Victorian Institute of Sport Assessment - Proximal Hamstring Tendinopathy (VISA-H). For the VISA-H there was moderate-quality evidence of sufficient construct validity, low-quality evidence of sufficient responsiveness, reliability and measurement error, very low-quality evidence of sufficient relevance and comprehensibility and very low-quality evidence of insufficient comprehensiveness. CONCLUSION: The VISA-H - mapped to the ICON disability domain - is the only one of the 28 different measurement instruments identified that was validated in this population. Caution in applying it is warranted given it is supported by lower quality evidence.

Newson, AJ, Deans, Z, Dive, L & Holmes, IC 2023, 'Consistency of What? Appropriately Contextualizing Ethical Analysis of Non-Invasive Prenatal Testing', The American Journal of Bioethics, vol. 23, no. 3, pp. 56-58.
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Norman, A, Lowe, R, Onslow, M, O'Brian, S, Packman, A, Menzies, R & Schroeder, L 2023, 'Cost of Illness and Health-Related Quality of Life for Stuttering: Two Systematic Reviews', Journal of Speech, Language, and Hearing Research, vol. 66, no. 11, pp. 4414-4431.
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Purpose: For those who stutter, verbal communication is typically compromised in social situations. This may attract negative responses from listeners and stigmatization by society. These have the potential to impair health-related quality of life across a range of domains, including qualitative and quantitative impacts on speech output, mental health issues, and failure to attain educational and occupational potential. These systematic reviews were designed to explore this matter using traditional health economics perspectives of utility measures and cost of illness. Method: Studies were included if they involved children, adolescents, or adults with stuttering as a primary diagnosis. The quality of life search strategy identified 2,607 reports, of which three were included in the quality of life analysis. The cost of illness search strategy identified 3,778 reports, of which 39 were included in the cost of illness analysis. Results: Two of the three studies included in the quality of life analysis had a high risk of bias. When measured using utility scores, quality of life for people who stutter was in the range of those reported for chronic health conditions such as diabetes mellitus, cardiovascular disease, and cancer. However, there is little such evidence of quality of life impairment during the preschool years. Studies included in the cost of illness analysis carried considerable risk of bias overall. Conclusions: For people who stutter, there are substantive direct and indirect costs of illness. These include impairment, challenges, and distress across many ...

Norton, AR, Penney, E & Abbott, MJ 2023, 'An exploratory investigation of schema modes in social anxiety disorder: Empirical findings and case conceptualization', Journal of Clinical Psychology, vol. 79, no. 4, pp. 1021-1038.
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AbstractBackgroundCurrent “gold standard” treatments for social anxiety disorder (SAD) are limited by the limited emphasis of key etiological factors in conceptualization, and many individuals with SAD experience residual symptoms posttreatment. Hence, the novel application of the Schema Therapy Mode Model may provide a helpful framework for extending clinical understanding and treatment options for SAD. This exploratory study aimed to investigate the presence and pattern of schema modes among SAD individuals.MethodForty individuals with SAD completed questionnaire measures of symptomatology, social anxiety‐relevant cognitions, schema modes, childhood trauma, and parental style.ResultsKey maladaptive schema modes identified in SAD were Vulnerable Child, Punitive Critic, Demanding Critic, Compliant Surrender, and Detached Self‐Soother.ConclusionOutcomes provide the basis for a proposed schema mode case conceptualization for SAD and are hoped to provide a rationale for testing the applicability of Schema Therapy as a novel treatment for SAD. Key limitations are discussed.

O’Shea, R, Crook, A, Jacobs, C, Kentwell, M, Gleeson, M, Tucker, KM, Hampel, H, Rahm, AK, Taylor, N, Lewis, S & Rankin, NM 2023, 'A mainstreaming oncogenomics model: improving the identification of Lynch syndrome', Frontiers in Oncology, vol. 13, p. 1140135.
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Introduction“Mainstreaming” is a proposed strategy to integrate genomic testing into oncology. The aim of this paper is to develop a mainstreaming oncogenomics model by identifying health system interventions and implementation strategies for mainstreaming Lynch syndrome genomic testing.MethodsA rigorous theoretical approach inclusive of conducting a systematic review and qualitative and quantitative studies was undertaken using the Consolidated Framework for Implementation Research. Theory-informed implementation data were mapped to the Genomic Medicine Integrative Research framework to generate potential strategies.ResultsThe systematic review identified a lack of theory-guided health system interventions and evaluation for Lynch syndrome and other mainstreaming programs. The qualitative study phase included 22 participants from 12 health organizations. The quantitative Lynch syndrome survey included 198 responses: 26% and 66% from genetic and oncology health professionals, respectively. Studies identified the relative advantage and clinical utility of mainstreaming to improve genetic test access and to streamline care, and adaptation of current processes was recognized for results delivery and follow-up. Barriers identified included funding, infrastructure and resources, and the need for process and role delineation. The interventions to overcome barriers were as follows: embedded mainstream genetic counselors, electronic medical record genetic test ordering, results tracking, and mainstreaming education resources. Implementation evidence was connected through the Genomic Medicine Integrative Research framework resulting in a mainstreaming oncogenomics model.DiscussionThe proposed mainstreaming oncogenomics model acts as a...

O'Brian, S, Hayhow, R, Jones, M, Packman, A, Iverach, L, Onslow, M & Menzies, R 2023, 'Lidcombe Program translation to community clinics in Australia and England', International Journal of Language & Communication Disorders, vol. 58, no. 2, pp. 295-309.
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AbstractBackgroundEarly intervention is essential healthcare for stuttering, and the translation of research findings to community settings is a potential roadblock to it.AimsThis study was designed to replicate and extend the Lidcombe Program community translation findings of O'Brian et al. (2013) but with larger participant numbers, incorporating clinicians (speech pathologists/speech anlanguage therapists) and their clients from Australia and England.Methods & ProceduresParticipants were 51 clinicians working in public and private clinics across Australia (n = 36) and England (n = 15), and 121 of their young stuttering clients and their families. Outcome measures were percentage of syllables stuttered (%SS), parent severity ratings at 9 months post‐recruitment, number of clinic visits to complete Stage 1 of the Lidcombe Program, and therapist drift.Outcomes & ResultsCommunity clinicians in both countries achieved similar outcomes to those from randomized controlled trials. Therapist drift emerged as an issue with community translation. Speech and language therapists in England attained outcomes 1.0%SS above the speech pathologists in Australia, although their scores were within the range attained in randomized trials.Conclusions & ImplicationsCommunity clinicians from Australia and England can attain Lidcombe Program outcome benchmarks established in randomized trials. This finding is reassuring in light of the controlled conditions in clinical trials of the Lidcombe Program compared with its conduct in community practice. The long‐term impact of therapist drift in commun...

Oey, LT, McDonald, S, McGrath, L, Dear, BF & Wootton, BM 2023, 'Guided versus self-guided internet delivered cognitive behavioural therapy for diagnosed anxiety and related disorders: a preliminary meta-analysis', Cognitive Behaviour Therapy, vol. 52, no. 6, pp. 654-671.
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Guided and self-guided internet-delivered cognitive-behavioural therapy (ICBT) has been demonstrated to be efficacious in the treatment of anxiety and related disorders (ARDs). The aim of the current study was to examine the efficacy of guided and self-guided ICBT for adults diagnosed with ARDs using a meta-analytic synthesis of randomised controlled trials directly comparing the two treatment approaches. Eleven studies (n = 1414) were included. There was a small, but significantly pooled between-group effect size at post-treatment (g = 0.16; 95% CI: 0.03-0.28) favouring guided ICBT. At follow-up, the between-group effect size was small and non-significant (g = 0.13; 95% CI: -0.04-0.30). Gender distribution moderated outcome at post-treatment (higher proportions of females resulted in a smaller between-group effect size). Type of support provided in the guided-treatment arm moderated treatment outcome at follow-up (those receiving synchronous support had a larger between-group effect size). Amount of guidance in the guided-treatment arm moderated effect sizes at post-treatment and follow-up (more guidance leading to larger between-group effect sizes). Automated reminders, disorder type, and treatment length did not moderate outcomes. The results suggest that guided and self-guided ICBT interventions result in similar outcomes, however guided interventions may be marginally more effective in the short term.

Okan, C, Bilson, L, Zhong, D, Weidemann, G & Bailey, PE 2023, 'Validating the interpersonal theory of suicide among older adultspre- and peri-COVID-19 pandemic', Aging & Mental Health, vol. 27, no. 8, pp. 1552-1558.
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OBJECTIVES: Global suicide rates are highest among older adults, and especially older men, yet proximal predictors of suicidal ideation in older age remain poorly understood. This study tested the Interpersonal Theory of Suicide in older men and women by investigating whether perceived burdensomeness and thwarted belongingness and/or their interaction are proximal predictors of suicidal ideation before versus during the global COVID-19 pandemic. METHODS: The sample (N = 208) included healthy community-dwelling older Australian persons surveyed face-to-face pre-pandemic (n = 102), or online peri-pandemic (n = 106). Depression, social interaction, social satisfaction, thwarted belongingness, and perceived burdensomeness were assessed as predictors of suicidal ideation. RESULTS: Perceived burdensomeness was a more proximal predictor of suicidal ideation among older adults than depression or thwarted belongingness. Suicidal ideation and perceived burdensomeness were higher in men than women, but sex did not moderate the influence of perceived burdensomeness, thwarted belongingness or social satisfaction on suicidal desire. The interaction between perceived burdensomeness and thwarted belongingness predicted more additional variance in suicidal ideation in the older persons surveyed during the COVID-19 pandemic relative to those surveyed before the pandemic. CONCLUSION: Suicidal ideation among older persons peri-pandemic is discussed, and recommendations are made for age-specific suicide prevention strategies.

Onslow, M, Lowe, R, Jakšić, SJ, Franken, M-C, Hearne, A, Uijterlinde, I & Eggers, K 2023, 'The Fifth Croatia Stuttering Symposium: Part III. Mental health and early stuttering', Journal of Fluency Disorders, vol. 77, pp. 106000-106000.
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PURPOSE: The Fifth Croatia Stuttering Symposium of 2022 continued the Fourth Croatia Stuttering Symposium 2019 theme of the connection between research and clinical practice. At the 2022 Symposium, there were 145 delegates from 21 countries. This paper documents the contents of the third of three Symposium modules. METHODS: The module topic was mental health and early stuttering, and that pre-schoolers who stutter are at risk of developing mental health issues. A clinical situation was considered where a parent of a 3-year-old child asked a clinician what the early signs of mental health issues might be for a child who stutters. RESULTS: A distinguished scholar presented a 5-minute video interpretation of research about this topic. Three master clinicians then each presented a 2-minute video demonstration of how that research might be applied in a clinical situation. Following that, the convenors moderated a discussion between the distinguished scholar, master clinicians, and delegates regarding the research and how it applies to clinical practice.

Onslow, M, Lowe, R, Jelčić Jakšić, S, Packman, A, Kelly, E, MacMillan, V & Hodes, G 2023, 'The Fifth Croatia Stuttering Symposium: Part II. Natural recovery from early stuttering', Journal of Fluency Disorders, vol. 78, pp. 106018-106018.
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PURPOSE: The Fifth Croatia Stuttering Symposium of 2022 continued the Fourth Croatia Stuttering Symposium 2019 theme of the connection between research and clinical practice. At the 2022 Symposium, there were 145 delegates from 21 countries. This paper documents the contents of the second of three Symposium modules. METHODS: The module topic was that some children with early stuttering will recover naturally. A clinical situation was considered where a parent of a 3-year-old child asked if a clinician can predict whether their child will recover from stuttering without treatment. RESULTS: A distinguished scholar presented a 5-minute video interpretation of research about this topic. Three master clinicians then each presented a 2-minute video demonstration of how that research might be applied in a clinical situation. Following that, the convenors moderated a discussion between the distinguished scholar, master clinicians, and delegates regarding the research and how it applies to clinical practice.

Pace, T, Koenig-Robert, R & Pearson, J 2023, 'Different Mechanisms for Supporting Mental Imagery and Perceptual Representations: Modulation Versus Excitation', Psychological Science, vol. 34, no. 11, pp. 1229-1243.
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Recent research suggests imagery is functionally equivalent to a weak form of visual perception. Here we report evidence across five independent experiments on adults that perception and imagery are supported by fundamentally different mechanisms: Whereas perceptual representations are largely formed via increases in excitatory activity, imagery representations are largely supported by modulating nonimagined content. We developed two behavioral techniques that allowed us to first put the visual system into a state of adaptation and then probe the additivity of perception and imagery. If imagery drives similar excitatory visual activity to perception, pairing imagery with perceptual adapters should increase the state of adaptation. Whereas pairing weak perception with adapters increased measures of adaptation, pairing imagery reversed their effects. Further experiments demonstrated that these nonadditive effects were due to imagery weakening representations of nonimagined content. Together these data provide empirical evidence that the brain uses categorically different mechanisms to represent imagery and perception.

Pandian, V, Atkins, JH, Freeman-Sanderson, A, Prush, N, Feller-Kopman, DJ, McGrath, BA & Brenner, MJ 2023, 'Improving airway management and tracheostomy care through interprofessional collaboration: aligning timing, technique, and teamwork', Journal of Thoracic Disease, vol. 15, no. 5, pp. 2363-2370.
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Panditaratne, S, Hronis, A, Roberts, R & Kneebone, I 2023, 'Participant experiences of Fearless Me! ©: Cognitive behaviour therapy for anxiety in children with intellectual disabilities', Current Psychology, vol. 42, no. 25, pp. 21278-21286.
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AbstractResearch shows that almost half of children with intellectual disabilities (ID) experience mental ill-health at any given time point. However, traditional cognitive behaviour therapy (CBT) may not be appropriate for children with ID due to the cognitive deficits associated with their diagnosis. The Fearless Me! © CBT program for anxiety is adapted to accommodate the cognitive abilities of children with ID. The aim of the current study was to provide the first qualitative evaluation of the Fearless Me! © program by exploring participant experiences. Eight mother–child dyads were interviewed using a semi-structured protocol. The responses were transcribed and analysed using thematic analysis. Identified codes and themes were cross-checked with an independent researcher and discrepancies were resolved. Parents found the program to be positive and useful for acquiring knowledge. They commented on features of the program, significance of inter- and intra-personal factors and whether the program suited the capability of their child. They also discussed features of treatment outcomes. The qualitative results highlighted that experiences of the program varied. Themes identified included those relating to barriers and facilitators to participation and treatment-related change. The themes provide guidance for program revisions and can inform future delivery of the Fearless Me! © program.

Pate, JW, Ilhan, E, Rush, GQ, Kennedy, DS, Verhagen, A, Pacey, V & Stubbs, PW 2023, 'Assessing the Reconceptualization of Pain in Graduate-Entry Physiotherapy Students Using the Concept of Pain Inventory for Adults: The University of Technology Sydney Physiotherapy Student Surveys Project', Journal of Physical Therapy Education, vol. 37, no. 4, pp. 302-307.
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Introduction. Validly and reliably assessing conceptual change is essential for evaluating the effectiveness of pain science education for physiotherapy students. We aimed to 1) evaluate concept of pain before and after a 14-week pain science education university subject, 2) assess structural validity of the Concept of Pain Inventory for Adults (COPI-Adult) in postgraduate entry-level physiotherapy students, and 3) explore possible relationships between baseline variables and baseline COPI-Adult scores. Review of Literature. As the COPI-Adult is a newly developed questionnaire, there is a lack of data regarding its psychometric properties. Subjects. Of 129 enrolled students at an Australian university, 124 (96%) and 114 (88%) completed the baseline and follow-up questionnaires, respectively. Methods. In this prospective cohort study, students who commenced the degree in 2020 or 2021 completed online questionnaires, including the COPI-Adult, at the start and end of their first semester. This semester included a 14-week pain science education subject and other physiotherapy-related subjects. Higher COPI-Adult scores (range = 0–52) indicate better alignment with contemporary pain science. We 1) compared differences in concept of pain before and after the semester, 2) performed a confirmatory factor analysis on the COPI-Adult, and 3) performed exploratory regression analyses. Results. Concept of Pain Inventory for Adults scores increased from baseline (median [in...

Patel, VK, Vishwas, S, Kumar, R, De Rubis, G, Shukla, SD, Paudel, KR, Manandhar, B, Singh, TG, Chellappan, DK, Gulati, M, Kaur, IP, Allam, VSRR, Hansbro, PM, Oliver, BG, MacLoughlin, R, Singh, SK & Dua, K 2023, 'Tackling the cytokine storm using advanced drug delivery in allergic airway disease', Journal of Drug Delivery Science and Technology, vol. 82, pp. 104366-104366.
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Paudel, KR, Rajput, R, De Rubis, G, Raju Allam, VSR, Williams, KA, Singh, SK, Gupta, G, Salunke, P, Hansbro, PM, Gerlach, J & Dua, K 2023, 'In vitro anti-cancer activity of a polyherbal preparation, VEDICINALS®9, against A549 human lung adenocarcinoma cells', Pathology - Research and Practice, vol. 250, pp. 154832-154832.
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Paykel, M, Ridley, E, Freeman-Sanderson, A, Ramanan, M, Booth, S, Cook, K, Ip, K, De Gori, M, Blackshaw, J, Markham, D, Downie, S & Haines, K 2023, 'Allied health surge capacity in Australian intensive care units during the COVID-19 pandemic: A cross-sectional survey', Australian Critical Care, vol. 36, no. 1, pp. 108-113.
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Peters, R, Schmitt, M, Mutsaers, B, Buyl, R, Verhagen, A, Pool-Goudzwaard, A & Koes, B 2023, 'Identifying Patient Characteristics Associated With the Occurrence of Post Treatment Non-serious Adverse Events After Cervical Spine Manual Therapy Treatment in Patients With Neck Pain', Archives of Physical Medicine and Rehabilitation, vol. 104, no. 2, pp. 277-286.
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Pommerich, UM, Stubbs, PW, Eggertsen, PP, Fabricius, J & Nielsen, JF 2023, 'Regression-based prognostic models for functional independence after postacute brain injury rehabilitation are not transportable: a systematic review', Journal of Clinical Epidemiology, vol. 156, pp. 53-65.
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Pride, NA, Haebich, KM, Walsh, KS, Lami, F, Rouel, M, Maier, A, Chisholm, AK, Lorenzo, J, Hearps, SJC, North, KN & Payne, JM 2023, 'Sensory Processing in Children and Adolescents with Neurofibromatosis Type 1', Cancers, vol. 15, no. 14, pp. 3612-3612.
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Despite the evidence of elevated autistic behaviors and co-occurring neurodevelopmental difficulties in many children with neurofibromatosis type 1 (NF1), we have a limited understanding of the sensory processing challenges that may occur with the condition. This study examined the sensory profile of children and adolescents with NF1 and investigated the relationships between the sensory profiles and patient characteristics and neuropsychological functioning. The parent/caregivers of 152 children with NF1 and 96 typically developing children completed the Sensory Profile 2 (SP2), along with standardized questionnaires assessing autistic behaviors, ADHD symptoms, internalizing symptoms, adaptive functioning, and social skills. Intellectual functioning was also assessed. The SP2 data indicated elevated sensory processing problems in children with NF1 compared to typically developing children. Over 40% of children with NF1 displayed differences in sensory registration (missing sensory input) and were unusually sensitive to and unusually avoidant of sensory stimuli. Sixty percent of children with NF1 displayed difficulties in one or more sensory modalities. Elevated autistic behaviors and ADHD symptoms were associated with more severe sensory processing difficulties. This first detailed assessment of sensory processing, alongside other clinical features, in a relatively large cohort of children and adolescents with NF1 demonstrates the relationships between sensory processing differences and adaptive skills and behavior, as well as psychological well-being. Our characterization of the sensory profile within a genetic syndrome may help facilitate more targeted interventions to support overall functioning.

Richardson, E, McEwen, A, Newton‐John, T & Jacobs, C 2023, 'Defining core outcomes of reproductive genetic carrier screening: A Delphi survey of Australian and New Zealand stakeholders', Prenatal Diagnosis, vol. 43, no. 9, pp. 1150-1165.
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AbstractObjectiveUnderstanding the value, benefits and harms of health interventions is needed to inform best practice and ensure responsible implementation of new approaches to patient care. Such value is demonstrated through the assessment of outcomes; however, which outcomes are assessed is often highly varied across studies and can hinder the ability to draw robust conclusions. The Core Outcome Development for Carrier Screening study aims to understand the outcomes that can meaningfully capture the value of reproductive genetic carrier screening (RGCS).MethodThe authors report an iterative, two‐round online Delphi survey of Australian and New Zealand stakeholders to determine the degree of consensus regarding the core outcomes of RGCS. Panellists ranked 83 outcomes according to their perceived importance on a nine‐point Likert scale. Using the distribution of rankings, outcomes were grouped into tiers representative of their perceived level of importance and agreement between groups.ResultsThe top tier outcomes represent those agreed to be critically important for all future studies of RGCS to assess and were used to define a preliminary core outcome set encompassing the domains (1) primary laboratory outcomes, (2) pregnancy outcomes, (3) resource use and, (4) perceived utility of RGCS.ConclusionThese findings can guide the selection of meaningful outcomes in studies aiming to demonstrate the value of RGCS. A future international consensus process will expand on these findings and guide the inclusion of diverse perspectives across the range of settings in which RGCS is offered.

Ross, A, Grove, R & McAloon, J 2023, 'The relationship between camouflaging and mental health in autistic children and adolescents', Autism Research, vol. 16, no. 1, pp. 190-199.
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AbstractCamouflaging involves the masking of autistic traits in social situations. While camouflaging may function as a potential barrier to the early diagnosis of autism, minimal research into camouflaging in autistic young people has been conducted. It is also important to evaluate the impact of camouflaging on the mental health of autistic children and adolescents. This study evaluated camouflaging in a sample of 359 female and 374 male autistic children and adolescents (4–17 years, 48.9% females). Findings indicated that camouflaging was a significant predictor of internalizing (i.e., anxiety, depression, somatic complaints) symptoms, when controlling for age, gender, and IQ. We also found evidence for some gender differences in camouflaging. Parents endorsed more autistic traits for females compared with males, whereas there were no differences in autistic traits across sex in the clinician‐administered assessment. There was also evidence for a relationship between age and camouflaging, with adolescents showing a larger discrepancy between parent and clinician reported autistic traits. This has implications for clinical assessment and future research and is important for understanding how best to support the mental health of autistic children and adolescents.

Ryan, B, Kneebone, I, Rose, ML, Togher, L, Power, E, Hoffmann, T, Khan, A, Simmons-Mackie, N, Carragher, M & Worrall, L 2023, 'Preventing depression in aphasia: A cluster randomized control trial of the Aphasia Action Success Knowledge (ASK) program', International Journal of Stroke, vol. 18, no. 8, pp. 996-1004.
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Background: Stroke patients with aphasia and their caregivers have higher incidence of depression than those without aphasia. Aims: The objective of the study is to determine whether a tailored intervention program (Action Success Knowledge; ASK) led to better mood and quality of life (QoL) outcomes than an attention control with a 12-month end point at cluster and individual participant level. Methods: A multi-site, pragmatic, two-level single-blind cluster randomized controlled trial compared ASK to an attention control (secondary stroke prevention program). Ten metropolitan and 10 non-metropolitan health regions were randomized. People with aphasia and their family members were recruited within 6 months post-stroke who scored ⩽12 on the Stroke Aphasic Depression Questionnaire Hospital Version–10 at screening. Each arm received manualized intervention over 6–8 weeks followed by monthly telephone calls. Blinded assessments of QoL and depression were taken at 12 months post-onset. Results: Twenty clusters (health regions) were randomized. Trained speech pathologists screened 1744 people with aphasia and 373 participants consented to intervention (n = 231 people with aphasia and 142 family members). The attrition rate after consent was 26% with 86 and 85 participants with aphasia in the ASK arm and attention control arm, respectively, receiving intervention. Of those 171 who did receive treatment, only 41 met the prescribed minimum dose. Multilevel mixed effects modeling under the intention-to-treat protocol showed a significant difference on the Stroke and Aphasia Depression Questionnaire–21 (SADQ-21, N = 122, 17 clusters) in favor of the attention control (β = –2.74, 95% confidence interval (CI) = –4.76 to –0.73, p = 0.008)....

Saylor, KW, Klein, WMP, Calancie, L, Lewis, KL, Biesecker, LG, Turbitt, E & Roberts, MC 2023, 'Genetic Testing and Other Healthcare Use by Black and White Individuals in a Genomic Sequencing Study', Public Health Genomics, vol. 26, no. 1, pp. 90-102.
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<b><i>Introduction:</i></b> Early adopters play a critical role in the diffusion of medical innovations by spreading awareness, increasing acceptability, and driving demand. Understanding the role of race in the context of other characteristics of potential early adopters can shed light on disparities seen in the early implementation of genomic medicine. We aimed to understand the association between self-identified race and individual experience with genetic testing outside of the research context. <b><i>Methods:</i></b> We assessed factors associated with the odds of having ever received genetic testing prior to enrollment in a genomic sequencing study among 674 self-identified white and 407 self-identified African, African American, or Afro-Caribbean (“Black”) individuals. <b><i>Results:</i></b> Controlling for individual determinants of healthcare use (demographics, personality traits, knowledge and attitudes, and health status), identifying as Black was associated with lower odds of prior genetic testing (OR = 0.43, 95% CI [0.27–0.68], <i>p</i> &lt; 0.001). In contrast, self-identified race was not associated with the use of non-genetic clinical screening tests (e.g., echocardiogram, colonoscopy). Black and white individuals were similar on self-reported personality traits tied to early adoption but differed by sociodemographic and resource facilitators of early adoption. <b><i>Conclusion:</i></b> Persistent racial disparities among early adopters may represent especially-entrenched disparities in access to and knowledge of genomic technologies in clinical settings.

Schulz, M, Griese-Mammen, N & Müller, U 2023, 'Clinical pharmacy services are reimbursed in Germany: challenges of real world implementation remain', International Journal of Clinical Pharmacy, vol. 45, no. 1, pp. 245-249.
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AbstractOver the last two decades, community pharmacy has experienced major changes as the role of pharmacists is evolving from a product to a service and a patient focus. As part of this change, new and innovative clinical pharmacy services aimed at improving medicines use and patient outcomes have been designed, both nationally and internationally. Since June 2022, five services are reimbursed by all statutory health insurance funds and private insurance companies in Germany: medication review for patients with polymedication; blood pressure control in hypertension; assuring proper inhalation techniques for patients receiving a new device or a device change; medication review including a follow-up for patients taking oral anticancer drugs or immunosuppressants post-transplantation. Beyond reimbursement, the upscaling and sustainable provision of these professional services are now the main challenges. Implementation research will provide important information for the further development of pharmaceutical care programs.

Scott, AJ, Bisby, MA, Heriseanu, AI, Salameh, Y, Karin, E, Fogliati, R, Dudeney, J, Gandy, M, McLellan, LF, Wootton, B, McDonald, S, Correa, A, Titov, N & Dear, BF 2023, 'Cognitive behavioral therapies for depression and anxiety in people with chronic disease: A systematic review and meta-analysis', Clinical Psychology Review, vol. 106, pp. 102353-102353.
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OBJECTIVE: Anxiety and depression in chronic disease are common and burdensome co-morbidities. There has been growing interest in cognitive and behavioral therapies (CBTs) for anxiety and depression in chronic disease, however their efficacy has not been well-established. This study examined the efficacy of CBTs for depression and/or anxiety symptoms within chronic disease and explored the moderating role of clinical and methodological characteristics. METHODS: Following prospective registration, electronic databases were searched up to 2023 for randomized controlled trials (RCTs) examining CBTs for depression and/or anxiety in any adult chronic disease population. RESULTS: We included 56 RCTs. The overall effect of CBTs was g = 0.61 (95% CI, 0.49, 0.72) for depression and g = 0.56 (95% CI, 0.42, 0.70) for anxiety. A range of methodological features significantly moderated the effect sizes obtained, including type of control group and the outcome measure used. Risk of Bias ratings indicated some concerns regarding RCT conduct and reporting. CONCLUSIONS: CBTs lead to moderate improvements in both depression and anxiety symptoms among people with chronic disease. However, the efficacy of CBT should be interpreted considering certain study and sample characteristics. It is recommended that future studies make improvements to study methodology and reporting.

Seah, R & Berle, D 2023, 'Does Exposure to Interpersonal Trauma Influence the Relationship between Shame and Posttraumatic Stress Symptoms?', Journal of Aggression, Maltreatment & Trauma, vol. 32, no. 9, pp. 1304-1320.
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Although shame is a common emotional response to trauma exposure, it may be precipitated by distinct trauma types. To our knowledge, our study is the first to investigate the relationship between shame and PTSD symptom severity and whether exposure to at least one interpersonal trauma influences the relationship between shame and PTSD symptoms. One-hundred and fifty-seven participants from Australia, Canada, United States, United Kingdom, and New Zealand completed a series of self-report measures. Although shame was significantly associated with PTSD symptom severity, it was not an independent predictor of PTSD when considering anxiety, depression, trauma history and guilt. Participants exposed to at least one interpersonal traumatic event endorsed higher levels of shame and PTSD compared to those who did not. Interpersonal trauma exposure also moderated the relationship between shame and PTSD. Clinical implications and directions for future research are also discussed.

Seah, R, Dwyer, K & Berle, D 2023, 'Was it me? The Role of Attributions and Shame in Posttraumatic Stress Disorder (PTSD): A Systematic Review', Trends in Psychology, pp. 1-22.
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AbstractShame has been identified as a key emotional response to trauma exposure and is implicated in the development and maintenance of PTSD. Despite this, there is a lack of empirical research explaining how and why shame emerges following trauma exposure. Current theoretical models of shame converge on the idea that shame is elicited through internal, stable, and global attributions about the precipitating event. A systematic review was conducted to assess the relationship between causal attributions, shame, and PTSD symptomology. A database search of PsycINFO, PubMED, Medline, EMBASE and PTSDPubs identified articles published between 1980 to 2022 that enabled examination of the relationship between attributions, shame, and PTSD. A total of eight articles met inclusion criteria for this review. There were cross-sectional relationships between internal attributions, shame, and PTSD symptoms, with shame demonstrating the strongest relationship with PTSD symptoms. Significant indirect effects were found between internal attributions, shame, and PTSD. Concerns surrounding reliability of measurements and sampling bias made it difficult to draw definitive conclusions. The current evidence is too preliminary to offer strong support for the mediation hypothesis. However, it does offer important avenues for future research that will have important clinical applications.

Sekhon, JK, Oates, J, Kneebone, I & Rose, ML 2023, 'A phase II randomised controlled trial evaluating the feasibility and preliminary efficacy of an education program on speech-language pathologist’ self-efficacy, and self-rated competency for counselling to support psychological wellbeing in people with post-stroke aphasia', Topics in Stroke Rehabilitation, vol. 30, no. 8, pp. 842-864.
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Sharma, DS, Wadhwa, S, Gulati, M, Kumar, B, Chitranshi, N, Gupta, VK, Alrouji, M, Alhajlah, S, AlOmeir, O, Vishwas, S, Khursheed, R, Saini, S, Kumar, A, Parveen, SR, Gupta, G, Zacconi, F, Chellappan, DK, Morris, A, Loebenberg, R, Dua, K & Singh, SK 2023, 'Chitosan modified 5-fluorouracil nanostructured lipid carriers for treatment of diabetic retinopathy in rats: A new dimension to an anticancer drug', International Journal of Biological Macromolecules, vol. 224, pp. 810-830.
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Sharma, S, Verhagen, A, Elkins, M, Brismée, J-M, Fulk, GD, Taradaj, J, Steen, L, Jette, A, Moore, A, Stewart, A, Hoogenboom, BJ, Söderlund, A, Harms, M & Pinto, RZ 2023, 'Research From Low-Income and Middle-Income Countries Will Benefit Global Health and the Physiotherapy Profession, but It Requires Support', Physical Therapy, vol. 103, no. 9, pp. 238-242.
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Sharma, S, Verhagen, A, Elkins, M, Brismée, J-M, Fulk, GD, Taradaj, J, Steen, L, Jette, A, Moore, A, Stewart, A, Hoogenboom, BJ, Söderlund, A, Harms, M & Pinto, RZ 2023, 'Research from low-income and middle-income countries will benefit global health and the physiotherapy profession, but it requires support', Musculoskeletal Science and Practice, vol. 67, pp. 102836-102836.
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Sharma, S, Verhagen, A, Elkins, M, Brismée, J-M, Fulk, GD, Taradaj, J, Steen, L, Jette, A, Moore, A, Stewart, A, Hoogenboom, BJ, Söderlund, A, Harms, M & Pinto, RZ 2023, 'Research from low-income and middle-income countries will benefit global health and the physiotherapy profession, but it requires support', European Journal of Physiotherapy, vol. 25, no. 5, pp. 238-242.
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Sharma, S, Verhagen, A, Elkins, M, Brismée, J-M, Fulk, GD, Taradaj, J, Steen, L, Jette, A, Moore, A, Stewart, A, Hoogenboom, BJ, Söderlund, A, Harms, M & Pinto, RZ 2023, 'Research from low-income and middle-income countries will benefit global health and the physiotherapy profession, but it requires support', Physiotherapy, vol. 121, pp. A1-A5.
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Sharma, S, Verhagen, A, Elkins, M, Brismée, J-M, Fulk, GD, Taradaj, J, Steen, L, Jette, A, Moore, A, Stewart, A, Hoogenboom, BJ, Söderlund, A, Harms, M & Pinto, RZ 2023, 'Research from low-income and middle-income countries will benefit global health and the physiotherapy profession, but it requires support', Brazilian Journal of Physical Therapy, vol. 27, no. 5, pp. 100530-100530.
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Sharma, S, Verhagen, AP, Elkins, M, Brismée, J-M, Fulk, GD, Taradaj, J, Steen, L, Jette, A, Moore, A, Stewart, A, Hoogenboom, BJ, Söderlund, A, Harms, M & Pinto, RZ 2023, 'Research from low-income and middle-income countries will benefit global health and the physiotherapy profession, but it requires support', Journal of Manual & Manipulative Therapy, vol. 31, no. 5, pp. 305-310.
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Shenker, R, Rodgers, N, Guitar, B & Onslow, M 2023, 'Contemporary clinical conversations about stuttering: Neurodiversity and ableism', Journal of Fluency Disorders, vol. 78, pp. 106014-106014.
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Purpose: To discuss issues about neurodiversity and ableism, and how they pertain to clinical management of stuttering, with particular reference to early childhood stuttering. Methods: During a webinar this year, the issue emerged of how concepts of neurodiversity and ableism apply to early childhood stuttering during the pre-school years. It became apparent that this topic elicited disparate views and would be of particular interest to students of speech-language pathology. Consequently, the leaders of that webinar continued the conversation by written dialogue for the purpose of placing it on record. Results: The discussants reached agreement on many points, but there was some diversity of viewpoint about how neurodiversity and ableism should apply to clinical practice with children who have recently begun to stutter.

Shires, A, Osborne, S, Cayoun, BA, Williams, E & Rogers, K 2023, 'Predictive Validity and Response Shift in the Equanimity Scale-16', Mindfulness, vol. 14, no. 12, pp. 2880-2893.
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Silva, NS, Elkins, MR, Lemes, ÍR, Stubbs, PW, Franco, MR & Pinto, RZ 2023, 'Clinical trial registration has become more prevalent in physical therapy but it is still inadequate: A meta-research study', Musculoskeletal Science and Practice, vol. 67, pp. 102854-102854.
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Simos, A & Berle, D 2023, 'The phenomenology of nightmares in post-traumatic stress disorder and complex post-traumatic stress disorder', European Journal of Trauma & Dissociation, vol. 7, no. 3, pp. 100335-100335.
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Smit, CCH, Rogers, K, Robertson, H, Taxis, K & Pont, LG 2023, 'Real-World Data about Commonly Used Antibiotics in Long-Term Care Homes in Australia from 2016 to 2019', Antibiotics, vol. 12, no. 9, pp. 1393-1393.
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In this study, we use real-world data to explore trends in antibiotic use in a dynamic cohort of long-term care (LTC) residents. A cross-sectional retrospective analysis of pharmacy medication supply records of 3459 LTC residents was conducted from 31 May 2016 to 31 May 2019. The primary outcome was the monthly prevalence of residents with an antibiotic episode. Secondary outcomes were the type of antibiotic used and duration of use. Over the three-year study period, residents were supplied 10460 antibiotics. On average, 18.9% of residents received an antibiotic monthly. Antibiotic use decreased slightly over time with a mean of 168/1000 (95% CI 146–177) residents using at least one antibiotic per month in June 2016 to 148/1000 (95% CI 127–156) in May 2019. The total number of antibiotic days per 100 resident days remained relatively constant over the study period: 8.8 days in 2016–2017, 8.4 in 2017–2018 and 6.4 in 2018–2019. Prolonged durations exceeding 100 days were seen for a small percentage of residents. We found extensive antibiotic use, which is a recognized contributor to antimicrobial resistance development, underscoring the necessity for quality treatment guidelines in this vulnerable population.

Smith, R, Bryant, L & Hemsley, B 2023, 'The true cost of dysphagia on quality of life: The views of adults with swallowing disability', International Journal of Language & Communication Disorders, vol. 58, no. 2, pp. 451-466.
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AbstractBackgroundDysphagia impacts negatively on quality of life, however there is little in‐depth qualitative research on these impacts from the perspective of people with dysphagia.AimsTo examine the lived experiences and views of people with lifelong or ongoing dysphagia on the impacts of dysphagia and its interventions on quality of life, and barriers and facilitators to improved quality of life related to mealtimes.Methods & ProceduresNine adults with lifelong or acquired chronic dysphagia engaged in in‐depth interviews and a mealtime observation. The observations were recorded and scored using the Dysphagia Disorders Survey (DDS). Interviews were recorded, transcribed and de‐identified before content thematic and narrative analysis, and verification of researcher interpretations.Outcomes & ResultsParticipants presented with mild to severe dysphagia as assessed by the DDS. They viewed that dysphagia and its interventions reduced their quality of life and that they had ‘paid a high price’ in terms of having reduced physical safety, reduced choice and control, poor mealtime experiences, and poor social engagement. As part of their management of dysphagia, participants identified several barriers to and facilitators for improved quality of life including: being involved in the design of their meals, being adaptable, having ownership of swallowing difficulties, managing the perceptions of others and resisting changes to oral intake.Conclusions & ImplicationsThis research improves understanding of the primary concerns of people with dysphagia about their mealtime experiences and factors impacting on their quality of life. Clin...

Starcevic, V, Eslick, GD, Viswasam, K, Billieux, J, Gainsbury, SM, King, DL & Berle, D 2023, 'Problematic online behaviors and psychopathology in Australia', Psychiatry Research, vol. 327, pp. 115405-115405.
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This study aimed to ascertain frequency rates and predictors of six problematic online behaviors (POBs) in an Australian sample. Participants (N = 1626) completed instruments measuring problematic online gaming, cyberchondria, problematic cybersex, problematic online shopping, problematic use of social networking sites, problematic online gambling, anxiety, depression and attention deficit/hyperactivity disorder (ADHD). Each POB was presumed to be present based on the cut-off score on the corresponding instrument and at least one indicator of interference with functioning. Generalized linear model analyses were used to determine socio-demographic and psychopathological predictors of each POB. The most common POB was problematic online shopping (12.2%), followed by problematic online gambling (11.4%), problematic use of social networking sites (6.0%), problematic cybersex (5.3%), problematic online gaming (5.2%) and cyberchondria (4.6%). Age group 27-36 had the highest rates of POBs. The intensity of ADHD symptoms predicted all POBs, whereas younger age predicted all POBs except for problematic cybersex and online gambling. Female gender predicted lower scores on the measures of problematic online gaming and cybersex. These findings have implications for age- and gender-adapted education, prevention and treatment efforts and suggest that specific POBs should be investigated separately instead of lumping them together under the umbrella terms such as 'Internet addiction'.

Stark, BC, Bryant, L, Themistocleous, C, den Ouden, D-B & Roberts, AC 2023, 'Best practice guidelines for reporting spoken discourse in aphasia and neurogenic communication disorders', Aphasiology, vol. 37, no. 5, pp. 761-784.
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Stavropoulos, A, Brockman, R, Hayes, C, Rogers, K & Berle, D 2023, 'A single case series of imagery rescripting of intrusive autobiographical memories in depression.', J Behav Ther Exp Psychiatry, vol. 81, pp. 101854-101854.
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BACKGROUND AND OBJECTIVES: Intrusive memories are a common feature of depression, thought to be related to the onset and maintenance of the disorder. Intrusive memories have been successfully targeted in posttraumatic stress disorder through imagery rescripting. Yet there is limited evidence for the effectiveness of this technique in depression. We examined whether 12 weekly sessions of imagery rescripting was associated with reductions in depression, rumination and intrusive memories in a sample of patients with major depressive disorder (MDD). METHODS: Fifteen clinically depressed participants completed 12 weeks of imagery rescripting treatment while completing daily measures of depression symptoms, rumination and intrusive memory frequency. RESULTS: There were significant reductions on pre-post treatment and daily assessment measures of depression symptoms, rumination and intrusive memories. Reductions in depression symptoms represented a large effect size, while 13 participants (87%) showed reliable improvement and 12 participants (80%) demonstrated clinically significant improvement and no longer met diagnostic criteria for MDD. LIMITATIONS: The sample size was small, however the intensive daily assessment protocol ensured the viability of within-person analyses. CONCLUSIONS: Imagery rescripting as a stand-alone intervention appears to be effective at reducing depression symptoms. Additionally, the treatment was well tolerated by clients and observed to overcome several traditional treatment barriers in this population.

Sullivan, R, Harding, K, Skinner, I & Hemsley, B 2023, 'Falls in Patients With Communication Disability Secondary to Stroke', Clinical Nursing Research, vol. 32, no. 3, pp. 478-489.
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Patients with stroke are at high risk of falls during inpatient rehabilitation admission. Communication disability is common following stroke; however, this population is often excluded from falls research. This study aimed to examine the falls of patients with communication disability following stroke, including the circumstances, contributing factors, and outcomes of the fall. This medical record review used the Generic Reference Model of patient safety as the analytical lens and data were analyzed descriptively. The study included 109 patients who experienced 308 falls. The most common type of fall was an “unwitnessed roll from bed.” Patient factors contributed to half of all falls, injuries occurred in 15% of falls, and impacts to the hospital system included additional costs and staffing. Understanding the reasons why patients are attempting to get out of bed may identify ways to reduce the risk and incidence of falls in this population.

Sullivan, R, Hemsley, B, Harding, K & Skinner, I 2023, '‘Patient unable to express why he was on the floor, he has aphasia.’ A content thematic analysis of medical records and incident reports on the falls of hospital patients with communication disability following stroke', International Journal of Language & Communication Disorders, vol. 58, no. 6, pp. 2033-2048.
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AbstractBackgroundPeople with communication disability following stroke are at risk of falls during inpatient rehabilitation. However, they are often excluded from hospital falls research, and little is known about the circumstances or outcomes of their falls to inform risk management strategies.AimsTo examine hospital medical records and incident reports relating to falls of patients with communication disability following stroke for content codes, categories and themes relating to communication.Methods & ProceduresThis medical record chart review examined data on 72 patients and 265 falls. A content thematic analysis was used to identify how patient communication is characterized in relation to falls, and their prevention and management strategies.Outcomes & ResultsThe data reflected that staff viewed patients having difficulty following simple instructions as contributing to falls. Gaining the attention of staff and communicating basic needs were also considered to be contributing factors for falls. Patients were often described as experiencing a fall when taking a risk or attempting to address an unmet basic need. Furthermore, written notes for patients with more severe communication disability reflected that the patient's communication impairments prevented staff from establishing the circumstances of some falls and complicated the assessment for injury following a fall.Conclusions & ImplicationsThe medical records and incident reports of patients with communication disability following stroke reveal that hospital staff recognize the impact of communication disability as potential risk factors for falls for this group. It ...

Sullivan, R, Hemsley, B, Skinner, I & Harding, K 2023, 'Hospital policies on falls in relation to patients with communication disability: a scoping review and content analysis', Australian Health Review, vol. 47, no. 4, pp. 487-493.
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Objective Falls in hospital are a significant public health issue and patients with communication disability have unique risk factors that have the potential to contribute to falls. The aim of this study is to determine how the content of hospital falls policies relate to patients with communication disability and to identify gaps in policy that need to be addressed. Methods A scoping review and content analysis of (a) policies and related documents, from a target health service in Victoria, Australia, and all relevant Australian state and territory health departments, and (b) national guidelines was performed. Data were analysed for content relating to inclusion of patients with communication disability. Results Communication disability is not captured as a risk factor for a fall in assessment tools. When included, aspects of communication disability were often conflated with cognitive impairments. There was little guidance for staff on adapting falls prevention education to suit the needs of patients with communication disability and limited identified role for speech pathologists. Conclusion This study suggests that a patient’s communication disability is not visible in hospital falls policies and guidelines.

Sutton, G & Hodge, C 2023, 'If you like it, should you really put a ring in it?', Clinical & Experimental Ophthalmology, vol. 51, no. 7, pp. 659-660.
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Taber, JM, Peters, E, Klein, WMP, Cameron, LD, Turbitt, E & Biesecker, BB 2023, 'Motivations to learn genomic information are not exceptional: Lessons from behavioral science', Clinical Genetics, vol. 104, no. 4, pp. 397-405.
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AbstractWhether to undergo genome sequencing in a clinical or research context is generally a voluntary choice. Individuals are often motivated to learn genomic information even when clinical utility—the possibility that the test could inform medical recommendations or health outcomes—is low or absent. Motivations to seek one's genomic information can be cognitive, affective, social, or mixed (e.g., cognitive and affective) in nature. These motivations are based on the perceived value of the information, specifically, its clinical utility and personal utility. We suggest that motivations to learn genomic information are no different from motivations to learn other types of personal information, including one's health status and disease risk. Here, we review behavioral science relevant to motivations that may drive engagement with genome sequencing, both in the presence of varying degrees of clinical utility and in the absence of clinical utility. Specifically, we elucidate 10 motivations that are expected to underlie decisions to undergo genome sequencing. Recognizing these motivations to learn genomic information will guide future research and ultimately help clinicians to facilitate informed decision making among individuals as genome sequencing becomes increasingly available.

Talbot, B, Cass, A, Walker, R, Hooi, L, Jardine, M, Jun, M, Rogers, K, Sukkar, L, Smyth, B & Gallagher, M 2023, 'Comparing survival in patients with chronic kidney disease across three countries – Results from the study of heart and renal protection‐extended review', Nephrology, vol. 28, no. 1, pp. 36-43.
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AbstractAimThis study examined whether survival and causes of death differed between participants enrolled from Australia (AUS), Malaysia (MYL), and New Zealand (NZ) in extended follow‐up of the Study of Heart and Renal Protection (SHARP), a randomized controlled trial (RCT) of participants with moderate to severe chronic kidney disease comparing placebo to combination therapy with Simvastatin and Ezetimibe.MethodsAll participants alive at final SHARP study visit in participating centres were eligible for inclusion. Consenting participants were re‐enrolled following final SHARP Study visit and followed for 5 years. Data collection included: significant medical events, hospital admissions and requirement for kidney replacement therapy. Data linkage was performed to national kidney and mortality registries. The primary outcome was all‐cause mortality compared across the three countries.ResultsThe SHARP trial randomized 2029 participants from AUS (1043/2029, 51%), MYL (701/2029, 35%), and NZ (285/2029, 14%), with 1136 participants alive and eligible for extended follow‐up at the end of SHARP. In multivariable analysis, risk of death was increased for participants in MYL (HR 1.37, 95% CI 1.17–1.61, p < .001) and NZ (HR 1.28, 95% CI 1.04–1.57, p = .02) when compared to AUS participants. Adjustment for kidney transplantation as a competing risk did not explain the variation seen between countries.ConclusionThis study allows a better understanding of the differences in long‐term mortality risk across participants from AUS, MYL, and NZ in extended follow‐up of the SHARP study and demonstrates the feasibility and value of extended follow‐up of participan...

Tang, SM, Zhang, XJ, Wang, YM, Zhang, Y, Wong, LM, Chan, H-N, Zhang, BN, Chu, WK, Kam, KW, Young, AL, Tham, CC, Chen, LJ, French, AN, Rose, KA, Pang, CP & Yam, JC 2023, 'Effect of Myopic Undercorrection on Habitual Reading Distance in Schoolchildren: The Hong Kong Children Eye Study', Ophthalmology and Therapy, vol. 12, no. 2, pp. 925-938.
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Teirlinck, CH, Verhagen, AP, van Ravesteyn, LM, Reijneveld-van de Vendel, EAE, Runhaar, J, van Middelkoop, M, Ferreira, ML & Bierma-Zeinstra, SMA 2023, 'Effect of exercise therapy in patients with hip osteoarthritis: A systematic review and cumulative meta-analysis', Osteoarthritis and Cartilage Open, vol. 5, no. 1, pp. 100338-100338.
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Tessier, A, Croteau, C, Le Dorze, G, Power, E & Weiss, M 2023, 'Exploring the effects of a communication partner training programme for adapted transport drivers', Aphasiology, vol. 37, no. 2, pp. 179-204.
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Thomson-Casey, C, McIntyre, E, Rogers, K & Adams, J 2023, 'The relationship between psychology practice and complementary medicine in Australia: Psychologists’ demographics and practice characteristics regarding type of engagement across a range of complementary medicine modalities', PLOS ONE, vol. 18, no. 5, pp. e0285050-e0285050.
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IntroductionMany people with mental health problems utilise a range of complementary medicine (CM) practitioners, products, and practices. Psychologists are likely to consult with clients who are seeking and using CM, in some form, as part of their wider mental health treatment. The aim of this research is to determine how much, and in what ways, Australian psychologists recommend CM products and/or practices, and/or initiate referrals to CM practitioners as part of their clinical practice and to explore if these behaviours have any association with the characteristics of the psychologist or their wider practice.MethodsSurvey data was collected from psychologists in clinical practice who self-selected to participate between February and April 2021. Participation in the study was via an online 79-item questionnaire exploring core aspects of CM engagement in psychology clinical practice.ResultsAmongst the 202 psychologists who completed the survey, mind/body approaches (90.5%) were the most recommended CM and cultural/spiritual approaches the least recommended CM (7.5%). Participants also reported referring to CM practitioners with naturopaths the most common focus of their referrals (57.9%) and cultural and spiritual practitioners the least common focus of their referrals (6.69%). Our analysis shows the demographic and practice characteristics of a psychologist are generally not predictors of a psychologist’s engagement with CM in their clinical practice.ConclusionsSubstantial numbers of psychologists recommend CM products and practices and/or refer clients to CM practitioners. Alongside subjecting CM interventions for mental health to an evidence-base assessment, t...

Tiller, JM, Cousens, NE, Kaur, R, Rowley, S, Ko, Y-A, Mahale, S, Bankier, A, Meiser, B, Barlow-Stewart, K, Burnett, L, Jacobs, C, James, P, Trainer, A, Neil, S, Campbell, IG, Andrews, L & Delatycki, M 2023, 'Population-basedBRCA1/2testing programmes are highly acceptable in the Jewish community: results of the JeneScreen Study', Journal of Medical Genetics, vol. 60, no. 3, pp. 265-273.
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BackgroundAshkenazi Jewish (AJ) people have a higher incidence ofBRCA1/2pathogenic variants (PVs) than unselected populations. ThreeBRCA-Jewish founder mutations (B-JFMs) comprise >90% ofBRCA1/2PVs in AJ people. Personal/family cancer history-based testing misses ≥50% of people with B-JFM.MethodsWe compared two population-based B-JFM screening programmes in Australia—using (1) an online tool (Sydney) and (2) in-person group sessions (Melbourne).ResultsOf 2167 Jewish people tested (Sydney n=594; Melbourne n=1573), 1.3% (n=28) have a B-JFM, only 2 of whom had a significant cancer family history (Manchester score ≥12). Pretest anxiety scores were normal (mean 9.9±3.5 (6–24)), with no significant post-result change (9.5±3.3). Decisional regret (mean 7.4±13.0 (0–100)), test-related distress (mean 0.8+/2.2 (0–30)) and positive experiences (reverse-scored) (mean 3.4±4.5 (1–20)) scores were low, with no significant differences between Sydney and Melbourne participants. Post-education knowledge was good overall (mean 11.8/15 (±2.9)) and significantly higher in Melbourne than Sydney. Post-result knowledge was the same (mean 11.7 (±2.4) vs 11.2 (±2.4)). Participants with a B-JFM had higher post-result anxiety and test-related distress and lower positive experiences, than those without a B-JFM, but scores were within the normal range. Family cancer history did not significantly affect knowledge or anxiety, or pretest perception of B-JFM or cancer risks. Most participants (93%) were satisfied/very satisfied with the programme.ConclusionBoth B-JFM screening programmes are highly acceptable to Australian Jewish communities. The programme enabled identificati...

Tjokrowijoto, P, Stolwyk, RJ, Ung, D, Kneebone, I, Kilkenny, MF, Kim, J, Olaiya, MT, Dalli, LL, Cadilhac, DA, Nelson, MR, Lannin, NA & Andrew, NE 2023, 'Receipt of Mental Health Treatment in People Living With Stroke: Associated Factors and Long-Term Outcomes', Stroke, vol. 54, no. 6, pp. 1519-1527.
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Background: Untreated poststroke mood problems may influence long-term outcomes. We aimed to investigate factors associated with receiving mental health treatment following stroke and impacts on long-term outcomes. Methods: Observational cohort study derived from the Australian Stroke Clinical Registry (AuSCR; Queensland and Victorian registrants: 2012–2016) linked with hospital, primary care billing and pharmaceutical dispensing claims data. Data from registrants who completed the AuSCR 3 to 6 month follow-up survey containing a question on anxiety/depression were analyzed. We assessed exposures at 6 to 18 months and outcomes at 18 to 30 months. Factors associated with receiving treatment were determined using staged multivariable multilevel logistic regression models. Cox proportional hazards regression models were used to assess the impact of treatment on outcomes. Results: Among 7214 eligible individuals, 39% reported anxiety/depression at 3 to 6 months following stroke. Of these, 54% received treatment (88% antidepressant medication). Notable factors associated with any mental health treatment receipt included prestroke psychological support (odds ratio [OR], 1.80 [95% CI, 1.37–2.38]) or medication (OR, 17.58 [95% CI, 15.05–20.55]), self-reported anxiety/depression (OR, 2.55 [95% CI, 2.24–2.90]), younger age (OR, 0.98 [95% CI, 0.97–0.98]), and being female (OR, 1.30 [95% CI, 1.13–1.48]). Those who required interpreter services (OR, 0.49 [95% CI, 0.25–0.95]) used a health benefits card (OR, 0.73 [95% CI, 0.59–0.92]) or had continuity of primary care visits (ie, with a consistent physician; OR, 0.78 [95% CI, 0.62–0.99]) were less likely to access mental health services....

Togher, L, Elbourn, E, Kenny, B, Honan, C, Power, E, Tate, R, McDonald, S & MacWhinney, B 2023, 'Communication and Psychosocial Outcomes 2-Years After Severe Traumatic Brain Injury: Development of a Prognostic Model', Archives of Physical Medicine and Rehabilitation, vol. 104, no. 11, pp. 1840-1849.
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OBJECTIVE: To examine predictive factors underlying communication and psychosocial outcomes at 2 years post-injury. Prognosis of communication and psychosocial outcomes after severe traumatic brain injury (TBI) is largely unknown yet is relevant for clinical service provision, resource allocation, and managing patient and family expectations for recovery. DESIGN: A prospective longitudinal inception design was employed with assessments at 3 months, 6 months, and 2 years. PARTICIPANTS: The cohort included 57 participants with severe TBI (N=57). SETTING: Subacute and post-acute rehabilitation. MAIN OUTCOME MEASURES: Preinjury/injury measures included age, sex, education years, Glasgow Coma Scale, and PTA. The 3-month and 6-month data points included speech, language, and communication measures across the ICF domains and measures of cognition. The 2-year outcome measures included conversation, perceived communication skills, and psychosocial functioning. Predictors were examined using multiple regression. INTERVENTIONS: Not applicable. RESULTS: The cognitive and communication measures at 6 months significantly predicted conversation measures at 2 years and psychosocial functioning as reported by others at 2 years. At 6 months, 69% of participants presented with a cognitive-communication disorder (Functional Assessment of Verbal Reasoning and Executive Strategies [FAVRES]). The unique variance accounted for by the FAVRES measure was 7% for conversation measures and 9% for psychosocial functioning. Psychosocial functioning at 2 years was also predicted by pre-injury/injury factors and 3-month communication measures. Pre-injury education level was a unique predictor, accounting for 17% of the variance, and processing speed/memory at 3 months uniquely accounted for 14% of the variance. CONCLUSION: Cognitive-communication skills at 6 months are a potent predictor of persisting communication challenges and poor psychosocial outcomes up to 2 years after a severe ...

Trebilcock, M, Shrubsole, K, Worrall, L & Ryan, B 2023, 'A survey of speech pathologists’ opinions about the prospective acceptability of an online implementation platform for aphasia services', International Journal of Language & Communication Disorders, vol. 58, no. 2, pp. 390-405.
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AbstractBackgroundOnline knowledge translation (KT) approaches are becoming increasingly prevalent within healthcare due to their accessibility and facilitation of international support networks. Online platforms enable timely and far‐reaching dissemination of current evidence and best‐practice recommendations. Although there is potential to improve the uptake of rehabilitation guidelines, it is essential to consider the acceptability of online approaches to healthcare professionals to ensure their successful integration within everyday clinical settings.AimsTo establish the prospective acceptability of a theoretically informed online intervention for speech pathologists, Aphasia Nexus: Connecting Evidence to Practice, that aims to facilitate the implementation of aphasia best practice.Methods & ProceduresA mixed‐methods multinational electronic survey based on the Theoretical Framework of Acceptability (TFA) completed by aphasia researchers and clinicians.Outcomes & ResultsA total of 43 participants completed the survey with 91% (n = 39) indicating that they would use Aphasia Nexus. Understanding the intervention and how it works (intervention coherence as per the TFA) was the key factor influencing the likelihood of integration within everyday clinical practice. Participants identified potential areas where the intervention could influence service change and also recommended further design and content changes to improve the intervention.Conclusions & ImplicationsAphasia Nexus is an acceptable ...

Turbitt, E, Bourne, M, McEwen, A & Amor, DJ 2023, 'Parents' preferences for receiving and discussing prognostic genetic information regarding their children's neurodevelopmental condition: A qualitative study', Developmental Medicine & Child Neurology.
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AbstractAimTo investigate parents' preferences and motivations for receiving and discussing prognostic genetic test results.MethodWe used a cross‐sectional, interpretive description qualitative study design. We collected data through semi‐structured interviews with Australian parents, which we analysed using reflexive thematic analysis.ResultsParents (n = 32) had a child or children with a genetic neurodevelopmental condition, such as fragile X syndrome, DiGeorge (22q11.2 deletion) syndrome, or Angelman syndrome. Parents of mildly impacted or older children were tolerant to prognostic uncertainty. Parents found conversations about their child's prognosis emotional and preferred to discuss their child's potential strengths and challenges. While most were enthusiastic about prognostic tests and described many motivations for testing, the potential for prognostic information to contribute to a loss of hope and stigmatizing societal views were also discussed.InterpretationParents had mixed preferences and motivations for acquiring prognostic genetic information about their child, contrasting evidence in other contexts such as cancer where parents typically have minimal tolerance of uncertainty. Health professionals should consider strength‐based framing of prognostic information gained from current and emerging technologies when returning results to families.

Turbitt, E, Jacobs, C & McEwen, A 2023, 'Special Issue: “Genetic Counseling and Genetic Testing in Precision Medicine”', Journal of Personalized Medicine, vol. 13, no. 8, pp. 1192-1192.
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Progress in genomic technologies has spurred innovation in healthcare and medicine, contributing to improved health and well-being [...]

Turbitt, E, Kohler, JN, Angelo, F, Miller, IM, Lewis, KL, Goddard, KAB, Wilfond, BS, Biesecker, BB & Leo, MC 2023, 'The PrU: Development and validation of a measure to assess personal utility of genomic results', Genetics in Medicine, vol. 25, no. 3, pp. 100356-100356.
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Turnbull, H, Dark, L, Carnemolla, P, Skinner, I & Hemsley, B 2023, 'A systematic review of the health literacy of adults with lifelong communication disability: Looking beyond accessing and understanding information', Patient Education and Counseling, vol. 106, pp. 151-162.
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OBJECTIVE: To determine the a) extent to which people with lifelong communication disability are included in health literacy research, b) level of health literacy of people with lifelong communication disability, c) methods applied to measure the health literacy of people with lifelong communication disability, d) barriers and facilitators mediating the health literacy of people with lifelong communication disability, and e) outcomes of health literacy interventions for people with lifelong communication disability. METHODS: We searched for studies relating to health literacy, people with lifelong communication disability, and key areas of the Sørensen et al. (2012) health literacy model (i.e., accessing, understanding, appraising, applying health information, personal/environmental/systemic barriers and facilitators). RESULTS: Analysis of 60 studies demonstrated that this population is not well represented. Insufficient research exists to inform statements on level of health literacy or methods used to measure health literacy of this population. Barriers and facilitators appear consistent with those applicable to the general population. Health literacy intervention outcomes were variable. CONCLUSION: Significant gaps exist in the research which has primarily focused on people with intellectual disability accessing and understanding health information. PRACTICE IMPLICATIONS: Findings can inform policies, practice, and future research on health literacy and people with lifelong communication disability.

Tyler, C, Finch, E, Shrubsole, K, Ryan, B, Soroli, E, Martinez-Ferreiro, S & Wallace, SJ 2023, 'Aphasia outcome measurement in clinical practice: An international survey', Aphasiology, vol. 37, no. 10, pp. 1576-1593.
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Urionagüena, A, Piquer-Martinez, C, Gastelurrutia, MÁ, Benrimoj, SI, Garcia-Cardenas, V, Fernandez-Llimos, F, Martinez-Martinez, F & Calvo, B 2023, 'Community pharmacy and primary health care - Types of integration and their applicability: A narrative review', Research in Social and Administrative Pharmacy, vol. 19, no. 3, pp. 414-431.
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Vears, DF, Boyle, J, Jacobs, C, McInerney-Leo, A & Newson, AJ 2023, 'Human Genetics Society of Australasia Position Statement: Genetic Carrier Testing for Recessive Conditions', Twin Research and Human Genetics, vol. 26, no. 2, pp. 188-194.
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AbstractThis Position Statement provides guidelines to assist all health professionals who receive requests for carrier testing and laboratory staff conducting the tests.In this Statement, the term ‘carrier testing’ refers to genetic testing in an individual to determine whether they have inherited a pathogenic variant associated with an autosomal or X-linked recessive condition previously identified in a blood relative. Carrier testing recommendations: (1) Carrier testing should only be performed with the individual’s knowledge and consent; (2) An individual considering (for themselves, or on behalf of another) whether to have a carrier test should be supported to make an informed decision; (3) The mode of inheritance, the individual’s personal experience with the condition, and the healthcare setting in which the test is being performed should be considered when determining whether carrier testing should be offered by a genetic health professional. Regarding children and young people: Unless there is direct medical benefit in the immediate future, the default position should be to postpone carrier testing until the child or young person can be supported to make an informed decision. There may be some specific situations where it is appropriate to facilitate carrier testing in children and young people (see section in this article). In such cases, testing should only be offered with pre- and post-test genetic counseling in which genetic health professionals and parents/guardians should explore the rationale for testing and the interests of the child and the family.

Verhagen, A & Saragiotto, BT 2023, 'Tips and tricks to improve your systematic review manuscript', Musculoskeletal Science and Practice, vol. 65, pp. 102769-102769.
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Verhagen, AP & Leaver, AM 2023, 'Invited commentary on: Risk assessment of vascular complications following manual therapy and exercise for the cervical region: diagnostic accuracy of the International Federation of Orthopaedic Manipulative Physical Therapists framework (The Go4Safe project) by de Best et al.', Journal of Physiotherapy, vol. 69, no. 4, pp. 267-267.
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Verhagen, AP, Brown, H, Hancock, M & Anderson, D 2023, 'Test procedures and positive diagnostic criteria of the upper limb tension tests differ: a systematic review of the DiTA database', Brazilian Journal of Physical Therapy, vol. 27, no. 6, pp. 100558-100558.
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Verhagen, AP, Mehta, P, Hildenbrand, C, Pace, J, Nasser, A & McCambridge, AB 2023, 'Can clinicians find conservative management protocols of anterior cruciate ligament injuries online? A systematic review', Musculoskeletal Science and Practice, vol. 67, pp. 102841-102841.
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Verhagen, AP, Mehta, P, Hildenbrand, C, Pace, J, Nasser, A & McCambridge, AB 2023, 'Can patients and clinicians find conservative management protocols of anterior cruciate ligament injuries online? A systematic review', Musculoskeletal Science and Practice, vol. 65, pp. 102754-102754.
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Wallace, SJ, Worrall, L, Rose, TA, Alyahya, RSW, Babbitt, E, Beeke, S, de Beer, C, Bose, A, Bowen, A, Brady, MC, Breitenstein, C, Bruehl, S, Bryant, L, Cheng, BBY, Cherney, LR, Conroy, P, Copland, DA, Croteau, C, Cruice, M, Dipper, L, Hilari, K, Howe, T, Kelly, H, Kiran, S, Laska, A, Marshall, J, Murray, LL, Patterson, J, Pearl, G, Quinting, J, Rochon, E, Rose, ML, Rubi‐Fessen, I, Sage, K, Simmons‐Mackie, N, Visch‐Brink, E, Volkmer, A, Webster, J, Whitworth, A & Dorze, GL 2023, 'Measuring communication as a core outcome in aphasia trials: Results of the ROMA‐2 international core outcome set development meeting', International Journal of Language & Communication Disorders, vol. 58, no. 4, pp. 1017-1028.
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AbstractBackgroundEvidence‐based recommendations for a core outcome set (COS; minimum set of outcomes) for aphasia treatment research have been developed (the Research Outcome Measurement in Aphasia—ROMA, COS). Five recommended core outcome constructs: communication, language, quality of life, emotional well‐being and patient‐reported satisfaction/impact of treatment, were identified through three international consensus studies. Constructs were paired with outcome measurement instruments (OMIs) during an international consensus meeting (ROMA‐1). Before the current study (ROMA‐2), agreement had not been reached on OMIs for the constructs of communication or patient‐reported satisfaction/impact of treatment.AimTo establish consensus on a communication OMI for inclusion in the ROMA COS.Methods & ProceduresResearch methods were based on recommendations from the Core Outcome Measures in Effectiveness Trials (COMET) Initiative. Participants with expertise in design and conduct of aphasia trials, measurement instrument development/testing and/or communication outcome measurement were recruited through an open call. Before the consensus meeting, participants agreed on a definition of communication, identified appropriate OMIs, extracted their measurement properties and established criteria for their quality assessment. During the consensus meeting they short‐listed OMIs and participants without conflicts of interest voted on the two most highly ranked instruments. Consensus was defined a priori as agreement by ≥ 70% of participants.Outcomes & ResultsIn total, 40 researchers from nine countries participated in ROMA‐2 (including four facilitators and three‐panel members who participated in pre‐meeting ...

Wallingford, C, Kovilpillai, H, Jacobs, C, Turbitt, E, Primiero, C, Brockman, D, Soyer, HP, McInerney-Leo, A & Yanes, T 2023, 'Models of communication for polygenic scores and associated behavioural and psychological outcomes: a systematic review', EUROPEAN JOURNAL OF HUMAN GENETICS, vol. 31, pp. 674-674.

Wallingford, CK, Kovilpillai, H, Jacobs, C, Turbitt, E, Primiero, CA, Young, M-A, Brockman, DG, Soyer, HP, McInerney-Leo, AM & Yanes, T 2023, 'Models of communication for polygenic scores and associated psychosocial and behavioral effects on recipients: A systematic review', Genetics in Medicine, vol. 25, no. 1, pp. 1-11.
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PURPOSE: This study aimed to systematically review current models for communicating polygenic scores (PGS) and psycho-behavioral outcomes of receiving PGSs. METHODS: Original research on communicating PGSs and reporting on psycho-behavioral outcomes was included. Search terms were applied to 5 databases and were limited by date (2009-2021). RESULTS: In total, 28 articles, representing 17 studies in several disease settings were identified. There was limited consistency in PGS communication and evaluation/reporting of outcomes. Most studies (n = 14) presented risk in multiple ways (ie, numerically, verbally, and/or visually). Three studies provided personalized lifestyle advice and additional resources. Only 1 of 17 studies reported using behavior change theory to inform their PGS intervention. A total of 8 studies found no evidence of long-term negative psychosocial effects up to 12 months post result. Of 14 studies reporting on behavior, 9 found at least 1 favorable change after PGS receipt. When stratified by risk, 7 out of 9 studies found high PGS was associated with favorable changes including lifestyle, medication, and screening. Low-risk PGS was not associated with maladaptive behaviors (n = 4). CONCLUSION: PGS has the potential to benefit health behavior. High variability among studies emphasizes the need for developing standardized guidelines for communicating PGSs and evaluating psycho-behavioral outcomes. Our findings call for development of best communication practices and evidence-based interventions informed by behavior change theories.

Watson, P & Mahlberg, J 2023, 'Mechanisms underlying performance in a cued go/no-go Pavlovian-to-instrumental transfer paradigm', Behavioural Brain Research, vol. 446, pp. 114413-114413.
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Environmental cues that remind us of rewarding outcomes (drugs, food) play a significant role in addiction relapse. In the lab the Pavlovian-to-instrumental transfer (PIT) task has been used to formally examine how cues associated with reward or punishment can bias ongoing instrumental responding. Using a version of this paradigm that integrates PIT with a go/no-go task many studies have related stronger PIT effects (with non-drug rewards) to problematic alcohol use including risky alcohol users relative to non-risky drinkers, individuals with alcohol dependence versus healthy controls and individuals in recovery from alcohol use disorder who are more likely to relapse. However the theoretical importance of these findings and the implications for models of addiction was previously not clear. Understanding if this task indexes the general motivating effects of reward cues on instrumental responding (and whether this is sensitive to shifts in motivation for those outcomes) is critical for understanding these previous results within the context of addiction. Thus, in the current study we aimed to delineate the associative mechanisms that drive the stimulus effects observed in this PIT task. Specifically, we wished to examine whether the cueing effects observed in the cued-go/no-go task were selective in their effect on action, insofar as Pavlovian cues specifically invigorated (or suppressed) responding only if they were associated with congruent outcomes. We conclude that the PIT measured with this task is general in nature. Surprisingly however, the biasing effects of Pavlovian cues on instrumental responding did not appear to be sensitive to outcome devaluation.

Watson, P & Onie, S 2023, 'Images of Australian alcoholic and non-alcoholic beverages: A validation dataset', Data in Brief, vol. 47, pp. 108914-108914.
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Watson, P, Gladwin, TE, Verhoeven, AAC & de Wit, S 2023, 'Investigating habits in humans with a symmetrical outcome-revaluation task', Behavior Research Methods, vol. 55, no. 5, pp. 2687-2705.
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AbstractThe translation of the outcome-devaluation paradigm to study habit in humans has yielded interesting insights but proven to be challenging. We present a novel, outcome-revaluation task with a symmetrical design, in the sense that half of the available outcomes are always valuable and the other half not-valuable. In the present studies, during the instrumental learning phase, participants learned to respond (Go) to certain stimuli to collect valuable outcomes (and points) while refraining to respond (NoGo) to stimuli signaling not-valuable outcomes. Half of the stimuli were short-trained, while the other half were long-trained. Subsequently, in the test phase, the signaled outcomes were either value-congruent with training (still-valuable and still-not-valuable), or value-incongruent (devalued and upvalued). The change in outcome value on value-incongruent trials meant that participants had to flexibly adjust their behavior. At the end of the training phase, participants completed the self-report behavioral automaticity index – providing an automaticity score for each stimulus-response association. We conducted two experiments using this task, that both provided evidence for stimulus-driven habits as reflected in poorer performance on devalued and upvalued trials relative to still-not-valuable trials and still-valuable trials, respectively. While self-reported automaticity increased with longer training, behavioral flexibility was not affected. After extended training (Experiment 2), higher levels of self-reported automaticity when responding to stimuli signaling valuable outcomes were related to more ‘slips of action’ when the associated outcome was subsequently devalued. We conclude that the symmetrical outcome-revaluation task provides a promising paradigm for the experimental investigation of habits in humans.

Watson, PK, Eitivipart, AC, Davis, GM, Arora, M, Middleton, JW & De Oliveira, CQ 2023, 'Effects of behaviour change interventions on physical activity in people with spinal cord injury: A systematic review and meta-analysis', Psychology of Sport and Exercise, vol. 67, pp. 102408-102408.
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White, S, Haas, M, Laginha, K-J, Laurendet, K, Gaff, C, Vears, D & Newson, AJ 2023, 'What's in a name? Justifying terminology for genomic findings beyond the initial test indication: A scoping review', Genetics in Medicine, vol. 25, no. 11, pp. 100936-100936.
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Genome sequencing can generate findings beyond the initial test indication that may be relevant to a patient or research participant's health. In the decade since the American College of Medical Genetics and Genomics published its recommendations for reporting these findings, consensus regarding terminology has remained elusive and a variety of terms are in use globally. We conducted a scoping review to explore terminology choice and the justifications underlying those choices. Documents were included if they contained a justification for their choice of term(s) related to findings beyond the initial genomic test indication. From 3571 unique documents, 52 were included, just over half of which pertained to the clinical context (n = 29, 56%). We identified four inter-related concepts used to defend or oppose terms: expectedness of the finding, effective communication, relatedness to the original test indication, and how genomic information was generated. A variety of justifications were used to oppose the term 'incidental,' whereas 'secondary' had broader support as a term to describe findings deliberately sought. Terminology choice would benefit from further work to include the views of patients. We contend that clear definitions will improve ethical debate and support communication about genomic findings beyond the initial test indication.

White, S, McErlean, G, Virdun, C, Phillips, JL & Jacobs, C 2023, 'Integrating Genomics into the Care of People with Palliative Needs: A Global Scoping Review of Policy Recommendations', Public Health Genomics, vol. 26, no. 1, pp. 1-15.
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<b><i>Background:</i></b> Genomics has growing relevance to palliative care, where testing largely benefits relatives. Integrating genomics into palliative care has not received the critical attention it requires. Health professionals report a lack of policy guidance to support them to overcome practice barriers to identify palliative patients who are eligible for genetic testing, provide genetic counselling, and facilitate genetic testing or DNA storage. <b><i>Summary:</i></b> To identify policy recommendations related to (1) integrating genomics into the care of patients with palliative care needs and their families and (2) care of the family unit, we performed a scoping review of palliative care and genomic policies. Two of 78 policies recommended integrating genomics into palliative care. Six palliative care policies mentioned genomics in background information but were without relevant recommendations. No genomic policies mentioned palliative care in the background information. Across all policies, “delivering family centred care” was the most frequent recommendation related to care of the family unit (<i>n</i> = 62/78, 79.5%). <b><i>Key Messages:</i></b> We identified a policy gap related to integrating genomics into palliative care. Without policy guidance, health services are less likely to commit funding towards supporting health professionals. Without funding, delivering the benefits of genomics to patients and relatives is more difficult for health professionals. Framing recommendations about genomics as family centred care may resonate with genomic and palliative care stakeholders. These findings highlight an opportunity to improve the policy landscape and access to genomic information for patients with palliative care needs. We call for incorporation of appropriate recommendations into palliative care and genomic policy.

White, S, Mossfield, T, Fleming, J, Barlow-Stewart, K, Ghedia, S, Dickson, R, Richards, F, Bombard, Y & Wiley, V 2023, 'Expanding the Australian Newborn Blood Spot Screening Program using genomic sequencing: do we want it and are we ready?', European Journal of Human Genetics, vol. 31, no. 6, pp. 703-711.
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AbstractSince the introduction of genome sequencing in medicine, the factors involved in deciding how to integrate this technology into population screening programs such as Newborn Screening (NBS) have been widely debated. In Australia, participation in NBS is not mandatory, but over 99.9% of parents elect to uptake this screening. Gauging stakeholder attitudes towards potential changes to NBS is vital in maintaining this high participation rate. The current study aimed to determine the knowledge and attitudes of Australian parents and health professionals to the incorporation of genomic sequencing into NBS programs. Participants were surveyed online in 2016 using surveys adapted from previous studies. The majority of parents (90%) self-reported some knowledge of NBS, with 77% expressing an interest in NBS using the new technology. This was significantly lower than those who would utilise NBS using current technologies (99%). Although, many health professionals (62%) felt that new technologies should currently not be used as an adjunct to NBS, 79% foresaw the use of genomic sequencing in NBS by 2026. However, for genomic sequencing to be considered, practical and technical challenges as well as parent information needs were identified including the need for accurate interpretation of data; pre-and post-test counselling; and appropriate parental consent and opt-out process. Therefore, although some support for implementing genomic sequencing into Australian NBS does exist, there is a need for further investigation into the ethical, social, legal and practical implications of introducing this new technology as a replacement to current NBS methods.

White, S, Turbitt, E, Phillips, JL & Jacobs, C 2023, 'Approaching discussions about genetics with palliative patients and their families: a qualitative exploration with genetic health professionals', European Journal of Human Genetics, vol. 31, no. 8, pp. 945-952.
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AbstractGenetic information can provide clinical benefits to families of palliative patients. However, integration of genetics into mainstream medicine has not focused on palliative populations. We explored the views and experiences of genetic health professionals in addressing genetics with palliative patients, and their families. We conducted an interpretive descriptive qualitative study with genetic counsellors and clinical geneticists using interviews and focus groups. Findings were generated using reflexive thematic analysis. Three themes were identified: (1) Focusing on the benefit to the family, (2) The discomfort of addressing genetics near end-of-life and (3) “It’s always on the back-burner”: Challenges to getting genetics on the palliative care agenda. Participants discussed the familial benefit of genetics in palliative care alongside the challenges when patients are near end-of-life. They perceived genetics as low priority for palliative care due to misunderstandings related to the value of genetic information. Acknowledging the challenges in the palliative care context, genetic health professionals want improved service leadership and awareness of the familial benefits of palliative genetic testing. Strong leadership to support genetic health professionals in addressing these barriers is needed for the benefits of genetic information to be realised.

Wiggins, M, McEwen, A & Sexton, A 2023, 'Young-onset dementia: A systematic review of the psychological and social impact on relatives', Patient Education and Counseling, vol. 107, pp. 107585-107585.
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OBJECTIVE: Young-onset dementia (YOD) has significant impact for the affected person, but also has far-reaching effects on the family. Additionally, biological relatives have an increased genetic risk of developing the condition themselves. This review aimed to identify the psychological and social impacts of YOD in the family, for asymptomatic relatives. METHODS: A systematic review of key databases for empirical studies about the lived experience of biological relatives at risk for YOD was performed. Data was collated and interpreted via narrative synthesis. RESULTS: The majority of the nineteen included studies were qualitative and explored the experiences of children with a parent with YOD. Five themes were developed: (1) Onset of YOD disrupts family functioning (2) Emotional impact is significant and varied (3) Uncertain future (due to uncertainty of diagnosis, care-giving responsibilities, and their own increased genetic risk) (4) Lack of visibility in health care and society (5) Coping strategies include physical/cognitive distancing, and emotion-focused coping. CONCLUSION: Our findings demonstrate a diagnosis of YOD significantly impacts the lives of relatives, yet their experiences and needs often go unnoticed. PRACTICE IMPLICATIONS: We present a practical framework of questions and strategies for care of relatives, mapped to the self-regulation model of genetic counselling.

Wilding, M, Fleming, J, Moore, K, Crook, A, Reddy, R, Choi, S, Schlub, TE, Field, M, Thiyagarajan, L, Thompson, J & Berman, Y 2023, 'Clinical and imaging modality factors impacting radiological interpretation of breast screening in young women with neurofibromatosis type 1', Familial Cancer, vol. 22, no. 4, pp. 499-511.
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Wilkin, T, Stott, A, Lin, JL, Pate, J, McEwen, A, Verhagen, A & Turbitt, E 2023, 'Free Online Decision Tools to Support Parents Making Decisions About Their Children's Chronic Health Condition: An Environmental Scan', Academic Pediatrics, vol. 23, no. 5, pp. 874-883.
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BACKGROUND: Medical decisions parents make on their children's behalf can be challenging. Free online decision support tools are created to help parents faced with these decisions. OBJECTIVE: We used an environmental scan to identify free, online tools that support parents in making decisions about their children's chronic health condition. We described the tools and assessed their potential to harm, content, development process, readability, and whether their use changed decision makers' knowledge and alignment of their preferences with their final decision. DATA SOURCES AND ELIGIBILITY: Decision aid repositories, Google searches, and key informants identified decision support tools. Eligible tools were freely available online and for parents of children with chronic health conditions. APPRAISAL METHODS: Two reviewers independently assessed the tools' quality based on the International Patient Decision Aid Standards (IPDAS). Tool readability was assessed using the Flesch Reading Ease test. RESULTS: From 21 free, online decision support tools, 14 (67%) provided sufficient detail for making a specific decision (IPDAS qualifying criteria). None sufficiently met IPDAS certification criteria necessary to reduce the possibility of patient harms when using the tool. Three (14%) were fairly easy or easy to read. Of those evaluated by developers (n = 6), 2 improved knowledge and 4 improved alignment of preferences with the available options. LIMITATIONS: Google searches and key informant sources are not replicable. CONCLUSIONS: Free, online decision support tools for parents of children with chronic health conditions are of variable quality, most are difficult to read, and there is limited evidence their use achieves intended outcomes. REGISTRATION NUMBER: Registered with Open Science Framework 20 July 2021(AEST) osf.io/b94yj.

Wilson, EJ, Abbott, MJ & Norton, AR 2023, 'The impact of psychological treatment on intolerance of uncertainty in generalized anxiety disorder: A systematic review and meta-analysis', Journal of Anxiety Disorders, vol. 97, pp. 102729-102729.
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Winter, HR, Norton, A & Wootton, BM 2023, 'Internet videoconferencing delivered cognitive behavioral therapy for social anxiety disoder: Protocol for a randomized controlled trial', Contemporary Clinical Trials, vol. 132, pp. 107298-107298.
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Winter, HR, Norton, AR, Burley, JL & Wootton, BM 2023, 'Remote cognitive behaviour therapy for social anxiety disorder: A meta-analysis', Journal of Anxiety Disorders, vol. 100, pp. 102787-102787.
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Remote cognitive behaviour therapy (CBT) for social anxiety disorder (SAD) has the potential to improve access to treatment by reducing economic, geographic, and psychological barriers. The aim of this study was to use a meta-analytic approach to examine the efficacy of the different remote CBT methods for treating SAD. A systematic electronic database search was used to identify 31 studies (n = 2905; mean age range: 24.73-41.65 years; mean female representation = 60.2 %). Pooled within-group analyses indicated large effect sizes from pre-treatment to post-treatment (Hedges' g = 1.06; 95 % CI: 0.96-1.16) and pre-treatment to follow up (g = 1.18; 95 % CI: 1.03-1.33) for remote CBT. Internet-delivered CBT (g = 1.08; 95 % CI: 0.98-1.19) and application-delivered CBT (g = 1.19; 95 % CI: 0.75-1.64) produced large within-group effect sizes. Bibliotherapy-delivered CBT (g = 0.79; 95 % CI: 0.45-1.13) produced medium within-group effect sizes. Pooled between-group findings indicate that remote CBT treatments were more effective than passive control (g = 0.87; 95 % CI: 0.70-1.03) and non-CBT remote treatments (g = 0.41; 95 % CI: 0.17-0.66), and were at least as effective, or slightly more effective, than face-to-face CBT treatments (g = 0.34; 95 % CI: 0.14-0.54). These findings have important implications for the dissemination of remote and stepped-care treatments for SAD.

Yanes, T, Nathan, V, Wallingford, C, Faragher, R, Nankervis, K, Jacobs, C, Vassos, M, Boyle, F, Carroll, A, Smith, S & McInerney‐Leo, A 2023, 'Australasian genetic counselors' attitudes toward disability and prenatal testing: Findings from a cross‐sectional survey', Journal of Genetic Counseling.
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AbstractDiagnostic genetic testing and non‐invasive prenatal testing (NIPT) for conditions associated with disability are becoming increasingly available to consumers. This genetic information can be used in the disability setting to inform factors such as prognosis, management, and reproductive decision‐making. Genetic counselors (GCs) play an important role in the provision of genetic testing and NIPT, and their attitudes toward disability can influence how genetic information is communicated and shape patients' responses. This study aimed to evaluate and describe Australasian GCs' experience with and attitudes toward disabilities to identify potential biases and training needs. A cross‐sectional survey was distributed to 400 GCs registered with the Human Genetics Society of Australasia. Of the 106 respondents (participation rate: 26%), a significantly greater proportion were more comfortable interacting with individuals with physical disability as compared to intellectual disability (p < 0.001). GCs with personal experiences with disabilities reported significantly greater comfort interacting with people with intellectual disability than those without experience (p = 0.012). Qualitative analysis revealed discomfort was less reflective of bias than inexperience and apprehension about communicating disrespectfully. GCs believed people with disabilities experience discrimination and that having a disability could make a person stronger, wiser, and more motivated. Most GCs viewed prenatal testing for disabilities positively as it allowed for decisions regarding continuing the pregnancy and/or provided opportunity to prepare. Challenges identified for prenatal counseling included negative societal attitudes and the low visibility of disability. GCs felt that ‘personal beliefs’ was the primary factor influencing the decision to terminate a pregnancy affected by disabi...

Yiew, K, Togher, L, Power, E, Brunner, M & Rietdijk, R 2023, 'Differentiating Use of Facial Expression between Individuals with and without Traumatic Brain Injury Using Affectiva Software: A Pilot Study', International Journal of Environmental Research and Public Health, vol. 20, no. 2, pp. 1169-1169.
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This study investigated the feasibility of using an automated facial coding engine, Affectiva (integrated in iMotions, version 8.2), for evaluating facial expression after traumatic brain injury (TBI). An observational cross-sectional study was conducted based on facial expression data from videos of participants with TBI and control participants. The aims were to compare TBI and control groups, and identify confounding factors affecting the data analysis. Video samples of two narrative tasks (personal event and story retell) from ten participants with severe TBI and ten control participants without TBI were analyzed using Affectiva. Automated data on participants’ engagement, smile and brow furrow were compared statistically between and within groups. Qualitative notes for each sample were also recorded. Affectiva detected a higher percentage of time of engagement for TBI participants than for control participants on both tasks. There was also a higher percentage of time of smiling for TBI participants in one task. Within groups, there were no significant differences between the two narrative tasks. Affectiva provides standardized data about facial expression and may be sensitive to detecting change in the use of facial expression after TBI. This study also identified factors to avoid during videorecording to ensure high quality samples for future research.

Young, TK, Hockham, C, Sukkar, L, Kang, A, Jun, M, Foote, C, Baker, J, Rogers, K, Zoungas, S, Cass, A, Sullivan, D & Jardine, MJ 2023, 'Duration and effectiveness of glucose-lowering regimens in the real world management of diabetes: Data from the Australian EXTEND45 Linked Cohort Study', Endocrine and Metabolic Science, vol. 12, pp. 100135-100135.
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Zaga, CJ, Freeman-Sanderson, A, Happ, MB, Hoit, JD, McGrath, BA, Pandian, V, Quraishi-Akhtar, T, Rose, L, Sutt, A-L, Tuinman, PR, Wallace, S, Bellomo, R, Berney, S & Vogel, AP 2023, 'Defining effective communication for critically ill patients with an artificial airway: An international multi-professional consensus', Intensive and Critical Care Nursing, vol. 76, pp. 103393-103393.
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Zempsky, W, Bell, J, Mossali, VM, Kachroo, P & Siddiqui, K 2023, 'Common Selfcare Indications of Pain Medications in Children', Pediatric Drugs, vol. 25, no. 3, pp. 321-341.
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Zhu, HY, Hossain, SN, Jin, C, Singh, AK, Nguyen, MTD, Deverell, L, Nguyen, V, Gates, FS, Fernandez, IG, Melencio, MV, Bell, J-AR & Lin, C-T 2023, 'An investigation into the effectiveness of using acoustic touch to assist people who are blind', PLOS ONE, vol. 18, no. 10, pp. e0290431-e0290431.
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Wearable smart glasses are an emerging technology gaining popularity in the assistive technologies industry. Smart glasses aids typically leverage computer vision and other sensory information to translate the wearer’s surrounding into computer-synthesized speech. In this work, we explored the potential of a new technique known as “acoustic touch” to provide a wearable spatial audio solution for assisting people who are blind in finding objects. In contrast to traditional systems, this technique uses smart glasses to sonify objects into distinct sound auditory icons when the object enters the device’s field of view. We developed a wearable Foveated Audio Device to study the efficacy and usability of using acoustic touch to search, memorize, and reach items. Our evaluation study involved 14 participants, 7 blind or low-visioned and 7 blindfolded sighted (as a control group) participants. We compared the wearable device to two idealized conditions, a verbal clock face description and a sequential audio presentation through external speakers. We found that the wearable device can effectively aid the recognition and reaching of an object. We also observed that the device does not significantly increase the user’s cognitive workload. These promising results suggest that acoustic touch can provide a wearable and effective method of sensory augmentation.

Mankelow, J, Ravindran, D, Graham, A, Suri, S, Pate, JW, Ryan, CG & Martin, D 1970, 'P98 An evaluation of a public health campaign in a high school setting targeting pain related knowledge and beliefs – a mixed methods study', SSM Annual Scientific Meeting, Society for Social Medicine Annual Scientific Meeting Abstracts, BMJ Publishing Group Ltd.
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Mehta, P, DeOliveira, C, Stubbs, P, Nasser, A, Pate, J & Verhagen, A 1970, 'Has the reporting of patient reported outcome measures improved in Physiotherapy clinical trials in six major physiotherapy journals (2000-2018): a meta-research design', APA Physiotherapy conference, Ignite the Future of Physio, Brisbane, Australia.

Mehta, P, Stubbs, P & Verhagen, A 1970, 'Ergonomic interventions for treating work-related complaints of the arm, neck or shoulder in adults', APA Physiotherapy conference, Ignite the Future of Physio, Brisbane, Australia.

Nemcova, K, Berle, D & Shires, A 1970, 'The suicidal mind: Systematic review of cognitive patterns in relation to suicidality', INTERNATIONAL JOURNAL OF PSYCHOLOGY, JOHN WILEY & SONS LTD, pp. 245-245.

Nguyen, M, Zhu, H, Sun, H, Nguyen, V, Deverell, L, Singh, A, Jin, C & Lin, C-T 1970, 'An Evaluation of the Presentation of Acoustic Cues for Shorelining Techniques', 2023 Immersive and 3D Audio: from Architecture to Automotive (I3DA), 2023 Immersive and 3D Audio: from Architecture to Automotive (I3DA), IEEE.
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Sheng, H, Yu, X, Wang, F, Khan, MDW, Weng, H, Shariflou, S & Golzan, SM 1970, 'Autonomous Stabilization of Retinal Videos for Streamlining Assessment of Spontaneous Venous Pulsations', 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2023 45th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), IEEE.
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Shires, A 1970, 'Mindfulness Integrated CBT International Summit', Mindfulness Integrated CBT International Summit. Celebrating 20 years of MiCBT, Australia/online.

Shires, A AIPEP 2023, Guidance in Creating Honours (Fourth Year) and Postgraduate Equity Pathways in Tertiary Psychology for Aboriginal and/or Torres Strait Islander Applicants: A Report from the Equity Pathways Working Group as part of the AIPEP Community of Practice., AIPEP Community of Practice.
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Actkins, KV, Srinivasan, S, Spees, LP, Turbitt, E, Allen, CG & Roberts, MC 2023, 'Data from Uptake of Genetic Testing Among Patients with Cancer At Risk for Lynch Syndrome in the National Health Interview Survey'.
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<div>Abstract<p>Lynch syndrome is the most common inherited cancer syndrome that increases the risk of developing colorectal and endometrial cancer. Universal screening guidelines were first recommended by the Centers for Disease Control and Prevention (CDC) in 2009 and are updated annually by multiple societies. Therefore, one would expect genetic testing rates to increase over time. But testing remains underutilized among those with colorectal or endometrial cancer, even though early detection can improve prognosis and survival rates. In this study, we aimed to understand differences in genetic testing uptake among those with colorectal cancer or endometrial cancer from 2005, 2010, 2015, using data from the National Health Interview Survey (NHIS). We examined genetic testing uptake across cancer-type, age (≤50 or ≥51), sex, race, insurance, and education using a χ² statistical analysis. Despite an upward genetic testing trend in 2010, we found no significant differences in genetic testing uptake over time. In 2010, non-White individuals experienced the highest increase from 2005 in comparison with White individuals. However, genetic testing rates declined for both groups by 2015. Our findings show that genetic testing for colorectal cancer and endometrial cancer did not increase over a 10-year period in spite of guidelines that recommend testing.</p><p><b>Prevention Relevance:</b> Genetic testing uptake for colorectal cancer and endometrial cancer has not increased over a 10-year period in spite of universal screening guidelines. More genetic testing education is needed at the provider and patient level to improve screening strategies for cancer patients who are most at risk for Lynch syndrome.</p></div>

Actkins, KV, Srinivasan, S, Spees, LP, Turbitt, E, Allen, CG & Roberts, MC 2023, 'Data from Uptake of Genetic Testing Among Patients with Cancer At Risk for Lynch Syndrome in the National Health Interview Survey'.
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<div>Abstract<p>Lynch syndrome is the most common inherited cancer syndrome that increases the risk of developing colorectal and endometrial cancer. Universal screening guidelines were first recommended by the Centers for Disease Control and Prevention (CDC) in 2009 and are updated annually by multiple societies. Therefore, one would expect genetic testing rates to increase over time. But testing remains underutilized among those with colorectal or endometrial cancer, even though early detection can improve prognosis and survival rates. In this study, we aimed to understand differences in genetic testing uptake among those with colorectal cancer or endometrial cancer from 2005, 2010, 2015, using data from the National Health Interview Survey (NHIS). We examined genetic testing uptake across cancer-type, age (≤50 or ≥51), sex, race, insurance, and education using a χ² statistical analysis. Despite an upward genetic testing trend in 2010, we found no significant differences in genetic testing uptake over time. In 2010, non-White individuals experienced the highest increase from 2005 in comparison with White individuals. However, genetic testing rates declined for both groups by 2015. Our findings show that genetic testing for colorectal cancer and endometrial cancer did not increase over a 10-year period in spite of guidelines that recommend testing.</p><p><b>Prevention Relevance:</b> Genetic testing uptake for colorectal cancer and endometrial cancer has not increased over a 10-year period in spite of universal screening guidelines. More genetic testing education is needed at the provider and patient level to improve screening strategies for cancer patients who are most at risk for Lynch syndrome.</p></div>

Actkins, KV, Srinivasan, S, Spees, LP, Turbitt, E, Allen, CG & Roberts, MC 2023, 'Supplementary Table S1 and S2 from Uptake of Genetic Testing Among Patients with Cancer At Risk for Lynch Syndrome in the National Health Interview Survey'.
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<p>Supplementary Table S1 shows unweighted descriptive statistics of genetic testing uptake. Supplementary Table S2 shows genetic testing uptake by (1) cancer type and (2) racial groups</p>

Actkins, KV, Srinivasan, S, Spees, LP, Turbitt, E, Allen, CG & Roberts, MC 2023, 'Supplementary Table S1 and S2 from Uptake of Genetic Testing Among Patients with Cancer At Risk for Lynch Syndrome in the National Health Interview Survey'.
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<p>Supplementary Table S1 shows unweighted descriptive statistics of genetic testing uptake. Supplementary Table S2 shows genetic testing uptake by (1) cancer type and (2) racial groups</p>

Alais, D, Coorey, J, Blake, R & Davidson, MJ 2023, 'A new ‘CFS tracking’ paradigm reveals uniform suppression depth regardless of target complexity or salience', Cold Spring Harbor Laboratory.
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Alais, D, Coorey, J, Blake, R & Davidson, MJ 2023, 'tCFS: A new ‘CFS tracking’ paradigm reveals uniform suppression depth regardless of target complexity or salience', eLife Sciences Publications, Ltd.
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Alamil, JMR, Xenaki, D, Manandhar, B, Paudel, KR, Hansbro, PM, Oliver, BG, Chellappan, DK & Dua, K 2023, 'Agarwood oil nanoemulsion attenuates production of lipopolysaccharide (LPS)-induced proinflammatory cytokines, IL-6 and IL-8 in human bronchial epithelial cells.', IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund, pp. 681-685.
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Andrews, NE, Ireland, D, Vijayakumar, P, Burvill, L, Hay, E, Westerman, D, Rose, T, Schlumpf, M, Strong, J & Claus, A 2023, 'Acceptability of a Pain History Assessment and Education Chatbot (Dolores) Across Age Groups in Populations With Chronic Pain: Development and Pilot Testing (Preprint)', JMIR Publications Inc..
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Barnes, L, Davidson, MJ & Alais, D 2023, 'The speed and phase of locomotion dictate saccade probability and simultaneous low-frequency power spectra', Cold Spring Harbor Laboratory.
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Burton, AL, Hatoum, AH, Berry, SL & Hamilton, B 2023, 'Getting into a good headspace: A study protocol of an efficacy trial for an eating disorder prevention program in an Australian youth mental health service', Research Square Platform LLC.
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Clayton, N, Freeman-Sanderson, A & Walker, E 2023, 'Dysphagia prevalence and outcomes associated with the evolution of COVID-19 and its variants', Elsevier BV, pp. S2-S3.
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Clayton, N, Freeman-Sanderson, A & Walker, E 2023, 'Prevalence and recovery of dysphonia in COVID-19 patient requiring Intensive Care treatment: an observational cohort study', Elsevier BV, pp. S3-S3.
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Davidson, MJ, Keys, RT, Szekely, B, MacNeilage, P, Verstraten, F & Alais, D 2023, 'Peripersonal tracking accuracy is limited by the speed and phase of locomotion', Cold Spring Harbor Laboratory.
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Davidson, MJ, Verstraten, FAJ & Alais, D 2023, 'Walking entrains unique oscillations in performance on a visual detection task', Cold Spring Harbor Laboratory.
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De Rubis, G, Paudel, KR & Dua, K 2023, 'Modernizing traditional medicine: nanoparticle-based drug delivery systems to improve the delivery of phytoceuticals in managing chronic respiratory diseases'.

De Rubis, G, Paudel, KR, Liu, G, Hansbro, P, Adams, J, Oliver, B & Dua, K 2023, 'Berberine-loaded nanoparticles attenuate TGF-β-induced remodelling features in human bronchial epithelial cells'.

Dive, L, Archibald, A, Freeman, L & Newson, A 2023, 'Working with 'severity' in reproductive genetic carrier screening', SPRINGERNATURE, pp. 330-330.

Freeman-Sanderson, A & Rose, L 2023, 'Outcomes after Critical Illness', Massachusetts Medical Society, pp. 381-383.
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Hardie, R, Sezgin, G, Pont, LG, Thomas, J, Prgomet, M, McGuire, P, Pearce, C & Georgiou, A 2023, 'Psychotropic medication prescribing for children and adolescents by general practitioners during the COVID‐19 pandemic', Wiley, pp. 26-27.
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Jacobs, C, Turbitt, E, McEwen, A & Atkins, L 2023, 'Exploring Australian genetic counsellors' perceptions and readiness to deliver behaviour change', SPRINGERNATURE, pp. 21-22.

Jenkins, L 2023, 'Prediction and causal inference in the transition from acute to chronic low back pain'.
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The overarching aim of this thesis was to enhance our understanding of the neurobiological risk factors associated with the transition from acute to chronic Low back pain (LBP). To achieve this aim, the Understanding persistent Pain Where it ResiDes (UPWaRD) study was conducted. In this thesis, six chapters describe the background, methods, and results of the UPWaRD study. Chapter 2 describes the protocol, published ‘a priori’ for developing a multivariable prediction model, including candidate predictors selected from the neurobiological (e.g. sensorimotor cortical excitability assessed by sensory and motor evoked potentials, Brain Derived Neurotrophic Factor [BDNF] genotype), psychological (e.g. depression and anxiety), symptom-related (e.g. LBP history) and demographic domains. Chapter 3 builds on the study protocol in the form of a cohort profile, describing baseline characteristics of 120 people experiencing an acute LBP episode and 57 pain-free control participants that form the UPWaRD cohort. Chapter 4 reports the results of the multivariable prediction model developed in 120 people experiencing acute LBP. To further understand the importance of these prognostic factors we developed a causal model of chronic LBP using directed acyclic graphs. The methodology and statistical analysis plan for drawing causal inferences, thus transparently reporting our causal assumptions, are reported in Chapter 5. Chapter 6 then provides the first evidence that low sensory cortex excitability during an acute LBP episode is a causal mechanism underpinning the development of chronic LBP. Finally, in Chapter 7, we report the results of a proteomic analysis, using hydrophobic interaction chromatography and electrospray ionization tandem mass spectrometry. Taken together this thesis makes an extensive and original contribution to our understanding of neurobiological risk factors involved in the transition from acute to chronic LBP. Not only is the inclusion of neurobio...

Koenig-Robert, R, Pace, T, Pearson, J & Hohwy, J 2023, 'Time-resolved hierarchical frequency-tagging reveals markers of predictive processing in the action-perception loop', Authorea, Inc..
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Koenig-Robert, R, Quek, G, Grootswagers, T & Varlet, M 2023, 'Movement trajectories as a window into the dynamics of emerging neural representations', Cold Spring Harbor Laboratory.
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Mohamad, MSB, Reyes, R-J, De Rubis, G, Paudel, KR, Hansbro, PM, Dua, K & Chellappan, DK 2023, 'The versatility of 18ß-glycyrrhetinic acid in attenuating pulmonary inflammatory disorders.', pp. 188-190.
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Narang, P, Haghi, M, Burke, C & Oliver, B 2023, 'Human Upper Respiratory Tract Microbiome and Epithelium Interactions', European Respiratory Society.
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Newson, A & Dive, L 2023, 'Ethical aspects of population scale reproductive genetic carrier screening: Insights from the Mackenzie's Mission project', SPRINGERNATURE, pp. 690-690.

Pandian, V, Freeman-Sanderson, A, McGrath, BA & Brenner, MJ 2023, 'Letter to the Editor: “What matters most to adults with a tracheostomy in ICU and the implications for clinical practice: A qualitative systematic review and metasynthesis.”', Elsevier BV, pp. 154252-154252.
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Paudel, KR, Manandhar, B, Singh, SK, Gupta, G, Hansbro, PM, Chellappan, DK & Dua, K 2023, 'Cytotoxic mechanisms of berberine-phytantriol liquid crystalline nanoparticles against non-small-cell lung cancer.', IfADo - Leibniz Research Centre for Working Environment and Human Factors, Dortmund, pp. 516-519.
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Pickard, K, Davidson, M & Alais, D 2023, 'Visual direction perception is pulled toward direction of head rotation', Center for Open Science.
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Pickard, K, Davidson, M, Kim, S & Alais, D 2023, 'Incongruent active head rotations increase visual motion detection thresholds', Center for Open Science.
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Pierce, JE, Hernandez, N, Alahakoon, D, Adikari, A, Pallewela, N, Sheldrick, T, Hill, AJ, Ryan, B, Wong, D, Copland, D, Power, E, Kneebone, I, Togher, L, Usherwood, T, Shiggins, C, Cadilhac, D, Hill, K, Churilov, L, Worrall, L, Lanyon, L, Attard, M, Rietdijk, R, Lindley, RI & Rose, ML 2023, 'What are the Highest Priority Challenges for People with Communication Disability after Discharge?', SAGE PUBLICATIONS LTD, pp. 29-30.

Rehman, SF, Fuchs, D, Budden, KF, Quaranta, A, Shukla, SD, Horvat, J, Wood, LG, Wheelock, CE & Hansbro, PM 2023, 'Lipid Profiling Reveals Key Lipid Mediators in Cigarette Smoke-induced Experimental COPD', American Thoracic Society, pp. a6148-a6148.
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Shrubsole, K, Power, E, Rogers, K, Wallace, S, McCluskey, A, Isaacs, M & Ong, WX 2023, 'Improving Communication Partner Training of Carers of People with Aphasia: Preliminary Results of a Stepped Wedge Implementation Trial', SAGE PUBLICATIONS LTD, pp. 32-32.

Smith, R, Bryant, L & Hemsley, B 2023, '“No longer a dish served as ‘slop’”: Views on food shaping and 3D food printing to improve mealtime experiences and quality of life for people with dysphagia'.

Smith, R, Bryant, L & Hemsley, B 2023, 'Dysphagia, Quality of Life, and Food Design: An Evidence-Based Model to Guide Inclusive Dysphagia Practice'.

Smith, R, Bryant, L & Hemsley, B 2023, 'More Than a Meal: Building an Evidence-Based Framework of Mealtime-Related Quality of Life, Participation, and Inclusion for People with Swallowing Disability'.

Sun, H, Nguyen, M, Zhu, H, Nguyen, V, Lin, C-T & Jin, C 2023, 'A binaural room impulse response dataset and Shorelining psychophysical task for the evaluation of auditory sensory augmentation', Acoustical Society of America (ASA), pp. A195-A195.
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Sensory augmentation using spatial sound presented in augmented-reality (AR) can assist people with low vision or blindness in navigating their environment (Katz et al., 2012). Nonetheless, in many situations, the poor quality of the binaural sound rendered using current tool sets limits the potential capability of the assistive technology. In particular, acoustic environments with near-field sources and reflections pose significant challenges. In this work, we provide a reference binaural room impulse response (BRIR) dataset with near-field sources and reflections and an associated shorelining psychophysical task that is useful for the evaluation of AR spatial audio. The dataset consists of 12∼small loudspeakers arranged on a 3-by-4 grid in a complex acoustic environment. BRIR measurements are recorded using the Head and Torso Simulator (HATS) for 17∼different receiver positions with a 5o angular resolution. Room impulse response measurements are also recorded using the Eigenmike for each of the 17 receiver positions. Using the Razer Anzu smart glasses to render the binaural AR spatial audio, we compare psychophysical performance on the shorelining navigation task using the recorded dataset and various existing binaural AR tool sets.

Young, K, Smith, R & Jackson, O 2023, 'The Broken Link: Overcoming Challenges to Successfully Engage with Allied Health Professionals in NSW Schools'.