Publications

BURNSTOCK, G, CAMPBELL, G, SATCHELL, D & SMYTHE, A 1970, 'Evidence that adenosine triphosphate or a related nucleotide is the transmitter substance released by non‐adrenergic inhibitory nerves in the gut', British Journal of Pharmacology, vol. 40, no. 4, pp. 668-688.
View/Download from: Publisher's site
View description>>

Summary. Stimulation of the vagal non‐adrenergic inhibitory innervation caused the release of adenosine and inosine into vascular perfusates from the stomachs of guinea‐pigs and toads.. Stimulation of portions of Auerbach's plexus isolated from turkey gizzard caused the release of adenosine triphosphate (ATP), adenosine diphosphate (ADP) and adenosine monophosphate (AMP).. ATP, added to solutions perfused through the toad stomach vasculature, was broken down to adenosine, inosine and adenine.. Of a series of purine and pyrimidine derivatives tested for inhibitory activity on the guinea‐pig isolated taenia coli, ATP and ADP were the most potent.. ATP caused inhibition of twelve other gut preparations previously shown to contain non‐adrenergic inhibitory nerves. The inhibitory action of ATP was not prevented by tetrodotoxin.. Quinidine antagonized relaxations of the guinea‐pig taenia coli caused by catecholamines or adrenergic nerve stimulation. Higher concentrations of quinidine antagonized relaxations caused by ATP or non‐adrenergic inhibitory nerve stimulation.. When tachyphylaxis to ATP had been produced in the rabbit ileum, there was a consistent depression of the responses to non‐adrenergic inhibitory nerve stimulation but not of responses to adrenergic nerve stimulation.. It is suggested that ATP or a related nucleotide is the transmitter substance released by the non‐adrenergic inhibitory innervation of the gut.

GOLDRING, ES, GROSSMAN, LI, KRUPNICK, D, CRYER, DR & MARMUR, J 1970, 'ETHIDIUM BROMIDE (EB) INDUCED BREAKDOWN OF YEAST MITOCHONDRIAL DNA (MDNA) DURING INDUCTION OF PETITES', FEDERATION PROCEEDINGS, vol. 29, no. 2, pp. A725-&.

GOLDRING, ES, GROSSMAN, LI, KRUPNICK, D, CRYER, DR & MARMUR, J 1970, 'PETITE MUTATION IN YEAST - LOSS OF MITOCHONDRIAL DEOXYRIBONUCLEIC ACID DURING INDUCTION OF PETITES WITH ETHIDIUM BROMIDE', JOURNAL OF MOLECULAR BIOLOGY, vol. 52, no. 2, pp. 323-&.
View/Download from: Publisher's site

Larkum, AWD & Hill, AE 1970, 'Ion and water transport in limonium. V. The ionic status of chloroplasts in the leaf of Limonium vulgare in relation to the activity of the salt glands', Biochimica et Biophysica Acta (BBA) - Biomembranes, vol. 203, no. 1, pp. 133-138.
View/Download from: Publisher's site
View description>>

A freeze-drying and non-aqueous extraction technique has been used to record the salt content of chloroplasts in leaf segments of Limonium vulgare. Changes in the level of K+, Na+ and Cl-were observed when leaf segments were treated with NaCl or KCl solutions which induce pumping of the salt glands. The effects of treatments designed to inhibit glandular activity are also recorded. Net accumulation of ions into chloroplasts is shown to be a process in vivo. The results provide evidence for a direct effect of glandular activity on cytoplasmic ion levels and they provide intracelluar evidence for the induction of glandular activity after a certain lag period. © 1970.

Leslie, LM, Morton, BR, Smith, RK, Wippermann, F, Berkofsky, L & Szillinsky, A 1970, 'On modelling tornadoes', Quarterly Journal of the Royal Meteorological Society, vol. 96, no. 409, pp. 544-548.
View/Download from: Publisher's site

SMITH, DA & SMITH, GB 1970, 'HIGH-TEMPERATURE PROPERTIES OF TRANSITION METAL ALLOYS', JOURNAL OF PHYSICS PART C SOLID STATE PHYSICS, vol. 3, no. 1, pp. S69-&.
View/Download from: Publisher's site