Publications

APPELS, R, DENNIS, ES, SMYTH, DR & PEACOCK, WJ 1981, '2 REPEATED DNA-SEQUENCES FROM THE HETEROCHROMATIC REGIONS OF RYE (SECALE-CEREALE) CHROMOSOMES', CHROMOSOMA, vol. 84, no. 2, pp. 265-277.
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Balasubramaniam, S, Beins, DM & Simons, LA 1981, 'On the mechanism of plasma cholesterol reduction in the rat given probucol.', Clinical science (London, England : 1979), vol. 61, no. 5, pp. 615-619.
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1. The effects of the cholesterol-lowering drug probucol on lipoprotein metabolism and on the key enzymes that regulate hepatic cholesterol metabolism in the rat were studied. 2. Probucol given for 2 weeks was accompanied by a significant reduction in plasma concentrations of low-density and high-density lipoproteins (LDL,HDL). The fractional catabolic rates of the apolipoproteins of HDL and LDL (apoHDL, apoLDL) were not affected by probucol, although the absolute rates of catabolism of both the apolipoproteins were significantly reduced. 3. The activities of 3-hydroxy-3-methylglutaryl-coenzyme A (CoA) reductase and cholesterol 7 alpha-mono-oxygenase, as well as the rate of hepatic sterol synthesis, were unchanged during the first 2 weeks of probucol. More prolonged probucol led to inhibition of the activity of these enzymes and reduction in sterol synthesis, although the liver cellular content of cholesterol significantly increased. 4. It is postulated that a principal mode of action of the drug is to reduce the rate of lipoprotein synthesis.

Barrett, RP, Matson, JL, Shapiro, ES & Ollendick, TH 1981, 'A comparison of punishment and DRO procedures for treating stereotypic behavior of mentally retarded children', Applied Research In Mental Retardation, vol. 2, no. 3, pp. 247-256.
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In the present study, two mentally retarded children with high rare stereotypic responding were hospitalized in a university medical school setting and treated with punishment and differential reinforcement of other behavior (DRO). Differential impact of the two treatment conditions was assessed using an alternating treatments design that incorporated the use of condition-specific discriminative stimuli. Experimental control was established through the use of a separate condition of no treatment. Results of the study indicated that for both subjects, all conditions were clearly discriminated and that punishment procedures were more effective for suppressing stereotypies than DRO. Six-month follow-up data were reported. Implications for future research utilizing the alternating treatments design were also discussed. © 1981.

BENNETT, AF & LESLIE, LM 1981, 'STATISTICAL CORRECTION OF THE AUSTRALIAN REGION PRIMITIVE EQUATION MODEL', MONTHLY WEATHER REVIEW, vol. 109, no. 3, pp. 453-462.
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BOTTEN, IC, CRAIG, MS, MCPHEDRAN, RC, ADAMS, JL & ANDREWARTHA, JR 1981, 'THE DIELECTRIC LAMELLAR DIFFRACTION GRATING', OPTICA ACTA, vol. 28, no. 3, pp. 413-428.
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BOTTEN, LC, CRAIG, MS & MCPHEDRAN, RC 1981, 'HIGHLY CONDUCTING LAMELLAR DIFFRACTION GRATINGS', OPTICA ACTA, vol. 28, no. 8, pp. 1103-1106.
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BOTTEN, LC, CRAIG, MS, MCPHEDRAN, RC, ADAMS, JL & ANDREWARTHA, JR 1981, 'THE FINITELY CONDUCTING LAMELLAR DIFFRACTION GRATING', OPTICA ACTA, vol. 28, no. 8, pp. 1087-1102.
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BRILES, DE & CARROLL, RJ 1981, 'A SIMPLE METHOD FOR ESTIMATING THE PROBABLE NUMBERS OF DIFFERENT ANTIBODIES BY EXAMINING THE REPEAT FREQUENCIES OF SEQUENCES OR ISOELECTRIC-FOCUSING PATTERNS', MOLECULAR IMMUNOLOGY, vol. 18, no. 1, pp. 29-38.
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CARROLL, RJ & RUPPERT, D 1981, 'ON PREDICTION AND THE POWER TRANSFORMATION FAMILY', BIOMETRIKA, vol. 68, no. 3, pp. 609-615.
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Chappell, P, Fischer, G, Reimers, JR & Ross, I 1981, 'Electronic-Spectrum Of 1,5-Naphthyridine - Theoretical Treatment Of Vibronic Coupling', Journal Of Molecular Spectroscopy, vol. 87, no. 2, pp. 316-330.
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Cheung, H & Ryan, LM 1981, 'A Method Of Determining Dna And Chondrocyte Content Of Articular-Cartilage', Analytical Biochemistry, vol. 116, no. 1, pp. 93-97.
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Coombe, RG & George, AM 1981, 'Enzymic determination of gentamicin in human plasma', Australian Journal of Pharmaceutical Sciences, vol. 10, no. 4, pp. 98-100.

Coombe, RG & George, AM 1981, 'Mass spectral and ¹³c n.m.r. analyses of aminoglycoside aminocyclitols modified by enzyme-catalysed reactions', Australian Journal of Chemistry, vol. 34, no. 3, pp. 547-554.
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Chemical and physical analytical methods, including mass spectrometry and 13C nnr., have been applied to the evaluation of the structures of the inactivated products of enzyme-mediated trans-ferase reactions. Evidence is presented for the assignment of structures for the products of three enzymic reaction mechanisms: O-adenylylation, O-phosphorylation and N-acetylation. © 1981, CSIRO. All rights reserved.

Coombe, RG & George, AM 1981, 'New plasmid-mediated aminoglycoside adenylyltransferase of broad substrate range that adenylylates amikacin', Antimicrobial Agents and Chemotherapy, vol. 20, no. 1, pp. 75-80.
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The same aminoglycoside 2''-adenyltransferase was isolated from 4 gram-negative species which were among a random group of gentamicin-resistant isolates from the same hospital. The enzyme was partially purified from a crude extract which also contained a second modifying enzyme identified as APH(3')-I. The substrate range of the new aminoglycoside 2''-adenylyltransferase included the newer aminoglycosides sisomicin and amikacin, but showed much-reduced activity against gentamicin C2 and C1a. The pH optimum was 7.8 to 8.0 for every substrate, and the molecular weight of the enzyme molecule was estimated at approximately 29,000. Genetic experiments clearly established that both enzymes were expressed by a conjugative plasmid.

DENNIS, ES, PEACOCK, WJ, WHITE, MJD, APPELS, R & CONTRERAS, N 1981, 'CYTOGENETICS OF THE PARTHENOGENETIC GRASSHOPPER WARRAMABA-VIRGO AND ITS BISEXUAL RELATIVES .7. EVIDENCE FROM REPEATED DNA-SEQUENCES FOR A DUAL ORIGIN OF W-VIRGO', CHROMOSOMA, vol. 82, no. 4, pp. 453-469.
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Fischer, G, Reimers, JR & Ross, I 1981, 'Cndo-Calculation Of 2Nd-Order Vibronic Coupling In The 1B2U-1A1G Transition Of Benzene', Chemical Physics, vol. 62, no. 1-Feb, pp. 187-193.
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Gladstone, W 1981, 'Early medical photography in America (1839--1883); VI. Civil war medical photography.', New York State Journal of Medicine, vol. 81, no. 1.

Green, PJ 1981, 'Modeling yeast-cell growth using stochastic branching-processes', Journal Of Applied Probability, vol. 18, no. 4, pp. 799-808.
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HOOTON, TM, HALEY, RW, CULVER, DH, WHITE, JW, MORGAN, WM & CARROLL, RJ 1981, 'THE JOINT ASSOCIATIONS OF MULTIPLE RISK-FACTORS WITH THE OCCURRENCE OF NOSOCOMIAL INFECTION', AMERICAN JOURNAL OF MEDICINE, vol. 70, no. 4, pp. 960-970.
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Leitch, EC 1981, 'Quartz-albite rocks of ash-fall origin', Geological Magazine, vol. 118, no. 1, pp. 83-88.
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Thin beds composed mainly of quartz and albite occur interstratified with epiclastic rocks in a thick marine Early Permian sequence in the eastern part of the New England Fold Belt, eastern Australia. The sequence has suffered very low grade regional metamorphism and the quartz-albite rocks retain few primary textural features. A pyroclastic origin for these rocks is argued on the basis of inherited sedimentary characters and their distinctive mineralogical and chemical composition, and it is suggested that they accumulated as glass-rich ash-fall tuffs. The present chemical composition of the quartz-albite rocks suggests the tuffs may have initially altered to zeolitic assemblages. Similar quartz-albite rocks, perhaps misidentified as chert or siliceous siltstone, probably occur in other low-grade metamorphic sequences, the progenitors of which accumulated adjacent to active magmatic arcs. © 1981, Cambridge University Press. All rights reserved.

Leslie, LM, Mills, GA & Gauntlett, DJ 1981, 'The impact of FGGE data coverage and improved numerical techniques in numerical weather prediction in the Australian region', Quarterly Journal of the Royal Meteorological Society, vol. 107, no. 453, pp. 629-642.
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This paper describes the results from an extensive series of experiments aimed at enhancing the skill of the Australian Numerical Meteorology Research Centre (ANMRC) limited area analysis/forecast system. Significant increases in model performance were achieved, in the sense of reducing S1, skill scores and in forecasting precipitation, in three ways: (1) improved data base since the beginning of FGGE; (2) the application of a more realistic lateral boundary specification, particularly nesting within a hemispheric forecast model; and (3) the reduction of truncation errors by either decreasing the grid spacing or (more efficiently) employing higher order difference operators. The improvement in skill is sufficiently large to suggest that when implemented operationally the quality of routine prediction of synoptic scale patterns over the Australian region will be considerably improved. Copyright © 1981 Royal Meteorological Society

LESLIE, LM, MILLS, GA & GAUNTLETT, DJ 1981, 'THE IMPACT OF FGGE DATA COVERAGE AND IMPROVED NUMERICAL TECHNIQUES IN NUMERICAL WEATHER PREDICTION IN THE AUSTRALIAN REGION', QUARTERLY JOURNAL OF THE ROYAL METEOROLOGICAL SOCIETY, vol. 107, no. 453, pp. 629-642.
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LOUIS, CJ, WYLLIE, RG, CHOU, ST & SZTYNDA, T 1981, 'LECTIN-BINDING AFFINITIES OF HUMAN EPIDERMAL TUMORS AND RELATED CONDITIONS', AMERICAN JOURNAL OF CLINICAL PATHOLOGY, vol. 75, no. 5, pp. 642-647.
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MAY, V & LARKUM, AWD 1981, 'A subtidal transect in Jervis Bay, New South Wales', Australian Journal of Ecology, vol. 6, no. 4, pp. 439-457.
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Long‐term variations in the intertidal algal flora of the entire rock platform at Plantation Point, Jervis Bay, are described by May (1981). The study now reported presents similar long‐term changes in the flora of a subtidal region of the same headland, observed within the same period of time. This first detailed report of subtidal macroalgal communities in New South Wales describes a several‐year study of the benthic communities along a transect in the upper sublittoral region of a rocky headland at Plantation Point, Jervis Bay. Eighty‐nine species of algae were recorded, five of which were previously unrecorded for New South Wales. The area studied is dominated by the large brown algae Ecklonia radiata and Phyllospora comosa, large areas of which were cleared periodically by storms. Turf, shade and crustose coralline algal communities also were present. Storms, seasonal variation and longer term changes all affected the abundance and distribution of the algal species growing along the transect and hence the floristic composition of the area. Copyright © 1981, Wiley Blackwell. All rights reserved

Nelson, S & Green, PJ 1981, 'The random transition model of the cell-cycle - A critical-review', Cancer Chemotherapy And Pharmacology, vol. 6, no. 1, pp. 11-18.
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Novikov, AA 1981, 'On estimates and the asymptotic behavior of nonexit probabilities of a wiener process to a moving boundary', Mathematics of the USSR - Sbornik, vol. 38, no. 4, pp. 495-505.
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In this paper the asymptotic behavior, as well as upper and lower bounds, is found for the probabilities P(σ > T) = P(lW, l < f(t), 0 T) = P(W,> g(t), 0 < t < T) for large classes of functions/and g. © 1981 American Mathematical Society.

Novikov, AA 1981, 'On estimates and the asymptotic behavior of the probability of nonintersection of moving boundaries by sums of independent random variables', Mathematics of the USSR - Izvestija, vol. 17, no. 1, pp. 129-145.
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This paper studies estimates and the asymptotic behavior as n → ∞ for the probabilities P(Sk < f(k), m < k < n) and P(Sk > g(k), m < k < n), where (formula omitted) being independent identically distributed random variables with mean zero, and f(n) and g(n) are nonrandom functions. Under certain restrictions on the boundaries f(n) and g(n) logarithmic asymptotes of these probabilities are found in the case when the ξk satisfy (respectively) a two-sided or a one-sided Cramer condition. The method is based on an absolutely continuous substitution for the original probability measure. © 1981 American Mathematical Society.

Novikov, AA 1981, 'Small deviations of Gaussian process', Mathematical Notes of the Academy of Sciences of the USSR, vol. 29, no. 2, pp. 150-155.
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Ollendick, TH 1981, 'Self-Monitoring and Self-Administered Overcorrection: The Modification of Nervous Tics in Children', Behavior Modification, vol. 5, no. 1, pp. 75-84.
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The relative contribution of self-monitoring and competing response practice to the effectiveness of the Azrin and Nunn (1973, 1977) habit-reversal procedure was investigated in two children exhibiting nervous tics. A multiple baseline design across settings was employed for each child and the reliability of self-monitoring was determined. Results indicated that both children were capable of reliable self-monitoring and that self-monitoring alone was sufficient to reduce tics in one of the children. For the other child, who presented a longer history of tics, it was necessary to include competing response practice with the self-monitoring. For both children, change was setting specific. Issues of generalization were discussed. © 1981, Sage Publications. All rights reserved.

Ollendick, TH, Shapiro, ES & Barrett, RP 1981, 'Reducing stereotypic behaviors: An analysis of treatment procedures utilizing an alternating treatments design', Behavior Therapy, vol. 12, no. 4, pp. 570-577.
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The present study examined the utility of the alternating treatments design by comparing physical restraint and positive practice overcorrection to a "no treatment" condition in the reduction of stereotypic behavior. Both active treatments were more effective than no treatment, and the treatments were differentially effective for different children. © 1981 Association for Advancement of Behavior Therapy. All rights reserved.

PEACOCK, WJ, APPELS, R, ENDOW, S & GLOVER, D 1981, 'CHROMOSOMAL DISTRIBUTION OF THE MAJOR INSERT IN DROSOPHILA-MELANOGASTER 28S RIBOSOMAL-RNA GENES', GENETICAL RESEARCH, vol. 37, no. 2, pp. 209-&.
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PEACOCK, WJ, DENNIS, ES, ELIZUR, A & CALABY, JH 1981, 'REPEATED DNA-SEQUENCES AND KANGAROO PHYLOGENY', AUSTRALIAN JOURNAL OF BIOLOGICAL SCIENCES, vol. 34, no. 3, pp. 325-340.
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PEACOCK, WJ, DENNIS, ES, RHOADES, MM & PRYOR, AJ 1981, 'HIGHLY REPEATED DNA-SEQUENCE LIMITED TO KNOB HETEROCHROMATIN IN MAIZE', PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, vol. 78, no. 7, pp. 4490-4494.
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Perez, DJ, Taylor, IW, Milthorpe, BK, McGovern, VJ & Tattersall, MH 1981, 'Identification and quantitation of tumour cells in cell suspensions: a comparison of cytology and flow cytometry', British Journal Of Cancer, vol. 43, no. 4, pp. 526-531.
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FLOW-CYTOMETRIC MEASUREMENTS of cell DNA content or narrow-angle light scatter (NLS) can provide a basis for discriminating neoplastic from non-neoplastic cells by identifying differences in DNA content and cell size. Flow-cytometric analyses of many human neoplasms have been previously reported (Barlogie et at., 977, 1978) showing aneuploidy in 80-90% of non-lymphoid solid tumours and 40- 60% of non-Hodgkin's lymphomas. In leukaemias, and multiple myelomas with and aneuploid tumour clone, the percentage of neoplastic cells in marrow or blood determined by DNA content correlates well with quantitation based on histologic smears (Barlogie et al., 1977; Latreille et al., 1980; Andreeff et al., 1980) but such a comparison has not been made on cell suspensions from solid tumours.

PIPER, AA, MILTHORPE, BK & FOX, RM 1981, 'MECHANISMS OF FLUOROURACIL CYTO-TOXICITY IN CULTURED HUMAN LYMPHOCYTE-T AND LYMPHOCYTE-B', CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, vol. 8, no. 4, pp. 385-385.

Platen, E 1981, 'An approximation method for a class of Ito processes', Lithuanian Mathematical Journal, vol. 21, pp. 121-133.

PRYOR, A, GERLACH, W, DENNIS, E & PEACOCK, W 1981, 'CDNA CLONES SPECIFYING MAIZE ALCOHOL-DEHYDROGENASE', PROCEEDINGS OF THE AUSTRALIAN BIOCHEMICAL SOCIETY, vol. 14, pp. 105-105.

Simons, LA, Balasubramaniam, S & Beins, DM 1981, 'Metabolic studies with probucol in hypercholesterolaemia.', Atherosclerosis, vol. 40, no. 3-4, pp. 299-308.
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Probucol (1 g/day) was administered for 6 months to 16 hypercholesterolaemic patients previously stabilized on diet alone. Total plasma cholesterol fell by 16%, LDL cholesterol by 14% and HDL cholesterol by 41%. The ratio of total cholesterol to HDL cholesterol increased by 40%. Total plasma triglycerides showed a slight upward trend. The extent of the fall in HDL cholesterol was directly proportional to the pre-treatment HDL cholesterol concentration. In 2 patients studied, treatment with Probucol produced a sustained increase in the excretion of endogenous faecal steroids, due to increased faecal bile acids. In 3 patients studied, Probucol increased the degree of cholesterol saturation in gall bladder bile. The Lithogenic Index approximated to pathological levels in 1 patient whose bile was previously relatively saturated with cholesterol. Probucol also appeared to cause a modest reduction in the degree of platelet activation in vivo, with reduced platelet prostaglandin synthesis and reduced release of platelet peptides.

SMITH, GB & IGNATIEV, A 1981, 'BLACK CHROMIUM-MOLYBDENUM - A NEW STABLE SOLAR-ABSORBER', SOLAR ENERGY MATERIALS, vol. 4, no. 2, pp. 119-133.
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STEFFENSEN, DM, APPELS, R & PEACOCK, WJ 1981, 'THE DISTRIBUTION OF 2 HIGHLY REPEATED DNA-SEQUENCES WITHIN DROSOPHILA-MELANOGASTER CHROMOSOMES', CHROMOSOMA, vol. 82, no. 4, pp. 525-541.
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STEWART, GA, RAWLINS, WHM, QUICK, GR, BEGG, JE & PEACOCK, WJ 1981, 'OILSEEDS AS A RENEWABLE SOURCE OF DIESEL FUEL', SEARCH, vol. 12, no. 5, pp. 107-115.

VENOLIA, L & PEACOCK, WJ 1981, 'A HIGHLY REPEATED DNA FROM THE GENOME OF THE WALLAROO (MACROPUS-ROBUSTUS-ROBUSTUS)', AUSTRALIAN JOURNAL OF BIOLOGICAL SCIENCES, vol. 34, no. 1, pp. 97-113.
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ZAJAC, G, IGNATIEV, A & SMITH, GB 1981, 'PHOTODESORPTION STUDIES OF CO AND CO2 FROM THE SOLAR-ABSORBER BLACK CHROME', JOURNAL OF VACUUM SCIENCE & TECHNOLOGY, vol. 18, no. 2, pp. 379-381.
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ZELYAKH, EV & NOVIKOV, AA 1981, 'ACTIVE WIDE-BAND PIEZOELECTRIC FILTERS.', TELECOMMUN RADIO ENG, vol. V 35-36, no. N 10, pp. 47-51.
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A METHOD IS DESCRIBED FOR OBTAINING WIDE-BAND FILTERS WHICHIS BASED ON THE USE OF NEGATIVE CAPACITANCE FOR WIDENING THE RESONANCE INTERVAL OF THE PIEZOELECTRIC RESONATOR.