Publications

BAXTER, RC, AXIAK, S & RAISON, RL 1982, 'MONOCLONAL-ANTIBODY AGAINST HUMAN SOMATOMEDIN-C INSULIN-LIKE GROWTH FACTOR-I', JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, vol. 54, no. 2, pp. 474-476.
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Carroll, RJ 1982, 'Adapting for Heteroscedasticity in Linear Models', The Annals of Statistics, vol. 10, no. 4, pp. 1224-1233.
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Carroll, RJ 1982, 'Prediction and Power Transformations When the Choice of Power is Restricted to a Finite Set', Journal of the American Statistical Association, vol. 77, no. 380, pp. 908-915.
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We study the family of power transformations proposed by Box and Cox (1964) when the choice of the power parameter λ is restricted to a finite set Ω . The behavior of the Box-Cox procedure is as anticipated in two extreme cases: When the true parameter λ is an element of Ω and when λ is “far” from Ω We study the case in which λ is “close” to Ω , finding that the resulting methods can be very different from unrestricted maximum likelihood and that inferences may depend on the design, the values of the regression parameters, and the distance of λ to Ω . © 1982 Taylor & Francis Group, LLC. R R R. 0 R R

Carroll, RJ 1982, 'Robust estimation in certain heteroscedastic linear models when there are many parameters', Journal of Statistical Planning and Inference, vol. 7, no. 1, pp. 1-12.
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Carroll, RJ & Callo, PP 1982, 'Sow aspects of robustness in thr functional errors-in-variables regression model', Communications in Statistics - Theory and Methods, vol. 11, no. 22, pp. 2573-2585.
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Carroll, RJ & Ruppert, D 1982, 'A Comparison between Maximum Likelihood and Generalized Least Squares in a Heteroscedastic Linear Model', Journal of the American Statistical Association, vol. 77, no. 380, pp. 878-882.
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We consider a linear model with normally distributed but heteroscedastic errors. When the error variances are functionally related to the regression parameter, one can use either maximum likelihood or generalized least squares to estimate the regression parameter. We show that likelihood is more sensitive to small misspecifications in the functional relationship between the error variances and the regression parameter. © 1982 Taylor & Francis Group, LLC.

Carroll, RJ & Ruppert, D 1982, 'Weak convergence of bounded influence regression estimates with applications to repeated significance testing', Journal of Statistical Planning and Inference, vol. 7, no. 2, pp. 117-129.
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Catura, RC, Acton, LW, Brown, WA, Gilbreth, CW, Springer, LA, Vieira, JR, Culhane, JL, Mason, IW, Siegmund, O, Patrick, TJ, Sheather, PH, Pounds, KA, Cooke, BA, Evans, K, Pye, J, Smith, G, Wells, A, Spragg, JE, Whitford, CH, Franks, A, Gale, B, Lindsey, K, Stedman, M, Garmire, G, Margon, B & Fabian, A 1982, '<title>High Resolution Large Area Modular Array Of Reflectors (LAMAR) Wolter Type I X-Ray Telescope For Spacelab</title>', SPIE Proceedings, vol. 284, pp. 169-180.
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A Wolter type I X-ray telescope, intended both for astronomical observations and to serve as a prototype module for the Large Area Modular Array of Reflectors (LAMAR) mission, is now in definition study under NASA’s Spacelab program. The 5 mirror telescope presently being designed is to have a, blur circle radius of 20 arc sec rd an effective area of about 400 cm at 1/4 keV, 200 cm4 in the 0.5–2 keV range and 50 cm between 2 and 5 keV. Future expansion to a full 10 mirror telescope will approximately double these effective areas. A rotary interchange mechanism will allow either of two imaging proportional counters (IPCs) to be placed at the telescope focus; one operating between 0.15 and 2 keV and the other optimized for the 0.6 – 6 keV energy range. During flight, the telescope will utilize an instrument pointing system for a series of observations lasting from 6 minutes to several hours. This investigation has dual objectives: The primary objective is scientific and involves observational study of galactic and extragalactic X-ray sources, extending the work of the Einstein Observatory to much fainter sources and to higher energies. The second objective is to provide an assessment of the cost and improved performance of utilizing Wolter Type I X-ray optics for the LAMAR mission and to extend the technology for producing these optics to still higher angular resolution and toward lower cost. © 1982 SPIE.

COKER, DF, REIMERS, JR & WATTS, RO 1982, 'THE INFRARED-ABSORPTION SPECTRUM OF WATER', AUSTRALIAN JOURNAL OF PHYSICS, vol. 35, no. 5, pp. 623-638.
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Coombe, RG & George, AM 1982, 'Purification and properties of an aminoglycoside acetyltransferase from Pseudomonas aeruginosa', Biochemistry, vol. 21, no. 5, pp. 871-875.
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An aminoglycoside 3-acetyltransferase [AAC(3)], possibly a new isoenzymic species of the 3-N-acetyltransferase group, was purified to apparent homogeneity from a crude extract of Pseudomonas aeruginosa, a gentamicin-resistant clinical isolate. The method of purification was consecutive column chromatography—(i) gel filtration, (ii) affinity chromatography, and (iii) ion-exchange chromatography—to give two protein peaks, one of which was coincident with activity and which indicated a purification of 600 (specific activity = 9.743 units mg−1 at pH 7.2, 34 °C). Polyacrylamide disc gel electrophoresis indicated a single protein band coincident with enzymic activity. The molecular weight of the enzyme was about 39 000. AAC(3)-V (provisonal designation) was further characterized by stability, substrate, pH, and kinetic studies. The Km was 0.724 µM (sisomicin), and the Vmax was 0.102 µmol min−1 mg−1 (sisomicin) at pH 7.2 and 34 °C. Substrate inhibition was exhibited by kanamycin A and tobramycin. Studies showed that enzyme activity was significantly stabilized when preparations contained substrate. © 1982, American Chemical Society. All rights reserved.

Docherty, K, Carroll, RJ & Steiner, DF 1982, 'Conversion of proinsulin to insulin: involvement of a 31,500 molecular weight thiol protease.', Proceedings of the National Academy of Sciences, vol. 79, no. 15, pp. 4613-4617.
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A lysed crude secretory granule fraction from rat islets of Langerhans was shown to process endogenous proinsulin to insulin with a pH optimum of 5.0--6.0. The converting activity in the lysed fraction was not inhibited by serine protease inhibitors (diisopropyl fluorophosphate, soybean trypsin inhibitor, and aprotinin) or metalloprotease inhibitors (EDTA and o-phenanthroline) but was inhibited by some thiol protease reagents (p-chloromercuribenzenesulfonic acid, antipain, and leupeptin) but not by others (N-ethylmaleimide and iodoacetamide). N alpha-p-Tosyl-L-lysyl chloromethyl ketone only mildly inhibited at higher concentrations, whereas L-alanyl-L-lysyl-L-arginyl chloromethyl ketone was a powerful inhibitor. L-Alanyl-L-lysyl-L-arginyl chloromethyl ketone was [125I]iodotyrosylated and used as an affinity labeling agent for the converting activity. Because the crude granule preparation contained contaminating lysosomes the affinity labeling of the granule preparation proteins was compared with that in liver lysosomes purified from rats injected with Triton WR1339. In the crude granule fraction the affinity label bound in a cysteine-enhanced manner to a single 31,500 molecular weight protein, but in purified liver lysosomes the major affinity-labeled protein had a molecular weight of 25,000 and minor 31,500 and 35,000 molecular weight proteins were also labeled. Evidence suggests that these proteins are thiol proteases and that in islets the 31,500 molecular weight thiol protease is involved in the conversion of proinsulin to insulin.

ELIZUR, A, DENNIS, ES & PEACOCK, WJ 1982, 'SATELLITE DNA-SEQUENCES IN THE RED KANGAROO (MACROPUS-RUFUS)', AUSTRALIAN JOURNAL OF BIOLOGICAL SCIENCES, vol. 35, no. 3, pp. 313-325.
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FLICKER, W, MILTHORPE, BK, SCHINDHELM, K, ODELL, RA, MCPHERSON, J & FARRELL, PC 1982, 'PLATELET FACTOR RELEASE FOLLOWING HEPARIN ADMINISTRATION AND DURING EXTRACORPOREAL-CIRCULATION', TRANSACTIONS AMERICAN SOCIETY FOR ARTIFICIAL INTERNAL ORGANS, vol. 28, pp. 431-436.

Gerlach, WL, Pryor, AJ & Dennis, ES 1982, 'cDNA cloning and induction of the alcohol dehydrogenase gene (Adh1) of maize', Proceedings of the National Academy of Sciences of the United States of America, vol. 79, no. 9 I, pp. 2981-2985.
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cDNA clones of Adh1, one of two genes encoding alcohol dehydrogenase (ADH; alcohol:NAD+ oxidoreductase, EC 1.1.1.1) in the maize genome, have been isolated. They were derived from mRNA extracted from anaerobically treated roots of maize seedlings. Identification was initially made on the basis of molecular weight and electrophoretic properties of the in vitro polypeptide obtained in hybridization-release-translation experiments. The identification was confirmed by antibody precipitation and by the use of maize stocks having different genetic constitutions at the adh1 locus. The sequence of the longest cDNA segment, ≃900 base pairs, was determined and appears to code for 168 COOH-terminal amino acids and to have a 3' nontranslated region of 364 base pairs. Reverse Southern hybridizations established that two different adh1-S stocks produce a mRNA of 1,650 nucleotides, whereas an additional mRNA of 1,750 nucleotides is produced in three Adh1-F stocks. A 50-fold increase in Adh1 mRNA level occurs during anaerobiosis, reaching a maximum at 5 hr. Return to aerobic conditions indicates a half-life of more than 18 hr for the anaerobically induced Adh1 mRNA.

GERLACH, WL, PRYOR, AJ, DENNIS, ES, FERL, RJ, SACHS, MM & PEACOCK, WJ 1982, 'CDNA CLONING AND INDUCTION OF THE ALCOHOL-DEHYDROGENASE GENE (ADH1) OF MAIZE', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, vol. 79, no. 9, pp. 2981-2985.
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Hatcher, AI & Larkum, AWD 1982, 'The effects of short term exposure to bass strait crude oil and corexit 8667 on benthic community metabolism in Posidonia australis Hook.f. dominated microcosms', Aquatic Botany, vol. 12, no. C, pp. 219-227.
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Microcosms consisting of a sublittoral seagrass meadow from Botany Bay, N.S.W. were maintained in aquaria in a controlled environment room from March to August 1979. Oxygen production and consumption in the microcosms and leaf turnover of the seagrass, Posidonia australis Hook.f. were measured before, during and after a 7-day treatment in June with Bass Strait crude oil and the dispersant Corexit 8667. Four microcosms received oil and two of these received dispersant. The leaf turnover of P. australis was not significantly affected by the addition of oil and dispersant. Photosynthetic oxygen production decreased and respiration incresed in the microcosms during treatment. In August, 40 days after treatment, oxygen production rates and P/R ratios in the oil-treated microcosms were higher thatn rates measured before treatment. The oil-and-dispersant-treated microcosms did not show this trend. The results of this study indicate that a more severe stress is placed on the P. australis dominated benthic community by oil and dispersant than by oil alone. © 1982.

HOLMES, KT, HAMPSON, AW, RAISON, RL, WEBSTER, RG, OSULLIVAN, WJ & MOUNTFORD, CE 1982, 'A COMPARISON OF 2 ANTI-NEURAMINIDASE MONOCLONAL-ANTIBODIES BY COMPLEMENT ACTIVATION', EUROPEAN JOURNAL OF IMMUNOLOGY, vol. 12, no. 6, pp. 523-526.
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Leitch, EC & Willis, SGA 1982, 'Nature and significance of plutonic clasts in Devonian conglomerates of the New England Fold Belt', Journal of the Geological Society of Australia, vol. 29, no. 1-2, pp. 83-89.
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Granite, adamellite, granodiorite, quartz monzodiorite and quartz diorite clasts, together with much more abundant basic and intermediate volcanic detritus, occur in Devonian conglomerates in the New England Fold Belt, N.S.W. The plutonic material is of calc-alkaline type, characterised overall by high Fe/Mg ratios and low LIL abundances, and is geochemically more closely allied to plutonic rocks from island arcs than to those emplaced in continental crust. Small intrusive bodies em-placed within the volcanic chain to the west, which supplied most of the Devonian sedimentary material, are inferred to be the source of the plutonic debris. Geo-chemical characters and palaeogeographic relationships indicate that the clasts were not derived from Late Silurian gabbro-diorite-granodiorite intrusions in the northern part of the Lachlan Fold Belt. The absence of accompanying metasedimentary hornfels or metamorphic basement detritus also argues against a Lachlan source and a source in a basement terrain to the west of the New England Fold Belt. © Taylor & Francis Group, LLC.

Mazze, RI, Wilson, AI, Rice, SA & Baden, JM 1982, 'Reproduction and fetal development in mice chronically exposed to nitrous oxide', Teratology, vol. 26, no. 1, pp. 11-16.
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AbstractThe effects of exposure to nitrous oxide on reproductive indices, fetal development, and male fertility were examined in Swiss/ICR mice. In experiment I, female mice were exposed for 4 hours per day on days 6–15 of pregnancy, to 0.5% (5,000 ppm), 5.0% (50,000 ppm), or 50% (500,000 ppm) nitrous oxide. Control mice were untreated, exposed to compressed air, or treated with retinoic acid on day 8 of gestation. In experiment II, male mice were treated, as above, for 9 weeks and then mated nightly for 7 nights to untreated, virgin females. In experiment I, 1,761 fetuses from 154 dams were examined and found to be without evidence of adverse nitrous oxide treatment effects. In experiment II there were no differences among the groups in the ability of males to impregnate females or in litter size, fetal wastage, or fetal size. When we compare nitrous oxide with other inhalation anesthetics we have studied employing a similar protocol, we find the order of reproductive toxicity to be: halothane > enflurane > methoxyflurane > nitrous oxide. None of the agents were toxic, however, at the trace concentrations usually found in operating rooms.

MCKENZIE, DR, MCPHEDRAN, RC, BOTTEN, LC, SAVVIDES, N & NETTERFIELD, RP 1982, 'HYDROGENATED CARBON-FILMS PRODUCED BY SPUTTERING IN ARGON HYDROGEN MIXTURES', APPLIED OPTICS, vol. 21, no. 20, pp. 3615-3617.
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MCPHEDRAN, RC, BOTTEN, LC, CRAIG, MS, NEVIERE, M & MAYSTRE, D 1982, 'LOSSY LAMELLAR GRATINGS IN THE QUASI-STATIC LIMIT', OPTICA ACTA, vol. 29, no. 3, pp. 289-312.
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MOUNTFORD, CE, GROSSMAN, G, HOLMES, KT, OSULLIVAN, WJ, HAMPSON, AW, RAISON, RL & WEBSTER, R 1982, 'EFFECT OF MONOCLONAL ANTI-NEURAMINIDASE ANTIBODIES ON THE KINETIC-BEHAVIOR OF INFLUENZA-VIRUS NEURAMINIDASE', MOLECULAR IMMUNOLOGY, vol. 19, no. 6, pp. 811-816.
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Peacock, WJ, Dennis, ES & Gerlach, WL 1982, 'DNA sequence changes and speciation.', Prog Clin Biol Res, vol. 96, pp. 123-142.

Platen, E 1982, 'A generalized Taylor formula for solutions of stochastic differential equations', Sankhya A - Mathematical Statistics and Probability, vol. 44, no. 2, pp. 163-172.

Platen, E 1982, 'An approximation method for a class of Ito processes with jump component', Lithuanian Mathematical Journal, vol. 22, no. 2, pp. 124-136.

Platen, E & Wagner, W 1982, 'On a Taylor formula for a class of Ito processes', Probability and Mathematical Statistics, vol. 3, no. 1, pp. 37-51.

RAISON, RL, WALKER, KZ, HALNAN, CRE, BRISCOE, D & BASTEN, A 1982, 'LOSS OF SECRETION IN MOUSE-HUMAN HYBRIDS NEED NOT BE DUE TO THE LOSS OF A STRUCTURAL GENE', JOURNAL OF EXPERIMENTAL MEDICINE, vol. 156, no. 5, pp. 1380-1389.
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REIMERS, JR, WATTS, RO & KLEIN, ML 1982, 'INTERMOLECULAR POTENTIAL FUNCTIONS AND THE PROPERTIES OF WATER', CHEMICAL PHYSICS, vol. 64, no. 1, pp. 95-114.
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Rice, SA, Playford, VJ, Burns, WG & Buxton, GV 1982, 'Nanosecond proton pulse radiolysis', Journal of Physics E: Scientific Instruments, vol. 15, no. 11, pp. 1240-1243.
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SMITH, GB, ZAJAC, G & IGNATIEV, A 1982, 'HIGH-FLUX PHOTOCHEMICAL CHANGES IN BLACK CHROME SOLAR ABSORBING COATINGS', SOLAR ENERGY, vol. 29, no. 4, pp. 279-289.
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SMITH, GB, ZAJAC, G, IGNATIEV, A & RABALAIS, JW 1982, 'SURFACE-COMPOSITION OF SOLAR SELECTIVE BLACK CHROME FILMS AS DETERMINED BY SIMS', SURFACE SCIENCE, vol. 114, no. 2-3, pp. 614-626.
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WHITE, MJD, DENNIS, ES, HONEYCUTT, RL, CONTRERAS, N & PEACOCK, WJ 1982, 'CYTOGENETICS OF THE PARTHENOGENETIC GRASSHOPPER WARRAMABA-VIRGO AND ITS BISEXUAL RELATIVES .9. THE RIBOSOMAL-RNA CISTRONS', CHROMOSOMA, vol. 85, no. 2, pp. 181-199.
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Zinder, Y 1982, 'Topological Sorting', Programming and Computer Software, vol. 6.

Zinder, YA 1982, 'ALPHA-TOPOLOGICAL SORTING.', Programming and Computer Software (English Translation of Programmirovanie), vol. 8, no. 6, pp. 346-348.
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The complexity of alpha-topological sorting is investigated. An effective algorithm of alpha-topological sorting is proposed and its application domain is described.